Hideki Yokoyama

Summary

Affiliation: European Molecular Biology Laboratory
Country: Germany

Publications

  1. ncbi ISWI is a RanGTP-dependent MAP required for chromosome segregation
    Hideki Yokoyama
    European Molecular Biology Laboratory, Heidelberg 69117, Germany
    J Cell Biol 187:813-29. 2009
  2. ncbi Cdk11 is a RanGTP-dependent microtubule stabilization factor that regulates spindle assembly rate
    Hideki Yokoyama
    European Molecular Biology Laboratory, Heidelberg 69117, Germany
    J Cell Biol 180:867-75. 2008
  3. ncbi Hepatoma up-regulated protein is required for chromatin-induced microtubule assembly independently of TPX2
    Claudia M Casanova
    European Molecular Biology Laboratory, 69117 Heidelberg, Germany
    Mol Biol Cell 19:4900-8. 2008
  4. ncbi Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells
    Oliver J Gruss
    EMBL, Meyerhofstrasse 1, 69 117 Heidelberg, Germany
    Nat Cell Biol 4:871-9. 2002
  5. ncbi Activation of the innate immunity in Drosophila by endogenous chromosomal DNA that escaped apoptotic degradation
    Naomi Mukae
    Department of Genetics, Osaka University Medical School, Osaka 565 0871, Japan
    Genes Dev 16:2662-71. 2002

Collaborators

Detail Information

Publications5

  1. ncbi ISWI is a RanGTP-dependent MAP required for chromosome segregation
    Hideki Yokoyama
    European Molecular Biology Laboratory, Heidelberg 69117, Germany
    J Cell Biol 187:813-29. 2009
    ..Our results demonstrate that distinctly from its role in spindle assembly, RanGTP maintains spindle MTs in anaphase through the local activation of ISWI and that this is essential for proper chromosome segregation...
  2. ncbi Cdk11 is a RanGTP-dependent microtubule stabilization factor that regulates spindle assembly rate
    Hideki Yokoyama
    European Molecular Biology Laboratory, Heidelberg 69117, Germany
    J Cell Biol 180:867-75. 2008
    ..Our results indicate that Cdk11 is responsible for RanGTP-dependent MT stabilization around chromosomes and that this local stabilization is essential for normal rates of spindle assembly and spindle function...
  3. ncbi Hepatoma up-regulated protein is required for chromatin-induced microtubule assembly independently of TPX2
    Claudia M Casanova
    European Molecular Biology Laboratory, 69117 Heidelberg, Germany
    Mol Biol Cell 19:4900-8. 2008
    ..Our data indicate that HURP and TPX2 have nonredundant functions essential for chromatin-induced microtubule assembly...
  4. ncbi Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells
    Oliver J Gruss
    EMBL, Meyerhofstrasse 1, 69 117 Heidelberg, Germany
    Nat Cell Biol 4:871-9. 2002
    ..This indicates that chromosome-induced microtubule production is a general requirement for the formation of functional spindles in animal cells...
  5. ncbi Activation of the innate immunity in Drosophila by endogenous chromosomal DNA that escaped apoptotic degradation
    Naomi Mukae
    Department of Genetics, Osaka University Medical School, Osaka 565 0871, Japan
    Genes Dev 16:2662-71. 2002
    ..These results indicated that CAD and DNase II work independently to degrade chromosomal DNA during apoptosis, and if the DNA is left undigested, it can activate the innate immunity in Drosophila...