Research Topics
| Jorg HausleiterSummaryAffiliation: Deutsches Herzzentrum Country: Germany Publications
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Detail Information
Publications
A randomized trial comparing phosphorylcholine-coated stenting with balloon angioplasty as well as abciximab with placebo for restenosis reduction in small coronary arteriesJ Hausleiter
Deutsches Herzzentrum Munchen, Klinik an der TU München, Munich, Germany
J Intern Med 256:388-97. 2004....
Image quality and radiation exposure with prospectively ECG-triggered axial scanning for coronary CT angiography: the multicenter, multivendor, randomized PROTECTION-III studyJorg Hausleiter
Klinik für Herz und Kreislauferkrankungen, Deutsches Herzzentrum Munchen, Klinik an der Technischen Universität München, Munich, Germany
JACC Cardiovasc Imaging 5:484-93. 2012....
Validation of the localization of the target tissue for intracoronary brachytherapyJorg Hausleiter
Deutsches Herzzentrum München Lazarettstrasse 36 80636 München, Germany
Z Kardiol 91:10-6. 2002..6 to 0.7 mm as well as the relationship between dose and ICBT effectiveness at this depth. The data provide a rationale for setting a common dose prescription point at 0.6 to 0.7 mm tissue depth...
Image quality and radiation exposure with a low tube voltage protocol for coronary CT angiography results of the PROTECTION II TrialJorg Hausleiter
Klinik für Herz und Kreislauferkrankungen, Deutsches Herzzentrum Munchen, Klinik an der Technischen Universität München, Munich, Germany
JACC Cardiovasc Imaging 3:1113-23. 2010..The purpose of this study was to evaluate image quality and radiation dose using a 100 kVp tube voltage scan protocol compared with standard 120 kVp for coronary computed tomography angiography (CTA)...
Radiation dose estimates from cardiac multislice computed tomography in daily practice: impact of different scanning protocols on effective dose estimatesJorg Hausleiter
Klinik für Herz und Kreislauferkrankungen, Deutsches Herzzentrum Munchen, Klinik an der TU München, Munich, Germany
Circulation 113:1305-10. 2006..The objective of this retrospective investigation was to compare the estimated dose received during 16- and 64-slice CTA in daily practice and to investigate the impact of different scan protocols on dose and image quality...
Randomized, double-blind, placebo-controlled trial of oral sirolimus for restenosis prevention in patients with in-stent restenosis: the Oral Sirolimus to Inhibit Recurrent In-stent Stenosis (OSIRIS) trialJorg Hausleiter
Deutsches Herzzentrum Munchen, Klinik an der TU München, Munchen, Germany
Circulation 110:790-5. 2004....
Prevalence of noncalcified coronary plaques by 64-slice computed tomography in patients with an intermediate risk for significant coronary artery diseaseJorg Hausleiter
Klinik für Herz und Kreislauferkrankungen, Klinik an der TU München, Munich, Germany
J Am Coll Cardiol 48:312-8. 2006....
Feasibility of dual-source cardiac CT angiography with high-pitch scan protocolsJorg Hausleiter
Klinik für Herz und Kreislauferkrankungen, Deutsches Herzzentrum München Klinik an der TU München, Lazarettstrasse 36, 80636 Munich, Germany
J Cardiovasc Comput Tomogr 3:236-42. 2009....
Impact of lesion complexity on the capacity of a trial to detect differences in stent performance: results from the ISAR-STEREO trialJorg Hausleiter
Deutsches Herzzentrum and Medizinische Klinik des Klinikums rechts der Isar, Technische Universitat, Munich, Germany
Am Heart J 146:882-6. 2003..The rationale of this study was to investigate the role of lesion complexity on the capacity of a stent-versus-stent trial to distinguish between superior and inferior stents...
Non-invasive coronary computed tomographic angiography for patients with suspected coronary artery disease: the Coronary Angiography by Computed Tomography with the Use of a Submillimeter resolution (CACTUS) trialJorg Hausleiter
Deutsches Herzzentrum Munchen, Klinik für Herz und Kreislauferkrankungen, Klinik an der TU München, Munich, Germany
Eur Heart J 28:3034-41. 2007....
