Paul Enck

Summary

Country: Germany

Publications

  1. pmc Sensitivity and specificity of hypnosis effects on gastric myoelectrical activity
    Paul Enck
    Department of Psychosomatic Medicine, University Hospital, Tubingen, Germany
    PLoS ONE 8:e83486. 2013
  2. pmc Effects of ginger and expectations on symptoms of nausea in a balanced placebo design
    Katja Weimer
    Department of Psychosomatic Medicine and Psychotherapy, University Hospital Tubingen, Tubingen, Germany
    PLoS ONE 7:e49031. 2012
  3. pmc Six-year follow-up of patients with functional bowel disorders, with and without previous psychotherapy
    Ute Martens
    University Medical Hospital, Dept of Psychosomatic Medicine and Psychotherapy, University of Tubingen, Germany
    Psychosoc Med 7:Doc06. 2010
  4. pmc Probiotic treatment of irritable bowel syndrome in children
    U Martens
    Department of Internal Medicine, Psychosomatic Medicine and Psychotherapy, University Hospital Tubingen, Germany
    Ger Med Sci 8:Doc07. 2010
  5. pmc Cholecystokinin revisited: CCK and the hunger trap in anorexia nervosa
    Ulrich Cuntz
    Klinik Roseneck Center for Behavioral Medicine, Prien, Germany
    PLoS ONE 8:e54457. 2013
  6. doi The placebo response in medicine: minimize, maximize or personalize?
    Paul Enck
    Department of Internal Medicine VI, University Hospital Tubingen, 72076 Tubingen, Germany
    Nat Rev Drug Discov 12:191-204. 2013
  7. doi The placebo response in clinical trials-the current state of play
    Paul Enck
    Department of Psychosomatic Medicine, University Hospital Tubingen, Germany
    Complement Ther Med 21:98-101. 2013
  8. doi Placebo responses and placebo effects in functional bowel disorders
    Paul Enck
    Department of Psychosomatic Medicine, University Hospital Tubingen, Frondsbergstrasse 23, Tubingen, Germany
    Eur J Gastroenterol Hepatol 24:1-8. 2012
  9. doi A novel placebo-controlled clinical study design without ethical concerns - the free choice paradigm
    Paul Enck
    Department of Psychosomatic Medicine, University Hospital Tubingen, Tubingen, Germany
    Med Hypotheses 79:880-2. 2012
  10. doi [Probiotic therapy of the irritable bowel syndrome]
    P Enck
    Klinik fur Psychosomatische Medizin und Psychotherapie, Universitatsklinikum Tubingen
    Dtsch Med Wochenschr 136:371-5. 2011

Detail Information

Publications95

  1. pmc Sensitivity and specificity of hypnosis effects on gastric myoelectrical activity
    Paul Enck
    Department of Psychosomatic Medicine, University Hospital, Tubingen, Germany
    PLoS ONE 8:e83486. 2013
    ..The effects of hypnosis on physiological (gastrointestinal) functions are incompletely understood, and it is unknown whether they are hypnosis-specific and gut-specific, or simply unspecific effects of relaxation...
  2. pmc Effects of ginger and expectations on symptoms of nausea in a balanced placebo design
    Katja Weimer
    Department of Psychosomatic Medicine and Psychotherapy, University Hospital Tubingen, Tubingen, Germany
    PLoS ONE 7:e49031. 2012
    ..The "balanced placebo design" has been proposed to allow better separation of drug and placebo effects...
  3. pmc Six-year follow-up of patients with functional bowel disorders, with and without previous psychotherapy
    Ute Martens
    University Medical Hospital, Dept of Psychosomatic Medicine and Psychotherapy, University of Tubingen, Germany
    Psychosoc Med 7:Doc06. 2010
    ..Discussion: Anxiety and depression may determine consulting behaviour, but this appears unrelated to intestinal symptoms and their severity. Short-term PT contributes to long-term well-being especially in men...
  4. pmc Probiotic treatment of irritable bowel syndrome in children
    U Martens
    Department of Internal Medicine, Psychosomatic Medicine and Psychotherapy, University Hospital Tubingen, Germany
    Ger Med Sci 8:Doc07. 2010
    ..5-4.5x10(7) CFU of bacteria of Escherichia coli type), in the elder children 77% received this dosage, while the remaining received a higher dose up to 30 drops/day. Treatment lasted 43 days on average...
  5. pmc Cholecystokinin revisited: CCK and the hunger trap in anorexia nervosa
    Ulrich Cuntz
    Klinik Roseneck Center for Behavioral Medicine, Prien, Germany
    PLoS ONE 8:e54457. 2013
    ..In this study a highly specific assay for the biologically active part of CCK was used in patients with bulimic as well as with the restricting type of AN who were followed over the course of weight gain...
  6. doi The placebo response in medicine: minimize, maximize or personalize?
    Paul Enck
    Department of Internal Medicine VI, University Hospital Tubingen, 72076 Tubingen, Germany
    Nat Rev Drug Discov 12:191-204. 2013
    ..Finally, personalizing placebo responses - which involves considering an individual's genetic predisposition, personality, past medical history and treatment experience - could also maximize therapeutic outcomes...
