Hideki Yokoyama

Summary

Affiliation: European Molecular Biology Laboratory
Country: Germany

Publications

  1. pmc ISWI is a RanGTP-dependent MAP required for chromosome segregation
    Hideki Yokoyama
    European Molecular Biology Laboratory, Heidelberg 69117, Germany
    J Cell Biol 187:813-29. 2009
  2. doi request reprint CHD4 is a RanGTP-dependent MAP that stabilizes microtubules and regulates bipolar spindle formation
    Hideki Yokoyama
    European Molecular Biology Laboratory, Meyerhofstrasse 1, Heidelberg 69117, Germany Electronic address
    Curr Biol 23:2443-51. 2013
  3. pmc Cdk11 is a RanGTP-dependent microtubule stabilization factor that regulates spindle assembly rate
    Hideki Yokoyama
    European Molecular Biology Laboratory, Heidelberg 69117, Germany
    J Cell Biol 180:867-75. 2008
  4. pmc Hepatoma up-regulated protein is required for chromatin-induced microtubule assembly independently of TPX2
    Claudia M Casanova
    European Molecular Biology Laboratory, 69117 Heidelberg, Germany
    Mol Biol Cell 19:4900-8. 2008
  5. ncbi request reprint Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells
    Oliver J Gruss
    EMBL, Meyerhofstrasse 1, 69 117 Heidelberg, Germany
    Nat Cell Biol 4:871-9. 2002
  6. ncbi request reprint The nucleoporin MEL-28 promotes RanGTP-dependent γ-tubulin recruitment and microtubule nucleation in mitotic spindle formation
    Hideki Yokoyama
    1 Zentrum für Molekulare Biologie der Universität Heidelberg ZMBH, DKFZ ZMBH Alliance, Im Neuenheimer Feld 282, 69120 Heidelberg, Germany 2 European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany
    Nat Commun 5:3270. 2014
  7. pmc Activation of the innate immunity in Drosophila by endogenous chromosomal DNA that escaped apoptotic degradation
    Naomi Mukae
    Department of Genetics, Osaka University Medical School, Osaka 565 0871, Japan
    Genes Dev 16:2662-71. 2002

Collaborators

Detail Information

Publications7

  1. pmc ISWI is a RanGTP-dependent MAP required for chromosome segregation
    Hideki Yokoyama
    European Molecular Biology Laboratory, Heidelberg 69117, Germany
    J Cell Biol 187:813-29. 2009
    ..Our results demonstrate that distinctly from its role in spindle assembly, RanGTP maintains spindle MTs in anaphase through the local activation of ISWI and that this is essential for proper chromosome segregation...
  2. doi request reprint CHD4 is a RanGTP-dependent MAP that stabilizes microtubules and regulates bipolar spindle formation
    Hideki Yokoyama
    European Molecular Biology Laboratory, Meyerhofstrasse 1, Heidelberg 69117, Germany Electronic address
    Curr Biol 23:2443-51. 2013
    ..Several NLS proteins have been identified as spindle assembly factors, but the complexity of the process led us to search for additional proteins with distinct roles in spindle assembly...
  3. pmc Cdk11 is a RanGTP-dependent microtubule stabilization factor that regulates spindle assembly rate
    Hideki Yokoyama
    European Molecular Biology Laboratory, Heidelberg 69117, Germany
    J Cell Biol 180:867-75. 2008
    ..Our results indicate that Cdk11 is responsible for RanGTP-dependent MT stabilization around chromosomes and that this local stabilization is essential for normal rates of spindle assembly and spindle function...
  4. pmc Hepatoma up-regulated protein is required for chromatin-induced microtubule assembly independently of TPX2
    Claudia M Casanova
    European Molecular Biology Laboratory, 69117 Heidelberg, Germany
    Mol Biol Cell 19:4900-8. 2008
    ..Our data indicate that HURP and TPX2 have nonredundant functions essential for chromatin-induced microtubule assembly...
  5. ncbi request reprint Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells
    Oliver J Gruss
    EMBL, Meyerhofstrasse 1, 69 117 Heidelberg, Germany
    Nat Cell Biol 4:871-9. 2002
    ..This indicates that chromosome-induced microtubule production is a general requirement for the formation of functional spindles in animal cells...
  6. ncbi request reprint The nucleoporin MEL-28 promotes RanGTP-dependent γ-tubulin recruitment and microtubule nucleation in mitotic spindle formation
    Hideki Yokoyama
    1 Zentrum für Molekulare Biologie der Universität Heidelberg ZMBH, DKFZ ZMBH Alliance, Im Neuenheimer Feld 282, 69120 Heidelberg, Germany 2 European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany
    Nat Commun 5:3270. 2014
    ..Its cell cycle-dependent binding to chromatin or microtubules discriminates MEL-28 functions in interphase and mitosis, and ensures that spindle assembly occurs only after NPC breakdown. ..
  7. pmc Activation of the innate immunity in Drosophila by endogenous chromosomal DNA that escaped apoptotic degradation
    Naomi Mukae
    Department of Genetics, Osaka University Medical School, Osaka 565 0871, Japan
    Genes Dev 16:2662-71. 2002
    ..These results indicated that CAD and DNase II work independently to degrade chromosomal DNA during apoptosis, and if the DNA is left undigested, it can activate the innate immunity in Drosophila...