Martin Rudwaleit

Summary

Affiliation: Endokrinologikum Hamburg
Country: Germany

Publications

  1. ncbi request reprint Adalimumab for the treatment of ankylosing spondylitis and nonradiographic axial spondyloarthritis - a five-year update
    Denis Poddubnyy
    Endokrinologikum Berlin, Rheumatologie, Jägerstraße 61, Berlin, Germany
    Expert Opin Biol Ther 13:1599-611. 2013
  2. doi request reprint Referral strategies for early diagnosis of axial spondyloarthritis
    Martin Rudwaleit
    Endokrinologikum Berlin, Jägerstrasse 61, 10117 Berlin, Germany
    Nat Rev Rheumatol 8:262-8. 2012
  3. doi request reprint [Management of nonspecific low back pain. The new national guidelines 2011]
    M Rudwaleit
    Endokrinologikum Berlin, Jägerstr 61, 10117, Berlin, Deutschland
    Z Rheumatol 71:485-97; quiz 498-9. 2012
  4. doi request reprint Similar response rates in patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis after 1 year of treatment with etanercept: results from the ESTHER trial
    In Ho Song
    Department of Rheumatology, Charité Medical University, Berlin, Germany
    Ann Rheum Dis 72:823-5. 2013
  5. doi request reprint Baseline radiographic damage, elevated acute-phase reactant levels, and cigarette smoking status predict spinal radiographic progression in early axial spondylarthritis
    Denis Poddubnyy
    Charite Universitatsmedizin, Campus Benjamin Franklin, Berlin, Germany
    Arthritis Rheum 64:1388-98. 2012
  6. doi request reprint The early disease stage in axial spondylarthritis: results from the German Spondyloarthritis Inception Cohort
    Martin Rudwaleit
    Charité Medical University Hospital, Campus Benjamin Franklin, and German Rheumatism Research Centre, Berlin, Germany
    Arthritis Rheum 60:717-27. 2009
  7. doi request reprint Rates and predictors of radiographic sacroiliitis progression over 2 years in patients with axial spondyloarthritis
    Denis Poddubnyy
    Department of Rheumatology, Charite Campus Benjamin Franklin, Berlin, Germany
    Ann Rheum Dis 70:1369-74. 2011
  8. doi request reprint Active inflammation and structural change in early active axial spondyloarthritis as detected by whole-body MRI
    Christian E Althoff
    Department of Radiology, Charité Medical University, Campus Mitte, Berlin, Germany
    Ann Rheum Dis 72:967-73. 2013
  9. ncbi request reprint Adalimumab reduces spinal symptoms in active ankylosing spondylitis: clinical and magnetic resonance imaging results of a fifty-two-week open-label trial
    Hildrun Haibel
    Benjamin Franklin Hospital, Berlin, Germany
    Arthritis Rheum 54:678-81. 2006
  10. pmc Performance of referral recommendations in patients with chronic back pain and suspected axial spondyloarthritis
    Henning Christian Brandt
    Rheumatology, Department of Medicine I, Charite Campus Benjamin Franklin, Berlin, Germany
    Ann Rheum Dis 66:1479-84. 2007