  7. doi The placebo response in clinical trials-the current state of play
    Paul Enck
    Department of Psychosomatic Medicine, University Hospital Tubingen, Germany
    Complement Ther Med 21:98-101. 2013
    ....
  8. doi Placebo responses and placebo effects in functional bowel disorders
    Paul Enck
    Department of Psychosomatic Medicine, University Hospital Tubingen, Frondsbergstrasse 23, Tubingen, Germany
    Eur J Gastroenterol Hepatol 24:1-8. 2012
    ..In this narrative review, different methodologies (meta-analyses, reanalyses, and experimental setups) are discussed that have been applied to the study of the placebo response in functional dyspepsia and the irritable bowel syndrome...
  9. doi A novel placebo-controlled clinical study design without ethical concerns - the free choice paradigm
    Paul Enck
    Department of Psychosomatic Medicine, University Hospital Tubingen, Tubingen, Germany
    Med Hypotheses 79:880-2. 2012
    ..Advantages as well as disadvantages and limitations of the FCP still need to be assessed, as need the computational statistics to demonstrate superiority of drug over placebo. Ethical limitations are, however, minimized...
  10. doi [Probiotic therapy of the irritable bowel syndrome]
    P Enck
    Klinik fur Psychosomatische Medizin und Psychotherapie, Universitatsklinikum Tubingen
    Dtsch Med Wochenschr 136:371-5. 2011
    ..In addition to the actual status of probiotic efficacy in IBS studies conducted worldwide, we present 3 German clinical studies with probiotic E.COLI preparations that have proven their efficacy in IBS in adults and in children...
  11. doi Randomized controlled treatment trial of irritable bowel syndrome with a probiotic E.-coli preparation (DSM17252) compared to placebo
    P Enck
    Internal Medicine VI, University Medical Hospital, Tubingen, Germany
    Z Gastroenterol 47:209-14. 2009
    ..Therapy trials with bacterial compounds in irritable bowel syndrome (IBS) have produced conflicting results and, so far, an E.-coli preparation has not been used...
  12. doi Circadian variation of rectal sensitivity and gastrointestinal peptides in healthy volunteers
    P Enck
    Medical Department VI, University Hospital Tubingen, Tubingen, Germany
    Neurogastroenterol Motil 21:52-8. 2009
    ..This circadian variation needs to be taken into account in patients and volunteer studies...
  13. doi New insights into the placebo and nocebo responses
    Paul Enck
    Department of Internal Medicine VI Psychosomatic Medicine and Psychotherapy, University Hospital, 72076 Tubingen, Germany
    Neuron 59:195-206. 2008
    ....
  14. doi A mixture of Escherichia coli (DSM 17252) and Enterococcus faecalis (DSM 16440) for treatment of the irritable bowel syndrome--a randomized controlled trial with primary care physicians
    P Enck
    Department of Internal Medicine VI, University Hospital of Tubingen, Tubingen, Germany
    Neurogastroenterol Motil 20:1103-9. 2008
    ..0001). Treatment of IBS with the bacterial lysate ProSymbioflor is effective and superior to placebo in reducing typical symptoms of IBS patients seen by general practitioners...
  15. doi [The next consensus for the irritable bowel syndrome has to be interdisciplinary]
    P Enck
    Psychosomatic Medicine, University Hospitals Tubingen, Tubingen
    Z Gastroenterol 46:211-5. 2008
    ....
  16. doi The effects of ageing on the colonic bacterial microflora in adults
    P Enck
    Psychosomatic Medicine and Psychotherapy, University Hospital Tubingen, Frondsbergstr 23, 72076 Tubingen
    Z Gastroenterol 47:653-8. 2009
    ..The composition of the fecal mircoflora and its changes on ageing have rarely been investigated in large samples of both patients and volunteers...
  17. ncbi The psyche and the gut
    Paul Enck
    University Hospitals Tubingen, Department of Internal Medicine VI, Psychosomatic Medicine and Psychotherapy, Osianderstrasse 5, Tubingen 72076, Germany
    World J Gastroenterol 13:3405-8. 2007
    ..Increasing focus underlines the importance of enhancing our understanding on how the psyche and the brain communicate in order to better meet the needs of our patients...
  18. ncbi Internet-based assessment of bowel symptoms and quality of life
    Paul Enck
    Department of Psychosomatic Medicine and Psychotherapy, University Hospitals Tubingen, Tubingen Germany
    Eur J Gastroenterol Hepatol 18:1263-9. 2006
    ..We wished to determine the value of an open-access internet questionnaire for assessment of upper and lower gastrointestinal symptoms and health-related quality of life...
  19. doi The placebo response in functional dyspepsia--reanalysis of trial data
    P Enck
    University Hospital, Department of Psychosomatic Medicine, Tubingen, Germany
    Neurogastroenterol Motil 21:370-7. 2009
    ..Variables predicting the PR point towards behavioural and biological mechanism of the PR, operating simultaneously and independently...
