A K Eckstein

Summary

Country: Germany

Publications

  1. doi request reprint [Graves' orbitopathy]
    A Eckstein
    Orthoptik, Universitäts Augenklinik Essen
    Klin Monbl Augenheilkd 228:432-8. 2011
  2. doi request reprint [Update on endocrine orbitopathy]
    A Eckstein
    Zentrum für Augenheilkunde, Abteilung für Erkrankungen des vorderen Augenabschnittes, Universitatsklinikum Essen, Hufelandstr 55, 45122, Essen, Deutschland
    Ophthalmologe 110:1079-96. 2013
  3. doi request reprint Surgical treatment of Graves' ophthalmopathy
    Anja Eckstein
    University Eye Hostpital Essen, Department Neuroophthalmology, Strabism and Oculoplasics, Hufelandstrasse 55, Essen 45122, Germany
    Best Pract Res Clin Endocrinol Metab 26:339-58. 2012
  4. doi request reprint [A temporal tarsorrhaphy increases the effect of lower lid lengthening in patients with Graves' orbitopathy]
    A Eckstein
    Orthoptik, Universitäts Augenklinik Essen, Essen
    Klin Monbl Augenheilkd 228:887-91. 2011
  5. ncbi request reprint Clinical value of TSH receptor antibodies measurement in patients with Graves' orbitopathy
    A Eckstein
    Department of Ophthalmology, University Duisburg Essen, Germany
    Pediatr Endocrinol Rev 7:198-203. 2010
  6. doi request reprint [Graves' ophthalmopathy]
    A Eckstein
    Zentrum für Augenheilkunde, Universitatsklinikum, Hufelandstrasse 55, 45122, Essen, Deutschland
    Internist (Berl) 51:584, 586-8, 590-2, passim. 2010
  7. ncbi request reprint Current insights into the pathogenesis of Graves' orbitopathy
    A K Eckstein
    Endocrine Orbitopathy Research and Therapy in Essen EORT E, Centre for Ophthalmology, University Hospital Essen, Essen, Germany
    Horm Metab Res 41:456-64. 2009
  8. doi request reprint Euthyroid and primarily hypothyroid patients develop milder and significantly more asymmetrical Graves ophthalmopathy
    A K Eckstein
    Department of Ophthalmology, University of Essen, Essen, Germany
    Br J Ophthalmol 93:1052-6. 2009
  9. ncbi request reprint [Amblyopia and uveitis in childhood]
    A Eckstein
    Augenklinik, Universitatsklinikum Essen
    Klin Monbl Augenheilkd 224:507-10. 2007
  10. ncbi request reprint Dysregulation of TNF/TNFR superfamily members: a systemic link between intra- and extrathyroidal manifestations in Graves' disease
    B Quadbeck
    Division of Endocrinology, Department of Medicine, University of Duisburg Essen, Essen, Germany
    Scand J Immunol 64:523-30. 2006

