A Schomig

Summary

Affiliation: Deutsches Herzzentrum
Country: Germany

Publications

  1. ncbi request reprint A randomized trial of coronary stenting versus balloon angioplasty as a rescue intervention after failed thrombolysis in patients with acute myocardial infarction
    Albert Schomig
    Deutsches Herzzentrum, Medizinische Klinik rechts der Isar, Technische Universitat, Munich, Germany
    J Am Coll Cardiol 44:2073-9. 2004
  2. ncbi request reprint A meta-analysis of 16 randomized trials of sirolimus-eluting stents versus paclitaxel-eluting stents in patients with coronary artery disease
    Albert Schomig
    Deutsches Herzzentrum, Technische Universitat, Munich, Germany
    J Am Coll Cardiol 50:1373-80. 2007
  3. ncbi request reprint Mechanical reperfusion in patients with acute myocardial infarction presenting more than 12 hours from symptom onset: a randomized controlled trial
    Albert Schomig
    Deutsches Herzzentrum, 1 Medizinische Klinik rechts der Isar, Technische Universitat, Munich, Germany
    JAMA 293:2865-72. 2005
  4. ncbi request reprint One year outcomes with abciximab vs. placebo during percutaneous coronary intervention after pre-treatment with clopidogrel
    Albert Schomig
    Deutsches Herzzentrum, Lazarettstr 36, 80636 Munich, Germany
    Eur Heart J 26:1379-84. 2005
  5. ncbi request reprint Statin treatment following coronary artery stenting and one-year survival
    Albert Schomig
    Deutsches Herzzentrum and 1 Medizinische Klinik rechts der Isar, Technische Universitat, Munich, Germany
    J Am Coll Cardiol 40:854-61. 2002
  6. ncbi request reprint Coronary stenting plus platelet glycoprotein IIb/IIIa blockade compared with tissue plasminogen activator in acute myocardial infarction. Stent versus Thrombolysis for Occluded Coronary Arteries in Patients with Acute Myocardial Infarction Study Investiga
    A Schomig
    Deutsches Herzzentrum, 1 Medizinische Klinik rechts der Isar, Munich, Germany
    N Engl J Med 343:385-91. 2000
  7. doi request reprint A meta-analysis of 17 randomized trials of a percutaneous coronary intervention-based strategy in patients with stable coronary artery disease
    Albert Schomig
    Deutsches Herzzentrum Munchen, Technische Universitat, Munich, Germany
    J Am Coll Cardiol 52:894-904. 2008
  8. ncbi request reprint Late myocardial salvage: time to recognize its reality in the reperfusion therapy of acute myocardial infarction
    Albert Schomig
    Deutsches Herzzentrum, Technische Universitat, Lazarettstrasse 36, Munich, Germany
    Eur Heart J 27:1900-7. 2006
  9. ncbi request reprint Therapy-dependent influence of time-to-treatment interval on myocardial salvage in patients with acute myocardial infarction treated with coronary artery stenting or thrombolysis
    Albert Schomig
    Deutsches Herzzentrum and 1 Medizinische Klinik rechts der Isar, Munchen, Germany
    Circulation 108:1084-8. 2003
  10. doi request reprint Antiplatelet effects of clopidogrel and bleeding in patients undergoing coronary stent placement
    D Sibbing
    Deutsches Herzzentrum München and I Medizinische Klinik, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
    J Thromb Haemost 8:250-6. 2010

Collaborators

Detail Information

Publications206 found, 100 shown here

  1. ncbi request reprint A randomized trial of coronary stenting versus balloon angioplasty as a rescue intervention after failed thrombolysis in patients with acute myocardial infarction
    Albert Schomig
    Deutsches Herzzentrum, Medizinische Klinik rechts der Isar, Technische Universitat, Munich, Germany
    J Am Coll Cardiol 44:2073-9. 2004
    ..This study was conducted to assess whether coronary stenting produces better results compared with balloon angioplasty in patients with acute myocardial infarction (AMI) after failed thrombolysis...
  2. ncbi request reprint A meta-analysis of 16 randomized trials of sirolimus-eluting stents versus paclitaxel-eluting stents in patients with coronary artery disease
    Albert Schomig
    Deutsches Herzzentrum, Technische Universitat, Munich, Germany
    J Am Coll Cardiol 50:1373-80. 2007
    ..Our purpose was to make a synthesis of the available evidence on the relative efficacy and safety of 2 drug-eluting stents (DES)--sirolimus-eluting stent (SES) and paclitaxel-eluting stent (PES)--in patients with coronary artery disease...
  3. ncbi request reprint Mechanical reperfusion in patients with acute myocardial infarction presenting more than 12 hours from symptom onset: a randomized controlled trial
    Albert Schomig
    Deutsches Herzzentrum, 1 Medizinische Klinik rechts der Isar, Technische Universitat, Munich, Germany
    JAMA 293:2865-72. 2005
    ..Current guidelines do not recommend reperfusion treatment in these patients...
  4. ncbi request reprint One year outcomes with abciximab vs. placebo during percutaneous coronary intervention after pre-treatment with clopidogrel
    Albert Schomig
    Deutsches Herzzentrum, Lazarettstr 36, 80636 Munich, Germany
    Eur Heart J 26:1379-84. 2005
    ..We assessed whether there was any clinical benefit from abciximab at 1 year follow-up...
  5. ncbi request reprint Statin treatment following coronary artery stenting and one-year survival
    Albert Schomig
    Deutsches Herzzentrum and 1 Medizinische Klinik rechts der Isar, Technische Universitat, Munich, Germany
    J Am Coll Cardiol 40:854-61. 2002
    ..We assessed the influence of statin therapy given after the procedure on one-year survival of patients treated with coronary artery stenting...
  6. ncbi request reprint Coronary stenting plus platelet glycoprotein IIb/IIIa blockade compared with tissue plasminogen activator in acute myocardial infarction. Stent versus Thrombolysis for Occluded Coronary Arteries in Patients with Acute Myocardial Infarction Study Investiga
    A Schomig
    Deutsches Herzzentrum, 1 Medizinische Klinik rechts der Isar, Munich, Germany
    N Engl J Med 343:385-91. 2000
    ....