  20. doi The story of O--is oxytocin the mediator of the placebo response?
    P Enck
    Department of Internal Medicine VI Psychosomatic Medicine and Psychotherapy, University Hospital, Tubingen, Germany
    Neurogastroenterol Motil 21:347-50. 2009
    ....
  21. doi Therapy options in irritable bowel syndrome
    Paul Enck
    Department of Internal Medicine VI, University Hospital, Tubingen, Germany
    Eur J Gastroenterol Hepatol 22:1402-11. 2010
    ..By large, this should enable physicians to select from a number of therapy options available...
  22. pmc The placebo response in clinical trials: more questions than answers
    Paul Enck
    Department of Internal Medicine VI Psychosomatic Medicine and Psychotherapy, University Hospital, Tubingen, Germany
    Philos Trans R Soc Lond B Biol Sci 366:1889-95. 2011
    ..This question poses a serious challenge whether the drug response in trials can be taken as evidence of drug effects in clinical routine...
  23. doi Acupuncture, psyche and the placebo response
    Paul Enck
    University Hospital Tubingen, Dept of Psychosomatic Medicine, Tubingen, Germany
    Auton Neurosci 157:68-73. 2010
    ..g. measures of the autonomic nervous system function to verify that acupuncture and sham acupuncture are different despite similar clinical effects...
  24. pmc Novel study designs to investigate the placebo response
    Paul Enck
    University Hospital Tubingen, Dept, of Psychosomatic Medicine, Tubingen, Germany
    BMC Med Res Methodol 11:90. 2011
    ..However, as the conventional design is thought to elucidate drug rather than placebo actions, different methodological procedures are needed for the placebo response...
  25. ncbi [Determination of placebo effect in irritable bowel syndrome]
    P Enck
    Medizinische Klinik VI Psychosomatische Medizin und Psychotherapie, Universitatsklinikum Tubingen
    Dtsch Med Wochenschr 130:1934-7. 2005
    ..The determinants of the placebo effect are not well established. Goal of this study was to explore likely predictive factors in an already published data set...
  26. doi Repeatability of innervation zone identification in the external anal sphincter muscle
    Paul Enck
    Department of Internal Medicine VI, University Hospitals Tubingen, Tubingen, Germany
    Neurourol Urodyn 29:449-57. 2010
    ..A method proposed for the automatic estimation of the distribution of IZs of EAS from high-density surface electromyography (EMG) was evaluated for repeatability in continent volunteers...
  27. doi Biofeedback therapy in fecal incontinence and constipation
    P Enck
    University Hospital, Department of Psychosomatic Medicine and Psychotherapy, Tubingen, Germany
    Neurogastroenterol Motil 21:1133-41. 2009
    ..BFT for pelvic floor dyssynergia shows substantial specific therapeutic effect while BFT for incontinence is still lacking evidence for efficacy. However, in both conditions the mode of BFT seems to play a minor role...
  28. ncbi [The placebo effect in medicine]
    P Enck
    Medizinische Universitätsklinik VI, Psychosomatische Medizin und Psychotherapie, Forschungsbereich, Universitatsklinikum Tubingen, Frondsbergstrasse 23, 72076, Tubingen, Deutschland
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 52:635-42. 2009
    ..g. on type, size, dynamics, determinants, and predictors of the placebo response in the literature...
  29. ncbi Electromyography of pelvic floor muscles
    Paul Enck
    Department of Internal Medicine VI, University Hospitals Tubingen, Psychosomatic Medicine, Osianderstr 5, 72076 Tubingen, Germany
    J Electromyogr Kinesiol 16:568-77. 2006
    ..The inputs from several higher centres influence the complex reflex control and are decisive for voluntary control, and for socially adapted behaviour related to excretory functions...
  30. ncbi [Placebo response in functional bowel disorders]
    P Enck
    Abteilung Innere Medizin VI Psychosomatische Medizin und Psychotherapie, Universitatsklinikum Tubingen
    Z Gastroenterol 44:257-66. 2006
    ..Potential biological mechanisms for the placebo response are discussed, including he possibility of the genetic predisposition to be a placebo responder...
  31. ncbi Innervation zones of the external anal sphincter in healthy male and female subjects. Preliminary results
    P Enck
    Department of General Surgery, University Hospitals Tubingen, Germany
    Digestion 69:123-30. 2004
    ..The objective of this work was to investigate the distribution of the innervation zones of the motor units that make up the external anal sphincter (EAS) in healthy males and females...
  32. ncbi Quality of life in patients with upper gastrointestinal symptoms: results from the Domestic/International Gastroenterology Surveillance Study (DIGEST)
    P Enck
    University of Tubingen, Germany
    Scand J Gastroenterol Suppl 231:48-54. 1999
    ....
  33. ncbi Upper and lower gastrointestinal motor and sensory dysfunction after human spinal cord injury
    Paul Enck
    Department of Psychosomatic Medicine, University Hospitals Tuingen, Schaffhausenstr 113, 72072 Tubingen, Germany
    Prog Brain Res 152:373-84. 2006
    ....
