Klaus Peter Dieckmann

Summary

Country: Germany

Publications

  1. Dieckmann K, Gehrckens R. Thrombosis of abdominal aorta during cisplatin-based chemotherapy of testicular seminoma - a case report. BMC Cancer. 2009;9:459 pubmed publisher
    ..This is the first case of endo-aortic thrombosis during chemotherapy for testicular germ cell cancer. Providers of chemotherapy must be aware of arterial thrombosis even in young patients with testicular cancer. ..
  2. request reprint
    Dieckmann K, Struss W, Budde U. Evidence for acute vascular toxicity of cisplatin-based chemotherapy in patients with germ cell tumour. Anticancer Res. 2011;31:4501-5 pubmed
    ..Long-term vascular complications of chemotherapy appear to be different, pathogenetically. ..
  3. Dieckmann K, Dralle Filiz I, Matthies C, Heinzelbecker J, Bedke J, Ellinger J, et al. Testicular seminoma clinical stage 1: treatment outcome on a routine care level. J Cancer Res Clin Oncol. 2016;142:1599-607 pubmed publisher
    ..Importantly, one course Carboplatin involved low efficacy to control the disease in large tumors. ..
  4. Dieckmann K, Radtke A, Spiekermann M, Balks T, Matthies C, Becker P, et al. Serum Levels of MicroRNA miR-371a-3p: A Sensitive and Specific New Biomarker for Germ Cell Tumours. Eur Urol. 2017;71:213-220 pubmed publisher
    ..7% of patients and thus is far more sensitive and specific than classical serum markers. It correlates with tumour burden and treatment results. Validation in a large patient cohort is needed. ..
  5. request reprint
    Dieckmann K, Endsin G, Pichlmeier U. How valid is the prenatal estrogen excess hypothesis of testicular germ cell cancer? A case control study on hormone-related factors. Eur Urol. 2001;40:677-83; discussion 684 pubmed
    ..But, assessing the negative results of this study in light of equally negative results in previous investigations, the estrogen excess hypothesis still remains to be hypothetic. ..
  6. request reprint
    Dieckmann K, Henke R, Ovenbeck R. Renal actinomycosis mimicking renal carcinoma. Eur Urol. 2001;39:357-9 pubmed
    ..As nephrectomy may prove hazardous in these cases, the diagnosis should be attempted pre-operatively by ultrasound-guided aspiration and consecutive antibiotic treatment. In selected cases surgery could be avoided at all...
  7. request reprint
    Dieckmann K, Lauke H, Michl U, Winter E, Loy V. Testicular germ cell cancer despite previous local radiotherapy to the testis. Eur Urol. 2002;41:643-9; discussion 649-50 pubmed
    ..Other explanations, though less probable, could be technical radiotherapeutic failure due to targeting problems and a pre-existing radioresistent germ cell tumour in the irradiated testicle. ..
  8. request reprint
    Dieckmann K, Loy V. False-negative biopsies for the diagnosis of testicular intraepithelial neoplasia (TIN)--an update. Eur Urol. 2003;43:516-21 pubmed
    ..Two-site biopsies would probably increase the accuracy of the biopsy in high risk cases. ..
  9. request reprint
    Dieckmann K, Pichlmeier U. Clinical epidemiology of testicular germ cell tumors. World J Urol. 2004;22:2-14 pubmed
    ..Thus, the sum of evidence corresponds to level III b. This concept is appealing because it would explain several hitherto unexplained epidemiological features of GCT. ..
  10. request reprint
    Dieckmann K, Albers P, Classen J, de Wit M, Pichlmeier U, Rick O, et al. Late relapse of testicular germ cell neoplasms: a descriptive analysis of 122 cases. J Urol. 2005;173:824-9 pubmed
    ..These latter subgroups should be followed with annual health examinations for at least 10 years. ..