Estimated radiation dose associated with cardiac CT angiographyJorg Hausleiter
Department of Cardiology, Deutsches Herzzentrum Munchen, Klinik an der Technischen Universität München, Lazarettstrasse 36, 80636 München, Germany
JAMA 301:500-7. 2009..However, the potential risks due to exposure to ionizing radiation associated with CCTA have raised concerns...
Impact of acute myocardial infarct location on myocardial salvage after stenting or thrombolysis (results from the STOPAMI 1 and 2 trials): Stent versus Thrombolysis for Occluded coronary arteries in Patients with Acute Myocardial InfarctionJorg Hausleiter
Deutsches Herzzentrum and 1 Medizinische Klinik des Klinikums rechts der Isar, Technische Universitat, Munich, Germany
Am J Cardiol 91:341-3. 2003
A porcine coronary stent model of increased neointima formation in the left anterior descending coronary arteryJ Hausleiter
Deutsches Herzzentrum München Lazarettstrasse 36 80636 München, Germany
Z Kardiol 91:614-9. 2002..This study investigates whether the coronary artery affects the relationship between arterial injury and neointima hyperplasia in the porcine stent model...
Predictive factors for early cardiac events and angiographic restenosis after coronary stent placement in small coronary arteriesJorg Hausleiter
Deutsches Herzzentrum Munchen, Munich, Germany
J Am Coll Cardiol 40:882-9. 2002..The rationale of this study was to identify risk factors that predict early thrombotic events and angiographic restenosis after stenting in small coronary arteries...
Comparative analysis of stent placement versus balloon angioplasty in small coronary arteries with long narrowings (the Intracoronary Stenting or Angioplasty for Restenosis Reduction in Small Arteries [ISAR-SMART] Trial)Jorg Hausleiter
German Heart Center, Munich, Germany
Am J Cardiol 89:58-60. 2002
Tips to minimize radiation exposureJorg Hausleiter
Deutsches Herzzentrum Munchen, Klinik an der Technischen Universität München, Munich, Germany
J Cardiovasc Comput Tomogr 2:325-7. 2008..Therefore, these strategies should be rigidly applied in daily practice to obtain diagnostic images with the lowest possible radiation dose in every patient...
Prevention of restenosis by a novel drug-eluting stent system with a dose-adjustable, polymer-free, on-site stent coatingJorg Hausleiter
Deutsches Herzzentrum Munchen, Klinik an der Technischen Universität München, Lazarettstrasse 36, 80636 Munich, Germany
Eur Heart J 26:1475-81. 2005..The objective of this prospective dose finding study was to assess the feasibility, safety, and efficacy of a polymer-free on-site stent coating with increasing rapamycin doses...
Prognostic value of coronary computed tomographic angiography in patients with arterial hypertensionMartin Hadamitzky
Klinik für Herz und Kreislauferkrankungen, Deutsches Herzzentrum Munchen, Technische Universitat Munchen, Lazarettstrasse 36, 80636 München, Germany
Int J Cardiovasc Imaging 28:641-50. 2012..3% for patients without obstructive CAD and 1.5% for patients with obstructive CAD. In hypertensive patients without known CAD, coronary CT angiography allows for the identification of patients at high risk for incident cardiac events...
A randomized, double-blind, placebo-controlled trial on restenosis prevention by the receptor tyrosine kinase inhibitor imatinibDietlind Zohlnhofer
Deutsches Herzzentrum Munchen, Munich, Germany
J Am Coll Cardiol 46:1999-2003. 2005....
Comparison of sequential and helical scanning for radiation dose and image quality: results of the Prospective Multicenter Study on Radiation Dose Estimates of Cardiac CT Angiography (PROTECTION) I StudyBernhard Bischoff
Klinik für Herz und Kreislauferkrankungen, Deutsches Herzzentrum Munchen, Munich, Bavaria 80636, Germany
AJR Am J Roentgenol 194:1495-9. 2010....