  34. ncbi The external anal sphincter and the role of surface electromyography
    P Enck
    Department of Internal Medicine VI, University Hospitals Tubingen, Germany
    Neurogastroenterol Motil 17:60-7. 2005
    ..This may eventually be transferred to a new understanding of the role of symmetry and asymmetry of pelvic floor innervation and its role in the pathogenesis of fecal incontinence...
  35. ncbi Functional asymmetry of pelvic floor innervation and its role in the pathogenesis of fecal incontinence
    Paul Enck
    Department of General Surgery, University Hospitals Tubingen, Germany
    Digestion 69:102-11. 2004
    ....
  36. ncbi The placebo response in functional bowel disorders: perspectives and putative mechanisms
    P Enck
    Department of Internal Medicine VI Psychosomatics, University Hospitals Tuebingen, Tuebingen, Germany
    Neurogastroenterol Motil 17:325-31. 2005
    ..Psychobiological mechanisms of the placebo response in functional and organic diseases can also be identified in brain function studies (such as imaging)...
  37. doi Reduction of motion sickness with an enhanced placebo instruction: an experimental study with healthy participants
    Björn Horing
    Department of Internal Medicine VI Psychosomatic Medicine and Psychotherapy, University Hospital, Frondsbergstr 23, 72076 Tubingen, Germany
    Psychosom Med 75:497-504. 2013
    ..Expectancy and conditioning are underlying mechanisms of placebo and nocebo responses. In previous studies with motion sickness, we could induce nocebo responses by both methods, but no placebo responses...
  38. doi Rome III criteria in parents' hands: pain-related functional gastrointestinal disorders in community children and associations with somatic complaints and mental health
    Marco D Gulewitsch
    Department of Psychology, Faculty of Science, University of Tubingen, Germany
    Eur J Gastroenterol Hepatol 25:1223-9. 2013
    ....
  39. doi Psychological dimensions after laparoscopic sleeve gastrectomy: reduced mental burden, improved eating behavior, and ongoing need for cognitive eating control
    Nicole Rieber
    Department of Internal Medicine, Psychosomatic Medicine and Psychotherapy, University Hospital Tubingen, Tubingen, Germany
    Surg Obes Relat Dis 9:569-73. 2013
    ..The setting was a university hospital, comprehensive obesity center...
  40. doi Impact of biofeedback on self-efficacy and stress reduction in obesity: a randomized controlled pilot study
    Martin Teufel
    Department of Internal Medicine, Psychosomatic Medicine and Psychotherapy, University Hospital Tubingen, Osianderstrasse 5, 72076, Tubingen, Germany
    Appl Psychophysiol Biofeedback 38:177-84. 2013
    ..Biofeedback treatment is effective in improving self-efficacy in individuals with obesity and might therefore be a valuable additional intervention in obesity treatment...
  41. doi Gender and the nocebo response following conditioning and expectancy
    Sibylle Klosterhalfen
    Department of Internal Medicine VI, University Hospital Tubingen, Tubingen, Germany
    J Psychosom Res 66:323-8. 2009
    ..To investigate the role of Pavlovian conditioning and expectancy and of gender on the nocebo effects...
  42. doi Attentional processing of food pictures in individuals with anorexia nervosa--an eye-tracking study
    Katrin E Giel
    Department of Psychosomatic Medicine and Psychotherapy, University Hospital Tubingen, Tubingen, Germany
    Biol Psychiatry 69:661-7. 2011
    ..The study's aim was to examine the vigilance-avoidance hypothesis concerning food information processing by unraveling the time course of attention deployment in individuals with AN...
  43. doi Assessment of relevant hepatic steatosis in obese adolescents by rapid fat-selective GRE imaging with spatial-spectral excitation: a quantitative comparison with spectroscopic findings
    Fabian Springer
    Section on Experimental Radiology, Department of Diagnostic and Interventional Radiology, University Hospital Tubingen, Hoppe Seyler Str 3, 72076 Tubingen, Germany
    Eur Radiol 21:816-22. 2011
    ..To test the feasibility of fat-selective GRE imaging using a spectral-spatial excitation technique for determination of intrahepatic lipid content (IHL) in obese adolescents...
  44. doi Motivation for psychotherapy in patients with functional gastrointestinal disorders
    Ute Martens
    University Hospitals, Tubingen, Department of Internal Medicine VI, Psychosomatic Medicine and Psychotherapy, Frondsbergstr 23, 72076 Tubingen, Germany
    Psychosomatics 51:225-9. 2010
    ..The motivation of patients with functional gastrointestinal disorders to accept psychotherapy (PT) as a treatment option is not known...
  45. ncbi Gender and race as determinants of nausea induced by circular vection
    Sibylle Klosterhalfen
    Institute of Medical Psychology, Heinrich Heine University, Dusseldorf, and Department of Internal Medicine, University Hospitals Tubingen, Germany
    Gend Med 3:236-42. 2006
    ..Within- and between-subject variability of susceptibility for motion sickness is well established, but which factors determine susceptibility is less well known...