Locale

Detail Information

Publications15

  1. Dieckmann K, Gehrckens R. Thrombosis of abdominal aorta during cisplatin-based chemotherapy of testicular seminoma - a case report. BMC Cancer. 2009;9:459 pubmed publisher
    ..This is the first case of endo-aortic thrombosis during chemotherapy for testicular germ cell cancer. Providers of chemotherapy must be aware of arterial thrombosis even in young patients with testicular cancer. ..
  2. request reprint
    Dieckmann K, Struss W, Budde U. Evidence for acute vascular toxicity of cisplatin-based chemotherapy in patients with germ cell tumour. Anticancer Res. 2011;31:4501-5 pubmed
    ..Long-term vascular complications of chemotherapy appear to be different, pathogenetically. ..
  3. Dieckmann K, Dralle Filiz I, Matthies C, Heinzelbecker J, Bedke J, Ellinger J, et al. Testicular seminoma clinical stage 1: treatment outcome on a routine care level. J Cancer Res Clin Oncol. 2016;142:1599-607 pubmed publisher
    ..Importantly, one course Carboplatin involved low efficacy to control the disease in large tumors. ..
  4. Dieckmann K, Radtke A, Spiekermann M, Balks T, Matthies C, Becker P, et al. Serum Levels of MicroRNA miR-371a-3p: A Sensitive and Specific New Biomarker for Germ Cell Tumours. Eur Urol. 2017;71:213-220 pubmed publisher
    ..7% of patients and thus is far more sensitive and specific than classical serum markers. It correlates with tumour burden and treatment results. Validation in a large patient cohort is needed. ..
  5. request reprint
    Dieckmann K, Endsin G, Pichlmeier U. How valid is the prenatal estrogen excess hypothesis of testicular germ cell cancer? A case control study on hormone-related factors. Eur Urol. 2001;40:677-83; discussion 684 pubmed
    ..But, assessing the negative results of this study in light of equally negative results in previous investigations, the estrogen excess hypothesis still remains to be hypothetic. ..
  6. request reprint
    Dieckmann K, Henke R, Ovenbeck R. Renal actinomycosis mimicking renal carcinoma. Eur Urol. 2001;39:357-9 pubmed
    ..As nephrectomy may prove hazardous in these cases, the diagnosis should be attempted pre-operatively by ultrasound-guided aspiration and consecutive antibiotic treatment. In selected cases surgery could be avoided at all...
  7. request reprint
    Dieckmann K, Lauke H, Michl U, Winter E, Loy V. Testicular germ cell cancer despite previous local radiotherapy to the testis. Eur Urol. 2002;41:643-9; discussion 649-50 pubmed
    ..Other explanations, though less probable, could be technical radiotherapeutic failure due to targeting problems and a pre-existing radioresistent germ cell tumour in the irradiated testicle. ..
  8. request reprint
    Dieckmann K, Loy V. False-negative biopsies for the diagnosis of testicular intraepithelial neoplasia (TIN)--an update. Eur Urol. 2003;43:516-21 pubmed
    ..Two-site biopsies would probably increase the accuracy of the biopsy in high risk cases. ..
  9. request reprint
    Dieckmann K, Pichlmeier U. Clinical epidemiology of testicular germ cell tumors. World J Urol. 2004;22:2-14 pubmed
    ..Thus, the sum of evidence corresponds to level III b. This concept is appealing because it would explain several hitherto unexplained epidemiological features of GCT. ..
  10. request reprint
    Dieckmann K, Albers P, Classen J, de Wit M, Pichlmeier U, Rick O, et al. Late relapse of testicular germ cell neoplasms: a descriptive analysis of 122 cases. J Urol. 2005;173:824-9 pubmed
    ..These latter subgroups should be followed with annual health examinations for at least 10 years. ..
  11. request reprint
    Dieckmann K, Kulejewski M, Pichlmeier U, Loy V. Diagnosis of contralateral testicular intraepithelial neoplasia (TIN) in patients with testicular germ cell cancer: systematic two-site biopsies are more sensitive than a single random biopsy. Eur Urol. 2007;51:175-83; discussion 183-5 pubmed
    ..The diagnostic extra yield imparted by double biopsies is 18%. Discordant results regarding TIN are predominantly encountered in normal-sized testicles. The new standard in diagnosing TIN is two-site biopsy. ..
  12. Dieckmann K, Hartmann J, Classen J, Lüdde R, Diederichs M, Pichlmeier U. Tallness is associated with risk of testicular cancer: evidence for the nutrition hypothesis. Br J Cancer. 2008;99:1517-21 pubmed publisher
    ..This study expands the current view of GCT tumorigenesis by suggesting that high-calorie intake in childhood promotes GCT precursors originating in utero. ..
  13. Dieckmann K, Hartmann J, Classen J, Diederichs M, Pichlmeier U. Is increased body mass index associated with the incidence of testicular germ cell cancer?. J Cancer Res Clin Oncol. 2009;135:731-8 pubmed publisher
    ....
  14. Dieckmann K, Kulejewski M, Heinemann V, Loy V. Testicular biopsy for early cancer detection--objectives, technique and controversies. Int J Androl. 2011;34:e7-13 pubmed publisher
    ..Further candidates for biopsy are selected patients with sonographic testicular microlithiasis. Despite its usefulness, the procedure has been implemented in clinical routine only in few countries thus far...
  15. Dieckmann K, Wilken S, Loy V, Matthies C, Kleinschmidt K, Bedke J, et al. Treatment of testicular intraepithelial neoplasia (intratubular germ cell neoplasia unspecified) with local radiotherapy or with platinum-based chemotherapy: a survey of the German Testicular Cancer Study Group. Ann Oncol. 2013;24:1332-7 pubmed publisher
    ..The treatment of testicular intraepithelial neoplasia (TIN), the progenitor of testicular germ cell tumours (GCTs), is based on little data...