Paclitaxel-eluting balloons, paclitaxel-eluting stents, and balloon angioplasty in patients with restenosis after implantation of a drug-eluting stent (ISAR-DESIRE 3): a randomised, open-label trialRobert A Byrne
Deutsches Herzzentrum, Technische Universitat, Munich, Germany
Lancet 381:461-7. 2013..We investigated the efficacy of paclitaxel-eluting balloons (PEB), paclitaxel-eluting stents (PES), and balloon angioplasty in these patients...
Impact of a reduced tube voltage on CT angiography and radiation dose: results of the PROTECTION I studyBernhard Bischoff
Klinik für Herz und Kreislauferkrankungen, Deutsches Herzzentrum Munchen, Klinik an der TU München, Munich, Germany
JACC Cardiovasc Imaging 2:940-6. 2009....
Intracoronary stenting and angiographic results: strut thickness effect on restenosis outcome (ISAR-STEREO-2) trialJürgen Pache
Deutsches Herzzentrum, Munich, Germany
J Am Coll Cardiol 41:1283-8. 2003..We tested the hypothesis that thinner-strut stents are associated with a reduced rate of restenosis when comparing two stents with different design...
Abciximab and angiographic restenosis after coronary stent placement. Analysis of the angiographic substudy of ISAR-REACT--a double-blind, placebo-controlled, randomized trial evaluating abciximab in patients undergoing elective percutaneous coronary inteHelmut Schühlen
Deutsches Herzzentrum, Munich, Germany
Am Heart J 151:1248-54. 2006..Previous analyses have suggested a reduction in the incidence of restenosis after the administration of abciximab...
Drug-eluting versus bare-metal stents in saphenous vein graft lesions (ISAR-CABG): a randomised controlled superiority trialJulinda Mehilli
Deutsches Herzzentrum, Technische Universitat, Munich, Germany
Lancet 378:1071-8. 2011..We aimed to undertake a comparison in a randomised trial powered for clinical endpoints...
Prognostic value of coronary computed tomographic angiography in comparison with calcium scoring and clinical risk scoresMartin Hadamitzky
Klinik für Herz und Kreislauferkrankungen, Deutsches Herzzentrum Munchen, Hospital at the Technische Universität München, Munich, Germany
Circ Cardiovasc Imaging 4:16-23. 2011..Therefore, we compared CCTA with calcium scoring and clinical risk scores for the ability to predict cardiac events...
Biodegradable polymer versus permanent polymer drug-eluting stents and everolimus- versus sirolimus-eluting stents in patients with coronary artery disease: 3-year outcomes from a randomized clinical trialRobert A Byrne
Deutsches Herzzentrum, Technische Universitat, Munich, Germany
J Am Coll Cardiol 58:1325-31. 2011..The aim of this study was to compare the 3-year efficacy and safety of biodegradable polymer with permanent polymer stents and of everolimus-eluting stents (EES) with sirolimus-eluting stents (SES)...
Polymer-free sirolimus- and probucol-eluting versus new generation zotarolimus-eluting stents in coronary artery disease: the Intracoronary Stenting and Angiographic Results: Test Efficacy of Sirolimus- and Probucol-Eluting versus Zotarolimus-eluting StenSteffen Massberg
Deutsches Herzzentrum, Technische Universitat, Munich, Germany
Circulation 124:624-32. 2011..A polymer-free dual-drug sirolimus- and probucol-eluting stent and a new generation permanent polymer zotarolimus-eluting stent are recently developed technologies demonstrating encouraging results...
Long-term risk of adverse outcomes and new malignancies in patients treated with oral sirolimus for prevention of restenosisSebastian Kufner
Deutsches Herzzentrum, Technische Universitat, Munich, Germany
JACC Cardiovasc Interv 2:1142-8. 2009..We sought to investigate the long-term efficacy of oral sirolimus therapy and its impact on the incidence of de novo malignancies in the OSIRIS (Oral Sirolimus to Inhibit Recurrent In-Stent Stenosis) trial population...
