F J Conraths

Summary

Affiliation: Federal Research Centre for Virus Diseases of Animals
Country: Germany

Publications

  1. ncbi request reprint [Zoonoses in working- and wild animals and their significance in Germany. An overview]
    F J Conraths
    Bundesforschungsanstalt fur Viruskrankheiten der Tiere, Wusterhausen
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 47:633-46. 2004
  2. ncbi request reprint Expression of the microfilarial sheath protein 2 (shp2) of the filarial parasites Litomosoides sigmodontis and Brugia malayi
    F J Conraths
    Institut für Parasitologie, Justus Liebig Universitat Giessen, Germany
    Exp Parasitol 85:241-8. 1997
  3. ncbi request reprint Regional distribution of bovine Neospora caninum infection in the German state of Rhineland-Palatinate modelled by Logistic regression
    G Schares
    Institute of Epidemiology, Federal Research Centre for Virus Diseases of Animals, Seestrasse 55, D 16868 Wusterhausen, Germany
    Int J Parasitol 33:1631-40. 2003
  4. ncbi request reprint Eradication of Aujeszky's disease in Germany
    T Muller
    Institute of Epidemiological Diagnostics, Federal Research Centre for Virus Diseases of Animals, D 16868 Wusterhausen, Germany
    J Vet Med B Infect Dis Vet Public Health 50:207-13. 2003
  5. ncbi request reprint Cyclic transmission of Neospora caninum: serological findings in dogs shedding oocysts
    G Schares
    Institute for Epidemiological Diagnostics, Federal Research Centre for Virus Diseases of Animals, Wusterhausen, Germany
    Parasitol Res 87:873-7. 2001
  6. ncbi request reprint Hammondia heydorni-like oocysts shed by a naturally infected dog and Neospora caninum NC-1 cannot be distinguished
    G Schares
    Institute for Epidemiological Diagnostics, Federal Research Centre for Virus Diseases of Animals, Wusterhausen, Germany
    Parasitol Res 87:808-16. 2001
  7. ncbi request reprint Serological evidence for naturally occurring transmission of Neospora caninum among foxes (Vulpes vulpes)
    G Schares
    Institute for Epidemiological Diagnostics, Federal Research Centre for Virus Diseases of Animals, Seestrasse 55, D 16868 Wusterhausen, Germany
    Int J Parasitol 31:418-23. 2001
  8. ncbi request reprint Use of purified tachyzoite surface antigen p38 in an ELISA to diagnose bovine neosporosis
    G Schares
    Institute for Epidemiological Diagnostics, Federal Research Centre for Virus Diseases of Animals, Seestrasse 55, D 16868, Wusterhausen, Germany
    Int J Parasitol 30:1123-30. 2000
  9. ncbi request reprint [Control of Echinococcus multilocularis in Central Europe-- possibilities and limitations]
    K Tackmann
    Institut für epidemiologische Diagnostik, Bundesforschungsanstalt fur Viruskrankheiten der Tiere, Wusterhausen
    Berl Munch Tierarztl Wochenschr 113:139-43. 2000
  10. ncbi request reprint Neospora caninum: identification of 19-, 38-, and 40-kDa surface antigens and a 33-kDa dense granule antigen using monoclonal antibodies
    G Schares
    Institut für epidemiologische Diagnostik, Bundesforschungsanstalt fur Viruskrankheiten der Tiere, Seestrasse 55, Wusterhausen, D 16868, Germany
    Exp Parasitol 92:109-19. 1999

Collaborators

Detail Information

Publications39

  1. ncbi request reprint [Zoonoses in working- and wild animals and their significance in Germany. An overview]
    F J Conraths
    Bundesforschungsanstalt fur Viruskrankheiten der Tiere, Wusterhausen
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 47:633-46. 2004
    ..Against this background, the current knowledge on important zoonoses transmitted from livestock and some wildlife animals to humans as well as the epidemiological situation in Germany with regard to these diseases is summarized...
  2. ncbi request reprint Expression of the microfilarial sheath protein 2 (shp2) of the filarial parasites Litomosoides sigmodontis and Brugia malayi
    F J Conraths
    Institut für Parasitologie, Justus Liebig Universitat Giessen, Germany
    Exp Parasitol 85:241-8. 1997
    ..In the sheath, it exists as a highly polymerized molecule cross-linked by cysteine formation and other covalent bonds, presumably epsilon-(gamma-glutamyl)-lysine links...