  7. doi request reprint A meta-analysis of 17 randomized trials of a percutaneous coronary intervention-based strategy in patients with stable coronary artery disease
    Albert Schomig
    Deutsches Herzzentrum Munchen, Technische Universitat, Munich, Germany
    J Am Coll Cardiol 52:894-904. 2008
    ..This study assessed the impact on long-term mortality of percutaneous coronary intervention (PCI) versus medical treatment in patients with symptoms or signs of myocardial ischemia but no acute coronary syndrome...
  8. ncbi request reprint Late myocardial salvage: time to recognize its reality in the reperfusion therapy of acute myocardial infarction
    Albert Schomig
    Deutsches Herzzentrum, Technische Universitat, Lazarettstrasse 36, Munich, Germany
    Eur Heart J 27:1900-7. 2006
    ..Instead, we strongly recommend the primary PCI in patients with AMI presenting late after onset of myocardial ischaemia...
  9. ncbi request reprint Therapy-dependent influence of time-to-treatment interval on myocardial salvage in patients with acute myocardial infarction treated with coronary artery stenting or thrombolysis
    Albert Schomig
    Deutsches Herzzentrum and 1 Medizinische Klinik rechts der Isar, Munchen, Germany
    Circulation 108:1084-8. 2003
    ..The relationship between myocardial salvage and time-to-treatment interval in patients with acute myocardial infarction (AMI) treated with coronary artery stenting or thrombolysis has not been studied...
  10. doi request reprint Antiplatelet effects of clopidogrel and bleeding in patients undergoing coronary stent placement
    D Sibbing
    Deutsches Herzzentrum München and I Medizinische Klinik, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
    J Thromb Haemost 8:250-6. 2010
    ..In patients undergoing percutaneous coronary intervention (PCI), a link between bleeding and excess mortality has been demonstrated. A potential association of platelet response to clopidogrel and bleeding has not been well established yet...
  11. ncbi request reprint Glycoprotein Ia gene C807T polymorphism and risk for major adverse cardiac events within the first 30 days after coronary artery stenting
    N von Beckerath
    Deutsches Herzzentrum and 1 Medizinische Klinik rechts der Isar, Technische Universitat Munchen, Munich, Germany
    Blood 95:3297-301. 2000
    ..15 (0.76-1.75). Therefore, C807T genotype has no significant influence on the major adverse events occurring after coronary artery stenting...
  12. ncbi request reprint PlA polymorphism of glycoprotein IIIa and risk of adverse events after coronary stent placement
    A Kastrati
    Deutsches Herzzentrum and 1 Medizinische Klinik rechts der Isar, Technische Universitat Munchen, Munich, Germany
    J Am Coll Cardiol 36:84-9. 2000
    ..We designed this prospective study to test the hypothesis that platelet antigen (PlA) polymorphism of glycoprotein (GP) IIIa is associated with an increased risk for adverse events after coronary stent placement...
  13. ncbi request reprint G protein beta3 subunit polymorphism and risk of thrombosis and restenosis following coronary stent placement
    N von Beckerath
    Deutsches Herzzentrum München and 1 Medizinische Klinik rechts der Isar, Technische Universitat Munchen, Lazarettstr 36, 80636, Munich, Germany
    Atherosclerosis 149:151-5. 2000
    ..4% CC, 44.6% CT, 10.0% TT; P = 0.644). In conclusion, C825T polymorphism has no appreciable impact on the mechanisms leading to thrombosis and restenosis following coronary stent placement...
  14. ncbi request reprint PlA polymorphism of platelet glycoprotein IIIa and risk of restenosis after coronary stent placement
    A Kastrati
    Deutsches Herzzentrum and 1 Medizinische Klinik rechts der Isar, Technische Universitat Munchen, Munich, Germany
    Circulation 99:1005-10. 1999
    ..We designed this prospective study to test the hypothesis that PlA polymorphism of glycoprotein IIIa is associated with an increased risk for restenosis after coronary stent placement...
  15. ncbi request reprint Effect of glycoprotein IIb/IIIa receptor blockade with abciximab on clinical and angiographic restenosis rate after the placement of coronary stents following acute myocardial infarction
    F J Neumann
    Deutsches Herzzentrum und 1 Medizinische Klinik der Technischen Universität München, Munich, Germany
    J Am Coll Cardiol 35:915-21. 2000
    ..We also intended to assess the impact of abciximab on clinical outcome in this setting...
  16. ncbi request reprint Intracoronary stenting and angiographic results: strut thickness effect on restenosis outcome (ISAR-STEREO) trial
    A Kastrati
    Deutsches Herzzentrum, Munich, Germany
    Circulation 103:2816-21. 2001
    ..The objective of this randomized, multicenter study was to assess whether a reduced strut thickness of coronary stents is associated with improved follow-up angiographic and clinical results...
  17. ncbi request reprint Sustained benefit over four years from an initial combined antiplatelet regimen after coronary stent placement in the ISAR trial. Intracoronary Stenting and Antithrombotic Regimen
    H Schuhlen
    I Medizinische Klinik rechts der Isar and Deutsches Herzzentrum München, München Technische Universität, Munich, Germany
    Am J Cardiol 87:397-400. 2001
    ..6%; p = 0.50). This study shows that the benefit of combined antiplatelet therapy evident after 30 days is maintained after 4 years. Independent of the initial regimen, rates of adverse cardiac events are low beyond the first year...
  18. ncbi request reprint Effect of glycoprotein IIb/IIIa receptor blockade on platelet-leukocyte interaction and surface expression of the leukocyte integrin Mac-1 in acute myocardial infarction
    F J Neumann
    Deutsches Herzzentrum and 1 Medizinische Klinik der Technischen Universität München, Munich, Germany
    J Am Coll Cardiol 34:1420-6. 1999
    ..This prospective randomized study investigated platelet-induced upregulation of Mac-1 on monocytes and its inhibition by glycoprotein (GP) IIb/IIIa blockage in patients with acute myocardial infarction (AMI)...