Inhibition of neointima formation by a novel drug-eluting stent system that allows for dose-adjustable, multiple, and on-site stent coatingRainer Wessely
Deutsches Herzzentrum and 1 Medizinische Klinik, Technische Universitat, Lazarettstr 36, 80636 München, Germany
Arterioscler Thromb Vasc Biol 25:748-53. 2005..The risk of in-stent restenosis can be considerably reduced by stents eluting cytostatic compounds. We created a novel drug-eluting stent system that includes several new features in the rapidly evolving field of stent-based drug delivery...
Sirolimus-eluting stent or paclitaxel-eluting stent vs balloon angioplasty for prevention of recurrences in patients with coronary in-stent restenosis: a randomized controlled trialAdnan Kastrati
Deutsches Herzzentrum, Technische Universitat, Munich, Germany
JAMA 293:165-71. 2005..It is less clear whether drug-eluting stents are superior to conventional balloon angioplasty for the treatment of patients with in-stent restenosis...
Improved noninvasive assessment of coronary artery bypass grafts with 64-slice computed tomographic angiography in an unselected patient populationTanja S Meyer
Institut für Radiologie und Nuklearmedizin, Deutsches Herzzentrum Munchen, Klinik an der TU München, Munich, Germany
J Am Coll Cardiol 49:946-50. 2007....
Prognostic value of coronary computed tomographic angiography for prediction of cardiac events in patients with suspected coronary artery diseaseMartin Hadamitzky
Klinik für Herz und Kreislauferkrankungen, Deutsches Herzzentrum Munchen, Technische Universitat Munchen, Munich, Germany
JACC Cardiovasc Imaging 2:404-11. 2009..We assessed the rate of cardiac events after detection or exclusion of obstructive coronary artery disease (CAD) by coronary computed tomography angiography (CCTA)...
Abciximab and heparin versus bivalirudin for non-ST-elevation myocardial infarctionAdnan Kastrati
Deutsches Herzzentrum, Technische Universitat, Munich, Germany
N Engl J Med 365:1980-9. 2011..We compared the two treatments in this patient population...
Cardiovascular risk assessment based on the quantification of coronary calcium in contrast-enhanced coronary computed tomography angiographyBernhard Bischoff
Klinik für Herz und Kreislauferkrankungen, Deutsches Herzzentrum Munchen, Klinik an der TU München, Lazarettstrasse 36, Munich, Germany
Eur Heart J Cardiovasc Imaging 13:468-75. 2012..The aim of this analysis was to develop and validate a method for CAC risk classification in CCTA...
Restenosis detected by routine angiographic follow-up and late mortality after coronary stent placementHelmut Schühlen
Deutsches Herzzentrum Munchen, Technische Universitat, Munich, Germany
Am Heart J 147:317-22. 2004..The purpose of this study was to assess the impact of angiographic restenosis detected by FU angio on late mortality after coronary stent placement...
Trends in radiation protection in CT: present and future statusBernhard Bischoff
Klinik für Herz und Kreislauferkrankungen, Deutsches Herzzentrum Munchen, Lazarettstrasse 36, 80636 Munich, Germany
J Cardiovasc Comput Tomogr 3:S65-73. 2009..Because the contrast-enhanced CT angiography is the largest part of the total study dose, the following described strategies focus on radiation dose reduction for CCTA image acquisition...
Reduction of radiation dose estimates in cardiac 64-slice CT angiography in patients after coronary artery bypass graft surgeryFranziska Hermann
Institut für Radiologie und Nuklearmedizin, Deutsches Herzzentrum Munchen, Munchen, Munchen, Germany
Invest Radiol 43:253-60. 2008....
Prognostic value of sensitive troponin T in patients with stable and unstable angina and undetectable conventional troponinGjin Ndrepepa
Deutsches Herzzentrum, Technische Universitat, Munich, Germany
Am Heart J 161:68-75. 2011..The objective of this study was to investigate the prognostic value of sensitive cardiac troponin in patients with stable and unstable angina presenting with undetectable levels of conventional troponin...
Prognostic value of coronary computed tomographic angiography in asymptomatic patientsMartin Hadamitzky
Deutsches Herzzentrum Munchen, Hospital at the Technische Universität München, Munich, Germany
Am J Cardiol 105:1746-51. 2010..In conclusion, although the event rate was low in asymptomatic patients, CCTA could reliably predict further cardiac events and could reclassify 2/3 of patients regarding their cardiovascular risk...
