Research Topics
Species | Katharina RibbeckSummaryAffiliation: European Molecular Biology Laboratory Country: Germany Publications
| Collaborators
|
Detail Information
Publications
Crm1 is a mitotic effector of Ran-GTP in somatic cellsAlexei Arnaoutov
Laboratory of Gene Regulation and Development, NICHD, NIH, Building 18, Room 106, Bethesda, MD 20892 5431, USA
Nat Cell Biol 7:626-32. 2005..Thus, Crm1 is a critical Ran-GTP effector for mitotic spindle assembly and function in somatic cells...
NuSAP, a mitotic RanGTP target that stabilizes and cross-links microtubulesKatharina Ribbeck
European Molecular Biology Laboratory, D 69117 Heidelberg, Germany
Mol Biol Cell 17:2646-60. 2006..Once activated, NuSAP may aid to maintain spindle integrity by stabilizing and cross-linking microtubules around chromatin...
A role for NuSAP in linking microtubules to mitotic chromosomesKatharina Ribbeck
European Molecular Biology Laboratory, Meyerhofstrasse 1, D 69117 Heidelberg, Germany
Curr Biol 17:230-6. 2007..We propose that the presence of MT binding agents such as NuSAP, which can be directly immobilized on chromatin, are critical for targeting MT production to vertebrate chromosomes during spindle self-organization...
Self-organization of anastral spindles by synergy of dynamic instability, autocatalytic microtubule production, and a spatial signaling gradientThomas Clausen
European Molecular Biology Laboratory, Heidelberg, Germany
PLoS ONE 2:e244. 2007..The mechanism proposed here can generate and maintain a dissipative MT super-structure within a RanGTP gradient...
Meiotic spindle: sculpted by severingKatharina Ribbeck
Systems Biology, Harvard Medical School, Boston, Massachusetts 02115, USA
Curr Biol 16:R923-5. 2006..A recent study using electron tomography has found that katanin stimulates the production of microtubules in the meiotic spindles of Caenorhabditis elegans oocytes...
The permeability barrier of nuclear pore complexes appears to operate via hydrophobic exclusionKatharina Ribbeck
ZMBH, INF 282, D-69120 Heidelberg, Germany
EMBO J 21:2664-71. 2002....
Characterization of Ran-driven cargo transport and the RanGTPase system by kinetic measurements and computer simulationDirk Gorlich
ZMBH, INF 282, 69120 Heidelberg, Germany
EMBO J 22:1088-100. 2003..This indicates that RanGTP gradients can provide positional information for mitotic spindle and NE assembly in early embryonic cells, but hardly any in small somatic cells...
NuSAP, a novel microtubule-associated protein involved in mitotic spindle organizationTim Raemaekers
Laboratory for Experimental Medicine and Endocrinology, Katholieke Universiteit Leuven, Leuven, Belgium
J Cell Biol 162:1017-29. 2003..In addition, many NuSAP-depleted interphase cells had deformed nuclei. Both overexpression and knockdown of NuSAP impaired cell proliferation. These results suggest a crucial role for NuSAP in spindle microtubule organization...