  19. ncbi request reprint Antiplatelet effect of ticlopidine after coronary stenting
    F J Neumann
    Deutsches Herzzentrum und 1 Medizinische Klinik der Technischen Universität München, Munich, Germany
    J Am Coll Cardiol 29:1515-9. 1997
    ..This study sought to investigate the contribution of ticlopidine to the inhibition of platelet activation after coronary stent placement...
  20. doi request reprint Abciximab and heparin versus bivalirudin for non-ST-elevation myocardial infarction
    Adnan Kastrati
    Deutsches Herzzentrum, Technische Universitat, Munich, Germany
    N Engl J Med 365:1980-9. 2011
    ..We compared the two treatments in this patient population...
  21. ncbi request reprint Effect of glycoprotein IIb/IIIa receptor blockade on recovery of coronary flow and left ventricular function after the placement of coronary-artery stents in acute myocardial infarction
    F J Neumann
    Deutsches Herzzentrum and 1 Medizinische Klinik der Technischen Universität München, Munich, Germany
    Circulation 98:2695-701. 1998
    ..We investigated the effect of abciximab with stent placement in acute myocardial infarction...
  22. doi request reprint Bivalirudin versus unfractionated heparin during percutaneous coronary intervention
    Adnan Kastrati
    Deutsches Herzzentrum, Technische Universitat, Munich, Germany
    N Engl J Med 359:688-96. 2008
    ..Whether bivalirudin is superior to unfractionated heparin in patients with stable or unstable angina who undergo percutaneous coronary intervention (PCI) after pretreatment with clopidogrel is unknown...
  23. ncbi request reprint Coronary and myocardial angiography: angiographic assessment of both epicardial and myocardial perfusion
    C Michael Gibson
    Thrombolysis in Myocardial Infarction TIMI Study Group, Harvard Medical School and Deutsches Herzzentrum, Munchen, Germany
    Circulation 109:3096-105. 2004
  24. ncbi request reprint Clinical evidence on polymer-based sirolimus and paclitaxel eluting stents
    R Iijima
    Deutsches Herzzentrum, Technische Universitat, Lazarettstrasse 36, 80636 Munich, Germany
    Minerva Cardioangiol 54:539-55. 2006
    ..Because polymers used for stent coating are often seen at the origin of the compromised long-term safety of DES, new technologies able to avoid permanent polymers may offer a valuable alternative...
  25. ncbi request reprint A randomized trial comparing stenting with balloon angioplasty in small vessels in patients with symptomatic coronary artery disease. ISAR-SMART Study Investigators. Intracoronary Stenting or Angioplasty for Restenosis Reduction in Small Arteries
    A Kastrati
    Deutsches Herzzentrum, Lazarettstr 36, 80636 M nchen, Germany
    Circulation 102:2593-8. 2000
    ..The objective of this randomized trial was to assess whether compared with PTCA, stenting of small coronary vessels is associated with a reduction of restenosis...
  26. doi request reprint Isolated and interactive impact of common CYP2C19 genetic variants on the antiplatelet effect of chronic clopidogrel therapy
    D Sibbing
    Deutsches Herzzentrum München and 1 Medizinische Klinik, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
    J Thromb Haemost 8:1685-93. 2010
    ..Currently, the isolated and interactive impacts of both variants on the antiplatelet effects of chronic clopidogrel therapy are unknown...
  27. ncbi request reprint Increased risk of restenosis after placement of gold-coated stents: results of a randomized trial comparing gold-coated with uncoated steel stents in patients with coronary artery disease
    A Kastrati
    Deutsches Herzzentrum and 1 Medizinische Klinik rechts der Isar der Technischen Universität, Munich, Germany
    Circulation 101:2478-83. 2000
    ..In this randomized trial, we assessed whether gold-coated stents were associated with a better clinical and angiographic outcome after coronary placement...
  28. ncbi request reprint Recovery of myocardial perfusion in acute myocardial infarction after successful balloon angioplasty and stent placement in the infarct-related coronary artery
    F J Neumann
    Deutsches Herzzentrum und 1 Medizinische Klinik and the Nuklearmedizinische Klinik der Technischen Universität München, Munich, Germany
    J Am Coll Cardiol 30:1270-6. 1997
    ..This study sought to investigate changes in myocardial perfusion after direct percutaneous transluminal coronary angioplasty (PTCA) in acute myocardial infarction (MI)...
  29. ncbi request reprint Bivalirudin reduces platelet and monocyte activation after elective percutaneous coronary intervention
    Gabriele Busch
    Deutsches Herzzentrum, Lazarettstrasse 36, 80636 Munich, Germany
    Thromb Haemost 101:340-4. 2009
    ..In conclusion, our data suggest that bivalirudin may reduce platelet and monocyte activation in patients undergoing elective PCI. Thereby, bivalirudin might reduce periinterventional thrombotic complications...
  30. doi request reprint No association of chromosome 9p21.3 variation with clinical and angiographic outcomes after placement of drug-eluting stents
    Petra Hoppmann
    Deutsches Herzzentrum München and 1 Medizinische Klinik, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
    JACC Cardiovasc Interv 2:1149-55. 2009
    ..3 is a genetic factor for coronary heart disease, we investigated whether this locus influenced the clinical and angiographic outcomes after implantation of drug-eluting stents in coronary arteries...
  31. ncbi request reprint Restenosis after coronary placement of various stent types
    A Kastrati
    Deutsches Herzzentrum and 1 Medizinische Klinik rechts der Isar, and Institut für Medizinische Statistik und Epidemiologie KU, Technische Universitat, Munich, Germany
    Am J Cardiol 87:34-9. 2001
    ..Among these factors, stent design appears to play a particularly important role in the hyperplastic response of the vessel wall...
  32. ncbi request reprint Glycoprotein Ia C807T polymorphism and risk of restenosis following coronary stenting
    N von Beckerath
    Deutsches Herzzentrum München and 1 Medizinische Klinik rechts der Isar, Technische Universitat Munchen, Lazarettstr 36, 80636, Munich, Germany
    Atherosclerosis 156:463-8. 2001
    ..6% for CC, 21.7% for CT and 21.2% for TT patients (P=0.98). Thus, carriage of the GP Ia T807 allele is not associated with an increased risk of restenosis or unfavorable late outcome following coronary artery stenting...
