Graeme Eisenhofer

Summary

Country: Germany

Publications

  1. ncbi request reprint Low molecular weight proteomic information distinguishes metastatic from benign pheochromocytoma
    F M Brouwers
    Reproductive Biology and Medicine Branch, National Institute of Child Health and Human Development, Bethesda, Maryland 20892 1109, USA
    Endocr Relat Cancer 12:263-72. 2005
  2. ncbi request reprint Pheochromocytoma as a catecholamine producing tumor: implications for clinical practice
    T Zelinka
    Reproductive Biology and Medicine Branch, National Institutes of Child Health and Human Development, Bethesda, MD 20892 1109, USA
    Stress 10:195-203. 2007
  3. doi request reprint Regulation of endothelial protein C receptor shedding by cytokines is mediated through differential activation of MAP kinase signaling pathways
    Mario Menschikowski
    Institute of Clinical Chemistry and Laboratory Medicine, Technical University of Dresden, Medical Faculty Carl Gustav Carus, Fetscherstrasse 74, Dresden, Germany
    Exp Cell Res 315:2673-82. 2009
  4. doi request reprint Reference intervals for plasma free metanephrines with an age adjustment for normetanephrine for optimized laboratory testing of phaeochromocytoma
    Graeme Eisenhofer
    Institute of Clinical Chemistry and Laboratory Medicine, University Hospital of Dresden, 01307 Dresden, Germany
    Ann Clin Biochem 50:62-9. 2013
  5. pmc Plasma methoxytyramine: a novel biomarker of metastatic pheochromocytoma and paraganglioma in relation to established risk factors of tumour size, location and SDHB mutation status
    Graeme Eisenhofer
    Institute of Clinical Chemistry and Laboratory Medicine, University of Dresden, Dresden, Germany
    Eur J Cancer 48:1739-49. 2012
  6. pmc Genetic screening for von Hippel-Lindau gene mutations in non-syndromic pheochromocytoma: low prevalence and false-positives or misdiagnosis indicate a need for caution
    G Eisenhofer
    Institute of Clinical Chemistry and Laboratory Medicine and Department of Medicine III, University of Dresden, Fetscherstrasse 74, Dresden, Germany
    Horm Metab Res 44:343-8. 2012
  7. doi request reprint Diagnostic tests and biomarkers for pheochromocytoma and extra-adrenal paraganglioma: from routine laboratory methods to disease stratification
    Graeme Eisenhofer
    Institute of Clinical Chemistry and Laboratory Medicine and Department of Medicine III, University of Dresden, Fetscherstrasse 74, 01307, Dresden, Germany
    Endocr Pathol 23:4-14. 2012
  8. doi request reprint Screening for pheochromocytomas and paragangliomas
    Graeme Eisenhofer
    Institute of Clinical Chemistry and Laboratory Medicine, University of Dresden, Fetscherstrasse 74, 01307, Dresden, Germany
    Curr Hypertens Rep 14:130-7. 2012
  9. doi request reprint Current progress and future challenges in the biochemical diagnosis and treatment of pheochromocytomas and paragangliomas
    G Eisenhofer
    Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus Dresden, Germany
    Horm Metab Res 40:329-37. 2008
  10. pmc Differential expression of the regulated catecholamine secretory pathway in different hereditary forms of pheochromocytoma
    Graeme Eisenhofer
    Institute of Clinical Chemistry and Laboratory Medicine, University of Dresden, Dresden, Germany
    Am J Physiol Endocrinol Metab 295:E1223-33. 2008

Collaborators

Detail Information

Publications44

  1. ncbi request reprint Low molecular weight proteomic information distinguishes metastatic from benign pheochromocytoma
    F M Brouwers
    Reproductive Biology and Medicine Branch, National Institute of Child Health and Human Development, Bethesda, Maryland 20892 1109, USA
    Endocr Relat Cancer 12:263-72. 2005
    ..In the future, measurement of these biomarkers could be potentially used to improve the ability to identify patients with metastatic disease...
  2. ncbi request reprint Pheochromocytoma as a catecholamine producing tumor: implications for clinical practice
    T Zelinka
    Reproductive Biology and Medicine Branch, National Institutes of Child Health and Human Development, Bethesda, MD 20892 1109, USA
    Stress 10:195-203. 2007
    ..Although prognosis after tumor resection is excellent, a significant proportion of pheochromocytomas recur, some as metastases. Thus, appropriate follow-up is mandatory...