Collaborators

Detail Information

Publications36

  1. ncbi request reprint Adalimumab for the treatment of ankylosing spondylitis and nonradiographic axial spondyloarthritis - a five-year update
    Denis Poddubnyy
    Endokrinologikum Berlin, Rheumatologie, Jägerstraße 61, Berlin, Germany
    Expert Opin Biol Ther 13:1599-611. 2013
    ..The increasing number of patients with AS being treated with adalimumab raises issues concerning long-term safety, efficacy in the prevention of structural damage in the spine and high treatment costs...
  2. doi request reprint Referral strategies for early diagnosis of axial spondyloarthritis
    Martin Rudwaleit
    Endokrinologikum Berlin, Jägerstrasse 61, 10117 Berlin, Germany
    Nat Rev Rheumatol 8:262-8. 2012
    ....
  3. doi request reprint [Management of nonspecific low back pain. The new national guidelines 2011]
    M Rudwaleit
    Endokrinologikum Berlin, Jägerstr 61, 10117, Berlin, Deutschland
    Z Rheumatol 71:485-97; quiz 498-9. 2012
    ....
  4. doi request reprint Similar response rates in patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis after 1 year of treatment with etanercept: results from the ESTHER trial
    In Ho Song
    Department of Rheumatology, Charité Medical University, Berlin, Germany
    Ann Rheum Dis 72:823-5. 2013
    ..We assessed whether there is a difference to etanercept (ETA) treatment in patients with ankylosing spondylitis (AS) compared with non-radiographic axial SpA (nr-axSpA) patients with a disease duration <5 years...
  5. doi request reprint Baseline radiographic damage, elevated acute-phase reactant levels, and cigarette smoking status predict spinal radiographic progression in early axial spondylarthritis
    Denis Poddubnyy
    Charite Universitatsmedizin, Campus Benjamin Franklin, Berlin, Germany
    Arthritis Rheum 64:1388-98. 2012
    ..To assess prospectively the rates and to explore predictors of spinal radiographic progression over 2 years in a cohort of patients with early axial spondylarthritis (SpA)...
  6. doi request reprint The early disease stage in axial spondylarthritis: results from the German Spondyloarthritis Inception Cohort
    Martin Rudwaleit
    Charité Medical University Hospital, Campus Benjamin Franklin, and German Rheumatism Research Centre, Berlin, Germany
    Arthritis Rheum 60:717-27. 2009
    ..Moreover, we sought to identify determinants of the development of radiographic sacroiliitis...
  7. doi request reprint Rates and predictors of radiographic sacroiliitis progression over 2 years in patients with axial spondyloarthritis
    Denis Poddubnyy
    Department of Rheumatology, Charite Campus Benjamin Franklin, Berlin, Germany
    Ann Rheum Dis 70:1369-74. 2011
    ..To assess the progression of radiographic sacroiliitis in a cohort of patients with early axial spondyloarthritis over a period of 2 years and to explore predictors of progression...
  8. doi request reprint Active inflammation and structural change in early active axial spondyloarthritis as detected by whole-body MRI
    Christian E Althoff
    Department of Radiology, Charité Medical University, Campus Mitte, Berlin, Germany
    Ann Rheum Dis 72:967-73. 2013
    ..To evaluate active inflammatory lesions (AIL) and structural changes (SC) in patients with active non-radiographic axial spondyloarthritis (nr-axSpA) compared with patients with ankylosing spondylitis (AS) on whole-body MRI (wb-MRI)...
  9. ncbi request reprint Adalimumab reduces spinal symptoms in active ankylosing spondylitis: clinical and magnetic resonance imaging results of a fifty-two-week open-label trial
    Hildrun Haibel
    Benjamin Franklin Hospital, Berlin, Germany
    Arthritis Rheum 54:678-81. 2006
  10. pmc Performance of referral recommendations in patients with chronic back pain and suspected axial spondyloarthritis
    Henning Christian Brandt
    Rheumatology, Department of Medicine I, Charite Campus Benjamin Franklin, Berlin, Germany
    Ann Rheum Dis 66:1479-84. 2007
    ..Referral parameters that are easy for doctors in primary care to apply to patients presenting with possible AS could contribute to earlier diagnosis...
  11. ncbi request reprint In vitro observations of T cell responsiveness to recall antigens during tumor necrosis factor-alpha-blocking therapy in patients with ankylosing spondylitis
    Heiner Appel
    Department of Gastroenterology, Infectiology and Rheumatology, Charite Berlin, Campus Benjamin Franklin, Hindenbergdamm 30, Berlin, Germany
    J Rheumatol 34:2264-70. 2007
    ..This raises the question if an alteration of T cell function can be detected by in vitro analysis to identify patients who might be more at risk of acquiring such infectious diseases...
  12. doi request reprint Altered skeletal expression of sclerostin and its link to radiographic progression in ankylosing spondylitis
    Heiner Appel
    Charite Berlin, Campus Benjamin Franklin, Berlin, Germany
    Arthritis Rheum 60:3257-62. 2009
    ..The contribution of osteocytes in regulating local bone remodeling in arthritis is unknown. The aim of this study was to investigate the role of osteocytes as contributors to bone remodeling in ankylosing spondylitis (AS)...