  3. ncbi request reprint Regional distribution of bovine Neospora caninum infection in the German state of Rhineland-Palatinate modelled by Logistic regression
    G Schares
    Institute of Epidemiology, Federal Research Centre for Virus Diseases of Animals, Seestrasse 55, D 16868 Wusterhausen, Germany
    Int J Parasitol 33:1631-40. 2003
    ....
  4. ncbi request reprint Eradication of Aujeszky's disease in Germany
    T Muller
    Institute of Epidemiological Diagnostics, Federal Research Centre for Virus Diseases of Animals, D 16868 Wusterhausen, Germany
    J Vet Med B Infect Dis Vet Public Health 50:207-13. 2003
    ..Recently, Germany has been declared as officially AD-free by the European Commission...
  5. ncbi request reprint Cyclic transmission of Neospora caninum: serological findings in dogs shedding oocysts
    G Schares
    Institute for Epidemiological Diagnostics, Federal Research Centre for Virus Diseases of Animals, Wusterhausen, Germany
    Parasitol Res 87:873-7. 2001
    ..Therefore, our study provides initial information on a 152 kDa tachyzoite antigen, which might be a suitable candidate to identify dogs with a history of shedding N. caninum oocysts...
  6. ncbi request reprint Hammondia heydorni-like oocysts shed by a naturally infected dog and Neospora caninum NC-1 cannot be distinguished
    G Schares
    Institute for Epidemiological Diagnostics, Federal Research Centre for Virus Diseases of Animals, Wusterhausen, Germany
    Parasitol Res 87:808-16. 2001
    ..caninum or other protozoan parasites that use dogs as final hosts and have an oocyst morphology resembling that of I. bigemina/I. heydorni/H. heydorni...
  7. ncbi request reprint Serological evidence for naturally occurring transmission of Neospora caninum among foxes (Vulpes vulpes)
    G Schares
    Institute for Epidemiological Diagnostics, Federal Research Centre for Virus Diseases of Animals, Seestrasse 55, D 16868 Wusterhausen, Germany
    Int J Parasitol 31:418-23. 2001
    ..This result provides the first evidence for the postnatal or vertical transmission of N. caninum among naturally seropositive foxes...
  8. ncbi request reprint Use of purified tachyzoite surface antigen p38 in an ELISA to diagnose bovine neosporosis
    G Schares
    Institute for Epidemiological Diagnostics, Federal Research Centre for Virus Diseases of Animals, Seestrasse 55, D 16868, Wusterhausen, Germany
    Int J Parasitol 30:1123-30. 2000
    ..It may thus be appropriate to apply different cut-offs in serological tests depending on the abortion pattern to be analysed...
  9. ncbi request reprint [Control of Echinococcus multilocularis in Central Europe-- possibilities and limitations]
    K Tackmann
    Institut für epidemiologische Diagnostik, Bundesforschungsanstalt fur Viruskrankheiten der Tiere, Wusterhausen
    Berl Munch Tierarztl Wochenschr 113:139-43. 2000
    ..Requirements concerning the surveillance of control measures are demonstrated and the limitations of the imaginable control strategies discussed...
  10. ncbi request reprint Neospora caninum: identification of 19-, 38-, and 40-kDa surface antigens and a 33-kDa dense granule antigen using monoclonal antibodies
    G Schares
    Institut für epidemiologische Diagnostik, Bundesforschungsanstalt fur Viruskrankheiten der Tiere, Seestrasse 55, Wusterhausen, D 16868, Germany
    Exp Parasitol 92:109-19. 1999
    ..Immunohistochemical analysis of infected tissue sections indicated that the 33-kDa dense granule antigen is present in both tachyzoites and bradyzoites, while the 38-kDa surface antigen from tachyzoites seems to be absent in bradyzoites...
  11. ncbi request reprint The efficiency of vertical transmission of Neospora caninum in dairy cattle analysed by serological techniques
    G Schares
    Institute for Epidemiological Diagnostics, Federal Research Centre for Virus Diseases of Animals, Wusterhausen, Germany
    Vet Parasitol 80:87-98. 1998
    ..The results of this study suggest that the N. caninum-infection can be maintained over several generations at a nearly constant prevalence level, apparently without a need for dispersion by an definitive host...
  12. ncbi request reprint A Hammondia-like parasite from the European fox (Vulpes vulpes) forms biologically viable tissue cysts in cell culture
    G Schares
    Institute for Epidemiological Diagnostics, Federal Research Centre for Virus Diseases of Animals, Seestrasse 55, D 16868, Wusterhausen, Germany
    Int J Parasitol 33:229-34. 2003
    ..Since in vitro cystogenesis of dog-derived Hammondia heydorni has not been observed yet, in vitro cyst formation might be one trait to separate fox-derived Hammondia sp. from H. heydorni on a species level...
