E Koch

Summary

Affiliation: Dr. Willmar Schwabe GmbH and Co. KG
Country: Germany

Publications

  1. ncbi request reprint [The results of experimental and clinical studies. Cardio- and vasoprotective actions of standardized Crataegus extract]
    Egon Koch
    Dr Willmar Schwabe GmbH and Co KG, Abteilungen für Pharmakologie und Klinische Forschung, Karlsruhe
    Pharm Unserer Zeit 34:52-7. 2005
  2. ncbi request reprint In vitro evaluation of the cytotoxic potential of alkylphenols from Ginkgo biloba L
    Helke Hecker
    Institute of Experimental and Clinical Pharmacology and Toxicology, Medical University of Lubeck, Ratzeburger Alle 160, Lubeck, Germany
    Toxicology 177:167-77. 2002
  3. ncbi request reprint Pharmacological profile of extracts of Pelargonium sidoides and their constituents
    Herbert Kolodziej
    Institut fur Pharmazie, Pharmazeutische Biologie, Freie Universitat Berlin, Berlin, Germany
    Phytomedicine 10:18-24. 2003
  4. ncbi request reprint Inhibition of platelet activating factor (PAF)-induced aggregation of human thrombocytes by ginkgolides: considerations on possible bleeding complications after oral intake of Ginkgo biloba extracts
    E Koch
    Department of Pharmacology, Dr Willmar Schwabe GmbH and Co KG, Pharmaceuticals, Karlsruhe, Germany
    Phytomedicine 12:10-6. 2005
  5. ncbi request reprint Influence of the Ginkgo extract EGb 761 on rat liver cytochrome P450 and steroid metabolism and excretion in rats and man
    Shyam S Chatterjee
    Dr Willmar Schwabe Pharmaceuticals, Willmar Schwabe Str 4, 76227 Karlsruhe, Germany
    J Pharm Pharmacol 57:641-50. 2005
  6. ncbi request reprint Evidence for immunotoxic effects of crude Ginkgo biloba L. leaf extracts using the popliteal lymph node assay in the mouse
    E Koch
    Department of Pharmacology and Department of Natural Product Chemistry, Dr Willmar Schwabe GmbH and Co, Arzneimittel, 76209, Karlsruhe, Germany
    Int J Immunopharmacol 22:229-36. 2000
  7. ncbi request reprint Treatment of rats with the Pelargonium sidoides extract EPs 7630 has no effect on blood coagulation parameters or on the pharmacokinetics of warfarin
    E Koch
    Preclinical Research, Dr Willmar Schwabe GmbH and Co KG, Karlsruhe, Germany
    Phytomedicine 14:40-5. 2007
  8. doi request reprint Standardized extracts from hawthorn leaves and flowers in the treatment of cardiovascular disorders--preclinical and clinical studies
    Egon Koch
    Preclinical Research, Dr Willmar Schwabe GmbH and Co KG, Karlsruhe, Germany
    Planta Med 77:1123-8. 2011
  9. ncbi request reprint Extracts from fruits of saw palmetto (Sabal serrulata) and roots of stinging nettle (Urtica dioica): viable alternatives in the medical treatment of benign prostatic hyperplasia and associated lower urinary tracts symptoms
    E Koch
    Department of Pharmacology, Dr Willmar Schwabe Arzneimittel GmbH, Karlsruhe, Germany
    Planta Med 67:489-500. 2001
  10. ncbi request reprint Crataegus special extract WS 1442 improves cardiac function and reduces infarct size in a rat model of prolonged coronary ischemia and reperfusion
    Maris Veveris
    Department of Medicinal Chemistry, Latvian Institute of Organic Synthesis, Riga, Latvia
    Life Sci 74:1945-55. 2004

