Research Topics | Peer BorkSummaryAffiliation: European Molecular Biology Laboratory Country: Germany Publications
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Publications
STITCH 3: zooming in on protein-chemical interactionsMichael Kuhn
Biotechnology Center, TU Dresden, 01062 Dresden, Germany
Nucleic Acids Res 40:D876-80. 2012..Combining the isomers increases the coverage, as interaction databases and publications found through text mining will often refer to compounds without specifying the stereoisomer. The database is accessible at http://stitch.embl.de/...
Prediction of effective genome size in metagenomic samplesJeroen Raes
European Molecular Biology Laboratory, Meyerhofstrasse 1, D 69117 Heidelberg, Germany
Genome Biol 8:R10. 2007..7 Mb; for bacteria in a nutrient-poor, organism-sparse ocean surface water sample, EGS is as low as 1.6 Mb. The method also permits evaluation of completion status and assembly bias in single-genome sequencing projects...
High-resolution transcription atlas of the mitotic cell cycle in budding yeastMarina V Granovskaia
EMBL European Molecular Biology Laboratory, Department of Genome Biology, Meyerhofstr, Heidelberg, Germany
Genome Biol 11:R24. 2010..To explore the complex transcriptome architecture underlying the budding yeast cell cycle, we used 8 bp tiling arrays to generate a 5 minute-resolution, strand-specific expression atlas of the whole genome...
Selective maintenance of Drosophila tandemly arranged duplicated genes during evolutionCarlos Quijano
Instituto de Investigaciones Biomedicas CSIC UAM, Arturo Duperier 4, 28029 Madrid, Spain
Genome Biol 9:R176. 2008..However, the contribution of gene duplication to gene order has not been analyzed in detail, as it is believed that co-expression due to recent duplicates would obscure other domains of co-expression...
Circular reasoning rather than cyclic expressionLars Juhl Jensen
Genome Biol 9:403. 2008..A response to Combined analysis reveals a core set of cycling genes by Y Lu, S Mahony, PV Benos, R Rosenfeld, I Simon, LL Breeden and Z Bar-Joseph. Genome Biol 2007, 8:R146...
Large gene overlaps in prokaryotic genomes: result of functional constraints or mispredictions?Albert Pallejà
Biochemistry and Biotechnology Department, Rovira i Virgili University, C Marcel li Domingo s n, 43007 Tarragona, Catalunya, Spain
BMC Genomics 9:335. 2008..Here we examine the longest overlaps and assess whether they are the product of special functional constraints or of erroneous annotation...
Non-random retention of protein-coding overlapping genes in MetazoaGiulia Soldà
1Department of Biology and Genetics for Medical Sciences, University of Milan, 20133 Milan, Italy
BMC Genomics 9:174. 2008..Here we report a comparative analysis of overlaps between genes coding for well-annotated proteins in five metazoan genomes (human, mouse, zebrafish, fruit fly and worm)...
G2D: a tool for mining genes associated with diseaseCarolina Perez-Iratxeta
Ontario Genomics Innovation Centre, Ottawa Health Research Institute, ON K1H 8L6, Ottawa, Canada
BMC Genet 6:45. 2005..We previously developed an algorithm to prioritize genes on a chromosomal region according to their possible relation to an inherited disease using a combination of data mining on biomedical databases and gene sequence analysis...
DCD - a novel plant specific domain in proteins involved in development and programmed cell deathRaimund Tenhaken
Plant Molecular Biology, University of Frankfurt, Marie Curie Str, 9, 60439 Frankfurt, Germany
BMC Bioinformatics 6:169. 2005..We delineate the NRP-gene in soybean, which is specifically induced during this programmed cell death and contains a novel protein domain, which is commonly found in different plant proteins...
Information extraction from full text scientific articles: where are the keywords?Parantu K Shah
Biocomputing, European Molecular Biology Laboratory, Heidelberg, Germany
BMC Bioinformatics 4:20. 2003..Several questions arise as to whether the effort of scanning full text articles is worthy, or whether the information that can be extracted from the different sections of an article can be relevant...
STITCH 2: an interaction network database for small molecules and proteinsMichael Kuhn
Biotechnology Center, TU Dresden, 01062 Dresden, Germany
Nucleic Acids Res 38:D552-6. 2010..STITCH 2.0 connects proteins from 630 organisms to over 74,000 different chemicals, including 2200 drugs. STITCH can be accessed at http://stitch.embl.de/...
STRING v9.1: protein-protein interaction networks, with increased coverage and integrationAndrea Franceschini
Institute of Molecular Life Sciences and Swiss Institute of Bioinformatics, University of Zurich, Switzerland
Nucleic Acids Res 41:D808-15. 2013....