  46. doi Body image after sleeve gastrectomy: reduced dissatisfaction and increased dynamics
    Martin Teufel
    Department of Internal Medicine, Psychosomatic Medicine and Psychotherapy, University Hospital Tubingen, Osianderstrasse 5, 72076 Tubingen, Germany
    Obes Surg 22:1232-7. 2012
    ..However, no studies investigating body image after laparoscopic sleeve gastrectomy (LSG) are available...
  47. ncbi Asymmetric sphincter innervation is associated with fecal incontinence after anal sphincter trauma during childbirth
    Beate M Wietek
    Department of Diagnostic Radiology, University of Tubingen, Tubingen, Germany
    Neurourol Urodyn 26:134-9. 2007
    ..However, this remains to be shown for different clinical conditions such as traumatic childbirth...
  48. doi Processing of pictorial food stimuli in patients with eating disorders--a systematic review
    Katrin Elisabeth Giel
    Department of Psychosomatic Medicine and Psychotherapy, Medical University Hospital Tuebingen, Tuebingen 72076, Germany
    Int J Eat Disord 44:105-17. 2011
    ..The processing of food cues in eating-disordered patients has recently been increasingly investigated. Outlined is current evidence from pictorial food stimuli studies...
  49. doi Effects of short-term food deprivation on interoceptive awareness, feelings and autonomic cardiac activity
    Beate M Herbert
    Department of Psychosomatic Medicine and Psychotherapy, University Hospital Tuebingen, Eberhard Karls University Tuebingen, Germany
    Biol Psychol 89:71-9. 2012
    ..Additionally, the results demonstrate the role of cardiac vagal activity as a potential index of emotion related self-regulation, for hunger, mood and the affective appraisal of interoceptive signals during acute fasting...
  50. ncbi Placebo responses in patients with gastrointestinal disorders
    Frauke Musial
    Department of Internal Medicine, Integrative and Complementary Medicine, Kliniken Essen Mitte, Knappschafts Krankenhaus, Am Deimelsberg 34a, Essen 45276, Germany
    World J Gastroenterol 13:3425-9. 2007
    ....
  51. ncbi Effects of laparoscopic sleeve gastrectomy on attentional processing of food-related information: evidence from eye-tracking
    Katrin E Giel
    Department of Psychosomatic Medicine and Psychotherapy, Medical University Hospital Tübingen, Tubingen, Germany Electronic address
    Surg Obes Relat Dis 10:277-82. 2014
    ..We investigated if food cue processing is altered 6 months after weight loss that is induced by LSG. We expected patients after LSG to show reduced appetitive responses to food cues...
  52. doi Placebo effects in children: a review
    Katja Weimer
    Department of Psychosomatic Medicine and Psychotherapy, University Hospital Tubingen, Tubingen, Germany
    Pediatr Res 74:96-102. 2013
    ..We finally discuss some of the consequences from the current placebo research in adults that may affect both experimental and clinical research in children and adolescents. ..
  53. doi Nicotine stimulus expectancy differentially affects reaction time in healthy nonsmokers and smokers depending on sex: a pilot study
    Katja Weimer
    Department of Psychosomatic Medicine and Psychotherapy, University Hospital Tubingen, Germany
    Exp Clin Psychopharmacol 21:181-7. 2013
    ..Therefore, the known effects of nicotine on RTs could be influenced by stimulus expectancy not only in smokers but also in nonsmokers. Furthermore, previous results on sex-specific responsiveness to nicotine instructions are supported...
  54. doi Effects of medical training scenarios on heart rate variability and motivation in students and simulated patients
    Nicole Rieber
    Department of Internal Medicine VI, Psychosomatic Medicine and Psychotherapy, University of Tübingen Medical Hospital, Tubingen, Germany
    Med Educ 43:553-6. 2009
    ....
  55. ncbi Gastric emptying effects of dietary fiber during 8 hours at two simulated cabin altitudes
    Heidemarie Hinninghofen
    Internal Medicine VI, Psychosomatic Medicine and Psychotherapy, University Hospitals Tubingen, Tubingen, Germany
    Aviat Space Environ Med 77:121-3. 2006
    ..36%). To elucidate the reason for increased frequency of gastrointestinal symptoms during long-distance flights, we investigated the effects of altitude and diet on gastric emptying, cardiovascular function, and bodily complaints...
  56. ncbi [Screening for mental stress and the wish for psychological support in patients with breast cancer]
    Norbert Schäffeler
    Universitatsklinikum Tubingen, Abteilung Innere Medizin VI Psychosomatische Medizin und Psychotherapie, Osianderstr 5, 72076 Tubingen
    Z Psychosom Med Psychother 56:207-19. 2010
    ..We also explored whether scores on HADS-D and PHQ-D identify the same patients as being stressed as well as the relationship between patient's wish for psychological support and psychological strain...
  57. pmc mu-Opiate receptor agonists -- a new pharmacological approach to prevent motion sickness?
