A H Elmaagacli

Summary

Country: Germany

Publications

  1. ncbi A comparison of chimerism and minimal residual disease between four different allogeneic transplantation methods in patients with chronic myelogenous leukemia in first chronic phase
    A H Elmaagacli
    Department of Bone Marrow Transplantation, University Hospital Essen, Essen, Germany
    Bone Marrow Transplant 27:809-15. 2001
  2. doi Relation of an interleukin-23 receptor gene polymorphism to graft-versus-host disease after hematopoietic-cell transplantation
    A H Elmaagacli
    Department of Bone Marrow Transplantation, University Hospital of Essen, Essen, Germany
    Bone Marrow Transplant 41:821-6. 2008
  3. doi Toll-like receptor 9, NOD2 and IL23R gene polymorphisms influenced outcome in AML patients transplanted from HLA-identical sibling donors
    A H Elmaagacli
    Department of Bone Marrow Transplantation, University Hospital of Essen, Essen, Germany
    Bone Marrow Transplant 46:702-8. 2011
  4. ncbi Cytochrome P450 2C19 loss-of-function polymorphism is associated with an increased treatment-related mortality in patients undergoing allogeneic transplantation
    A H Elmaagacli
    Department of Bone Marrow Transplantation, University Hospital of Essen, Essen, Germany
    Bone Marrow Transplant 40:659-64. 2007
  5. ncbi Outcome of hematopoietic stem cell transplantation in patients with atypical chronic myeloid leukemia
    M Koldehoff
    Department of Bone Marrow Transplantation, University Hospital of Essen, Hufelandstr, 55, 45122 Essen, Germany
    Bone Marrow Transplant 34:1047-50. 2004
  6. ncbi Estimating the relapse stage in chronic myeloid leukaemia patients after allogeneic stem cell transplantation by the amount of BCR-ABL fusion transcripts detected using a new real-time polymerase chain reaction method
    A H Elmaagacli
    Department of Bone Marrow Transplantation and Internal Medicine Cancer Research, University Hospital of Essen, Essen, Germany
    Br J Haematol 113:1072-5. 2001
  7. ncbi Successful treatment of patients with respiratory failure due to fungal infection after allogeneic hematopoietic stem cell transplantation
    M Koldehoff
    Department of Bone Marrow Transplantation, University Hospital of Essen, Essen, Germany
    Transpl Infect Dis 7:137-45. 2005
  8. ncbi Caspofungin as second-line therapy for fever of unknown origin or invasive fungal infection following allogeneic stem cell transplantation
    R Trenschel
    Department of Bone Marrow Transplantation, University Hospital Essen, Essen, Germany
    Bone Marrow Transplant 35:583-6. 2005
  9. ncbi Myeloablative allogeneic hematopoietic stem cell transplantation in elderly patients
    M Ditschkowski
    Department of Bone Marrow Transplantation, University Hospital of Essen, Hufelandstr, Essen, Germany
    Clin Transplant 20:127-31. 2006
  10. ncbi Outcome of allogeneic stem cell transplantation in patients with myelofibrosis
    M Ditschkowski
    Department of Bone Marrow Transplantation, University Hospital of Essen, Hufelandstr 55, 45122 Essen, Germany
    Bone Marrow Transplant 34:807-13. 2004