Collaborators

Detail Information

Publications16

  1. doi request reprint [Graves' orbitopathy]
    A Eckstein
    Orthoptik, Universitäts Augenklinik Essen
    Klin Monbl Augenheilkd 228:432-8. 2011
    ..Smoking increases the prevalence and severity of GO and reduces the efficiency of therapy. Restoring euthyroidism leads to an improvement of GO in about 60% of the patients...
  2. doi request reprint [Update on endocrine orbitopathy]
    A Eckstein
    Zentrum für Augenheilkunde, Abteilung für Erkrankungen des vorderen Augenabschnittes, Universitatsklinikum Essen, Hufelandstr 55, 45122, Essen, Deutschland
    Ophthalmologe 110:1079-96. 2013
    ..Fortunately, defects in inactive stable Graves' orbitopathy can be successfully treated by surgery and involve decompression for proptosis reduction, muscle recession to correct diplopia and (finally) lid surgery. ..
  3. doi request reprint Surgical treatment of Graves' ophthalmopathy
    Anja Eckstein
    University Eye Hostpital Essen, Department Neuroophthalmology, Strabism and Oculoplasics, Hufelandstrasse 55, Essen 45122, Germany
    Best Pract Res Clin Endocrinol Metab 26:339-58. 2012
    ..Lid lengthening procedures are performed most often in GO patients and should be performed under local anaesthesia to get a good result. Serious complications are rare...
  4. doi request reprint [A temporal tarsorrhaphy increases the effect of lower lid lengthening in patients with Graves' orbitopathy]
    A Eckstein
    Orthoptik, Universitäts Augenklinik Essen, Essen
    Klin Monbl Augenheilkd 228:887-91. 2011
    ..The aim of this study was to compare outcomes of lower lid lengthening with and without an additional temporal tarsorrhaphy...
  5. ncbi request reprint Clinical value of TSH receptor antibodies measurement in patients with Graves' orbitopathy
    A Eckstein
    Department of Ophthalmology, University Duisburg Essen, Germany
    Pediatr Endocrinol Rev 7:198-203. 2010
    ..Definitive treatment of the thyroid can be decided early on this basis, which is an advantage for ophthalmosurgical rehabilitation...
  6. doi request reprint [Graves' ophthalmopathy]
    A Eckstein
    Zentrum für Augenheilkunde, Universitatsklinikum, Hufelandstrasse 55, 45122, Essen, Deutschland
    Internist (Berl) 51:584, 586-8, 590-2, passim. 2010
    ..Radioiodine therapy without glucocorticoids is associated with a small but significant risk (15%) of deterioration or relapse. Thyroidectomy is neutral in later stages but may improve Graves' orbitopathy in early active stages...
  7. ncbi request reprint Current insights into the pathogenesis of Graves' orbitopathy
    A K Eckstein
    Endocrine Orbitopathy Research and Therapy in Essen EORT E, Centre for Ophthalmology, University Hospital Essen, Essen, Germany
    Horm Metab Res 41:456-64. 2009
    ..To date most models have centered on provoking autoimmune responses to the TSHR, but other antigens, alone or in combination with this receptor, hopefully will succeed in inducing the full spectrum of GD...
  8. doi request reprint Euthyroid and primarily hypothyroid patients develop milder and significantly more asymmetrical Graves ophthalmopathy
    A K Eckstein
    Department of Ophthalmology, University of Essen, Essen, Germany
    Br J Ophthalmol 93:1052-6. 2009
    ..Retrospective, observational study to compare clinical symptoms and TSH-receptor antibodies (TRAb) in Graves ophthalmopathy (GO) in euthyroid and primarily hypothyroid patients to those in hyperthyroid patients...
  9. ncbi request reprint [Amblyopia and uveitis in childhood]
    A Eckstein
    Augenklinik, Universitatsklinikum Essen
    Klin Monbl Augenheilkd 224:507-10. 2007
    ..The follow-up should not only contain visual acuity measurements but also cycloplegic refraction. Especially when pupil-dilating drugs are necessary for a longer period, bifocals should be prescribed...
  10. ncbi request reprint Dysregulation of TNF/TNFR superfamily members: a systemic link between intra- and extrathyroidal manifestations in Graves' disease
    B Quadbeck
    Division of Endocrinology, Department of Medicine, University of Duisburg Essen, Essen, Germany
    Scand J Immunol 64:523-30. 2006
    ..Monocytes, therefore, may serve as a suitable target to therapeutically address the common precursor of key promoters of GD...
  11. doi request reprint The T393C polymorphism of the Galphas gene (GNAS1) is associated with the course of Graves' disease
    D Glowacka
    Department of Ophthalmology, University Hospital of Essen, University of Duisburg Essen, Germany
    Horm Metab Res 41:430-5. 2009
    ..This may allow the clinician to identify patients at risk for more severe courses of disease and to come to more timely decisions for treatment...
  12. pmc Thyroid associated ophthalmopathy: evidence for CD4(+) gammadelta T cells; de novo differentiation of RFD7(+) macrophages, but not of RFD1(+) dendritic cells; and loss of gammadelta and alphabeta T cell receptor expression
    A K Eckstein
    Department of Ophthalmology, Essen University Hospital, Essen, Germany
    Br J Ophthalmol 88:803-8. 2004
    ..To characterise periorbital immune cells (stages, kinetics) in active and inactive thyroid associated ophthalmopathy (A-TAO; I-TAO)...
  13. doi request reprint Examination of orbital tissues in murine models of Graves' disease reveals expression of UCP-1 and the TSHR in retrobulbar adipose tissues
    K T M Johnson
    Department for Ophthalmology, University of Duisburg Essen, Essen, Germany
    Horm Metab Res 45:401-7. 2013
    ..Though targets for TSHR autoimmunity could clearly be shown, immunization methods were not efficient enough to cause clear signs of orbital inflammation...
  14. doi request reprint Current insights into animal models of Graves' disease and orbitopathy
    B Wiesweg
    Center for Ophthalmology, Laboratory for Molecular Ophthalmology, University of Duisburg Essen, Essen, Germany
    Horm Metab Res 45:549-55. 2013
    ..In this review we summarize different methods used to induce murine Graves'-like disease and their impact on murine orbits. ..
  15. ncbi request reprint Maturation of thyroidal dendritic cells in Graves' disease
    B Quadbeck
    Division of Endocrinology, Department of Medicine, Uniiversity Clinic, Essen, Germany
    Scand J Immunol 55:612-20. 2002
    ..Expression of CD54 and CD83 did not significantly differ among the groups. The phenotype of intrathyroidal DC in GD thus supports their role as potential (co)stimulators of thyroid autoimmunity...
  16. pmc Impact of smoking on the response to treatment of thyroid associated ophthalmopathy
    A Eckstein
    Department of Ophthalmology, University of Essen, Germany
    Br J Ophthalmol 87:773-6. 2003
    ..The authors sought to determine if smoking also influences the course of TAO during treatment, and the efficacy of therapy...