  13. doi request reprint Evaluation of 2 screening strategies for early identification of patients with axial spondyloarthritis in primary care
    Denis Poddubnyy
    Department of Rheumatology, Charite Campus Benjamin Franklin, Berlin, Germany
    J Rheumatol 38:2452-60. 2011
    ..To evaluate 2 referral strategies for axial spondyloarthritis (SpA) in patients with chronic low back pain at the primary care level...
  14. doi request reprint Efficacy of adalimumab in the treatment of axial spondylarthritis without radiographically defined sacroiliitis: results of a twelve-week randomized, double-blind, placebo-controlled trial followed by an open-label extension up to week fifty-two
    Hildrun Haibel
    Charité Medical University Hospital, Campus Benjamin Franklin, Berlin, Germany
    Arthritis Rheum 58:1981-91. 2008
    ..To evaluate the efficacy and safety of the tumor necrosis factor (TNF) antagonist adalimumab in patients with axial spondylarthritis (SpA) without radiographically defined sacroiliitis refractory to conventional treatment...
  15. doi request reprint Critical appraisal of assessment of structural damage in ankylosing spondylitis: implications for treatment outcomes
    Joachim Sieper
    Charite University Medicine Berlin, Campus Benjamin Franklin, Berlin, Germany
    Arthritis Rheum 58:649-56. 2008
  16. doi request reprint Frequency and duration of drug-free remission after 1 year of treatment with etanercept versus sulfasalazine in early axial spondyloarthritis: 2 year data of the ESTHER trial
    In Ho Song
    Department of Rheumatology, Charité Medical University, Campus Benjamin Franklin, Berlin, Germany
    Ann Rheum Dis 71:1212-5. 2012
    ....
  17. ncbi request reprint New onset of Crohn's disease during treatment of active ankylosing spondylitis with etanercept
    In Ho Song
    Department of Rheumatology, Division of Medicine, and Institute for Pathology Research Center ImmunoSciences RCIS, Charité Medical University, Campus Benjamin Franklin, Berlin, Germany
    J Rheumatol 35:532-6. 2008
    ..New onset of CD may be considered as an immune-mediated injury induced by etanercept. Although this is an intriguing hypothesis, any causative role of etanercept remains unproven at this stage...
  18. doi request reprint Adalimumab is effective and well tolerated in treating patients with ankylosing spondylitis who have advanced spinal fusion
    Martin Rudwaleit
    Medical Department I, Rheumatology, Charite, Campus Benjamin Franklin Hospital, Berlin, Germany
    Rheumatology (Oxford) 48:551-7. 2009
    ..To evaluate the effectiveness and safety of adalimumab in treating patients with AS and advanced structural damage...
  19. doi request reprint [Early diagnosis of ankylosing spondylitis and spondyolarthritis and predictors of outome]
    Martin Rudwaleit
    Rheumatologie, Medizinische Klinik I, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany
    Wien Med Wochenschr 158:186-90. 2008
    ..Male sex, extraspinal manifestations, and existing syndesmophytes on radiographs appear to be predictors of a worse disease outcome...
  20. ncbi request reprint Inflammatory back pain in ankylosing spondylitis: a reassessment of the clinical history for application as classification and diagnostic criteria
    Martin Rudwaleit
    Charite, Campus Benjamin Franklin, Berlin, Germany
    Arthritis Rheum 54:569-78. 2006
    ..In this exploratory study, we sought to evaluate the individual features of IBP and to compose and compare various combinations of features for use as classification and diagnostic criteria...
  21. doi request reprint From transcriptome to cytome: integrating cytometric profiling, multivariate cluster, and prediction analyses for a phenotypical classification of inflammatory diseases
    Marta Steinbrich-Zöllner
    German Arthritis Research Center DRFZ, Immune Monitoring Core, Berlin, Germany
    Cytometry A 73:333-40. 2008
    ..The integration of an appropriate bioinformatic solution as presented here by the combination of a custom-made Access database along with cluster- and prediction-analysis tools predestine our approach to promote the human cytome project...
  22. doi request reprint Evaluation of the spinal pain score in AS--a psychometric analysis
    In Ho Song
    Rheumatology Unit, Charité Medical University, Berlin, Germany
    Rheumatology (Oxford) 51:2155-63. 2012
    ..To evaluate the spinal pain score (SpiPS), a semi-objective instrument for measuring disease activity in AS...
  23. doi request reprint Descriptions of spinal MRI lesions and definition of a positive MRI of the spine in axial spondyloarthritis: a consensual approach by the ASAS/OMERACT MRI study group
    Kay Geert A Hermann
    Department of Radiology, Charite University Hospital, Berlin, Germany
    Ann Rheum Dis 71:1278-88. 2012
    ..The aim of this study was to define characteristic MRI findings in the spine of patients with axial spondyloarthritis (SpA) and provide a definition of a positive spinal MRI for inflammation and structural changes...