Collaborators

Detail Information

Publications18

  1. ncbi A comparison of chimerism and minimal residual disease between four different allogeneic transplantation methods in patients with chronic myelogenous leukemia in first chronic phase
    A H Elmaagacli
    Department of Bone Marrow Transplantation, University Hospital Essen, Essen, Germany
    Bone Marrow Transplant 27:809-15. 2001
    ..Only five of nine patients (55%) after CD34(+) PBSCT and 19 of 33 patients (58%) after BMT achieved CC compared to 19 of 22 (86%) patients after PBSCT and seven of eight (88%) patients after PBSCT with reduced conditioning (P < 0.05)...
  2. doi Relation of an interleukin-23 receptor gene polymorphism to graft-versus-host disease after hematopoietic-cell transplantation
    A H Elmaagacli
    Department of Bone Marrow Transplantation, University Hospital of Essen, Essen, Germany
    Bone Marrow Transplant 41:821-6. 2008
    ..Among recipients of hematopoietic cells from HLA-identical donors, the IL-23R (Arg381Gln) gene variant on the donor side has a protective effect on the occurrence of acute GVHD in recipients after transplantation...
  3. doi Toll-like receptor 9, NOD2 and IL23R gene polymorphisms influenced outcome in AML patients transplanted from HLA-identical sibling donors
    A H Elmaagacli
    Department of Bone Marrow Transplantation, University Hospital of Essen, Essen, Germany
    Bone Marrow Transplant 46:702-8. 2011
    ..These results suggest that the gene variants of TLR9, NOD2 and Il23R had influence on the outcome of transplant...
  4. ncbi Cytochrome P450 2C19 loss-of-function polymorphism is associated with an increased treatment-related mortality in patients undergoing allogeneic transplantation
    A H Elmaagacli
    Department of Bone Marrow Transplantation, University Hospital of Essen, Essen, Germany
    Bone Marrow Transplant 40:659-64. 2007
    ..These results suggest that genotyping for CYP450 2C19 can help to identify patients with higher risk for TRM...
  5. ncbi Outcome of hematopoietic stem cell transplantation in patients with atypical chronic myeloid leukemia
    M Koldehoff
    Department of Bone Marrow Transplantation, University Hospital of Essen, Hufelandstr, 55, 45122 Essen, Germany
    Bone Marrow Transplant 34:1047-50. 2004
    ..All other patients were alive at the time of analysis. Our findings suggest that the outcome of allogeneic or syngeneic transplantation in patients with aCML may not be worse than the outcome of transplantation for BCR-ABL-positive CML...
  6. ncbi Estimating the relapse stage in chronic myeloid leukaemia patients after allogeneic stem cell transplantation by the amount of BCR-ABL fusion transcripts detected using a new real-time polymerase chain reaction method
    A H Elmaagacli
    Department of Bone Marrow Transplantation and Internal Medicine Cancer Research, University Hospital of Essen, Essen, Germany
    Br J Haematol 113:1072-5. 2001
    ..06% (range 0.001-1.55%), 3.2% (range 1.4-5.6%) and 21.5% (range 6.8 -827%) in 17 patients with a molecular relapse, in eight patients with a cytogenetic relapse and in 10 patients with a haematological relapse respectively...
  7. ncbi Successful treatment of patients with respiratory failure due to fungal infection after allogeneic hematopoietic stem cell transplantation
    M Koldehoff
    Department of Bone Marrow Transplantation, University Hospital of Essen, Essen, Germany
    Transpl Infect Dis 7:137-45. 2005
    ....
  8. ncbi Caspofungin as second-line therapy for fever of unknown origin or invasive fungal infection following allogeneic stem cell transplantation
    R Trenschel
    Department of Bone Marrow Transplantation, University Hospital Essen, Essen, Germany
    Bone Marrow Transplant 35:583-6. 2005
    ..CAS is a promising alternative in patients with IFI and fever of unknown origin in the setting of allogeneic SCT...
  9. ncbi Myeloablative allogeneic hematopoietic stem cell transplantation in elderly patients
    M Ditschkowski
    Department of Bone Marrow Transplantation, University Hospital of Essen, Hufelandstr, Essen, Germany
    Clin Transplant 20:127-31. 2006
    ..0001) were identified. These results show that hematopoietic SCT following myeloablative conditioning is also applicable to elderly patients whereas disease stage and high-grade GVHD represent the essential prognostic factors for outcome...
  10. ncbi Outcome of allogeneic stem cell transplantation in patients with myelofibrosis
    M Ditschkowski
    Department of Bone Marrow Transplantation, University Hospital of Essen, Hufelandstr 55, 45122 Essen, Germany
    Bone Marrow Transplant 34:807-13. 2004
    ..Our data suggest that transplantation should be taken into consideration before poor prognostic variables develop...
  11. ncbi Disease- or therapy-related bone marrow damage cannot be overcome by changes in stem cell source or dose in allogeneic transplantation
    J R Novotny
    Department of Haematology, University of Essen, Essen, Germany
    Eur J Haematol 73:1-9. 2004
    ....
  12. doi Improved outcome of hematopoietic SCT in patients with homozygous gene variant of Toll-like receptor 9
    A H Elmaagacli
    Department of Bone Marrow Transplantation, University Hospital of Essen, Essen, Germany
    Bone Marrow Transplant 44:295-302. 2009
    ..In vitro studies using CpG-rich ODNs showed an upregulation of TLR9 expression in cell lines with CC gene variant, but not in cell lines with wild-type gene...
  13. doi Bronchiolitis obliterans after allogeneic hematopoietic SCT: further insight-new perspectives?
    M Ditschkowski
    Department of Bone Marrow Transplantation, WTZ, Comprehensive Cancer Centre, University Hospital Essen, Essen, Germany
    Bone Marrow Transplant 48:1224-9. 2013
    ..04). These results emphasize the relevance of BO as serious late complication with substantial mortality and point to essential pathophysiological changes due to regulatory responses to hypoxia. ..
  14. ncbi Allogeneic CD34-enriched peripheral blood stem cell transplantation in a patient with paroxysmal nocturnal haemoglobinuria
    M Ditschkowski
    Department for Bone Marrow Transplantation, University Hospital of Essen, Essen, Germany
    Bone Marrow Transplant 32:633-5. 2003
    ..We conclude that PNH may be cured by allogeneic CD34-enriched SCT from a sibling donor attempting to avoid acute GVHD and to reduce cumulative organ toxicity by using this transplantation modality...
  15. ncbi Therapeutic application of small interfering RNA directed against bcr-abl transcripts to a patient with imatinib-resistant chronic myeloid leukaemia
    M Koldehoff
    Department of Bone Marrow Transplantation, University of Duisburg Essen, Hufelandstr 55, 45122 Essen, Germany
    Clin Exp Med 7:47-55. 2007
    ..Our findings imply that the clinical application of synthetic siRNA is feasible, safe and has real potential for genetic-based therapies using synthetic non-viral carriers...
  16. doi Additive antileukemia effects by GFI1B- and BCR-ABL-specific siRNA in advanced phase chronic myeloid leukemic cells
    M Koldehoff
    Department of Bone Marrow Transplantation, West German Cancer Center, Faculty of Medicine, University of Duisburg Essen, Essen, Germany
    Cancer Gene Ther 20:421-7. 2013
    ....
  17. ncbi Impact of HLA-A,B,C allele mismatches on outcome after unrelated blood stem cell transplantation in whites
    H D Ottinger
    Department of Bone Marrow Transplantation, University Hospital of Essen, Germany
    Transplantation 78:1077-80. 2004
    ..Thus, our series of white donor/recipient pairs does not suggest the routine use of HLA-A,B,C SBT to improve HSCT outcome substantially...
  18. ncbi Indoleamine 2,3-dioxygenase expression in patients with acute graft-versus-host disease after allogeneic stem cell transplantation and in pregnant women: association with the induction of allogeneic immune tolerance?
    N K Steckel
    Department of Bone Marrow Transplantation and Department of Gynecology, University Hospital of Essen, Essen, Germany
    Scand J Immunol 57:185-91. 2003
    ..These data suggest that IDO expression might be involved in the development of allogeneic immune tolerance...