Research Topics
| Dirk Wolfgang DrosteSummaryCountry: Germany Publications
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Detail Information
Publications
Reduction of circulating microemboli in the subclavian vein of patients undergoing haemodialysis using pre-filled instead of dry dialysersDirk W Droste
Department of Neurology, University of Munster, Germany
Nephrol Dial Transplant 18:2377-81. 2003..The objective of the present investigation was to study whether the use of pre-filled instead of dry dialysers would help to minimize the number of microemboli...
Benefit of echocontrast-enhanced transcranial color-coded duplex ultrasound in the assessment of intracranial collateral pathwaysD W Droste
Department of Neurology, University of Munster, Munster, Germany
Stroke 31:920-3. 2000..In these cases, echocontrast could be helpful to increase the diagnostic confidence or to make the diagnosis at all...
The identification of right-to-left shunts using contrast transcranial Doppler ultrasound: performance and interpretation modalities, and absence of a significant side difference of cardiac micro-emboliDirk W Droste
Departments of Neurology and Cardiology and Angiology, University of Munster, Germany
Neurol Res 26:325-30. 2004..There was no difference in microbubbles. TCD using Echovist-300 is a sensitive method to identify TEE-proven cardiac right-to-left shunts. Repetitive VM is an alternative to conventional VM...
Arterial hypertension and ischaemic strokeD W Droste
Department of Neurology, University of Munster, Germany
Acta Neurol Scand 107:241-51. 2003..Arterial hypertension is, besides age, the number one risk factor for ischaemic stroke. Patients with arterial hypertension frequently present with additional coexisting vascular risk factors interacting in a complex way...
Diffusion weighted MRI imaging and MES detection in the assessment of stroke originDirk W Droste
Department of Neurology, University of Munster, Germany
Neurol Res 29:480-4. 2007..This study compares the additional benefit of diffusion-weighted MRI (DWI) and microembolus detection by transcranial Doppler ultrasonography (TCD) in the assessment of stroke etiology...
Optimizing the technique of contrast transcranial Doppler ultrasound in the detection of right-to-left shuntsDirk W Droste
Department of Neurology, University of Munster, Munster, Germany
Stroke 33:2211-6. 2002..This article applies the modalities of these tests detailed in previous studies to a large patient cohort and compares 2 contrast agents (saline and Echovist-300)...
SonoVue (BR1), a new long-acting echocontrast agent, improves transcranial colour-coded duplex ultrasonic imagingDirk Wolfgang Droste
Department of Neurology, University of Munster, Germany
Cerebrovasc Dis 14:27-32. 2002..SonoVue (BR1) is a new, long-acting echocontrast agent, which could be helpful in these instances...
Contrast transcranial Doppler ultrasound in the detection of right-to-left shunts: comparison of Echovist-200 and Echovist-300, timing of the Valsalva maneuver, and general recommendations for the performance of the testDirk W Droste
Department of Neurology, University of Munster, Munster, Germany
Cerebrovasc Dis 13:235-41. 2002..Both Echovist preparations are in use. Currently, the appropriate timing of the VM is still under debate...
Detection of microemboli in the subclavian vein of patients undergoing haemodialysis and haemodiafiltration using pulsed Doppler ultrasoundDirk W Droste
Department of Neurology and Department of Internal Medicine, University of Munster, Munster, Germany
Nephrol Dial Transplant 17:462-6. 2002..The pathophysiology leading to pulmonary side effects during haemodialysis and haemodiafiltration is not yet fully understood. Chronic microembolization, which can be demonstrated by pulsed Doppler ultrasound, may be one cause...
Clinical utility of contrast-enhanced ultrasound in neurosonologyDirk W Droste
Department of Neurology, University of Munster, Munster, Germany
Eur Neurol 59:2-8. 2008..Such agents have a relatively long-lasting effect (up to 7 min), and can be administered as a single injection or, alternatively, a fractionated injection protocol can be used, depending on the quality of the window...
Evaluation of progression and spread of atherothrombosisDirk W Droste
Department of Neurology, University of Munster, Germany
Cerebrovasc Dis 13:7-11. 2002..The generalized nature of atherothrombosis and the methods for evaluating the spread of disease are illustrated through the case history of a patient with disseminated atherothrombotic disease...
Clinically silent circulating microemboli in 20 patients with carotid or vertebral artery dissectionD W Droste
Department of Neurology, University of Munster, Germany
Cerebrovasc Dis 12:181-5. 2001..Detection of clinically silent circulating microemboli by transcranial Doppler sonography (TCD) is now widely investigated in patients with carotid artery disease in the hope to identify patients at increased risk for stroke...