  13. ncbi request reprint Bovine neosporosis: comparison of serological methods using outbreak sera from a dairy herd in New Zealand
    G Schares
    Institute for Epidemiological Diagnostics, Federal Research Centre for Virus Diseases of Animals, Wusterhausen, Germany
    Int J Parasitol 29:1659-67. 1999
    ..Discrepancies in positive-negative classification between the two commercial ELISAs and one of the in-house ELISAs were due mainly to differences in the cut-off selection...
  14. ncbi request reprint Comparison and standardisation of serological methods for the diagnosis of Neospora caninum infection in bovines
    D von Blumröder
    Federal Research Centre for Virus Diseases of Animals, Institute of Epidemiology, Seestrasse 55, D 16868 Wusterhausen, Germany
    Vet Parasitol 120:11-22. 2004
    ..This procedure allows a standardised interpretation of results obtained with different tests used in independent, parallel seroepidemiological studies...
  15. ncbi request reprint Adaptation of a commercial ELISA for the detection of antibodies against Neospora caninum in bovine milk
    G Schares
    Institute of Epidemiology, Federal Research Center for Virus, Diseases of Animals, Seestrasse 55, D 16868 Wusterhausen, Germany
    Vet Parasitol 120:55-63. 2004
    ..The milk-based commercial ELISA classified more aborting dams as positive than the serum-based ELISA with this cut-off. The milk ELISA may be a valuable tool to assess the herd status with regard to abortion caused by N. caninum...
  16. ncbi request reprint Potential risk factors for bovine Neospora caninum infection in Germany are not under the control of the farmers
    G Schares
    Institute of Epidemiology, Federal Research Centre for Virus Diseases of Animals, Seestrasse 55, 16868 Wusterhausen, Germany
    Parasitology 129:301-9. 2004
    ..In addition, it suggests that the risk a herd has to acquire N. caninum infections is also associated with factors related to the farm location, i.e. factors that are largely out of the control of farmers...
  17. ncbi request reprint Adaptation of a surface antigen-based ELISA for the detection of antibodies against Neospora caninum in bovine milk
    G Schares
    Institute of Epidemiology, Friedrich Loeffler Institut Federal Research Institute for Animal Health, Seestrasse 55, D 16868 Wusterhausen, Germany
    J Vet Med B Infect Dis Vet Public Health 52:45-8. 2005
    ..The optimized linear regression model had an adjusted R(2) of 0.8501...
  18. ncbi request reprint p38-avidity-ELISA: examination of herds experiencing epidemic or endemic Neospora caninum-associated bovine abortion
    G Schares
    Federal Research Centre for Virus Diseases of Animals, Institute for Epidemiological Diagnostics and Institute for Epidemiology, Seestrasse 55, D 16868, Wusterhausen, Germany
    Vet Parasitol 106:293-305. 2002
    ..e. the severity of the abortion epidemic). A possible explanation for this observation is that herds experiencing heavy abortion are sampled earlier after the onset of the epidemic than others that have a less severe abortion storm...
  19. ncbi request reprint Is it possible to orally vaccinate juvenile red foxes against rabies in spring campaigns?
    T Muller
    Federal Research Center for Virus Diseases of Animals, WHO Collaborating Center for Rabies Surveillance and Research, 16868 Wusterhausen, Germany
    J Wildl Dis 37:791-7. 2001
    ..This phenomenon should be useful in further enhancing the efficacy of oral vaccination in red foxes...
  20. ncbi request reprint Detection of specific antibodies to Neospora caninum and Toxoplasma gondii in naturally infected alpacas (Lama pacos), llamas (Lama glama) and vicunas (Lama vicugna) from Peru and Germany
    D Wolf
    Institute of Parasitology, Justus Liebig University Giessen, Rudolf Buchheim Strasse 2, D 35392 Giessen, Germany
    Vet Parasitol 130:81-7. 2005
    ..However, our results confirm natural infections with N. caninum and T. gondii in SAC. Whether these infections are linked to any disease, e.g. reproductive losses, has to be clarified in further studies...
