Affiliation: European Molecular Biology Laboratory
- Automatic identification and clustering of chromosome phenotypes in a genome wide RNAi screen by time-lapse imagingThomas Walter
European Molecular Biology Laboratory EMBL, Meyerhofstrasse 1, D 69117 Heidelberg, Germany
J Struct Biol 170:1-9. 2010..We demonstrate the use of these methods applying them on a genome wide RNAi screen by time-lapse microscopy...
- Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genesBeate Neumann
MitoCheck Project Group, European Molecular Biology Laboratory EMBL, Meyerhofstrasse 1, D 69117 Heidelberg, Germany
Nature 464:721-7. 2010..As part of the Mitocheck consortium, this study provides an in-depth analysis of cell division phenotypes and makes the entire high-content data set available as a resource to the community...
- Reverse transfection on cell arrays for high content screening microscopyHolger Erfle
MitoCheck Project Group, EMBL, Meyerhofstrasse 1, D 69117 Heidelberg, Germany
Nat Protoc 2:392-9. 2007..Different human cell lines that have been successfully transfected using the protocol are presented here. The present protocol has been applied to two genome-wide siRNA screens addressing mitosis and constitutive protein secretion...