Research Topics
Species | Miguel A AndradeSummaryAffiliation: European Molecular Biology Laboratory Country: Germany Publications
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Detail Information
Publications
NEAT: a domain duplicated in genes near the components of a putative Fe3+ siderophore transporter from Gram-positive pathogenic bacteriaMiguel A Andrade
European Molecular Biology Laboratory, Meyerhofstr, 1, 69117 Heidelberg, Germany
Genome Biol 3:RESEARCH0047. 2002..To find potential targets for drugs active against pathogenic bacteria, we have searched all completely sequenced genomes of pathogenic bacteria for genes relevant for iron transport...- Systematic association of genes to phenotypes by genome and literature miningJan O Korbel
European Molecular Biology Laboratory, Heidelberg, Germany
PLoS Biol 3:e134. 2005..Among the clusters, we observe an enrichment of pathogenicity-related associations, suggesting that the approach reveals many novel genes likely to play a role in infectious diseases... 
A protocol for the update of references to scientific literature in biological databasesCarolina Perez-Iratxeta
European Molecular Biology Laboratory, Heidelberg, Germany
Appl Bioinformatics 2:189-91. 2003..Human experts found the references that the algorithm scored highly were more relevant to the database entry than those scored lowly, suggesting that the algorithm was useful...- Update on XplorMed: A web server for exploring scientific literatureCarolina Perez-Iratxeta
European Molecular Biology Laboratory, Meyerhofstr 1, 69117 Heidelberg, Germany
Nucleic Acids Res 31:3866-8. 2003..Here we describe new features added to XplorMed during the last 2 years (http://www.bork.embl-heidelberg.de/xplormed/)... - Global analysis of bacterial transcription factors to predict cellular target processesTobias Doerks
EMBL, 69117 Heidelberg, Meyerhofstr 1, Germany
Trends Genet 20:126-31. 2004.... - Information extraction from full text scientific articles: where are the keywords?Parantu K Shah
Biocomputing, European Molecular Biology Laboratory, Heidelberg, Germany
BMC Bioinformatics 4:20. 2003..Several questions arise as to whether the effort of scanning full text articles is worthy, or whether the information that can be extracted from the different sections of an article can be relevant... - Human Lsg1 defines a family of essential GTPases that correlates with the evolution of compartmentalizationEmmanuel G Reynaud
Cell Biology and Cell Biophysics Programme, European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany
BMC Biol 3:21. 2005..Therefore, they are ideal tools for comparative genomic studies aimed at understanding how aspects of biological complexity such as cellular compartmentalization evolved... - Exploring MEDLINE abstracts with XplorMedCarolina Perez-Iratxeta
European Molecular Biology Laboratory, Heidelberg, Germany
Drugs Today (Barc) 38:381-9. 2002..XplorMed is available http://www.bork. embl-heidelberg.de/xplormed... - Computing fuzzy associations for the analysis of biological literatureCarolina Perez-Iratxeta
European Molecular Biology Laboratory, Heidelberg, Germany
Biotechniques 32:1380-2, 1384-5. 2002..Those relations are used to derive ensembles of related words and their associated subsets of abstracts. The algorithm can be used publicly at http:// www.bork.embl-heidelberg.de/xplormed/... - Association of genes to genetically inherited diseases using data miningCarolina Perez-Iratxeta
European Molecular Biology Laboratory, Meyerhofstr.1, Heidelberg 69012, Germany
Nat Genet 31:316-9. 2002..The scoring also indicates that for some diseases, the chance of identifying the underlying gene is higher... - Evaluation of annotation strategies using an entire genome sequenceIoannis Iliopoulos
Computational Genomics Group, The European Bioinformatics Institute, EMBL Cambridge Outstation, Cambridge CB10 1SD, UK
Bioinformatics 19:717-26. 2003..The most surprising result of this comparative study is that automatic systems might perform as well as the teams of experts annotating genome sequences... - Ranking the whole MEDLINE database according to a large training set using text indexingBrian P Suomela
Ontario Genomics Innovation Centre, Ottawa Health Research Institute, 501 Smyth Rd, Ottawa, Ontario K1H 8L6, Canada
BMC Bioinformatics 6:75. 2005..This report describes a method that does this ranking using the differences in word content between MEDLINE entries related to a topic and the whole of MEDLINE, in a computational time appropriate for an article search query engine... - G2D: a tool for mining genes associated with diseaseCarolina Perez-Iratxeta
Ontario Genomics Innovation Centre, Ottawa Health Research Institute, ON K1H 8L6, Ottawa, Canada
BMC Genet 6:45. 2005..We previously developed an algorithm to prioritize genes on a chromosomal region according to their possible relation to an inherited disease using a combination of data mining on biomedical databases and gene sequence analysis... - The Shwachman-Bodian-Diamond syndrome protein family is involved in RNA metabolismAlexei Savchenko
Ontario Center for Structural Proteomics, University of Toronto, Canada
J Biol Chem 280:19213-20. 2005..Our observations, taken together with previous reports, support the conclusion that SBDS and its homologues play a role in RNA metabolism... - ACRATA: a novel electron transfer domain associated to apoptosis and cancerLuis Sanchez-Pulido
Protein Design Group, Centro Nacional de Biotecnologia CNB CSIC, Cantoblanco, Madrid, E 28049, Spain
BMC Cancer 4:98. 2004..g. STEAP, STAMP1, TSAP6), have been identified in Golgi and cytoplasmic membranes. The exact function of these proteins remains unknown... - Worldwide scientific publishing activityCarolina Perez-Iratxeta
Science 297:519. 2002 - Gene annotation from scientific literature using mappings between keyword systemsAntonio J Pérez
University of Malaga, Facultad de Ciencias, Departmento de Genetica, Group of Bioinformatics, Campus Universitario de Teatinos, 29071 Malaga, Spain
Bioinformatics 20:2084-91. 2004..However, the association of keywords to genes or protein sequences is a difficult process that ultimately implies examination of the literature related to a gene... - The way we writeRebecca Netzel
Institute of Translation and Interpreting, University of Heidelberg, Germany
EMBO Rep 4:446-51. 2003