  21. ncbi request reprint Neospora caninum infection in Greek dairy cattle herds detected by two antibody assays in individual milk samples
    S Sotiraki
    Veterinary Research Institute, National Agricultural Research Foundation, Ionia, 57008 Thessaloniki, Greece
    Vet Parasitol 152:79-84. 2008
    ..In conclusion, N. caninum infection is present among dairy cattle in Greece, deserving more studies to determine its contribution to abortion problems in Greek dairy herds...
  22. ncbi request reprint Oocysts of Neospora caninum, Hammondia heydorni, Toxoplasma gondii and Hammondia hammondi in faeces collected from dogs in Germany
    G Schares
    Institute of Epidemiology, Friedrich Loeffler Institut, Federal Research Institute for Animal Health, Seestrasse 55, 16868 Wusterhausen, Germany
    Int J Parasitol 35:1525-37. 2005
    ..06. It may thus be possible to develop criteria for a preliminary identification of N. caninum in dog faeces based on the oocyst morphology...
  23. ncbi request reprint Phylogenetic analyses of highly pathogenic avian influenza virus isolates from Germany in 2006 and 2007 suggest at least three separate introductions of H5N1 virus
    E Starick
    Institute of Diagnostic Virology, Friedrich Loeffler Institute, 17493 Greifswald Insel Riems, Germany
    Vet Microbiol 128:243-52. 2008
    ..The viruses detected in 2007 most likely represent another new incursion from an as yet unknown source...
  24. ncbi request reprint Potential risk factors associated with bovine spongiform encephalopathy in cattle from Schleswig-Holstein, Germany
    C Pottgiesser
    Institute for Epidemiology, Federal Research Institute for Animal Health, Friedrich Loeffler Institut, Wusterhausen, Germany
    J Vet Med B Infect Dis Vet Public Health 53:306-11. 2006
    ..The results obtained using the indirect standardization analysis were validated by multiple logistic regression. This study indicates that the feedborne path has been the principal route of transmission for the BSE agent in SH...
  25. ncbi request reprint Animal disease outbreak control: the use of crisis management tools
    K Kroschewski
    Friedrich Loeffler Institute, Federal Research Institute for Animal Health, Institute of Epidemiology, Seestrasse 55, 16868 Wusterhausen Dosse, Germany
    Rev Sci Tech 25:211-21. 2006
    ..In this paper, the authors describe the use of these tools on the basis of their experience and in relation to what we can do now and what we should opt for in the future...
  26. ncbi request reprint Neospora caninum IgG avidity tests: an interlaboratory comparison
    C Bjorkman
    Department of Clinical Sciences, Swedish University of Agricultural Sciences, SE 750 07 Uppsala, Sweden
    Vet Parasitol 140:273-80. 2006
    ..Our experience suggests that avidity tests are sometimes less robust than conventional ELISAs. Therefore, it is essential that they are carefully standardised and their performance continuously evaluated...
  27. ncbi request reprint Supranational comparison of Neospora caninum seroprevalences in cattle in Germany, The Netherlands, Spain and Sweden
    C J M Bartels
    Animal Health Service Ltd, P O Box 9, 7400 AA Deventer, The Netherlands
    Vet Parasitol 137:17-27. 2006
    ..caninum infection varied greatly within in Europe. Estimates of prevalence can be used to calculate the economic impact of N. caninum infection as well as to evaluate the effect of prevention and control strategies over time...
  28. ncbi request reprint An interlaboratory comparison of immunohistochemistry and PCR methods for detection of Neospora caninum in bovine foetal tissues
    C van Maanen
    Animal Health Service, P O Box 9, NL 7400 AA Deventer, The Netherlands
    Vet Parasitol 126:351-64. 2004
    ..e. single or nested) and diagnostic sensitivity. Consequently, an improvement of diagnostic performance of PCR might possibly be achieved by optimizing DNA extraction methods...
  29. ncbi request reprint Bovine neosporosis: immunoblot improves foetal serology
    P Söndgen
    Staatliches Veterinäruntersuchungsamt, Zur Taubeneiche 10 12, D 59821, Arnsberg, Germany
    Vet Parasitol 102:279-90. 2001
    ..However, also the specificity of the IB was superior to that of the IFAT in relation to histology/immunohistochemistry, maternal serology and PCR...
  30. ncbi request reprint Geographic information system-aided analysis of factors associated with the spatial distribution of Echinococcus multilocularis infections of foxes
    C Staubach
    , , Wusterhausen, Germany
    Am J Trop Med Hyg 65:943-8. 2001
    ..multilocularis oncospheres. Thus open landscapes with humid soil seem to be favorable for the life cycle of the parasite. In contrast, infected foxes were significantly underrepresented in forest areas...