  24. ncbi request reprint Congenital absence of the portal vein with splenomegaly and hypersplenism in a young woman
    Heiner Appel
    Department of Gastroenterology and Rheumatology, University Hospital Benjamin Franklin, Berlin, Germany
    Digestion 67:105-10. 2003
    ..A CT scan revealed an empty liver hilus without portal vein. Here we discuss clinical aspects of this patient, show radiologic and histopathologic findings, and compare them to other cases in the literature...
  25. ncbi request reprint Whole-body magnetic resonance imaging evaluation of widespread inflammatory lesions in a patient with ankylosing spondylitis before and after 1 year of treatment with infliximab
    Heiner Appel
    Department of Gastroenterology, Infectiology and Rheumatology, Charite Berlin, Campus Benjamin Franklin, Berlin, Germany
    J Rheumatol 34:2497-8. 2007
  26. ncbi request reprint A case of axial undifferentiated spondyloarthritis diagnosis and management
    Martin Rudwaleit
    Rheumatology, Department of Medicine I, Charite Universitatsmedizin, Berlin, Germany
    Nat Clin Pract Rheumatol 3:298-303. 2007
    ..A 32-year-old white man presented with features of inflammatory back pain, including awakening at night and morning stiffness. He had acute back pain 4 years earlier as a result of a herniated lumbar disc...
  27. ncbi request reprint Immunohistologic analysis of zygapophyseal joints in patients with ankylosing spondylitis
    Heiner Appel
    Charite Berlin, Campus Benjamin Franklin, Berlin, Germany
    Arthritis Rheum 54:2845-51. 2006
    ..Zygapophyseal joints of the spine are often affected in ankylosing spondylitis (AS). In this study, we undertook a systematic immunohistologic evaluation of the immunopathology of the zygapophyseal joints in patients with advanced AS...
  28. ncbi request reprint The challenge of diagnosis and classification in early ankylosing spondylitis: do we need new criteria?
    Martin Rudwaleit
    Charite, Campus Benjamin Franklin, Berlin, Germany
    Arthritis Rheum 52:1000-8. 2005
  29. pmc Autoregulation of Th1-mediated inflammation by twist1
    Uwe Niesner
    German Rheumatism Research Center Berlin, 10117 Berlin, Germany
    J Exp Med 205:1889-901. 2008
    ....
  30. doi request reprint New approaches to diagnosis and classification of axial and peripheral spondyloarthritis
    Martin Rudwaleit
    Charite University Medicine Berlin, Campus Benjamin Franklin, Berlin, Germany
    Curr Opin Rheumatol 22:375-80. 2010
    ..The diagnostic delay in AS of several years is mainly attributable to the late appearance of definite sacroiliitis on radiographs. Efforts have been made in recent years to improve and standardize making an early diagnosis...
  31. doi request reprint Adalimumab improves sleep and sleep quality in patients with active ankylosing spondylitis
    Martin Rudwaleit
    Charite University, Benjamin Franklin Campus, Berlin, Germany
    J Rheumatol 38:79-86. 2011
    ..This subanalysis of the RHAPSODY study (Review of Safety and Effectiveness with Adalimumab in Patients with Active Ankylosing Spondylitis) was conducted to evaluate the effect of adalimumab on sleep in patients with active AS...
  32. doi request reprint Relevance of osteoproliferation as an outcome parameter in ankylosing spondylitis
    Heiner Appel
    Department of Medicine at the Charité Hospital Benjamin Franklin, Berlin, Germany
    Nat Clin Pract Rheumatol 4:578-9. 2008
    ..In this Viewpoint the authors explore the relevance of osteoproliferation amongst other outcome parameters...
  33. ncbi request reprint Down-regulation of the nonspecific and antigen-specific T cell cytokine response in ankylosing spondylitis during treatment with infliximab
    Jianxiang Zou
    Benjamin Franklin Klinikum, Deutsches Rheumaforschungszentrum, Berlin, Germany
    Arthritis Rheum 48:780-90. 2003
    ..This study was undertaken to investigate the precise mechanism of action of anti-TNF alpha treatment in AS...
  34. ncbi request reprint Massive splenomegaly and hypersplenism in a young woman with primary Sjögren's syndrome
    Heiner Appel
    Department of Gastroenterology and Rheumatology, Benjamin Franklin Medical Center, Berlin, Germany
    J Rheumatol 29:2012-3. 2002
  35. doi request reprint Certolizumab pegol in axial spondyloarthritis
    In Ho Song
    Charite Universitatsmedizin Berlin, Medical Clinic I Rheumatology, Berlin, Germany
    Expert Rev Clin Immunol 9:1161-72. 2013
    ..The interesting data of this important trial in the context of the emerging therapeutic field of non-radiographic axial SpA therapy is discussed in this review. ..
  36. ncbi request reprint Ankylosing spondylitis and bowel disease
    Martin Rudwaleit
    Rheumatology, Charite Campus Benjamin Franklin, Berlin, Germany
    Best Pract Res Clin Rheumatol 20:451-71. 2006
    ..Adalimumab appears to be effective in treating both AS and IBD; however, official approval is pending. Currently, infliximab is the drug of choice for the treatment of patients with active AS associated with IBD...