  3. doi request reprint Regulation of endothelial protein C receptor shedding by cytokines is mediated through differential activation of MAP kinase signaling pathways
    Mario Menschikowski
    Institute of Clinical Chemistry and Laboratory Medicine, Technical University of Dresden, Medical Faculty Carl Gustav Carus, Fetscherstrasse 74, Dresden, Germany
    Exp Cell Res 315:2673-82. 2009
    ..In summary, the shedding of EPCR in HUVEC is effectively regulated by IL-1beta and TNF-alpha, and downstream by MAP kinase signaling pathways and metalloproteinases...
  4. doi request reprint Reference intervals for plasma free metanephrines with an age adjustment for normetanephrine for optimized laboratory testing of phaeochromocytoma
    Graeme Eisenhofer
    Institute of Clinical Chemistry and Laboratory Medicine, University Hospital of Dresden, 01307 Dresden, Germany
    Ann Clin Biochem 50:62-9. 2013
    ..Upper cut-offs set too high compromise diagnostic sensitivity, whereas set too low, false-positives are a problem. This study aimed to establish optimal reference intervals for plasma normetanephrine and metanephrine...
  5. pmc Plasma methoxytyramine: a novel biomarker of metastatic pheochromocytoma and paraganglioma in relation to established risk factors of tumour size, location and SDHB mutation status
    Graeme Eisenhofer
    Institute of Clinical Chemistry and Laboratory Medicine, University of Dresden, Dresden, Germany
    Eur J Cancer 48:1739-49. 2012
    ..There are currently no reliable biomarkers for malignant pheochromocytomas and paragangliomas (PPGLs). This study examined whether measurements of catecholamines and their metabolites might offer utility for this purpose...
  6. pmc Genetic screening for von Hippel-Lindau gene mutations in non-syndromic pheochromocytoma: low prevalence and false-positives or misdiagnosis indicate a need for caution
    G Eisenhofer
    Institute of Clinical Chemistry and Laboratory Medicine and Department of Medicine III, University of Dresden, Fetscherstrasse 74, Dresden, Germany
    Horm Metab Res 44:343-8. 2012
    ..Caution should therefore be exercised in interpreting positive genetic test results as the cause of disease in patients with non-syndromic PPGLs...
  7. doi request reprint Diagnostic tests and biomarkers for pheochromocytoma and extra-adrenal paraganglioma: from routine laboratory methods to disease stratification
    Graeme Eisenhofer
    Institute of Clinical Chemistry and Laboratory Medicine and Department of Medicine III, University of Dresden, Fetscherstrasse 74, 01307, Dresden, Germany
    Endocr Pathol 23:4-14. 2012
    ....
  8. doi request reprint Screening for pheochromocytomas and paragangliomas
    Graeme Eisenhofer
    Institute of Clinical Chemistry and Laboratory Medicine, University of Dresden, Fetscherstrasse 74, 01307, Dresden, Germany
    Curr Hypertens Rep 14:130-7. 2012
    ..Additional measurements of methoxytyramine, the metabolite of dopamine, can be useful in patients with mutations of succinate dehydrogenase genes or patients who are at risk for malignancy...
  9. doi request reprint Current progress and future challenges in the biochemical diagnosis and treatment of pheochromocytomas and paragangliomas
    G Eisenhofer
    Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus Dresden, Germany
    Horm Metab Res 40:329-37. 2008
    ..Improvements in treatment may in the future come from several fronts, but proof of efficacy ideally will require well-coordinated multicenter prospective trials in larger numbers of patients than in previous studies...
  10. pmc Differential expression of the regulated catecholamine secretory pathway in different hereditary forms of pheochromocytoma
    Graeme Eisenhofer
    Institute of Clinical Chemistry and Laboratory Medicine, University of Dresden, Dresden, Germany
    Am J Physiol Endocrinol Metab 295:E1223-33. 2008
    ....