  33. ncbi request reprint Intraoperative recordings of monophasic action potentials with chronically implantable pacemaker leads
    B Zrenner
    Deutsches Herzzentrum Munchen, Technische Universitat Munchen, Germany
    Pacing Clin Electrophysiol 21:235-8. 1998
    ..Intraoperative recordings of MAP are possible with all implanted pacemaker leads. The recordings of typical MAP signals were always accompanied with stable electrode positions and good sensing and pacing characteristics...
  34. ncbi request reprint Clinical experience with a novel multielectrode basket catheter in right atrial tachycardias
    C Schmitt
    Deutsches Herzzentrum Munchen, Medizinische Klinik, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
    Circulation 99:2414-22. 1999
    ..The aim of our study was to evaluate possible advantages of a novel multielectrode basket catheter (MBC) in patients with AT...
  35. doi request reprint Pre-procedural C-reactive protein levels and clinical outcomes after percutaneous coronary interventions with and without abciximab: pooled analysis of four ISAR trials
    R Iijima
    Deutsches Herzzentrum, Technische Universitat, Munich, Germany
    Heart 95:107-12. 2009
    ....
  36. ncbi request reprint Prognostic value of the modified american college of Cardiology/American heart association stenosis morphology classification for long-term angiographic and clinical outcome after coronary stent placement
    A Kastrati
    Deutsches Herzzentrum and 1 Medizinische Klinik rechts der Isar, Technische Universitat Munchen, Munich, Germany
    Circulation 100:1285-90. 1999
    ..Lesion morphology is able to influence the restenosis process and thus the entire 1-year clinical course of these patients...
  37. ncbi request reprint Evaluation of prolonged antithrombotic pretreatment ("cooling-off" strategy) before intervention in patients with unstable coronary syndromes: a randomized controlled trial
    Franz Josef Neumann
    Medizinische Klinik, Technische Universitat Munchen, Munich, Germany
    JAMA 290:1593-9. 2003
    ..In unstable coronary syndromes, catheter intervention is frequently preceded by antithrombotic treatment to reduce periprocedural risk; however, evidence from clinical trials to support antithrombotic pretreatment is sparse...
  38. ncbi request reprint Predictive value of basal C-reactive protein levels for myocardial salvage in patients with acute myocardial infarction is dependent on the type of reperfusion treatment
    Alban Dibra
    Deutsches Herzzentrum, Technische Universitat Munchen, Munich, Germany
    Eur Heart J 24:1128-33. 2003
    ..To evaluate whether C-reactive protein (CRP) levels on admission are predictive of myocardial salvage achieved with different reperfusion strategies in patients with acute myocardial infarction (AMI)...
  39. ncbi request reprint Thrombolysis in myocardial infarction myocardial perfusion grade in angiography correlates with myocardial salvage in patients with acute myocardial infarction treated with stenting or thrombolysis
    Alban Dibra
    Deutsches Herzzentrum and 1 Medizinische Klinik rechts der Isar, Technische Universitat Munchen, Lazarettstrasse 36, 80 636 Munich, Germany
    J Am Coll Cardiol 41:925-9. 2003
    ..We sought to assess the relationship between the Thrombolysis In Myocardial Infarction (TIMI) myocardial perfusion (TMP) grade and myocardial salvage as well as the usefulness of TMP grade in comparing two different reperfusion strategies...
  40. ncbi request reprint Coronary artery stent placement with postprocedural antiplatelet therapy in acute myocardial infarction
    H Walter
    Deutsches Herzzentrum, Munchen, Germany
    Coron Artery Dis 9:577-82. 1998
    ..However, the concept of coronary stenting in AMI has not been validated in large cohorts. In this observational study, we investigated the outcome in 318 consecutive patients...
  41. ncbi request reprint Usefulness of intracoronary brachytherapy for in-stent restenosis with a 188Re liquid-filled balloon
    H Schuhlen
    Medizinische Klinik of the Klinikum rechts der Isar, Technische Universitat, Munich, Germany
    Am J Cardiol 87:463-6, A7. 2001
    ..A significant benefit from brachytherapy was seen at 6-month repeat angiography, as well as during the clinical follow-up of 12 months...
  42. doi request reprint Randomized trial of paclitaxel- versus sirolimus-eluting stents for treatment of coronary restenosis in sirolimus-eluting stents: the ISAR-DESIRE 2 (Intracoronary Stenting and Angiographic Results: Drug Eluting Stents for In-Stent Restenosis 2) study
    Julinda Mehilli
    Deutsches Herzzentrum, Technische Universitat, Munich, Germany
    J Am Coll Cardiol 55:2710-6. 2010
    ....
  43. ncbi request reprint Influence of lesion length on restenosis after coronary stent placement
    A Kastrati
    Deutsches Herzzentrum and 1 Medizinische Klinik rechts der Isar, Technische Universitat Munchen, Munich, Germany
    Am J Cardiol 83:1617-22. 1999
    ..The results of this study suggest that a possible way to reduce the risk is to cover the lesion with a minimal number of nonoverlapping stents...
  44. ncbi request reprint Previous cytomegalovirus infection and risk of coronary thrombotic events after stent placement
    F J Neumann
    Deutsches Herzzentrum, Technischen Universitat Munchen, Munich, Germany
    Circulation 101:11-3. 2000
    ..CMV infection may thereby increase the procoagulant properties of coronary artery plaques. This prospective study investigated the effect of previous CMV infection on the early hazard of coronary stent placement...
  45. ncbi request reprint Interlesion dependence of the risk for restenosis in patients with coronary stent placement in in multiple lesions
    A Kastrati
    Deutsches Herzzentrum and 1 Medizinische Klinik rechts der Isar, Technische Universitat Munchen, Munich, Germany
    Circulation 97:2396-401. 1998
    ..Our objective was to test the hypothesis that there is an intrapatient dependence of restenosis between lesions...
  46. ncbi request reprint Influence of stent design on 1-year outcome after coronary stent placement: a randomized comparison of five stent types in 1,147 unselected patients
    A Kastrati
    Deutsches Herzzentrum, Munchen, Germany
    Catheter Cardiovasc Interv 50:290-7. 2000
    ..01 +/- 0.70 mm to 1.20 +/- 0.82 mm (P = 0.085), and the incidence of restenosis varied between 25.3% and 35.9% (P = 0.145). Thus, stent design has a significant impact on the long-term results after coronary stent placement...
