Research Topics
Species | Joachim FensterleSummaryCountry: Germany Publications
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Publications
HLA-B8 association with late-stage melanoma--an immunological lesson?Joachim Fensterle
Inst f Med Strahlenkunde und Zellforschung MSZ, University Clinics of Würzburg, Versbacher Str 5, 97078 Wurzburg, Germany
BMC Med 4:5. 2006..This retrospective study is intended to detect differences in MHC class I carrier frequencies of advanced melanoma patients compared to healthy bone marrow donors...
[A trip through the signaling pathways of melanoma]Joachim Fensterle
Universitat Wurzburg, Institut für Med Strahlenkunde und Zellforschung MSZ, Wurzburg
J Dtsch Dermatol Ges 4:205-17. 2006..In addition, new therapeutic options based on the knowledge of signaling pathways will be discussed...
B-Raf specific antibody responses in melanoma patientsJoachim Fensterle
Institut für Medizinische Strahlenkunde und Zellforschung MSZ, University Clinics of Würzburg, Versbacher Str 5, 97078 Wurzburg, Germany
BMC Cancer 4:62. 2004....
Specific antibody-receptor interactions trigger InlAB-independent uptake of Listeria monocytogenes into tumor cell linesMartin Heisig
Institut für Medizinische Strahlenkunde und Zellforschung MSZ, Universitat Wurzburg, Versbacher Strasse 8, Wurzburg, 97078, Deutschland
BMC Microbiol 11:163. 2011....
Improvement of the live vaccine strain Salmonella enterica serovar Typhi Ty21a for antigen delivery via the hemolysin secretion system of Escherichia coliChristian Hotz
Institut fur Medizinische Strahlenkunde und Zellforschung, University of Wurzburg, Wurzburg, Germany
Int J Med Microbiol 299:109-19. 2009..typhi strain secreting HlyA compared with the same strain without rfaH plasmid...
Shigella mediated depletion of macrophages in a murine breast cancer model is associated with tumor regressionKatharina Galmbacher
Institut fur Medizinische Strahlenkunde und Zellforschung, Universitat Wurzburg, Wurzburg, Germany
PLoS ONE 5:e9572. 2010..TAM depletion was sustained and associated with complete tumor regression.These data support TAMs as useful targets for antitumor therapy and highlight attenuated bacterial pathogens as potential tools...
Use of the alpha-hemolysin secretion system of Escherichia coli for antigen delivery in the Salmonella typhi Ty21a vaccine strainIvaylo Gentschev
Institut fur Medizinische Strahlenkunde und Zellforschung, University of Wurzburg, Versbacher Str 5, D 97078 Wurzburg, Germany
Int J Med Microbiol 294:363-71. 2004..Therefore, the combination of the hemolysin secretion system and S. typhi Ty21a could form the basis for a new generation of live bacterial vaccines...
Raf kinases in lung tumor developmentUlf R Rapp
, Strahlenkunde und Zellforschung (MSZ, , , Versbacher-Strasse 5, D-97078, , Germany
Adv Enzyme Regul 43:183-95. 2003
Use of a recombinant Salmonella enterica serovar Typhimurium strain expressing C-Raf for protection against C-Raf induced lung adenoma in miceIvaylo Gentschev
Institut für Medizinische Strahlenkunde und Zellforschung MSZ, University of Wuerzburg, D 97078 Wuerzburg, Germany
BMC Cancer 5:15. 2005..In this study we analyzed the functionality of a new live C-Raf vaccine based on an attenuated Salmonella enterica serovar Typhimurium aroA strain in two Raf dependent lung tumor mouse models...
Reactive antibodies against bacillus Calmette-Guerin heat-shock protein-65 potentially predict the outcome of immunotherapy for high-grade transitional cell carcinoma of the bladderPeter U Ardelt
Department of Urology and Pediatric Urology, Bavarian Julius Maximilians University Medical School, Wurzburg, Germany
Cancer 116:600-9. 2010..The objectives of this study were to identify a marker for measuring the BCG-induced immune response and to predict the outcomes and potential improvements of BCG immunotherapy...
Immunogenicity of constitutively active V599EBRafMads Hald Andersen
Insitute of Cancer Biology, Danish Cancer Society, Copenhagen, Denmark
Cancer Res 64:5456-60. 2004....
Vivotif--a 'magic shield' for protection against typhoid fever and delivery of heterologous antigensIvaylo Gentschev
Berna Biotech Ltd, Berne, Switzerland
Chemotherapy 53:177-80. 2007..Recently, we successfully used Ty21a for antigen delivery via the haemolysin secretion system of Escherichia coli, which allows efficient protein secretion from the carrier bacteria...
Regulatory CD4+CD25+ T cells restrict memory CD8+ T cell responsesMischo Kursar
Max Planck Institute for Infection Biology, Department of Immunology. Deutsches Rheumaforschungszentrum, Schumannstr. 21/22, 10117 Berlin, Germany
J Exp Med 196:1585-92. 2002..Down-modulation of CD8+ T cell responses during infection could prevent harmful consequences after eradication of the pathogen...
Cell-mediated immunity induced by recombinant Mycobacterium bovis Bacille Calmette-Guérin strains against an intracellular bacterial pathogen: importance of antigen secretion or membrane-targeted antigen display as lipoprotein for vaccine efficacyLeander Grode
Department of Immunology, Max-Planck-Institute for Infection Biology, Berlin, Germany
J Immunol 168:1869-76. 2002..monocytogenes challenge. Hence, differential Ag display by rBCG influences cell-mediated immunity, which in turn may impact vaccine efficacy due to the different requirements of CD4 or CD8 T cells for pathogen elimination...
