Claudia Chica

Summary

Affiliation: European Molecular Biology Laboratory
Country: Germany

Publications

  1. pmc A new protein linear motif benchmark for multiple sequence alignment software
    Emmanuel Perrodou
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, Department of Structural Biology and Genomics, F 67400 Illkirch, France
    BMC Bioinformatics 9:213. 2008
  2. pmc A tree-based conservation scoring method for short linear motifs in multiple alignments of protein sequences
    Claudia Chica
    EMBL Structural and Computational Biology Unit, Meyerhofstrasse 1, 69117 Heidelberg, Germany
    BMC Bioinformatics 9:229. 2008
  3. pmc ELM: the status of the 2010 eukaryotic linear motif resource
    Cathryn M Gould
    Structural and Computational Biology Unit, European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany
    Nucleic Acids Res 38:D167-80. 2010
  4. pmc Phospho.ELM: a database of phosphorylation sites--update 2011
    Holger Dinkel
    SCB Unit, EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany
    Nucleic Acids Res 39:D261-7. 2011
  5. ncbi request reprint Understanding eukaryotic linear motifs and their role in cell signaling and regulation
    Francesca Diella
    Structural and Computational Biology Unit, European Molecular Biology Laboratory, 69117 Heidelberg, Germany
    Front Biosci 13:6580-603. 2008
  6. pmc Evidence for the concerted evolution between short linear protein motifs and their flanking regions
    Claudia Chica
    Structural and Computational Biology Unit, EMBL Heidelberg, Heidelberg, Germany
    PLoS ONE 4:e6052. 2009
  7. pmc Phospho.ELM: a database of phosphorylation sites--update 2008
    Francesca Diella
    Structural and Computational Biology Unit, European Molecular Biology Laboratory, 69117 Heidelberg, Germany
    Nucleic Acids Res 36:D240-4. 2008
  8. doi request reprint Discovery of candidate KEN-box motifs using cell cycle keyword enrichment combined with native disorder prediction and motif conservation
    Sushama Michael
    Structural and Computational Biology Unit, EMBL, Meyerhofstrasse 1, D 69117, Heidelberg, Germany
    Bioinformatics 24:453-7. 2008

Collaborators

Detail Information

Publications8

  1. pmc A new protein linear motif benchmark for multiple sequence alignment software
    Emmanuel Perrodou
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, Department of Structural Biology and Genomics, F 67400 Illkirch, France
    BMC Bioinformatics 9:213. 2008
    ..As a consequence, poor motif alignment quality is hindering efforts to detect new LMs...
  2. pmc A tree-based conservation scoring method for short linear motifs in multiple alignments of protein sequences
    Claudia Chica
    EMBL Structural and Computational Biology Unit, Meyerhofstrasse 1, 69117 Heidelberg, Germany
    BMC Bioinformatics 9:229. 2008
    ..It is therefore desirable to efficiently predict linear motifs with some degree of accuracy, yet sequence database searches return results that are not significant...
  3. pmc ELM: the status of the 2010 eukaryotic linear motif resource
    Cathryn M Gould
    Structural and Computational Biology Unit, European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany
    Nucleic Acids Res 38:D167-80. 2010
    ..Using the links, researchers can explore the motifs, proteins, complex structures and associated literature to evaluate whether candidate motifs might be worth experimental investigation...
  4. pmc Phospho.ELM: a database of phosphorylation sites--update 2011
    Holger Dinkel
    SCB Unit, EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany
    Nucleic Acids Res 39:D261-7. 2011
    ..Finally, special emphasis has been put on linking to external resources such as interaction networks and other databases...
  5. ncbi request reprint Understanding eukaryotic linear motifs and their role in cell signaling and regulation
    Francesca Diella
    Structural and Computational Biology Unit, European Molecular Biology Laboratory, 69117 Heidelberg, Germany
    Front Biosci 13:6580-603. 2008
    ..The discrete deterministic properties implicit to these assemblies suggest that models for cell regulatory networks in systems biology should neither be overly dependent on stochastic nor on smooth deterministic approximations...
  6. pmc Evidence for the concerted evolution between short linear protein motifs and their flanking regions
    Claudia Chica
    Structural and Computational Biology Unit, EMBL Heidelberg, Heidelberg, Germany
    PLoS ONE 4:e6052. 2009
    ..Sometimes linear motifs appear as isolated islands of conservation in multiple sequence alignments. However, they also occur in larger blocks of sequence conservation, suggesting an active role for the neighbouring amino acids...
  7. pmc Phospho.ELM: a database of phosphorylation sites--update 2008
    Francesca Diella
    Structural and Computational Biology Unit, European Molecular Biology Laboratory, 69117 Heidelberg, Germany
    Nucleic Acids Res 36:D240-4. 2008
    ..Phospho.ELM is available on line at: http://phospho.elm.eu.org...
  8. doi request reprint Discovery of candidate KEN-box motifs using cell cycle keyword enrichment combined with native disorder prediction and motif conservation
    Sushama Michael
    Structural and Computational Biology Unit, EMBL, Meyerhofstrasse 1, D 69117, Heidelberg, Germany
    Bioinformatics 24:453-7. 2008
    ..eu.org/), we found that KEN motifs were significantly enriched in human protein entries with cell cycle keywords in the UniProt/Swiss-Prot database-implying that KEN-boxes might be more common than reported...