Right-to-left-shunts detected by transesophageal echocardiography and transcranial Doppler sonographyDirk W Droste
Department of Neurology, University of Munster, Germany
Cerebrovasc Dis 17:191-6. 2004..Transesophageal echocardiography (TEE) and transcranial Doppler sonography (TCD) can identify right-to-left-shunts that predispose to paradoxical embolism. In a large cohort we compared the results of both techniques...
The use of embolic signal detection in multicenter trials to evaluate antiplatelet efficacy: signal analysis and quality control mechanisms in the CARESS (Clopidogrel and Aspirin for Reduction of Emboli in Symptomatic carotid Stenosis) trialRalf Dittrich
Department of Neurology, , Germany
Stroke 37:1065-9. 2006..84; P<0.001). CONCLUSIONS: Multicenter studies using MES as outcome parameter are feasible. However, primary and secondary quality control procedures are important...
Benefit of echocontrast-enhanced transcranial arterial color-coded duplex ultrasoundDirk W Droste
Department of Neurology, University of Munster, Germany
Cerebrovasc Dis 20:332-6. 2005..In these cases, echocontrast could be helpful to increase the diagnostic confidence or to make the diagnosis at all...
Microembolus detection in four patients with Fabry's disease: further support for a primarily microangiopathic origin of early cerebrovascular symptomsMartin Ritter
Department of Neurology, Universitatsklinikum Munster, Munster, Germany
Eur Neurol 50:141-5. 2003....
Microembolic signals on transcranial Doppler ultrasound are correlated with platelet activation markers, but not with platelet-leukocyte associates: a study in patients with acute stroke and in patients with asymptomatic carotid stenosisMartin A Ritter
Department of Neurology, Experimental and Clinical Hemostasis, University of Munster, Munster, Germany
Neurol Res 31:11-6. 2009..The in vivo correlates of microembolic signals (MES) are still unknown. Platelet-associates (PA) with monocytes or granulocytes or platelet aggregates only may represent these correlates...
Treatment options in vertebrobasilar dolichoectasia--case report and review of the literatureRainer Dziewasa
Department of Neurology, , , Germany
Eur Neurol 49:245-7. 2003
Therapy of Sneddon syndromeAgnes Floel
Department of Neurology, University of Munster, Munster, Germany
Eur Neurol 48:126-32. 2002..Therapeutic options in SNS in both aPL-positive and aPL-negative patients with SNS are discussed...
On the origin of microembolic signals--a clinical and postmortem studyGernot Schulte-Altedorneburg
Department of Neurology, , Germany
J Neurol 250:1044-9. 2003..The finding of MES justifies an extensive clinical and laboratory search for potential embolic sources including extracranial and intracranial colour-coded duplex ultrasound, ECG, Holter-ECG, and TEE...
Platelets in patients with acute ischemic stroke are exhausted and refractory to thrombin, due to cleavage of the seven-transmembrane thrombin receptor (PAR-1)Kerstin Jurk
Department of Anaesthesiology and Intensive Care, Experimental and Clinical Haemostasis, University Hospital of Munster, Munster, Germany
Thromb Haemost 91:334-44. 2004..Platelets from patients with acute cerebral ischemia are exhausted and desensitized to thrombin through cleavage of PAR-1, indicating that high concentrations of thrombin occur with acute cerebrovascular ischemic events in vivo...
Comparison of a 1-MHz and a 2-MHz probe for microembolus detection using transcranial Doppler ultrasoundDirk W Droste
Department of Neurology, University of Munster, Germany
Neurol Res 27:471-6. 2005..Moreover, embolus detection by transcranial Doppler ultrasound is very time consuming and semi-automated detection is mandatory. Therefore, we studied an on-line algorithm using the bi-gate technique and the two transmission frequencies...
Microembolus detection by transcranial doppler sonographyRalf Dittrich
Klinik und Poliklinik fur Neurologie, Universitatsklinikum Munster, Albert Schweitzer Str 33, D 48129, Munster, Germany
Eur J Ultrasound 16:21-30. 2002..This article provides a review of the actual literature concerning the current state of technical and clinical aspects of microembolus detection...
Circulating microemboli in 33 patients with intracranial arterial stenosisDirk W Droste
Department of Neurology, , Germany
Cerebrovasc Dis 13:26-30. 2002..Therapeutic anticoagulation was not sufficient to suppress microemboli formation...