  11. pmc Measurements of plasma methoxytyramine, normetanephrine, and metanephrine as discriminators of different hereditary forms of pheochromocytoma
    Graeme Eisenhofer
    Institute of Clinical Chemistry and Laboratory Medicine, Department of Medicine III, University of Dresden, Dresden, Germany
    Clin Chem 57:411-20. 2011
    ..This study assessed whether measurements of plasma metanephrine, normetanephrine, and methoxytyramine, the O-methylated metabolites of catecholamines, might help to distinguish different hereditary forms of the tumor...
  12. ncbi request reprint Adverse drug reactions in patients with phaeochromocytoma: incidence, prevention and management
    Graeme Eisenhofer
    Department of Clinical Chemistry and Laboratory Medicine, University of Dresden, Dresden, Germany
    Drug Saf 30:1031-62. 2007
    ..In such cases, it is extremely important for the clinician to recognise the possibility of an underlying catecholamine-producing tumour and to take the most appropriate steps to manage and treat adverse events and clinical complications...
  13. doi request reprint Unexplained symptomatic paroxysmal hypertension in pseudopheochromocytoma: a stress response disorder?
    Graeme Eisenhofer
    Department of Medicine and Clinical Chemistry, University of Dresden, Dresden, Germany
    Ann N Y Acad Sci 1148:469-78. 2008
    ..From this pattern, one would predict that therapeutic interventions that inhibit adrenal secretion of epinephrine or block adrenoceptor-mediated responses to catecholamines might provide a logical approach to therapy...
  14. pmc Catecholamine metabolomic and secretory phenotypes in phaeochromocytoma
    Graeme Eisenhofer
    Institute of Clinical Chemistry and Laboratory Medicine, University of Dresden, 01307 Dresden, Germany
    Endocr Relat Cancer 18:97-111. 2011
    ..The data further suggest developmental origins of PPGLs from different populations of chromaffin cell progenitors...
  15. pmc Age at diagnosis of pheochromocytoma differs according to catecholamine phenotype and tumor location
    Graeme Eisenhofer
    Institute of Clinical Chemistry and Laboratory Medicine, Department of Medicine III, University of Dresden, 01307 Dresden, Germany
    J Clin Endocrinol Metab 96:375-84. 2011
    ..Pheochromocytomas and paragangliomas (PPGLs) are diagnosed earlier in patients with hereditary than sporadic disease. Whether other factors influence age at diagnosis is unclear...
  16. doi request reprint Analysis of plasma 3-methoxytyramine, normetanephrine and metanephrine by ultraperformance liquid chromatography-tandem mass spectrometry: utility for diagnosis of dopamine-producing metastatic phaeochromocytoma
    Mirko Peitzsch
    Institute of Clinical Chemistry and Laboratory Medicine, University of Dresden, Fetscherstraße 74, Dresden 01307, Germany
    Ann Clin Biochem 50:147-55. 2013
    ..Here we introduce a novel mass spectrometric based method coupled to ultraperformance liquid chromatography (LC-MS/MS) for measuring NMN, MN and 3-methoxytyramine (MTY), the O-methylated metabolite of dopamine...
  17. doi request reprint Direct effect of dehydroepiandrosterone sulfate (DHEAS) on PC-12 cell differentiation processes
    Christian G Ziegler
    Carl Gustav Carus University Hospital, Medical Clinic III, University of Dresden, Fetscherstr 74, 01307 Dresden, Germany
    Mol Cell Endocrinol 336:149-55. 2011
    ..Furthermore, employing membrane-impermeable dehydroepiandrosterone-BSA indicates the involvement of plasma-membrane bound receptors...
  18. pmc Aberrant methylation of the M-type phospholipase A(2) receptor gene in leukemic cells
    Mario Menschikowski
    Institut fur Klinische Chemie und Laboratoriumsmedizin, Technische Universitat Dresden, Fetscherstrasse 74, D 01307, Dresden, Germany
    BMC Cancer 12:576. 2012
    ..This study examined the expression and methylation of the PLA2R1 gene in Jurkat and U937 leukemic cell lines and its methylation in patients with myelodysplastic syndrome (MDS) or acute leukemia...
  19. doi request reprint Is there still a place for adrenal venous sampling in the diagnostic localization of pheochromocytoma?