  47. ncbi request reprint Comparative characterization of cellular and molecular anti-restenotic profiles of paclitaxel and sirolimus. Implications for local drug delivery
    Rainer Wessely
    Deutsches Herzzentrum, Department of Cardiology 1 Medizinische Klinik rechts der Isar, University of Technology, Munich, Germany
    Thromb Haemost 97:1003-12. 2007
    ..In comparison with PTX, SRL shows minor interference with endothelial cell proliferation and migration, lower levels of cytotoxicity and apoptosis, a broader therapeutic range and distinctive immunosuppressive properties...
  48. doi request reprint Clopidogrel response status assessed with Multiplate point-of-care analysis and the incidence and timing of stent thrombosis over six months following coronary stenting
    Dirk Sibbing
    Deutsches Herzzentrum and 1 Medizinische Klinik rechts der Isar, Lazarettstrasse 36, 80636 München, Germany
    Thromb Haemost 103:151-9. 2010
    ..In the majority of clopidogrel low responders suffering ST, the ischaemic event occurs early in the course after the procedure...
  49. ncbi request reprint Methylenetetrahydrofolate reductase gene C677T and A1298C polymorphisms, plasma homocysteine, folate, and vitamin B12 levels and the extent of coronary artery disease
    Klaus Kölling
    Deutsches Herzzentrum and 1 Medizinische Klinik rechts der Isar der Technischen, Universität Munich, Lazarettstrasse 36, 80636 Munich, Germany
    Am J Cardiol 93:1201-6. 2004
    ..Although there is an apparent association between elevated levels of homocysteine and CAD, this association is not independent of conventional cardiovascular risk factors...
  50. ncbi request reprint Impact of diabetes mellitus on long-term outcomes in the drug-eluting stent era
    Raisuke Iijima
    Deutsches Herzzentrum, Technische Universtität, Munich, Germany
    Am Heart J 154:688-93. 2007
    ..Little is known about the late outcome of patients with diabetes mellitus who receive drug-eluting stents (DES)...
  51. doi request reprint Impact of bivalirudin or unfractionated heparin on platelet aggregation in patients pretreated with 600 mg clopidogrel undergoing elective percutaneous coronary intervention
    Dirk Sibbing
    Deutsches Herzzentrum and 1 Medizinische Klinik rechts der Isar, Technische Universitat Munchen, Munich, Germany
    Eur Heart J 29:1504-9. 2008
    ....
  52. ncbi request reprint Randomized clinical trial of abciximab in diabetic patients undergoing elective percutaneous coronary interventions after treatment with a high loading dose of clopidogrel
    Julinda Mehilli
    Deutsches Herzzentrum, Lazarettstrasse 36, 80636 Munich, Germany
    Circulation 110:3627-35. 2004
    ....
  53. ncbi request reprint Vessel size and outcome after coronary drug-eluting stent placement: results from a large cohort of patients treated with sirolimus- or paclitaxel-eluting stents
    Shpend Elezi
    Deutsches Herzzentrum, Technische Universitat, Munich, Germany
    J Am Coll Cardiol 48:1304-9. 2006
    ..This study sought to investigate the influence of vessel size on the outcomes of patients after drug-eluting stent (DES) implantation...
  54. ncbi request reprint Internal cardioversion of atrial fibrillation with a single lead configuration in a patient with massive diaphragmatic herniation
    M A Schneider
    Deutsches Herzzentrum, Klinikum rechts der Isar, Technische Universitat Munchen, Germany
    Pacing Clin Electrophysiol 21:2149-51. 1998
    ..An anatomically related circumstance is reported as indication for the internal low energy cardioversion instead of an external approach. A new single lead electrode configuration is described...
  55. ncbi request reprint Computer-assisted animation of atrial tachyarrhythmias recorded with a 64-electrode basket catheter
    B Zrenner
    Deutsches Herzzentrum München and Medizinische Klinik, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
    J Am Coll Cardiol 34:2051-60. 1999
    ..The aim of this study was to assess the value of a new mapping technique based on computer-assisted animation of multielectrode basket catheter (BC) recordings in patients with atrial arrhythmias...
  56. doi request reprint Distribution of angiographic measures of restenosis after drug-eluting stent implantation
    R A Byrne
    Deutsches Herzzentrum Munchen, Lazarettstrasse 36, 80636 Munich, Germany
    Heart 95:1572-8. 2009
    ..Drug-eluting stent (DES) treatment has attenuated the impact of certain factors (eg, diabetes) on restenosis but its effect on the distribution of indices of restenosis is not known...
  57. ncbi request reprint Impact of proton pump inhibitors on the antiplatelet effects of clopidogrel
    Dirk Sibbing
    Deutsches Herzzentrum and 1 Medizinische Klinik rechts der Isar, Technische Universitat Munchen, Munich, Germany
    Thromb Haemost 101:714-9. 2009
    ..Specifically designed and randomized clinical studies are needed to define the impact of concomitant PPI treatment on adverse events after percutaneous coronary intervention...
  58. doi request reprint Cytochrome 2C19*17 allelic variant, platelet aggregation, bleeding events, and stent thrombosis in clopidogrel-treated patients with coronary stent placement
    Dirk Sibbing
    Deutsches Herzzentrum Munchen, Lazarettstrasse 36, 80636 München, Germany
    Circulation 121:512-8. 2010
    ..The aim of this study was to assess the impact of CYP2C19*17 on ADP-induced platelet aggregation, the risk of bleeding, and stent thrombosis in clopidogrel-treated patients undergoing percutaneous coronary intervention...
  59. doi request reprint Protective effect of the CYP2C19 *17 polymorphism with increased activation of clopidogrel on cardiovascular events
    Klaus A Tiroch
    Deutsches Herzzentrum Munchen, Rechts der Isar, Technische Universitat, Germany
    Am Heart J 160:506-12. 2010
    ..Reduced-function alleles have been associated with an increase in cardiovascular events...