Prognostic value of coronary computed tomographic angiography in diabetic patients without known coronary artery diseaseMartin Hadamitzky
Klinik für Herz und Kreislauferkrankungen, Deutsches Herzzentrum Munchen, Hospital at the Technische Universität München, Munich, Germany
Diabetes Care 33:1358-63. 2010..We assessed the ability of coronary computed tomography angiography (CCTA) to detect CAD in diabetic patients and to predict subsequent cardiac events...
Dual thienopyridine low-response to clopidogrel and prasugrel in a patient with STEMI, cardiogenic shock and early stent thrombosis is overcome by ticagrelorMartin Orban
Deutsches Herzzentrum München and 1 Medizinische Klinik, Technische Universitat Munchen, Munich, Germany
Platelets 23:395-8. 2012....
The pre-clinical assessment of rapamycin-eluting, durable polymer-free stent coating conceptsKristin Steigerwald
Deutsches Herzzentrum, Klinikum rechts der Isar, Technische Universitat, Munich, Germany
Biomaterials 30:632-7. 2009..These results encourage the transfer of these technologies to clinical evaluation...
Morphological assessment of renal arteries after radiofrequency catheter-based sympathetic denervation in a porcine modelKristin Steigerwald
Deutsches Herzzentrum München und I Med Klinik der Technischen Universität München, Munich, Germany
J Hypertens 30:2230-9. 2012..However, the local morphological changes within the vessel wall accompanying this technique remain elusive and we sought to characterize these by utilizing the simplicity radiofrequency catheter approach...
Association of midregional proadrenomedullin with coronary artery stenoses, soft atherosclerotic plaques and coronary artery calciumMarcel Roos
Abteilung für Nephrologie, Klinikum rechts der Isar, Ismaninger Str 22, 81675 Munich, Germany
Heart Vessels 27:352-9. 2012..Patients with decreased MR-proADM levels may need invasive examinations to diagnose more severe forms of coronary artery disease...
Prognostic value of impaired fasting glucose for outcomes of patients with stable angina pectoris treated with percutaneous coronary interventionsAlban Dibra
Deutsches Herzzentrum, Munich, Germany
Am J Cardiol 96:1113-5. 2005..29 to 4.08, p = 0.005). An IFG of 100 to 109 mg/dl in patients with stable angina who undergo percutaneous coronary intervention may identify a patient subset with an increased risk of death or myocardial infarction...
Sex-related effectiveness of bivalirudin versus abciximab and heparin in non-ST-segment elevation myocardial infarctionJulinda Mehilli
Klinikum der Universitaet Munich, Munich, Germany
Am Heart J 165:537-43. 2013..Bivalirudin is safer than abciximab plus heparin in patients with non-ST-segment elevation myocardial infarction (NSTEMI). Thus, a greater benefit of bivalirudin in women would be expected...
Gender differences in contrast-enhanced magnetic resonance imaging after acute myocardial infarctionBirgit Langhans
Institute for Clinical Radiology, Ludwig Maximilians University Hospital Munich, Ziemssenstraße 1, 80336 Munich, Germany
Int J Cardiovasc Imaging 29:643-50. 2013..Size of MVO, however, was significantly smaller in women and might reflect better cardioprotective mechanisms in women. Whether these changes have prognostic implications has to be tested on a larger patient population...
The assessment of area at risk and myocardial salvage after coronary revascularization in acute myocardial infarction: comparison between CMR and SPECTMartin Hadamitzky
Klinik für Herz und Kreislauferkrankungen, Deutsches Herzzentrum Munchen, Technische Universitat Munchen, Munich, Germany
JACC Cardiovasc Imaging 6:358-69. 2013..This study sought to compare cardiac magnetic resonance (CMR) and single-photon emission computed tomography (SPECT) for assessment of area at risk, scar size, and salvage area after coronary reperfusion in acute myocardial infarction...