    Roland Därr
    Division of Endocrinology, Diabetes, and Bone Diseases, Department of Medicine III, Dresden Technical University Medical Center, Fetscherstr 74, 01307, Dresden, Germany
    Endocrine 40:75-9. 2011
    ..This case highlights a scenario where a combination of (68)Ga-DOTATOC-PET/CT and AVS with measurement of the metanephrine to normetanephrine ratio was crucial for the preoperative assessment of a patient with bilateral pheochromocytoma...
  20. pmc Double stable isotope ultra performance liquid chromatographic-tandem mass spectrometric quantification of tissue content and activity of phenylethanolamine N-methyltransferase, the crucial enzyme responsible for synthesis of epinephrine
    Nan Qin
    Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Dresden, Dresden, Germany
    Anal Bioanal Chem 405:1713-9. 2013
    ..Development of this assay provides new possibilities for investigations focusing on regulation of PNMT, the crucial final enzyme responsible for synthesis of epinephrine, the primary fight-or-flight stress hormone...
  21. doi request reprint Levodopa therapy in Parkinson's disease: influence on liquid chromatographic tandem mass spectrometric-based measurements of plasma and urinary normetanephrine, metanephrine and methoxytyramine
    Graeme Eisenhofer
    Institute of Clinical Chemistry and Laboratory Medicine, University of Dresden, Dresden, Germany
    Ann Clin Biochem 51:38-46. 2014
    ..Levodopa, the precursor for dopamine used in the treatment of Parkinson's disease, represents one potentially interfering medication...
  22. doi request reprint Regulation of thrombomodulin expression in prostate cancer cells
    Mario Menschikowski
    Institute of Clinical Chemistry and Laboratory Medicine, Technical University of Dresden, Medical Faculty Carl Gustav Carus, Germany
    Cancer Lett 322:177-84. 2012
    ....
  23. doi request reprint Simultaneous liquid chromatography tandem mass spectrometric determination of urinary free metanephrines and catecholamines, with comparisons of free and deconjugated metabolites
    Mirko Peitzsch
    Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus at the TU Dresden, Fetscherstrasse 74, D 01307 Dresden, Germany
    Clin Chim Acta 418:50-8. 2013
    ..We introduce a novel liquid chromatographic tandem-mass spectrometric method for simultaneous measurements of urinary catecholamines and their free O-methylated metabolites, which we compare to the deconjugated metabolites...
  24. pmc Plasma-free vs deconjugated metanephrines for diagnosis of phaeochromocytoma
    Christina Pamporaki
    Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus at the TU Dresden, Fetscherstrasse 74, Dresden, Germany
    Clin Endocrinol (Oxf) 79:476-83. 2013
    ..Plasma-deconjugated normetanephrine and metanephrine have been proposed as alternative, equivalent, but easier to measure biomarkers...
  25. doi request reprint Reducing agents induce thrombomodulin shedding in human endothelial cells
    Mario Menschikowski
    Institute of Clinical Chemistry and Laboratory Medicine, Technical University of Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany
    Thromb Res 126:e88-93. 2010
    ....
  26. pmc Expression and shedding of endothelial protein C receptor in prostate cancer cells
    Mario Menschikowski
    Institute of Clinical Chemistry and Laboratory Medicine, Technical University of Dresden, Medical Faculty Carl Gustav Carus, Fetscherstrasse 74, D 01307 Dresden, Germany
    Cancer Cell Int 11:4. 2011
    ..abstract:..
  27. doi request reprint [Radiation exposure of patients during 68Ga-DOTATOC PET/CT examinations]
    H Hartmann
    Klinik und Poliklinik fur Nuklearmedizin, Universitatsklinikum Dresden, Fetscherstr 74, 01307 Dresden, Germany
    Nuklearmedizin 48:201-7. 2009
    ..Investigation of the biodistribution and calculation of dosimetry of Ga-68-DOTATOC- for patients imaged in the routine clinical setting for diagnosis or exclusion of neuroendocrine tumours...
  28. doi request reprint Differentiation of chromaffin progenitor cells to dopaminergic neurons
    Vladimir Vukicevic
    Molecular Endocrinology, Medical Clinic III, University Clinic Dresden, Dresden University of Technology, Fetscherstrasse 74, Dresden, Germany
    Cell Transplant 21:2471-86. 2012
    ..In summary, this study elucidates the capacity of chromaffin progenitor cells to generate functional dopaminergic neurons, indicating their potential use in cell replacement therapies...
