Affiliation: Frankfurt am Main
- Labyrinth anesthesia--a forgotten but practical treatment option in Ménière's diseaseOliver Adunka
ENT Department, University Clinic Frankfurt am Main, Frankfurt M, Germany
ORL J Otorhinolaryngol Relat Spec 65:84-90. 2003..Based on the findings presented herein, we consider labyrinth anesthesia a practicable and, due to its safety, highly recommendable therapeutic option for patients suffering from Ménière's disease...
- Predicting basal cochlear length for electric-acoustic stimulationOliver Adunka
Department of Otorhinolaryngology, J W Goethe University, Frankfurt am Main, Germany
Arch Otolaryngol Head Neck Surg 131:488-92. 2005..To assess the feasibility and accuracy of predicting electrode insertion depth necessary in cochlear implantations for electric-acoustic stimulation by means of preoperative high-resolution computed tomography (HRCT)...
- Evaluating cochlear implant trauma to the scala vestibuliO Adunka
Clinic of Otolaryngology, Head and Neck Surgery, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
Clin Otolaryngol 30:121-7. 2005..The aim of this study was to evaluate the morphological consequences and cochlear trauma after implantation of different cochlear implant electrode arrays in the scala vestibuli...
- Preservation of basal inner ear structures in cochlear implantationOliver Adunka
ENT Department, J W Goethe University, Frankfurt am Main, Germany
ORL J Otorhinolaryngol Relat Spec 66:306-12. 2004....
- [Evaluation of an electrode design for the combined electric-acoustic stimulation]O Adunka
HNO Universitätsklinik, J W Goethe Universität Frankfurt am Main, Frankfurt am Main
Laryngorhinootologie 83:653-8. 2004....
- Cochlear implantation via the round window membrane minimizes trauma to cochlear structures: a histologically controlled insertion studyOliver Adunka
ENT Department, J W Goethe University, Frankfurt am Main, Germany
Acta Otolaryngol 124:807-12. 2004..To evaluate cochlear implant trauma to intracochlear structures when inserting the electrode via the round window membrane...
- Development and evaluation of an improved cochlear implant electrode design for electric acoustic stimulationOliver Adunka
ENT Department, J W Goethe University Frankfurt am Main, Frankfurt am Main, Germany
Laryngoscope 114:1237-41. 2004..Special emphasis was placed on the practicality for combined electric and acoustic stimulation of the auditory system...
- [Adonco. A clinical-scientific database system for the acquisition and analysis of oncologic data in head and neck regions]O Adunka
HNO Universitätsklinik der Johann Wolfgang Goethe Universität Frankfurt am Main
HNO 53:39-45. 2005..Our aim was to design and develop a computer database system for head and neck cancer patients for clinical and scientific use...
- Expression of hypoxia inducible factor 1 alpha and Von Hippel Lindau protein in human middle ear cholesteatomaOliver Adunka
Department of Otorhinolaryngology, J W Goethe University Clinic Frankfurt am Main, Theodor Stern Kai 7, D 60590 Frankfurt am Main, Germany
Laryngoscope 113:1210-5. 2003..To evaluate the role of hypoxia in cholesteatoma progression...
- [Cochlear implantation with preservation of residual deep frequency hearing]W Gstöttner
HNO Universitätsklinik, Klinikum der J W Goethe Universitat, Frankfurt am Main
HNO 53:784-90. 2005..The aim of the present paper is to evaluate the clinical parameters in patients implanted for combined, ipsilateral electric-acoustic stimulation of the auditory system...
- Hearing preservation in cochlear implantation for electric acoustic stimulationWolfgang Gstoettner
ENT Department, Head and Neck Surgery, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
Acta Otolaryngol 124:348-52. 2004..To evaluate the possibility of preservation of low-frequency hearing in atraumatic cochlear implant electrode insertion procedures for combined, ipsilateral electric and acoustic stimulation...
- Carcinomas unresponsive to either cisplatinum or anti-EGFR therapy can be growth inhibited by combination therapy of both agentsR Knecht
Department of Otorhinolaryngology, University of Frankfurt, Medical School, 60590 Frankfurt/M, Germany
Anticancer Res 23:2577-83. 2003..DISCUSSION: The obtained results may address upcoming phase I/II trials to use Anti-EGFR/Cisplatinum therapy regardless of the EGFR content of tumors...
- STAT 3 activation in head and neck squamous cell carcinomas is controlled by the EGFRMarkus Hambek
Department of Otorhinolaryngology, School of Medicine, J W Goethe University, 60590 Frankfurt, Germany
Anticancer Res 24:3881-6. 2004..These findings provide evidence that STAT 3 signal activity in head and neck carcinomas, which is partially responsible for proliferative activity, can be controlled via the EGFR...
- Iressa (ZD 1839) inhibits phosphorylation of three different downstream signal transducers in head and neck cancer (SCCHN)Markus Hambek
Department of Otorhinolaryngology, School of Medicine, J. W. Goethe University, 60590 Frankfurt, Germany
Anticancer Res 25:1871-5. 2005..We conclude that Iressa has a high potency to inhibit nuclear gene transcription responsible for cell cycle progression. Furthermore, dose reduction of Iressa in the case of toxicity may not severely influence the response to treatment...
- Combined electric and acoustic stimulation of the auditory system: results of a clinical studyJan Kiefer
Klinik und Poliklinik für Hals Nasen Ohrenheilkunde des Klinikums r d Isar, Technische Universitat, Munchen, Deutschland
Audiol Neurootol 10:134-44. 2005..Synergistic effects of EAS were most prominent for hearing in noise with increases of up to 72% as compared to cochlear implant alone...
- AdOnco: a database for clinical and scientific documentation of head and neck oncologyMarkus Hambek
Department of Otolaryngology-Head and Neck Surgery, University of Frankfurt, Frankfurt/Main, Germany
Ann Otol Rhinol Laryngol 115:144-9. 2006..The combination of clinical and scientific features proved to be very effective in daily routine and research...
- Impact of electrode insertion depth on intracochlear traumaOliver Adunka
Department of Otolaryngology, Head and Neck Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7070, USA
Otolaryngol Head Neck Surg 135:374-82. 2006..To assess the effect of cochlear implant (CI) insertion depth and surgical technique on intracochlear trauma...
- Representation of acoustic signals in the human cochlea in presence of a cochlear implant electrodeJan Kiefer
Department of Otolaryngology, Klinikum rechts der Isar, Technical University Munich, Ismaninger Strasse 22, D 81675 Munich, Germany
Hear Res 221:36-43. 2006..Intracochlear introduction of a cochlear implant electrode, however, may alter the biomechanical properties of the inner ear and thus affect perception of acoustic stimuli...
- Monitoring of cochlear function during cochlear implantationOliver Adunka
Department of Otolaryngology-Head and Neck Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7600, USA
Laryngoscope 116:1017-20. 2006..Ultimately, profound hearing loss was documented, indicating that factors other than immediate changes induced by electrode insertion were likely responsible for the loss of cochlear function...