Collaborators

Detail Information

Publications11

  1. ncbi request reprint [The results of experimental and clinical studies. Cardio- and vasoprotective actions of standardized Crataegus extract]
    Egon Koch
    Dr Willmar Schwabe GmbH and Co KG, Abteilungen für Pharmakologie und Klinische Forschung, Karlsruhe
    Pharm Unserer Zeit 34:52-7. 2005
  2. ncbi request reprint In vitro evaluation of the cytotoxic potential of alkylphenols from Ginkgo biloba L
    Helke Hecker
    Institute of Experimental and Clinical Pharmacology and Toxicology, Medical University of Lubeck, Ratzeburger Alle 160, Lubeck, Germany
    Toxicology 177:167-77. 2002
    ....
  3. ncbi request reprint Pharmacological profile of extracts of Pelargonium sidoides and their constituents
    Herbert Kolodziej
    Institut fur Pharmazie, Pharmazeutische Biologie, Freie Universitat Berlin, Berlin, Germany
    Phytomedicine 10:18-24. 2003
    ..The present results, when taken together with the recently reported pharmacological activities, provide for a rationale basis of the utilization of EPs 7630 in the treatment of respiratory tract infections...
  4. ncbi request reprint Inhibition of platelet activating factor (PAF)-induced aggregation of human thrombocytes by ginkgolides: considerations on possible bleeding complications after oral intake of Ginkgo biloba extracts
    E Koch
    Department of Pharmacology, Dr Willmar Schwabe GmbH and Co KG, Pharmaceuticals, Karlsruhe, Germany
    Phytomedicine 12:10-6. 2005
    ....
  5. ncbi request reprint Influence of the Ginkgo extract EGb 761 on rat liver cytochrome P450 and steroid metabolism and excretion in rats and man
    Shyam S Chatterjee
    Dr Willmar Schwabe Pharmaceuticals, Willmar Schwabe Str 4, 76227 Karlsruhe, Germany
    J Pharm Pharmacol 57:641-50. 2005
    ..These results indicate that the effects of EGb 761 on drug metabolising enzymes are specific for rats and may not be extrapolated to man...
  6. ncbi request reprint Evidence for immunotoxic effects of crude Ginkgo biloba L. leaf extracts using the popliteal lymph node assay in the mouse
    E Koch
    Department of Pharmacology and Department of Natural Product Chemistry, Dr Willmar Schwabe GmbH and Co, Arzneimittel, 76209, Karlsruhe, Germany
    Int J Immunopharmacol 22:229-36. 2000
    ..The PLNA appears to represent a simple test model for the detection, characterisation and control of ingredients with potential immunotoxic side effects in complex herbal drugs...
  7. ncbi request reprint Treatment of rats with the Pelargonium sidoides extract EPs 7630 has no effect on blood coagulation parameters or on the pharmacokinetics of warfarin
    E Koch
    Preclinical Research, Dr Willmar Schwabe GmbH and Co KG, Karlsruhe, Germany
    Phytomedicine 14:40-5. 2007
    ....
  8. doi request reprint Standardized extracts from hawthorn leaves and flowers in the treatment of cardiovascular disorders--preclinical and clinical studies
    Egon Koch
    Preclinical Research, Dr Willmar Schwabe GmbH and Co KG, Karlsruhe, Germany
    Planta Med 77:1123-8. 2011
    ..In this review the pharmacological and clinical data relating to these standardized extracts are summarized...
  9. ncbi request reprint Extracts from fruits of saw palmetto (Sabal serrulata) and roots of stinging nettle (Urtica dioica): viable alternatives in the medical treatment of benign prostatic hyperplasia and associated lower urinary tracts symptoms
    E Koch
    Department of Pharmacology, Dr Willmar Schwabe Arzneimittel GmbH, Karlsruhe, Germany
    Planta Med 67:489-500. 2001
    ..These investigations have not only broadened the scientific basis for the rational use of phytotherapeutics but have also provided evidence for their therapeutic efficacy and favourable safety profile...
  10. ncbi request reprint Crataegus special extract WS 1442 improves cardiac function and reduces infarct size in a rat model of prolonged coronary ischemia and reperfusion
    Maris Veveris
    Department of Medicinal Chemistry, Latvian Institute of Organic Synthesis, Riga, Latvia
    Life Sci 74:1945-55. 2004
    ..4 +/- 2.6%). It is suggested that these pharmacological effects are accounted for by the combined antioxidative, leukocyte elastase inhibiting and endothelial nitric oxide (NO) synthesis enhancing properties of WS 1442...
  11. ncbi request reprint Proteome analysis reveals a distinct molecular profile of cellular stress following incubation of DDT1-MF2 smooth muscle cells in the presence of a high concentration of hyperforin
    Andre Schrattenholz
    ProteoSys AG, Mainz, Germany
    Planta Med 70:342-6. 2004
    ....