Fillies T, Werkmeister R, van Diest P, Brandt B, Joos U, Buerger H. HIF1-alpha overexpression indicates a good prognosis in early stage squamous cell carcinomas of the oral floor. BMC Cancer. 2005;5:84 pubmed
..05). HIF-1alpha overexpression is an indicator of favourable prognosis in T1 and T2 SCC of the oral floor. Node negative patients lacking HIF-1alpha expression may therefore be considered for adjuvant radiotherapy. ..
Fillies T, Werkmeister R, Packeisen J, Brandt B, Morin P, Weingart D, et al
. Cytokeratin 8/18 expression indicates a poor prognosis in squamous cell carcinomas of the oral cavity. BMC Cancer. 2006;6:10 pubmed
..These results provide an extended knowledge about the role of intermediary filament expression patterns in SCC's. ..
Fillies T, Buerger H, Gaertner C, August C, Brandt B, Joos U, et al
. Catenin expression in T1/2 carcinomas of the floor of the mouth. Int J Oral Maxillofac Surg. 2005;34:907-11 pubmed
..Loss of gamma-catenin expression indicated a reduced survival rate in nodal-negative tumours (P=0.02). Catenin expression in carcinomas of the floor of the mouth seems to be a predictive parameter in the prognosis of T1 and T2 SSCs. ..
Fillies T, Woltering M, Brandt B, Van Diest J, Werkmeister R, Joos U, et al
. Cell cycle regulating proteins p21 and p27 in prognosis of oral squamous cell carcinomas. Oncol Rep. 2007;17:355-9 pubmed
..03). p21 and p27 in carcinoma of oral cavity seem to be predictive parameter in regulation and prognosis of squamous cell carcinomas. A p21 negative subgroup of OSCC may benefit from additional radio or radiochemotherapy. ..
Fillies T, Jogschies M, Kleinheinz J, Brandt B, Joos U, Buerger H. Cytokeratin alteration in oral leukoplakia and oral squamous cell carcinoma. Oncol Rep. 2007;18:639-43 pubmed
..These results can be interpreted as first hints that oral leukoplakias with an expression of Ck 8/18 or 19 independent of dysplasia, should be resected totally since they might indicate an increased progression potential...