Claudia Chica

Summary

Affiliation: European Molecular Biology Laboratory
Country: Germany

Publications

  1. pmc Evidence for the concerted evolution between short linear protein motifs and their flanking regions
    Claudia Chica
    Structural and Computational Biology Unit, EMBL Heidelberg, Heidelberg, Germany
    PLoS ONE 4:e6052. 2009
  2. pmc ELM: the status of the 2010 eukaryotic linear motif resource
    Cathryn M Gould
    Structural and Computational Biology Unit, European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany
    Nucleic Acids Res 38:D167-80. 2010
  3. pmc Phospho.ELM: a database of phosphorylation sites--update 2011
    Holger Dinkel
    SCB Unit, EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany
    Nucleic Acids Res 39:D261-7. 2011
  4. pmc KEPE--a motif frequently superimposed on sumoylation sites in metazoan chromatin proteins and transcription factors
    Francesca Diella
    Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany
    Bioinformatics 25:1-5. 2009
  5. ncbi request reprint Understanding eukaryotic linear motifs and their role in cell signaling and regulation
    Francesca Diella
    Structural and Computational Biology Unit, European Molecular Biology Laboratory, 69117 Heidelberg, Germany
    Front Biosci 13:6580-603. 2008
  6. pmc ELM--the database of eukaryotic linear motifs
    Holger Dinkel
    Structural and Computational Biology, European Molecular Biology Laboratory, Heidelberg, Germany
    Nucleic Acids Res 40:D242-51. 2012
  7. pmc Phospho.ELM: a database of phosphorylation sites--update 2008
    Francesca Diella
    Structural and Computational Biology Unit, European Molecular Biology Laboratory, 69117 Heidelberg, Germany
    Nucleic Acids Res 36:D240-4. 2008
  8. doi request reprint Discovery of candidate KEN-box motifs using cell cycle keyword enrichment combined with native disorder prediction and motif conservation
    Sushama Michael
    Structural and Computational Biology Unit, EMBL, Meyerhofstrasse 1, D 69117, Heidelberg, Germany
    Bioinformatics 24:453-7. 2008

Collaborators

Detail Information

Publications8

  1. pmc Evidence for the concerted evolution between short linear protein motifs and their flanking regions
    Claudia Chica
    Structural and Computational Biology Unit, EMBL Heidelberg, Heidelberg, Germany
    PLoS ONE 4:e6052. 2009
    ..Sometimes linear motifs appear as isolated islands of conservation in multiple sequence alignments. However, they also occur in larger blocks of sequence conservation, suggesting an active role for the neighbouring amino acids...
  2. pmc ELM: the status of the 2010 eukaryotic linear motif resource
    Cathryn M Gould
    Structural and Computational Biology Unit, European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany
    Nucleic Acids Res 38:D167-80. 2010
    ..Using the links, researchers can explore the motifs, proteins, complex structures and associated literature to evaluate whether candidate motifs might be worth experimental investigation...
  3. pmc Phospho.ELM: a database of phosphorylation sites--update 2011
    Holger Dinkel
    SCB Unit, EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany
    Nucleic Acids Res 39:D261-7. 2011
    ..Finally, special emphasis has been put on linking to external resources such as interaction networks and other databases...
  4. pmc KEPE--a motif frequently superimposed on sumoylation sites in metazoan chromatin proteins and transcription factors
    Francesca Diella
    Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany
    Bioinformatics 25:1-5. 2009
    ..We noted that the sumoylation site in C/EBP homologues is conserved beyond the canonical consensus sequence for sumoylation. Therefore, we investigated whether this pattern might define a more general protein motif...
  5. ncbi request reprint Understanding eukaryotic linear motifs and their role in cell signaling and regulation
    Francesca Diella
    Structural and Computational Biology Unit, European Molecular Biology Laboratory, 69117 Heidelberg, Germany
    Front Biosci 13:6580-603. 2008
    ..The discrete deterministic properties implicit to these assemblies suggest that models for cell regulatory networks in systems biology should neither be overly dependent on stochastic nor on smooth deterministic approximations...
  6. pmc ELM--the database of eukaryotic linear motifs
    Holger Dinkel
    Structural and Computational Biology, European Molecular Biology Laboratory, Heidelberg, Germany
    Nucleic Acids Res 40:D242-51. 2012
    ..The motif discovery portion of the ELM resource has added conservation, and structural attributes have been incorporated to aid users to discriminate biologically relevant motifs from stochastically occurring non-functional instances...
  7. pmc Phospho.ELM: a database of phosphorylation sites--update 2008
    Francesca Diella
    Structural and Computational Biology Unit, European Molecular Biology Laboratory, 69117 Heidelberg, Germany
    Nucleic Acids Res 36:D240-4. 2008
    ..Phospho.ELM is available on line at: http://phospho.elm.eu.org...
  8. doi request reprint Discovery of candidate KEN-box motifs using cell cycle keyword enrichment combined with native disorder prediction and motif conservation
    Sushama Michael
    Structural and Computational Biology Unit, EMBL, Meyerhofstrasse 1, D 69117, Heidelberg, Germany
    Bioinformatics 24:453-7. 2008
    ..A similar number of weaker candidates were present. These proteins have yet to be tested for APC/C targeted destruction, providing potential new avenues of research...