Philipp J Keller

Summary

Affiliation: European Molecular Biology Laboratory
Country: Germany

Publications

  1. ncbi request reprint Life sciences require the third dimension
    Philipp J Keller
    EMBL Heidelberg, Cell Biology and Biophysics Unit, Meyerhofstrasse 1, D 69117 Heidelberg, Germany
    Curr Opin Cell Biol 18:117-24. 2006
  2. ncbi request reprint Three-dimensional preparation and imaging reveal intrinsic microtubule properties
    Philipp J Keller
    Cell Biology and Biophysics Unit, European Molecular Biology Laboratory EMBL, Meyerhofstrasse 1, D 69117 Heidelberg, Germany
    Nat Methods 4:843-6. 2007
  3. pmc Three-dimensional microtubule behavior in Xenopus egg extracts reveals four dynamic states and state-dependent elastic properties
    Philipp J Keller
    Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, Heidelberg, Germany
    Biophys J 95:1474-86. 2008
  4. doi request reprint Reconstruction of zebrafish early embryonic development by scanned light sheet microscopy
    Philipp J Keller
    Cell Biology and Biophysics Unit, European Molecular Biology Laboratory EMBL, Meyerhofstrasse 1, D 69117 Heidelberg, Germany
    Science 322:1065-9. 2008
  5. doi request reprint Quantitative in vivo imaging of entire embryos with Digital Scanned Laser Light Sheet Fluorescence Microscopy
    Philipp J Keller
    Cell Biology and Biophysics Unit, European Molecular Biology Laboratory EMBL, Heidelberg, Germany
    Curr Opin Neurobiol 18:624-32. 2008
  6. doi request reprint Fast, high-contrast imaging of animal development with scanned light sheet-based structured-illumination microscopy
    Philipp J Keller
    Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, Heidelberg, Germany
    Nat Methods 7:637-42. 2010
  7. doi request reprint Nlcam modulates midline convergence during anterior neural plate morphogenesis
    Katherine E Brown
    Developmental Biology, European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany
    Dev Biol 339:14-25. 2010

Collaborators

Detail Information

Publications7

  1. ncbi request reprint Life sciences require the third dimension
    Philipp J Keller
    EMBL Heidelberg, Cell Biology and Biophysics Unit, Meyerhofstrasse 1, D 69117 Heidelberg, Germany
    Curr Opin Cell Biol 18:117-24. 2006
    ..Our experience leads us to suggest that three-dimensional approaches reveal new aspects of a system and enable experiments to be performed in a more physiological and hence clinically more relevant context...
  2. ncbi request reprint Three-dimensional preparation and imaging reveal intrinsic microtubule properties
    Philipp J Keller
    Cell Biology and Biophysics Unit, European Molecular Biology Laboratory EMBL, Meyerhofstrasse 1, D 69117 Heidelberg, Germany
    Nat Methods 4:843-6. 2007
    ..Our approach gives experimental access to the intrinsic dynamic properties of microtubules and to microtubule population statistics in single asters. We obtain evidence for a stochastic nature of microtubule pausing...
  3. pmc Three-dimensional microtubule behavior in Xenopus egg extracts reveals four dynamic states and state-dependent elastic properties
    Philipp J Keller
    Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, Heidelberg, Germany
    Biophys J 95:1474-86. 2008
    ..These data might hint toward mechanisms that enable microtubules to efficiently perform multiple different tasks in the cell and suggest the development of a unified model of microtubule dynamics and microtubule mechanics...
  4. doi request reprint Reconstruction of zebrafish early embryonic development by scanned light sheet microscopy
    Philipp J Keller
    Cell Biology and Biophysics Unit, European Molecular Biology Laboratory EMBL, Meyerhofstrasse 1, D 69117 Heidelberg, Germany
    Science 322:1065-9. 2008
    ..We further derive a model of germ layer formation and show that the mesendoderm forms from one-third of the embryo's cells in a single event. Our digital embryos, with 55 million nucleus entries, are provided as a resource...
  5. doi request reprint Quantitative in vivo imaging of entire embryos with Digital Scanned Laser Light Sheet Fluorescence Microscopy
    Philipp J Keller
    Cell Biology and Biophysics Unit, European Molecular Biology Laboratory EMBL, Heidelberg, Germany
    Curr Opin Neurobiol 18:624-32. 2008
    ..We conclude with a perspective for future development...
  6. doi request reprint Fast, high-contrast imaging of animal development with scanned light sheet-based structured-illumination microscopy
    Philipp J Keller
    Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, Heidelberg, Germany
    Nat Methods 7:637-42. 2010
    ..We reconstructed cell positions over time from the Drosophila DSLM-SI data and created a fly digital embryo...
  7. doi request reprint Nlcam modulates midline convergence during anterior neural plate morphogenesis
    Katherine E Brown
    Developmental Biology, European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany
    Dev Biol 339:14-25. 2010
    ....