  60. ncbi request reprint Sex-based analysis of outcome in patients with acute myocardial infarction treated predominantly with percutaneous coronary intervention
    Julinda Mehilli
    Deutsches Herzzentrum, Lazarettstrasse 36, 80636 Munich, Germany
    JAMA 287:210-5. 2002
    ..It is not clear, however, whether sex is an independent predictor of death among patients systematically treated with aggressive reperfusion and medical strategies...
  61. ncbi request reprint Paclitaxel-eluting or sirolimus-eluting stents to prevent restenosis in diabetic patients
    Alban Dibra
    Deutsches Herzzentrum, Technische Universitat, Munich, Germany
    N Engl J Med 353:663-70. 2005
    ..It is not known whether there are differences in the effectiveness of currently approved drug-eluting stents in the high-risk subgroup of patients with diabetes mellitus...
  62. doi request reprint Aspirin and clopidogrel with or without phenprocoumon after drug eluting coronary stent placement in patients on chronic oral anticoagulation
    N Sarafoff
    Deutsches Herzzentrum Munchen, Klinik für Herz und Kreislauferkrankungen, Technische Universitat Munchen, Munich, Germany
    J Intern Med 264:472-80. 2008
    ..We investigated the efficacy and safety of two regimens of antithrombotic/anticoagulation therapy in patients who present for DES implantation whilst on OAC...
  63. ncbi request reprint A randomized trial comparing phosphorylcholine-coated stenting with balloon angioplasty as well as abciximab with placebo for restenosis reduction in small coronary arteries
    J Hausleiter
    Deutsches Herzzentrum Munchen, Klinik an der TU München, Munich, Germany
    J Intern Med 256:388-97. 2004
    ....
  64. ncbi request reprint Association of a CD18 gene polymorphism with a reduced risk of restenosis after coronary stenting
    W Koch
    Deutsches Herzzentrum Munchen, Munich, Germany
    Am J Cardiol 88:1120-4. 2001
    ..This finding suggests that Mac-1 is involved in the development of restenosis after coronary stent placement...
  65. ncbi request reprint Treatment of Chlamydia pneumoniae infection with roxithromycin and effect on neointima proliferation after coronary stent placement (ISAR-3): a randomised, double-blind, placebo-controlled trial
    F Neumann
    Medizinische Klinik, Technische Universitat Munchen, 81675, Munchen, Germany
    Lancet 357:2085-9. 2001
    ..Our aim was to investigate whether or not treatment of C pneumoniae infection with antibiotics prevents restenosis after coronary stent placement...
  66. ncbi request reprint Incidence of thrombotic occlusion and major adverse cardiac events between two and four weeks after coronary stent placement: analysis of 5,678 patients with a four-week ticlopidine regimen
    H Schuhlen
    Medizinische Klinik, Klinikum rechts der Isar, Munich, Germany
    J Am Coll Cardiol 37:2066-73. 2001
    ..We attempted to make a comprehensive assessment of the risk of stent failure (death, myocardial infarction or angiographically documented occlusion), differentiating early (first and second weeks) and late (third and fourth weeks) events...
  67. ncbi request reprint Interleukin-10 and tumor necrosis factor gene polymorphisms and risk of coronary artery disease and myocardial infarction
    W Koch
    Deutsches Herzzentrum München and 1 Medizinische Klinik rechts der Isar, Technische Universitat Munchen, Munich, Germany
    Atherosclerosis 159:137-44. 2001
    ....
  68. doi request reprint Risk of drug-eluting stent thrombosis in patients receiving proton pump inhibitors
    Nikolaus Sarafoff
    Deutsches Herzzentrum Munchen, Klinik für Herz und Kreislauferkrankungen Lazarettstr 3680636 Munich, Germany
    Thromb Haemost 104:626-32. 2010
    ..The higher mortality is probably due to confounding as patients on PPIs had a higher risk profile at baseline...
  69. ncbi request reprint Local cyclin-dependent kinase inhibition by flavopiridol inhibits coronary artery smooth muscle cell proliferation and migration: Implications for the applicability on drug-eluting stents to prevent neointima formation following vascular injury
    Birgit Jaschke
    Deutsches Herzzentrum and 1 Medizinische Klinik, Technische Universitat, Munich, Germany
    FASEB J 18:1285-7. 2004
    ..Therefore, this new class of therapeutics may be suitable for further clinical investigations on drug-eluting stents to prevent in-stent restenosis...
  70. ncbi request reprint Value of serum ferritin and soluble transferrin receptor for prediction of coronary artery disease and its clinical presentations
    Siegmund Braun
    Institut für Laboratoriumsmedizin, Deutsches Herzzentrum Munchen, Technische Universitat, Lazarettstrasse 36, 80636 München, Germany
    Atherosclerosis 174:105-10. 2004
    ..In subjects with pre-existing CAD, those with more severe disease had increased levels of sTfR. Patients with CAD presenting with acute coronary syndromes showed increased levels of serum ferritin...
  71. ncbi request reprint Prognostic value of myocardial salvage achieved by reperfusion therapy in patients with acute myocardial infarction
    Gjin Ndrepepa
    Deutsches Herzzentrum, Munich, Germany
    J Nucl Med 45:725-9. 2004
    ..The prognostic value of myocardial salvage index in patients with acute myocardial infarction after reperfusion therapy has not, however, been investigated...
  72. doi request reprint Erythropoietin-induced progenitor cell mobilisation in patients with acute ST-segment-elevation myocardial infarction and restenosis
    A Stein
    Ilka Ott, Deutsches Herzzentrum der Technischen Universität München, Lazarettstr 36, 80636 München, Germany
    Thromb Haemost 107:769-74. 2012
    ..EPO in patients with STEMI treated with PCI is associated with an increase in diameter stenosis that is not associated with circulating progenitor cells...
  73. doi request reprint P27 and P53 gene polymorphisms and restenosis following coronary implantation of drug-eluting stents
    K Tiroch
    Deutsches Herzzentrum Munchen, Munchen, Germany
    Cardiology 112:263-9. 2009
    ..We hypothesized that genetic variants of P27 and P53 influence the development of restenosis and the clinical outcome of patients receiving DES...