  29. doi request reprint Protocol for the examination of specimens from patients with pheochromocytomas and extra-adrenal paragangliomas
    Ozgur Mete
    From the Departments of Pathology Drs Mete and Asa and Medicine Dr Ezzat, University Health Network, Toronto, Ontario, Canada the Department of Pathology, Tufts Medical Center, Boston, Massachusetts Dr Tischler the Department of Pathology, Erasmus MC University Medical Center, Rotterdam, The Netherlands Dr de Krijger the Department of Molecular and Cellular Pathology, The University of Queensland, University of Queensland Centre for Clinical Research, Royal Brisbane and Women s Hospital, Herston, Brisbane, Australia Dr McNicol the Institute of Clinical Chemistry and Laboratory Medicine and Department of Medicine III, University of Dresden, Dresden, Germany Dr Eisenhofer and the Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institutes of Health, Bethesda, Maryland Dr Pacak
    Arch Pathol Lab Med 138:182-8. 2014
    ....
  30. pmc Role of hypoxia and HIF2α in development of the sympathoadrenal cell lineage and chromaffin cell tumors with distinct catecholamine phenotypic features
    Susan Richter
    Department of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus Dresden, Dresden University of Technology, Dresden, Germany Electronic address
    Adv Pharmacol 68:285-317. 2013
    ..Moreover, current knowledge about tumor formation in cells of the sympathoadrenal lineage, leading to catecholamine-producing pheochromocytomas and paragangliomas, is analyzed in the light of the HIF2α signaling network. ..
  31. doi request reprint Succinate-to-fumarate ratio as a new metabolic marker to detect the presence of SDHB/D-related paraganglioma: initial experimental and ex vivo findings
    Nikoletta Lendvai
    Program in Reproductive and Adult Endocrinology N L, P B, K P, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 Second Department of Medicine N L, Semmelweis University, Budapest, Hungary 1088 Section on Metabolic Control Analysis R P, R L V, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Rockville, Maryland 20852 Department of Molecular Medicine P B, Institute of Virology, Slovak Academy of Sciences, Bratislava, Slovak Republic 84505 Institute of Clinical Chemistry and Laboratory Medicine G E, University Hospital Carl Gustav Carus at the TU Dresden, Dresden, Germany Department of Medicine III G E, University Hospital Carl Gustav Carus at the TU Dresden, Dresden, Germany 01307 Molecular Medicine Research Group A P, Hungarian Academy of Sciences and Semmelweis University, Budapest, Hungary and Department of Laboratory Medicine Institute A P, Central Isotope Laboratory, Semmelweis University, Budapest, Hungary 1088
    Endocrinology 155:27-32. 2014
    ....
  32. pmc Accumulation of 2-hydroxyglutarate is not a biomarker for malignant progression in IDH-mutated low-grade gliomas
    Tareq A Juratli
    Department of Neurosurgery, University Hospital Carl Gustav Carus, Dresden University of Technology, Fetscherstrasse 74, D 01307 Dresden, Germany
    Neuro Oncol 15:682-90. 2013
    ..To determine whether accumulation of 2-hydroxyglutarate in IDH-mutated low-grade gliomas (LGG; WHO grade II) correlates with their malignant transformation and to evaluate changes in metabolite levels during malignant progression...
  33. pmc Involvement of epigenetic mechanisms in the regulation of secreted phospholipase A2 expressions in Jurkat leukemia cells
    Mario Menschikowski
    Technische Universitat Dresden, Medizinische Fakultät Carl Gustav Carus, Institut fur Klinische Chemie und Laboratoriumsmedizin, Dresden, Germany
    Neoplasia 10:1195-203. 2008
    ..These data establish that regulation of sPLA(2)-IIA and sPLA(2)-V in Jurkat and other cells involves epigenetic silencing by DNA hypermethylation...
  34. doi request reprint Dehydroepiandrosterone-sulphate (DHEA-S) promotes neuroendocrine differentiation of chromaffin pheochromocytoma PC12 cells
    Alexander W Krug
    Carl Gustav Carus University Hospital, Medical Clinic III, University of Dresden, Germany
    Mol Cell Endocrinol 300:126-31. 2009
    ..Our study provides support for the notion that adrenocortical-derived DHEA-S impacts adrenomedullary chromaffin cells during development and differentiation...
