Gaspar Jekely

Summary

Affiliation: European Molecular Biology Laboratory
Country: Germany

Publications

  1. ncbi request reprint Origin of eukaryotic endomembranes: a critical evaluation of different model scenarios
    Gaspar Jekely
    European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany
    Adv Exp Med Biol 607:38-51. 2007
  2. ncbi request reprint Evolution of intraflagellar transport from coated vesicles and autogenous origin of the eukaryotic cilium
    Gaspar Jekely
    European Molecular Biology Laboratory, Heidelberg, Germany
    Bioessays 28:191-8. 2006
  3. ncbi request reprint Glimpsing over the event horizon: evolution of nuclear pores and envelope
    Gaspar Jekely
    Cell Cycle 4:297-9. 2005
  4. ncbi request reprint Cellular resolution expression profiling using confocal detection of NBT/BCIP precipitate by reflection microscopy
    Gaspar Jekely
    Developmental Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany
    Biotechniques 42:751-5. 2007
  5. ncbi request reprint Regulators of endocytosis maintain localized receptor tyrosine kinase signaling in guided migration
    Gaspar Jekely
    Developmental Biology Program, European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany
    Dev Cell 9:197-207. 2005
  6. pmc The evolution of nervous system centralization
    Detlev Arendt
    Developmental Biology Unit, European Molecular Biology Laboratory, Heidelberg 69117, Germany
    Philos Trans R Soc Lond B Biol Sci 363:1523-8. 2008
  7. doi request reprint Mechanism of phototaxis in marine zooplankton
    Gaspar Jekely
    Developmental Biology Unit, European Molecular Biology Laboratory, Heidelberg 69117, Germany
    Nature 456:395-9. 2008
  8. ncbi request reprint Small GTPases and the evolution of the eukaryotic cell
    Gaspar Jekely
    European Molecular Biology Laboratory, Developmental Biology, Meyerhofstrasse 1, 69117 Heidelberg, Germany
    Bioessays 25:1129-38. 2003
  9. pmc Wnt6 is required for maxillary palp formation in Drosophila
    Nikolaos Doumpas
    German Cancer Research Center DKFZ, Heidelberg, Germany
    BMC Biol 11:104. 2013
  10. pmc Evolution in a nutshell. EMBL PhD student symposium on evolution
    Gaspar Jekely
    European Molecular Biology Laboratory, Meyerhofstrasse 1, D 69117 Heidelberg, Germany
    EMBO Rep 3:307-11. 2002

Detail Information

Publications14

  1. ncbi request reprint Origin of eukaryotic endomembranes: a critical evaluation of different model scenarios
    Gaspar Jekely
    European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany
    Adv Exp Med Biol 607:38-51. 2007
    ..I argue that such models can best satisfy the major constraints of membrane topology, membrane heredity and straightforwardly account for selection pressures while being consistent with genomic findings...
  2. ncbi request reprint Evolution of intraflagellar transport from coated vesicles and autogenous origin of the eukaryotic cilium
    Gaspar Jekely
    European Molecular Biology Laboratory, Heidelberg, Germany
    Bioessays 28:191-8. 2006
    ..We propose a scenario for how the initial membrane patch gradually protruded to enhance exposure to the environment, then started to move, and finally compartmentalised to render receptor signalling and ciliary beating more efficient...
  3. ncbi request reprint Glimpsing over the event horizon: evolution of nuclear pores and envelope
    Gaspar Jekely
    Cell Cycle 4:297-9. 2005
    ..These analyses allow us to refine theories on the origin and evolution of the nucleus, and consequently, of the eukaryotic cell...
  4. ncbi request reprint Cellular resolution expression profiling using confocal detection of NBT/BCIP precipitate by reflection microscopy
    Gaspar Jekely
    Developmental Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany
    Biotechniques 42:751-5. 2007
    ..Whole-mount reflection CLSM will thus greatly facilitate large-scale cellular resolution expression profiling in vertebrate and invertebrate model organisms...
  5. ncbi request reprint Regulators of endocytosis maintain localized receptor tyrosine kinase signaling in guided migration
    Gaspar Jekely
    Developmental Biology Program, European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany
    Dev Cell 9:197-207. 2005
    ..Cbl and Sprint both regulate early steps of RTK endocytosis. Thus, a physiological role of RTK endocytosis is to ensure localized intracellular response to guidance cues by stimulating spatial restriction of signaling...
  6. pmc The evolution of nervous system centralization
    Detlev Arendt
    Developmental Biology Unit, European Molecular Biology Laboratory, Heidelberg 69117, Germany
    Philos Trans R Soc Lond B Biol Sci 363:1523-8. 2008
    ..This way, different aspects of the molecular architecture of the urbilaterian nervous system are reconstructed and yield insight into the degree of centralization that was in place in the bilaterian ancestors...
  7. doi request reprint Mechanism of phototaxis in marine zooplankton
    Gaspar Jekely
    Developmental Biology Unit, European Molecular Biology Laboratory, Heidelberg 69117, Germany
    Nature 456:395-9. 2008
    ..We propose that the underlying direct coupling of light sensing and ciliary locomotor control was a principal feature of the proto-eye and an important landmark in the evolution of animal eyes...
  8. ncbi request reprint Small GTPases and the evolution of the eukaryotic cell
    Gaspar Jekely
    European Molecular Biology Laboratory, Developmental Biology, Meyerhofstrasse 1, 69117 Heidelberg, Germany
    Bioessays 25:1129-38. 2003
    ..Based on the reconstruction of putative roles for ancestral small GTPases, a hypothetical scenario on the origins of the first endomembranes, the nucleus, and phagocytosis is presented...
  9. pmc Wnt6 is required for maxillary palp formation in Drosophila
    Nikolaos Doumpas
    German Cancer Research Center DKFZ, Heidelberg, Germany
    BMC Biol 11:104. 2013
    ..To test whether Wnt6 also contributes towards wing size regulation, we generated Wnt6 knockout flies...
  10. pmc Evolution in a nutshell. EMBL PhD student symposium on evolution
    Gaspar Jekely
    European Molecular Biology Laboratory, Meyerhofstrasse 1, D 69117 Heidelberg, Germany
    EMBO Rep 3:307-11. 2002
  11. pmc Hrs mediates downregulation of multiple signalling receptors in Drosophila
    Gaspar Jekely
    European Molecular Biology Laboratory, Developmental Biology Program, Heidelberg, Germany
    EMBO Rep 4:1163-8. 2003
    ..Finally, most hrs-dependent receptor turnover appears to be ligand independent. Thus, both active and inactive signalling receptors are targeted for degradation in vivo and Hrs is required for their removal...
  12. ncbi request reprint Molecular architecture of annelid nerve cord supports common origin of nervous system centralization in bilateria
    Alexandru S Denes
    Developmental Biology Unit, European Molecular Biology Laboratory, Heidelberg, 69117, Germany
    Cell 129:277-88. 2007
    ..Our data indicate that this mediolateral architecture was present in the last common bilaterian ancestor and thus support a common origin of nervous system centralization in Bilateria...