E V Potapov

..A minimally invasive approach for pump exchange on cardiopulmonary bypass for pump thrombosis and off-pump for cable damage or pump explantation is recommended...

..However, since the most recent changes in the design of the connection and modifications made in the implantation technique, no instance of cable damage has been registered...

..However, the effect of long-term CF with lack of peripheral arterial wall motions on blood pressure regulation and end-organ arterial wall sclerosis, especially in the case of long-term support (> 3 years), remains unclear...

..Women were underrepresented in the age group 13-50 years, and 50 years and older, and women had a higher risk for mortality on VAD support in the adult age groups (groups 2 and 3)...

..The present study demonstrates a relationship between the PlA genotype and postoperative complications in patients implanted with pulsatile and axial flow VADs...

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..This approach avoids the risks associated with repeat sternotomy and use of cardiopulmonary bypass and decreases the total costs of patient care...

..The current study investigates the relationship between these two markers and their prognostic value when one or both of them are elevated...

..However, the exact relationship between BMI and postoperative risk has not yet been defined...

..We report on the successful use of recombinant activated factor VII for control of massive bleeding after implantation of a biventricular assist device in a patient with prolonged severe cardiogenic shock...

..We report the first successful transcontinental air transport (from Singapore to Berlin, Germany) of a patient with fulminating myocarditis requiring implantation of a biventricular assist device...

..e. heart transplantation, implantation of a ventricular assist device or conservative treatment, is a key issue for therapeutic success...

..This unique experience shows that left ventricular assist device support can be extended beyond 4 years with good quality of life and low risk, making it a good alternative for non-transplant candidates...

..Causes of this rare but potentially lethal complication are discussed, as well as its prediction, diagnosis, and prevention...

..Additionally, new developments in the field of pediatric assist devices will be presented...

..The use of ventricular assist devices (VADs) in patients with chronic end-stage or acute heart failure has led to improved survival. We present our experience since 1987...

..Acidosis and high MODS score predict unfavorable outcome. However, the prediction of clinical outcome in patients in severe cardiogenic shock supported by BVAD is possible in extreme situations only...

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..Elevated cardiac troponins predict early graft failure after heart transplantation. This study evaluated the effects of acute brain death (BD) on the release of ANP, BNP, big ET-1, and cardiac troponins in an animal model...

..The distal stenosis of the RCA was treated successfully with dilation and stent implantation. The patient is presently in stable condition on LVAD and awaits transplantation as an outpatient...

..Cardiac troponin I and T (cTnI and cTnT) are sensitive and specific markers of myocardial damage. We evaluated them for the selection of heart donors and as predictors of early graft failure after heart transplantation...

..To detect the flow in peripheral vessels, we measured transcranial Doppler signals in patients after implantation...

..Right ventricular (RV) dysfunction develops in 20% to 50% of patients after LVAD implantation, leading to prolonged ICU stay and elevated mortality. However, the prediction of RV failure remains difficult...

..Surgery was undertaken: first, the initial resection and drainage of the thoracic portion of the pseudocyst, and second, a thorough cleansing of the entire cyst through median laparotomy 15 days later...

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..Central shunt (CS) is frequently used to treat diminished pulmonary blood flow in newborns. We analyzed the impact of CS on the growth of the pulmonary arteries (PAs)...

..The number of older patients undergoing operations with cardiopulmonary bypass (CPB) is increasing. The aim of the present study was to evaluate the impact of cardiac surgery using CPB on the long-term course of CLL...

..We evaluated PCT as a predictor of early graft failure-related mortality after HTx...

..In patients with low-output syndrome despite IABP support, implantation of a ventricular assist system should be considered...

..Since 1994 the blood-contacting surfaces of the device system have been heparin-coated. In this report the experiences with VAD support in 28 children are presented...

..Day-by-day surveillance of the heart and prompt treatment of any rejection may yield improved long-term survival...

..In one patient with preoperatively noted MES the prevalence of MES postoperatively was 50%. The high speed rotating impeller of the DeBakey VAD did not produce any detectable microthrombi or bubbles from cavitation effects...

..We analyzed the occurrence of HPF4/A and thromboembolism in patients with heparin-coated and noncoated VADs...

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..Further investigations are necessary for evaluation of the pathophysiologic mechanism and clinical implications of these findings...

..Donor heart shortage has necessitated the expansion of the donor pool by the use of older hearts...

..The objective was to validate renal flow measurements with Doppler guidewires and to apply this technique to assess dose and time dependency of the renal vascular effects of norepinephrine (NE)...

..Our newly developed bioreactor provides optimal biomechanical and biodynamical stimuli for controlled tissue development and in vitro conditioning of an autologous tissue-engineered patch...

..His work represents a milestone in the history of heart surgery...

..Many patients with congestive heart failure develop cardiac cachexia. In this study the association between BMI and outcomes after VAD implantation was investigated...

..We report an unusual case of a pseudocyst in the left ventricular outflow tract in a 58-year-old woman. The cyst was successfully resected by a transatrial approach...

..Nevertheless, indications for and timing of the implantation of a VAD in patients who have received an intra-aortic balloon pump (IABP) remain unclear...

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..The present report summarizes the clinical experience with patients treated for severe cardiogenic shock for the first time with a newly developed axial flow pump with magnetically levitated bearings...

..With advanced reliability of artificial blood pumps and in face of the high incidence of heart failure, especially in the older age group, the long-term application of artificial bloods pump appears to be justified...

..Our newly developed combination of a cell seeding and conditioning device provides sterile conditions and biodynamic stimuli for controlled tissue development and in vitro conditioning of an autologous tissue-engineered vessel...

..This approach avoids reopening the chest through a median sternotomy and reduces the risk of bleeding and subsequent complications...

..Our preliminary results suggest that the reproduction of complex anatomic structures by rapid prototyping techniques may be useful to fabricate custom made polymeric scaffolds for the tissue engineering of heart valves...

..In the long-term, multicenter use of the Assist Database could be considered...