  31. pmc A field study to control Echinococcus multilocularis-infections of the red fox (Vulpes vulpes) in an endemic focus
    K Tackmann
    Federal Research Centre for Virus Diseases in Animals, Institute for Epidemiological Diagnostics, Wusterhausen, Germany
    Epidemiol Infect 127:577-87. 2001
    ..The effect was more pronounced in adult than in juvenile foxes. Under control conditions, the risk area decreased in size. However, an eradication of the parasite was not reached with the chosen strategy...
  32. ncbi request reprint An outbreak of enzootic bovine leukosis in upper Egypt: clinical, laboratory and molecular-epidemiological studies
    A Zaghawa
    Department of Animal Medicine and Infections and Fish Disease, Faculty of Veterinary Medicine, Menoufia University, Sadat City, Egypt
    J Vet Med B Infect Dis Vet Public Health 49:123-9. 2002
    ..Since this was the first recorded case of enzootic bovine leukosis in Upper Egypt, strict quarantine measures were adopted and all serologically positive animals in the herd were culled...
  33. ncbi request reprint Experimental infection of European wild boars and domestic pigs with pseudorabies viruses with differing virulence
    T F Müller
    Institute for Epidemiological Diagnostics, Federal Research Centre for Virus Diseases of Animals, Wusterhausen, Germany
    Am J Vet Res 62:252-8. 2001
    ..To determine susceptibility of European wild boars (Sus scrofa) to infection with pseudorabies virus (PrV) and to characterize the virulence of a wildboar PrV isolate for wild and domestic pigs...
  34. doi request reprint Occurrence of Toxoplasma gondii and Hammondia hammondi oocysts in the faeces of cats from Germany and other European countries
    G Schares
    Friedrich Loeffler Institut, Federal Research Institute for Animal Health, Institute of Epidemiology, Seestrasse 55, D 16868 Wusterhausen, Germany
    Vet Parasitol 152:34-45. 2008
    ..A PCR-RFLP analysis for the SAG2, SAG3, GRA6 and BTUB genes revealed T. gondii genotype II in all cases. Morphologically, H. hammondi oocysts exhibited a statistically significantly smaller Length-Width-Ratio than T. gondii oocysts...
  35. pmc A new Puumala hantavirus subtype in rodents associated with an outbreak of Nephropathia epidemica in South-East Germany in 2004
    S Essbauer
    Bundeswehr Institute of Microbiology, Munich, Germany
    Epidemiol Infect 134:1333-44. 2006
    ..PUUV sequences from bank voles in Lower Bavaria represent a new PUUV subtype which seems to be responsible for the observed increase of human hantavirus infections in 2004-2005...
  36. ncbi request reprint A virological survey in migrating waders and other waterfowl in one of the most important resting sites of Germany
    A Hlinak
    State Laboratory Brandenburg, Frankfurt Oder, D 15236 Frankfurt Oder, Germany
    J Vet Med B Infect Dis Vet Public Health 53:105-10. 2006
    ..These results confirm that the restricted resting sites in Western Europe must be considered as important locations for the intra- and interspecies transmission of avian viruses...
  37. pmc A long-term study on the prevalence of shiga toxin-producing Escherichia coli (STEC) on four German cattle farms
    L Geue
    Bundesforschungsanstalt fur Viruskrankheiten der Tiere, Institut für epidemiologische Diagnostik, Wusterhausen, Germany
    Epidemiol Infect 129:173-85. 2002
    ..Most STEC O26:H11 with the complete pattern of potential virulence markers were found in clinically healthy cattle. These animals may represent a risk factor for farmers and consumers...
  38. ncbi request reprint Detection of Echinococcus multilocularis in foxes: evaluation of a protocol of the intestinal scraping technique
    K Tackmann
    Friedrich Loeffler Institut, Federal Research Institute for Animal Health, Institute of Epidemiology, Seestr 55, 16868 Wusterhausen, Germany
    J Vet Med B Infect Dis Vet Public Health 53:395-8. 2006
    ..By contrast, a reduction of the number of slides examined per infected animal may lead to a considerable loss in sensitivity in animals with a low intensity of infection...
  39. pmc Neospora caninum microneme protein NcMIC3: secretion, subcellular localization, and functional involvement in host cell interaction
    A Naguleswaran
    Institute of Parasitology, University of Berne, CH-3012 Bern, Switzerland
    Infect Immun 69:6483-94. 2001
    ..Our data are indicative of a functional role of NcMIC3 in host cell infection...