- Highway or byway: the metabolic role of the GABA shunt in plantsAaron Fait
Department Willmitzer, Max Planck Institut fur Molekulare Pflanzenphysiologie, Am Muhlenberg 1, 14476 Potsdam Golm, Germany
Trends Plant Sci 13:14-9. 2008..We further evaluate technological developments that will likely allow us to address the quantitative importance of this shunt within the biological processes to which it contributes...
- Network analysis: tackling complex data to study plant metabolismDavid Toubiana
Max Planck Institut fur Molekulare Pflanzenphysiologie, Am Muhlenberg 1, 14476 Potsdam Golm, Germany
Trends Biotechnol 31:29-36. 2013..The relationship between structural and biological roles of network components can be evaluated and employed to aid metabolic engineering...
- Reduced expression of succinyl-coenzyme A ligase can be compensated for by up-regulation of the gamma-aminobutyrate shunt in illuminated tomato leavesClaudia Studart-Guimaraes
Department Willmitzer, Max Planck Institut fur Molekulare Pflanzenphysiologie, 14476 Golm, Germany
Plant Physiol 145:626-39. 2007..The results are discussed in the context of current models of plant respiration in mitochondrial and cellular metabolism of the illuminated leaf...
- Reconfiguration of the achene and receptacle metabolic networks during strawberry fruit developmentAaron Fait
Abteilung Willmitzer, Max Planck Institut fur Molekulare Pflanzenphysiologie, Potsdam Golm, Germany
Plant Physiol 148:730-50. 2008..The data are discussed within the context of current models both of the interaction of primary and secondary metabolism and of the metabolic interaction between the different plant organs...
- Mitochondrial succinic-semialdehyde dehydrogenase of the gamma-aminobutyrate shunt is required to restrict levels of reactive oxygen intermediates in plantsNicolas Bouche
School of Biology, University of Leeds, United Kingdom
Proc Natl Acad Sci U S A 100:6843-8. 2003..Our work establishes a role for the GABA shunt in preventing the accumulation of reactive oxygen intermediates and cell death, which appears to be essential for plant defense against environmental stress...
- The root-specific glutamate decarboxylase (GAD1) is essential for sustaining GABA levels in ArabidopsisNicolas Bouche
Commissariat a l Energie Atomique, Direction des Sciences du Vivant, Service de Bioenergetique, Gif sur Yvette, France
Plant Mol Biol 55:315-25. 2004..Our results show that the root-specific calcium/calmodulin-regulated GAD1 plays a major role in GABA synthesis in plants under normal growth conditions and in response to stress...
- GABA shunt deficiencies and accumulation of reactive oxygen intermediates: insight from Arabidopsis mutantsAaron Fait
Department of Plant Sciences, Weizmann Institute of Science, 76100 Rehovot, Israel
FEBS Lett 579:415-20. 2005..These results provide novel evidence for the relationship between the GABA shunt and ROI, which may, in part, explain the phenotype of SSADH-deficient plants and animals...
- The COMATOSE ATP-binding cassette transporter is required for full fertility in ArabidopsisSteven Footitt
Crop Performance and Improvement Division, Rothamsted Research, Harpenden, Hertfordshire, UK
Plant Physiol 144:1467-80. 2007..Taken together, our data support an important role for beta-oxidation in fertility in Arabidopsis (Arabidopsis thaliana) and suggest that this pathway could play a role in the mobilization of lipids in both pollen and female tissues...
- Increasing amino acid supply in pea embryos reveals specific interactions of N and C metabolism, and highlights the importance of mitochondrial metabolismKathleen Weigelt
Leibniz Institut für Pflanzengenetik und Kulturpflanzenforschung, Gatersleben, Germany
Plant J 55:909-26. 2008..These results demonstrate that legume seeds have a high capacity to regulate N:C ratios, and highlight the importance of mitochondria in the control of N-C balance and amino acid homeostasis...