    Bärbel Otto
    Department of Internal Medicine, Innenstadt, University Hospital, Munich, Germany
    Br J Clin Pharmacol 61:27-30. 2006
    ..Stress hormones might be involved in motion sickness. The influence of loperamide on kinetosis-induced nausea and stress hormone release was investigated in a placebo-controlled, cross-over study...
  58. doi Olfactory deficits in patients with anorexia nervosa
    Nora Rapps
    Department of Psychosomatic Medicine and Psychotherapy, Medical University Hospital Tuebingen, Tuebingen, Germany
    Eur Eat Disord Rev 18:385-9. 2010
    ..The question arises if patients with eating disorders have changes in olfactory functions as well. The aim of this study was to compare olfactory functions in patients with AN and controls using the Sniffin' sticks...
  59. ncbi Nausea induced by vection drum: contributions of body position, visual pattern, and gender
    Sibylle Klosterhalfen
    Department of Internal Medicine Psychosomatics, University Hospital Tubingen, Tubingen, Germany
    Aviat Space Environ Med 79:384-9. 2008
    ..The purpose of this work was to investigate intrinsic (gender) and extrinsic factors (body position, visual pattern) and their relative contribution to the development of motion sickness during pseudo-rotation...
  60. ncbi Psychological burden of food allergy
    Martin Teufel
    Department of Internal Medicine VI Psychosomatic Medicine and Psychotherapy, University of Tubingen, Osianderstrasse 5, D 72076 Tubingen, Germany
    World J Gastroenterol 13:3456-65. 2007
    ....
  61. doi Brain imaging of visceral functions in healthy volunteers and IBS patients
    Nora Rapps
    Department of Internal Medicine VI Psychosomatic Medicine and Psychotherapy, University of Tubingen, Tubingen, Germany
    J Psychosom Res 64:599-604. 2008
    ..Subsequently, this article will deal with those brain areas activated by visceral stimulation in IBS patients. Special attention will be paid to recently published studies concerning psychological factors and novel research questions...
  62. doi A community-based survey of abdominal pain prevalence, characteristics, and health care use among children
    Ilja Juliane Dorothee Schwille
    Department of Internal Medicine VI, Psychosomatic Medicine and Psychotherapy, University Hospital Tuebingen, Tuebingen 72076, Germany
    Clin Gastroenterol Hepatol 7:1062-8. 2009
    ..By using data collected from this survey, we evaluated the prevalence and characteristics of abdominal pain and assessed health care use...
  63. doi Psychological effects of prevention: do participants of a type 2 diabetes prevention program experience increased mental distress?
    Katrin E Giel
    Department of Internal Medicine VI Psychosomatic Medicine and Psychotherapy, University Hospital Tuebingen, Germany
    Diabetes Metab Res Rev 25:83-8. 2009
    ..To evaluate the mental health outcome of a lifestyle intervention for the prevention of type 2 diabetes and to exclude possible harmful psychological effects...
  64. ncbi [Body image and psychiatric comorbidity in patients with somatoform gastrointestinal disorders]
    Ute Martens
    Medizinische Klinik und Poliklinik, Abteilung Psychosomatische Medzin und Psychotherapie, Universitatsklinikum Tubingen
    Z Psychosom Med Psychother 56:47-55. 2010
    ....
  65. ncbi Fecal incontinence: evaluation and treatment
    Heidemarie Hinninghofen
    University Hospital Tuebingen, Schaffhausenstrasse 113, 72072 Tuebingen, Germany
    Gastroenterol Clin North Am 32:685-706. 2003
    ..They are less attractive because of technical difficulties and low success rate. A multidisciplinary approach to treatment has the potential to improve the outcome for patients with fecal incontinence...
  66. ncbi Stress-induced attenuation of brain stem activation following intestinal anaphylaxis in the rat
    M E Kreis
    Universitat Tubingen, Klinik für Allgemeine Chirurgie, Waldhornlestrasse 22, D 72072 Tubingen, Germany
    Neurosci Lett 345:187-91. 2003
    ..This may have implications for a potential efferent neuronal modulation of inflammatory responses in the gut...
  67. doi Cortical processing of residual ano-rectal sensation in patients with spinal cord injury: an fMRI study
    B M Wietek
    Section on Experimental Radiology, Department of Diagnostic Radiology, University Hospital Tubingen, Tubingen, Germany
    Neurogastroenterol Motil 20:488-97. 2008
    ....
  68. ncbi Passenger well-being in airplanes
    H Hinninghofen
    University Hospitals Tubingen, Internal Medicine VI, Psychosomatic Medicine and Psychotherapy, Fronsbergstrasse 23, D 72070 Tubingen, Germany
    Auton Neurosci 129:80-5. 2006
    ..Individual passenger characteristics and health status also have been demonstrated to increase vulnerability to adverse health outcomes and discomfort...