  35. ncbi request reprint Biochemical diagnosis, localization and management of pheochromocytoma: focus on multiple endocrine neoplasia type 2 in relation to other hereditary syndromes and sporadic forms of the tumour
    K Pacak
    Pediatric and Reproductive Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA
    J Intern Med 257:60-8. 2005
    ..g. tumours larger than 5 cm). Laparoscopic surgery is the treatment of choice and subtotal (cortical-sparing) adrenalectomy is the procedure of choice in bilateral pheochromocytomas...
  36. ncbi request reprint Principles of catecholamine biosynthesis, metabolism and release
    C Schulz
    Department of Endocrinology and Metabolism, Otto von Guericke University, Magdeburg, Germany
    Front Horm Res 31:1-25. 2004
  37. ncbi request reprint Chromogranin a expression in phaeochromocytomas associated with von Hippel-Lindau syndrome and multiple endocrine neoplasia type 2
    S Cleary
    Clinical Neurocardiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    Horm Metab Res 39:876-83. 2007
    ..Alternatively the differences in expression in CGA and other secretory constituents may reflect downregulation of the entire regulated secretory pathway in VHL compared to MEN 2 tumours...
  38. pmc Specific genetic deficiencies of the A and B isoenzymes of monoamine oxidase are characterized by distinct neurochemical and clinical phenotypes
    J W Lenders
    Department of Medicine, Division of General Internal Medicine, St Radboud University Hospital, Nijmegen, The Netherlands
    J Clin Invest 97:1010-9. 1996
    ..The differences in neurochemical profiles indicate that, under normal conditions, MAO-A is considerably more important than MAO-B in the metabolism of biogenic amines, a factor likely to contribute to the different clinical phenotypes...
  39. ncbi request reprint Catecholamine synthesis is mediated by tyrosinase in the absence of tyrosine hydroxylase
    M Rios
    Departments of Neuroscience and Anatomy and Cell Biology, Tufts University Medical School, Boston, Massachusetts 02111, USA
    J Neurosci 19:3519-26. 1999
    ..Thus, these extraordinary circumstances reveal that tyrosinase serves as an alternative pathway to supply catecholamines...
  40. ncbi request reprint Plasma levels of catechols and metanephrines in neurogenic orthostatic hypotension
    D S Goldstein
    Clinical Neurocardiology Section, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD 20892 1620, USA
    Neurology 60:1327-32. 2003
    ..From the concept of a unitary sympathoadrenomedullary system, one might predict parallel sympathoneural and adrenomedullary abnormalities in NOH...
  41. ncbi request reprint Adrenomedullary function is severely impaired in 21-hydroxylase-deficient mice
    S R Bornstein
    Section on Endocrine Physiology, Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892
    FASEB J 13:1185-94. 1999
    ..This hitherto unrecognized mechanism may contribute to the frequent clinical, mental, and therapeutic problems encountered in humans with this genetic disease...
  42. pmc Deletion of tyrosine hydroxylase gene reveals functional interdependence of adrenocortical and chromaffin cell system in vivo
    S R Bornstein
    Pediatric and Reproductive Endocrinology Branch, National Institute of Child Health and Human Development, and National Institute of Neurological Diseases and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 97:14742-7. 2000
    ....
  43. ncbi request reprint Distinct gene expression profiles in norepinephrine- and epinephrine-producing hereditary and sporadic pheochromocytomas: activation of hypoxia-driven angiogenic pathways in von Hippel-Lindau syndrome
    G Eisenhofer
    Clinical Neurocardiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA
    Endocr Relat Cancer 11:897-911. 2004
    ....
  44. ncbi request reprint The role of neuronal and extraneuronal plasma membrane transporters in the inactivation of peripheral catecholamines
    G Eisenhofer
    Clinical Neurocardiology Section, National Institute of Neurological Disorders and Stroke, Building 10, Room 6N 252, National Institutes of Health, 10 Center Drive, MSC 1620, Bethesda, MD 20892 1620, USA
    Pharmacol Ther 91:35-62. 2001
    ..Peripheral catecholamine transporters provide important targets for clinical imaging of sympathetic nerves and diagnostic localization and treatment of neuroendocrine tumors, such as neuroblastomas and pheochromocytomas...