[Paracardiac infiltrate or Turkish sword?]M Riedel
Klinik für Herz und Kreislauferkrankungen, Deutsches Herzzentrum, Technische Universitat Munchen
Pneumologie 57:78-82. 2003..The anomaly can remain asymptomatic until adult life...
Bivalirudin versus unfractionated heparin during percutaneous coronary interventionAdnan Kastrati
Deutsches Herzzentrum, Technische Universitat, Munich, Germany
N Engl J Med 359:688-96. 2008..Whether bivalirudin is superior to unfractionated heparin in patients with stable or unstable angina who undergo percutaneous coronary intervention (PCI) after pretreatment with clopidogrel is unknown...
Recovery of myocardial perfusion in acute myocardial infarction after successful balloon angioplasty and stent placement in the infarct-related coronary arteryF J Neumann
Deutsches Herzzentrum und 1 Medizinische Klinik and the Nuklearmedizinische Klinik der Technischen Universität München, Munich, Germany
J Am Coll Cardiol 30:1270-6. 1997..This study sought to investigate changes in myocardial perfusion after direct percutaneous transluminal coronary angioplasty (PTCA) in acute myocardial infarction (MI)...
Relation between plasma fibroblast growth factor-23, serum fetuin-A levels and coronary artery calcification evaluated by multislice computed tomography in patients with normal kidney functionMarcel Roos
Abteilung für Nephrologie, Klinikum rechts der Isar, Munich, Germany
Clin Endocrinol (Oxf) 68:660-5. 2008..To examine the correlation of plasma fibroblast growth factor (FGF)-23 and serum fetuin A levels with the coronary artery calcification score (CACS) in patients with normal kidney function...
Scimitar syndromeM Riedelp
Department of Cardiology, German Heart Centre, Technical University Munich, D-80636 Munich, Germany
Lancet 363:356. 2004
Usefulness of intracoronary brachytherapy for in-stent restenosis with a 188Re liquid-filled balloonH Schuhlen
Medizinische Klinik of the Klinikum rechts der Isar, Technische Universitat, Munich, Germany
Am J Cardiol 87:463-6, A7. 2001..A significant benefit from brachytherapy was seen at 6-month repeat angiography, as well as during the clinical follow-up of 12 months...
Acute beneficial hemodynamic effects of a novel 3D-echocardiographic optimization protocol in cardiac resynchronization therapyCarolin Sonne
Klinik für Herz und Kreislauferkrankungen des Erwachsenen, Deutsches Herzzentrum Munchen, Technische Universitat Munchen, Faculty of Medicine, Munich, Germany carolinsonne gmx de
PLoS ONE 7:e30964. 2012....
Dislocation of a stent-graft into the aortic arch during endovascular repair of a descending thoracic aortic aneurysmNorbert Augustin
Department of Cardiovascular Surgery, German Heart Center Munich, Clinic at the Technical University, Munich, Germany
Ann Thorac Surg 81:1502-5. 2006..Computed tomographic scan exhibited a complete covering of the supra-aortic vessels, and conventional, open aortic arch surgery was inevitable. A partial resection of the proximal part of the stent-graft was performed...
Mapping and ablation of atypical flutter in congenital heart disease with a novel three-dimensional mapping system (Carto Merge)Andreas Pflaumer
Department of Paediatric Cardiology and Congenital Heart Disease, Deutsches Herzzentrum Munchen, Klinik an der Technischen Universität München, Germany
Europace 8:138-9. 2006..In this case, the new system enabled us to display the complex anatomy of the right atrium in detail, whereas the conventional electro-anatomic three-dimensional geometry showed significant inconsistencies...
Is there an evidence of pulmonary vein stenosis following epicardial microwave ablation of atrial fibrillation?Christian Von Bary
Klinik für Herz und Kreislauferkrankungen, Deutsches Herzzentrum Munchen, Lazarettstrasse 36, 80636, Munich, Germany
J Interv Card Electrophysiol 25:193-7. 2009..However, little is known about potential procedure-related complications. We investigate, whether there is evidence of pulmonary vein stenosis (PVST) in patients with atrial fibrillation undergoing epicardial microwave ablation...