  69. doi Neurophysiology and psychobiology of the placebo response
    Sibylle Klosterhalfen
    Department of Internal Medicine VI Psychosomatics, University Hospital Tubingen, Germany
    Curr Opin Psychiatry 21:189-95. 2008
    ..The placebo literature has substantially increased in 2006 and 2007, and more and more medical and psychological subspecialties have added empirical data to our knowledge...
  70. ncbi Functional cortical imaging of nausea and vomiting: a possible approach
    Axel Kowalski
    Internal Medicine VI, Psychosomatic Medicine and Psychotherapy, University Hospital Tubingen, Frondsbergstr 23, D 72076 Tubingen, Germany
    Auton Neurosci 129:28-35. 2006
    ..This paper presents a brief outline for a study on the functional imaging of nauseated humans by means of functional magnetic resonance imaging (fMRI)...
  71. ncbi Irritable bowel syndrome and chronic pelvic pain: a singular or two different clinical syndrome?
    Anna Matheis
    Department of Sychosomatic Medicine and Psychotherapy University Hospitals Tubingen, Frondsbergstrasse 23, Tubingen 72076, Germany
    World J Gastroenterol 13:3446-55. 2007
    ..Nevertheless both are traded as different clinical pictures as far. Therefore it seems to be reasonable and necessary to generate a common diagnosis algorithm and to bring gynaecologists and gastroenterologists into dialogue...
  72. ncbi Functional imaging of stress urinary incontinence
    A M R Di Gangi Herms
    Institute of Medical Psychology and Behavioral Neurobiology, University of Tubingen, Gartenstrasse 29 D 72074 Tübingen, Germany
    Neuroimage 29:267-75. 2006
    ..The changes in EMG-activity were correlated with heightened BOLD responses in the primary motor and primary sensory cortical representation sites of the lower urogenital tract...
  73. pmc Acupuncture treatment in irritable bowel syndrome
    A Schneider
    Department of General Practice and Health Services Research, University Medical Hospital, University of Heidelberg, Vossstrasse 2, 69120 Heidelberg, Germany
    Gut 55:649-54. 2006
    ..Despite occasional positive reports on the efficacy of acupuncture (AC) on functions of the gastrointestinal tract, there is no conclusive evidence that AC is effective in the treatment of irritable bowel syndrome (IBS)...
  74. doi The functional muscle-bone unit in obese children - altered bone structure leads to normal strength strain index
    S Ehehalt
    Pediatric Endocrinology and Diabetology, University Children s Hospital, Tuebingen, Germany
    Exp Clin Endocrinol Diabetes 119:321-6. 2011
    ..Obese children have a twofold increased risk of fracture of the forearm compared to non-obese children...
  75. ncbi Cerebral activation during anal and rectal stimulation
    M Lotze
    Institute of Medical Psychology and Behavioral Neurobiology, , , D-72074, Germany
    Neuroimage 14:1027-34. 2001
    ..This motor response following aversive somatosensory stimuli may be caused by a reflexive avoidance reaction which is not observed after the more diffuse experienced visceral stimulation...
  76. ncbi Functional asymmetry of pelvic floor innervation--myth or fact?
    Paul Enck
    Department of General Surgery, University Hospital Tubingen
    Folia Med Cracov 45:51-61. 2004
    ..These facts have the clinical relevance in case of pelvic floor trauma or incontinence surgery. New techniques of EMG are necessary to confirm correlations between symptoms development and asymmetry of sphincter innervation...
  77. pmc Recurrent abdominal pain in children and adolescents - a survey among paediatricians
    Angelika A Schlarb
    Department of Clinical and Developmental Psychology, University of Tubingen, Germany
    Psychosoc Med 8:Doc02. 2011
    ..Conclusions: Estimated frequencies and paediatricians' demands show the need for evidence-based psychological interventions in RAP to support usual medical treatment...
  78. doi Normal-weight 14-year-old girl with acanthosis nigricans and markedly increased hepatic steatosis: evidence for the important role of ectopic fat deposition in the pathogenesis of insulin resistance in childhood and adolescence
    Fabian Springer
    Section on Experimental Radiology, Department of Diagnostic and Interventional Radiology, University Hospital Tubingen, Tubingen, Germany
    Horm Res Paediatr 74:376-80. 2010
    ..A major factor in the development of insulin resistance is obesity. While the contribution of intrahepatic lipids to insulin resistance is well established in adults, there are only few reports in childhood and adolescence...
  79. ncbi Acute tryptophan depletion increases experimental nausea but also induces hunger in healthy female subjects
    N Rieber
    Department of Internal Medicine VI, University of Tubingen, Tubingen, Germany
    Neurogastroenterol Motil 22:752-7, e220. 2010
    ..Acute tryptophan depletion (ATD) is an experimental model to reduce central serotonin levels...
  80. ncbi Endocrine correlates of acute nausea and vomiting
    Bärbel Otto
    Medical Department Innenstadt, University Hospitals of Munich, Ziemssenstr 1, D 80336 Munich, Germany
    Auton Neurosci 129:17-21. 2006
    ..Although gastroenteropancreatic hormones are involved in gastrointestinal motility, there are only few data describing their changes in response to acute nausea or vomiting...