  74. ncbi request reprint Interferon-gamma and interferon-gamma receptor 1 and 2 gene polymorphisms and restenosis following coronary stenting
    K Tiroch
    Deutsches Herzzentrum München and 1 Medizinische Klinik rechts der Isar, Technische Universitat Munchen, Munchen, Germany
    Atherosclerosis 182:145-51. 2005
    ..61). Thus, this study does not support a clinically relevant role of the studied polymorphisms in the processes leading to in-stent restenosis...
  75. ncbi request reprint The recording of monophasic action potentials with fractal-coated iridium electrodes in humans
    B Zrenner
    Deutsches Herzzentrum Munchen, Germany
    Pacing Clin Electrophysiol 23:54-62. 2000
    ..92-0.99). The MAP sensing features of fractal-coated iridium and Ag/AgCl electrodes are comparable. The best results for recording of MAPs with fractal-coated electrodes can be achieved with small surface area tip electrodes...
  76. doi request reprint Long-term risk of adverse outcomes and new malignancies in patients treated with oral sirolimus for prevention of restenosis
    Sebastian Kufner
    Deutsches Herzzentrum, Technische Universitat, Munich, Germany
    JACC Cardiovasc Interv 2:1142-8. 2009
    ..We sought to investigate the long-term efficacy of oral sirolimus therapy and its impact on the incidence of de novo malignancies in the OSIRIS (Oral Sirolimus to Inhibit Recurrent In-Stent Stenosis) trial population...
  77. doi request reprint Profile of bleeding and ischaemic complications with bivalirudin and unfractionated heparin after percutaneous coronary intervention
    Raisuke Iijima
    Deutsches Herzzentrum, Technische Universitat, Lazarettstr 36, 80636 Munich, Germany
    Eur Heart J 30:290-6. 2009
    ....
  78. doi request reprint Impact of myocardial salvage assessed by (99m)Tc-sestamibi scintigraphy on cardiac autonomic function in patients undergoing mechanical reperfusion therapy for acute myocardial infarction
    Axel Bauer
    1 Medizinische Klinik und Deutsches Herzzentrum München, Munchen, Germany
    JACC Cardiovasc Imaging 2:449-57. 2009
    ..The purpose of this study was to analyze the impact of myocardial salvage on cardiac autonomic function in patients undergoing mechanical reperfusion therapy for acute myocardial infarction (MI)...
  79. ncbi request reprint Troponin level and efficacy of abciximab in patients with acute coronary syndromes undergoing early intervention after clopidogrel pretreatment
    Raisuke Iijima
    Deutsches Herzzentrum, Technische Universitat, Lazarettstr 36, 80636, Munich, Germany
    Clin Res Cardiol 97:160-8. 2008
    ....
  80. doi request reprint Impact of a reduced tube voltage on CT angiography and radiation dose: results of the PROTECTION I study
    Bernhard Bischoff
    Klinik für Herz und Kreislauferkrankungen, Deutsches Herzzentrum Munchen, Klinik an der TU München, Munich, Germany
    JACC Cardiovasc Imaging 2:940-6. 2009
    ....
  81. doi request reprint Periprocedural bleeding and 1-year outcome after percutaneous coronary interventions: appropriateness of including bleeding as a component of a quadruple end point
    Gjin Ndrepepa
    Deutsches Herzzentrum, Technische Universitat, Munich, Germany
    J Am Coll Cardiol 51:690-7. 2008
    ....
  82. ncbi request reprint Thoracic radiotherapy in patients with lymphoma and restenosis after coronary stent placement
    Kathrin Schömig
    Deutsches Herzzentrum, Technische Universität Munich, Munich, Germany
    Catheter Cardiovasc Interv 70:359-65. 2007
    ..The aim of this study was to assess the incidence of restenosis after coronary stenting in patients with lymphoma treated with thoracic radiation...
  83. ncbi request reprint Stem cell mobilization by granulocyte colony-stimulating factor in patients with acute myocardial infarction: a randomized controlled trial
    Dietlind Zohlnhofer
    Deutsches Herzzentrum, Technische Universitat Munchen, Munich, Germany
    JAMA 295:1003-10. 2006
    ..Granulocyte colony-stimulating factor (G-CSF) induces mobilization of bone marrow stem cells...
  84. ncbi request reprint Association between C-reactive protein levels and subsequent cardiac events among patients with stable angina treated with coronary artery stenting
    Alban Dibra
    Deutsches Herzzentrum and Medizinische Klinik rechts der Isar, Technische Universität Mnchen, Munich, Germany
    Am J Med 114:715-22. 2003
    ..To investigate the prognostic value of elevated C-reactive protein levels in patients with stable angina who underwent coronary stenting...
  85. ncbi request reprint Gender and restenosis after coronary artery stenting
    Julinda Mehilli
    Medizinische Klinik rechts der Isar der Technischen Universität, Munich, Germany
    Eur Heart J 24:1523-30. 2003
    ..To examine the impact of sex on restenosis in a large cohort of consecutive patients undergoing coronary stenting and systematic angiographic and clinical follow-up...
  86. doi request reprint Choice of contrast medium in patients with impaired renal function undergoing percutaneous coronary intervention
    Rainer Wessely
    Deutsches Herzzentrum and 1 Medizinische Klinik, Klinikum rechts der Isar, Technische Universitat, Munich, Germany
    Circ Cardiovasc Interv 2:430-7. 2009
    ..Therefore, the aim of this study was to compare the effect of contemporary contrast media on nephrotoxicity in this high-risk patient population...
  87. pmc Myocardial blood volume and the amount of viable myocardium early after mechanical reperfusion of acute myocardial infarction: prospective study using venous contrast echocardiography
    P Andrássy
    Deutsches Herzzentrum Munchen, Lazarettstrasse 36, D 80636 Munich, Germany
    Heart 87:350-5. 2002
    ....
  88. ncbi request reprint Electrophysiologic characteristics of paroxysmal and chronic atrial fibrillation in human right atrium
    B Zrenner
    Deutsches Herzzentrum München and 1 Medizinische Klinik, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
    J Am Coll Cardiol 38:1143-9. 2001
    ..The aim of the study was to analyze the electrophysiologic characteristics of paroxysmal (PAF) and chronic (CAF) atrial fibrillation (AF) in the human right atrium (RA)...
