P I Bastiaens
Affiliation: European Molecular Biology Laboratory
- Observing proteins in their natural habitat: the living cellP I Bastiaens
EMBL Heidelberg, Meyerhofstr 1, 69117 Heidelberg, Germany
Trends Biochem Sci 25:631-7. 2000..This possibility will not only play an important role in the understanding of biochemical reactions in signal processing and fidelity but also help to uncover the molecular mechanisms of organelle and cell morphogenesis...
- Lateral phosphorylation propagation: an aspect of feedback signalling?Christian Tischer
European Molecular Biology Laboratory, Heidelberg, Germany
Nat Rev Mol Cell Biol 4:971-4. 2003
- Imaging biochemistry inside cellsF S Wouters
Cell Biology and Cell Biophysics Program, European Molecular Biology Laboratory, Meyerhofstrasse 1, D-69117, Heidelberg, Germany
Trends Cell Biol 11:203-11. 2001..Protein activities and interactions can be imaged and localized within a single cell, allowing correlation with phenomena such as the cell cycle, migration and morphogenesis...
- Improved spatial discrimination of protein reaction states in cells by global analysis and deconvolution of fluorescence lifetime imaging microscopy dataP J Verveer
Cell Biology and Cell Biophysics Program, European Molecular Biology Laboratory, Meyerhofstrasse 1, D-69117 Heidelberg, Germany
J Microsc 202:451-6. 2001..We applied these techniques to quantitatively image the phosphorylation state of ErbB1 receptors tagged with green fluorescent protein in MCF7 cells...