  81. ncbi Pavlovian conditioning of nausea and vomiting
    Ursula Stockhorst
    Institute of Medical Psychology, Heinrich Heine University Duesseldorf, Germany
    Auton Neurosci 129:50-7. 2006
    ..The paper concludes with a review of applications of the demonstrated conditioning principles as interventions to ameliorate distressing anticipatory nausea or anticipatory vomiting in cancer patients undergoing chemotherapy...
  82. ncbi Anorectal functional testing: review of collective experience
    Fernando Azpiroz
    Digestive System Research Unit, Hospital General Vall d Hebron, Barcelona, Spain
    Am J Gastroenterol 97:232-40. 2002
    ....
  83. doi Psychophysiology of visceral pain in IBS and health
    Frauke Musial
    Complementary and Integrative Medicine, University of Duisburg Essen, Department of Internal Medicine, Kliniken Essen Mitte, Germany
    J Psychosom Res 64:589-97. 2008
    ....
  84. ncbi Segregation of visceral and somatosensory afferents: an fMRI and cytoarchitectonic mapping study
    Simon B Eickhoff
    Institut for Medizin, Research Centre Julich, Germany
    Neuroimage 31:1004-14. 2006
    ..Rather, they evoked activation at a more anterior location on the precentral operculum. These results demonstrate a functionally and anatomically distinct processing of somatosensory and visceral afferents in the human cerebral cortex...
  85. ncbi Psychobiology of the placebo response
    Sibylle Klosterhalfen
    Institute for Medical Psychology, University Hospitals Duesseldorf, Germany
    Auton Neurosci 125:94-9. 2006
    ....
  86. ncbi Effects of ethnicity and gender on motion sickness susceptibility
    Sibylle Klosterhalfen
    Institute of Medical Psychology, University of Dusseldorf, Germany
    Aviat Space Environ Med 76:1051-7. 2005
    ..Susceptibility to motion sickness (MS) is known to be affected by gender and ethnic origin, but whether gender and ethnicity are interacting is unknown...
  87. ncbi Sex-specific adaptation of endocrine and inflammatory responses to repeated nauseogenic body rotation
    Nicolas Rohleder
    Department of Biopsychology, University of Technology Dresden, Zellescher Weg 17, 01069 Dresden, Germany
    Psychoneuroendocrinology 31:226-36. 2006
    ..These presumably unfavorable changes in the inflammatory system are more pronounced men...
  88. ncbi [Placebos in clinic and research: experimental findings and theoretical concepts]
    Sibylle Klosterhalfen
    Institut fur Medizinische Psychologie, Universitatsklinikum Dusseldorf
    Psychother Psychosom Med Psychol 55:433-41. 2005
    ..Potential biological mechanisms for the placebo response are discussed, including the possibility of genetic predisposition to be a placebo responder...
  89. ncbi Latent inhibition of rotation chair-induced nausea in healthy male and female volunteers
    Sibylle Klosterhalfen
    Institute of Medical Psychology, University Hospitals Düsseldorf, Dusseldorf, Germany
    Psychosom Med 67:335-40. 2005
    ..Pre-exposure to an environment in which a nausea-inducing body rotation will subsequently be given constitutes a latent inhibition procedure that might act to reduce anticipatory and postrotation nausea...
  90. ncbi Irritable bowel syndrome: a single gastrointestinal disease or a general somatoform disorder?
    Paul Enck
    J Psychosom Res 64:561-5. 2008
  91. ncbi Role of classical conditioning in learning gastrointestinal symptoms
    Ursula Stockhorst
    Institute of Psychology, General Psychology II and Biological Psychology, University of Osnabrueck, Osnabrueck, Seminarstrasse 20, D 49074 Osnabrueck, Germany
    World J Gastroenterol 13:3430-7. 2007
    ..This paper concludes with a review of the application of the demonstrated conditioning principles as interventions to ameliorate distressing AN/ANV in cancer patients undergoing chemotherapy, which is the second focus of our work...
  92. ncbi Functional anorectal disorders
    Adil E Bharucha
    Mayo Clinic, Rochester, Minnesota, USA
    Gastroenterology 130:1510-8. 2006
    ..Functional disorders of defecation may be amenable to pelvic floor retraining by biofeedback therapy (such as dyssynergic defecation)...
  93. ncbi Temporal characteristics of feeding behavior in the Munich miniature pig
    Frauke Musial
    Biological and Clinical Psychology, Friedrich Schiller University, Am Steiger 3 Haus 1, D 07743 Jena, Germany
    Physiol Behav 87:206-18. 2006
    ..Stability increased over time and feeding was more stable during the light period. Both correlation measures revealed a strong association between meal size and inter-meal intervals...
  94. ncbi Postoperative colonic motility increases after early food intake in patients undergoing colorectal surgery
    Michael S Kasparek
    Department of General Surgery, University Hospital Tuebingen, Tuebingen Germany
    Surgery 136:1019-27. 2004
    ..We aimed to investigate whether postoperative colonic motility is increased after early food intake...