  89. ncbi request reprint Glycoprotein IIb/IIIa receptor blockade with coronary stent placement
    F J Neumann
    Deutsches Herzzentrum, Munchen, Germany
    Semin Interv Cardiol 3:81-90. 1998
    ..Another group are patients with acute myocardial infarction. Moreover, the exquisitely high risk of residual dissection after stenting suggests to always employ GP IIb/IIIa blockade in this instance...
  90. pmc Efficacy of a new balloon catheter for internal cardioversion of chronic atrial fibrillation without anaesthesia
    E Alt
    Department of Cardiology, Deutsches Herzzentrum Munchen, Klinik an der Technischen Universität, Germany
    Heart 79:128-32. 1998
    ..To compare a new internal cardioversion system incorporated into a balloon guided catheter with a conventional two electrode system in patients with atrial fibrillation (AF)...
  91. ncbi request reprint Regional in vivo and in vitro characterization of autonomic innervation in cardiomyopathic human heart
    M Ungerer
    Medizinische Klinik, Technische Universitat Munchen, Munich, Germany
    Circulation 97:174-80. 1998
    ..The goal of the present study was to correlate HED-PET images with biochemical analysis of tissue samples...
  92. ncbi request reprint Inhibition of neointima formation after experimental coronary artery stenting: a new biodegradable stent coating releasing hirudin and the prostacyclin analogue iloprost
    E Alt
    I Medizinische Klinik and Deutsches Herzzentrum, and the Department of Experimental Surgery, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
    Circulation 101:1453-8. 2000
    ..To minimize acute stent thrombosis and development of restenosis, stents coated with biodegradable and nonbiodegradable polymers have been proposed to serve as sustained-release drug carriers...
  93. ncbi request reprint Value of programmed ventricular stimulation for prophylactic internal cardioverter-defibrillator implantation in postinfarction patients preselected by noninvasive risk stratifiers
    C Schmitt
    Deutsches Herzzentrum München and 1 Medizinische Klinik, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
    J Am Coll Cardiol 37:1901-7. 2001
    ....
  94. ncbi request reprint Effect of human recombinant interleukin-6 and interleukin-8 on monocyte procoagulant activity
    F J Neumann
    Deutsches Herzzentrum Munchen, Technischen Universitat Munchen, Germany
    Arterioscler Thromb Vasc Biol 17:3399-405. 1997
    ..Flow cytometry demonstrated that IL-6 and IL-8 induced an increase in TF surface expression on monocytes. Thus, IL-6 and IL-8 induce monocyte PCA by increasing mRNA, protein content, and surface expression of TF...
  95. ncbi request reprint Heme oxygenase-1 gene promoter polymorphism and restenosis following coronary stenting
    Klaus Tiroch
    Deutsches Herzzentrum Munchen, 1 Medizinische Klinik rechts der Isar, Technische Universitat Munchen, Lazarettstrasse 36, München D 80636, Germany
    Eur Heart J 28:968-73. 2007
    ..We evaluated, whether an association existed between this polymorphism and the incidence of restenosis after coronary stenting...
  96. doi request reprint Cytochrome P450 2C19 loss-of-function polymorphism and stent thrombosis following percutaneous coronary intervention
    Dirk Sibbing
    Department of Cardiology, Deutsches Herzzentrum and 1 Medizinische Klinik rechts der Isar, Technische Universitat Munchen, Munich, Germany
    Eur Heart J 30:916-22. 2009
    ..The aim of this study was to assess the impact of the CYP2C19 681G>A loss-of-function polymorphism on ST following PCI performed after pre-treatment with clopidogrel...
  97. ncbi request reprint Plasminogen activator inhibitor-1 4G/5G polymorphism and efficacy of reperfusion therapy in acute myocardial infarction
    Dirk Sibbing
    Deutsches Herzzentrum and 1 Medizinische Klinik rechts der Isar, Technische Universitat Munchen, Munich, Germany
    Blood Coagul Fibrinolysis 16:511-5. 2005
    ..The PAI-1 4G/5G polymorphism has no impact on the amount of myocardial salvage achieved by reperfusion with stenting or thrombolysis in patients with AMI...
  98. doi request reprint Novel role of the CXC chemokine receptor 3 in inflammatory response to arterial injury: involvement of mTORC1
    Johannes B K Schwarz
    Deutsches Herzzentrum, 1 Medizinische Klinik, Technische Universitat Munchen, Munchen, Germany
    Circ Res 104:189-200. 2009
    ..These results strongly indicate that CXCR3-dependent activation of mTORC1 directly links stimulation of the Th1 immune system with the proliferative response of intimal cells in vascular remodeling...
  99. doi request reprint Serial contrast-enhanced cardiac magnetic resonance imaging demonstrates regression of hyperenhancement within the coronary artery wall in patients after acute myocardial infarction
    Tareq Ibrahim
    Deutsches Herzzentrum München and 1 Medizinische Klinik des Klinikums Rechts der Isar, Technische Universitat Munchen, Munchen, Germany
    JACC Cardiovasc Imaging 2:580-8. 2009
    ..Our aim was to determine whether serial contrast-enhanced cardiac magnetic resonance (CE-CMR) is useful for the characterization of tissue signal changes within the coronary vessel wall in patients after acute myocardial infarction (AMI)...
  100. ncbi request reprint EMAP-II downregulation contributes to the beneficial effects of rapamycin after vascular injury
    Thomas G Nührenberg
    Klinik für Herz und Kreislaufkrankheiten, I Medizinische Klinik und Deutsches Herzzentrum der Technischen Universität München, Lazarettstr 36, D 80636 München, Germany
    Cardiovasc Res 77:580-9. 2008
    ..Here we investigated the interplay between EMAP-II and rapamycin after vascular injury in vivo...
  101. doi request reprint A polymer-free dual drug-eluting stent in patients with coronary artery disease: a randomized trial vs. polymer-based drug-eluting stents
    Robert A Byrne
    ISAR Centre, Deutsches Herzzentrum, Technische Universitat, Lazarettstrasse 36, 80636 Munich, Germany
    Eur Heart J 30:923-31. 2009
    ....