Research Topics

Genomes and Genes


Meral Esen


Country: Germany


  1. Gabor J, Schwarz N, Esen M, Kremsner P, Grobusch M. Dengue and chikungunya seroprevalence in Gabonese infants prior to major outbreaks in 2007 and 2010: A sero-epidemiological study. Travel Med Infect Dis. 2016;14:26-31 pubmed publisher
    ..Clinical diagnosis of dengue and chikungunya is difficult especially in infants, underscoring the need for accurate and reliable diagnostic tests as well as awareness of medical personnel. NCT00167843. ..
  2. Esen M, Forster J, Ajua A, Spänkuch I, Paparoupa M, Mordmuller B, et al. Effect of IL-15 on IgG versus IgE antibody-secreting cells in vitro. J Immunol Methods. 2012;375:7-13 pubmed publisher
    ..We show that our method is suitable for the detection of specific and non-specific IgE-ASCs and IgG-ASCs and allows the investigation of the interplay between IgG-ASCs and IgE-ASCs in different populations. ..
  3. Mordmüller B, Supan C, Sim K, Gómez Pérez G, Ospina Salazar C, Held J, et al. Direct venous inoculation of Plasmodium falciparum sporozoites for controlled human malaria infection: a dose-finding trial in two centres. Malar J. 2015;14:117 pubmed publisher
    ..Beyond this, rational dose selection for whole PfSPZ-based immunization and complex study designs are now possible. NCT01624961 and NCT01771848 . ..
  4. Brückner S, Agnandji S, Elias J, Berberich S, Bache E, Fernandes J, et al. A single-dose antihelminthic treatment does not influence immunogenicity of a meningococcal and a cholera vaccine in Gabonese school children. Vaccine. 2016;34:5384-5390 pubmed publisher
    ..A single-dose treatment with albendazole prior to immunization had no effect on meningococcal or cholera vaccine immunogenicity in our study population. ..
  5. Gbédandé K, Fievet N, Viwami F, Ezinmegnon S, Issifou S, Chippaux J, et al. Clinical development of a VAR2CSA-based placental malaria vaccine PAMVAC: Quantifying vaccine antigen-specific memory B & T cell activity in Beninese primigravidae. Vaccine. 2017;35:3474-3481 pubmed publisher
    ..Women with a T helper cell profile biased towards production of Th2-type cytokines have a greater risk of infection with P. falciparum. ..