Steffen Desch

Summary

Country: Germany

Publications

  1. ncbi Low vs. higher-dose dark chocolate and blood pressure in cardiovascular high-risk patients
    Steffen Desch
    Department of Cardiology, University of Leipzig Heart Center, Leipzig, Germany
    Am J Hypertens 23:694-700. 2010
  2. ncbi Bypass surgery versus percutaneous coronary intervention for the treatment of unprotected left main disease. A meta-analysis of randomized controlled trials
    S Desch
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Strumpellstrasse 39, Leipzig, Germany
    Herz 38:48-56. 2013
  3. ncbi Reliability of myocardial salvage assessment by cardiac magnetic resonance imaging in acute reperfused myocardial infarction
    Steffen Desch
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Strümpellstr 39, 04289 Leipzig, Germany
    Int J Cardiovasc Imaging 28:263-72. 2012
  4. ncbi Effect of coronary collaterals on microvascular obstruction as assessed by magnetic resonance imaging in patients with acute ST-elevation myocardial infarction treated by primary coronary intervention
    Steffen Desch
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Germany
    Am J Cardiol 104:1204-9. 2009
  5. ncbi Randomized comparison of a polymer-free sirolimus-eluting stent versus a polymer-based paclitaxel-eluting stent in patients with diabetes mellitus: the LIPSIA Yukon trial
    Steffen Desch
    Department of Internal Medicine Cardiology, University of Leipzig, Heart Center, Leipzig, Germany
    JACC Cardiovasc Interv 4:452-9. 2011
  6. ncbi Prevalence and clinical impact of left coronary dominance in patients with aortic stenosis
    Steffen Desch
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Leipzig, Germany
    J Heart Valve Dis 20:23-8. 2011
  7. ncbi Cardiac magnetic resonance imaging parameters as surrogate endpoints in clinical trials of acute myocardial infarction
    Steffen Desch
    University of Leipzig Heart Center, Department of Internal Medicine Cardiology, Leipzig, Germany
    Trials 12:204. 2011
  8. ncbi Effect of coronary collaterals on long-term prognosis in patients undergoing primary angioplasty for acute ST-elevation myocardial infarction
    Steffen Desch
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Germany
    Am J Cardiol 106:605-11. 2010
  9. ncbi Effect of cocoa products on blood pressure: systematic review and meta-analysis
    Steffen Desch
    Department of Cardiology, University of Leipzig Heart Center, Leipzig, Germany
    Am J Hypertens 23:97-103. 2010
  10. ncbi Platelet inhibition and GP IIb/IIIa receptor occupancy by intracoronary versus intravenous bolus administration of abciximab in patients with ST-elevation myocardial infarction
    Steffen Desch
    Department of Internal Medicine Cardiology, Heart Center, University of Leipzig, Strümpellstr 39, 04289, Leipzig, Germany
    Clin Res Cardiol 101:117-24. 2012

Detail Information

Publications42

  1. ncbi Low vs. higher-dose dark chocolate and blood pressure in cardiovascular high-risk patients
    Steffen Desch
    Department of Cardiology, University of Leipzig Heart Center, Leipzig, Germany
    Am J Hypertens 23:694-700. 2010
    ..higher doses of dark chocolate over the course of 3 months...
  2. ncbi Bypass surgery versus percutaneous coronary intervention for the treatment of unprotected left main disease. A meta-analysis of randomized controlled trials
    S Desch
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Strumpellstrasse 39, Leipzig, Germany
    Herz 38:48-56. 2013
    ..We performed a meta-analysis of randomized controlled trials to compare coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) for the treatment of de novo unprotected left main disease...
  3. ncbi Reliability of myocardial salvage assessment by cardiac magnetic resonance imaging in acute reperfused myocardial infarction
    Steffen Desch
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Strümpellstr 39, 04289 Leipzig, Germany
    Int J Cardiovasc Imaging 28:263-72. 2012
    ..Further validation studies and trials showing the prognostic value of myocardial salvage by CMRI are needed before routine implementation as a surrogate endpoint in STEMI trials...
  4. ncbi Effect of coronary collaterals on microvascular obstruction as assessed by magnetic resonance imaging in patients with acute ST-elevation myocardial infarction treated by primary coronary intervention
    Steffen Desch
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Germany
    Am J Cardiol 104:1204-9. 2009
    ..5% vs 12.2%, p = 0.07). In conclusion, well-developed collaterals before reperfusion by PCI in patients with STEMI are associated with a protective effect on coronary microcirculation...
  5. ncbi Randomized comparison of a polymer-free sirolimus-eluting stent versus a polymer-based paclitaxel-eluting stent in patients with diabetes mellitus: the LIPSIA Yukon trial
    Steffen Desch
    Department of Internal Medicine Cardiology, University of Leipzig, Heart Center, Leipzig, Germany
    JACC Cardiovasc Interv 4:452-9. 2011
    ....
  6. ncbi Prevalence and clinical impact of left coronary dominance in patients with aortic stenosis
    Steffen Desch
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Leipzig, Germany
    J Heart Valve Dis 20:23-8. 2011
    ....
  7. ncbi Cardiac magnetic resonance imaging parameters as surrogate endpoints in clinical trials of acute myocardial infarction
    Steffen Desch
    University of Leipzig Heart Center, Department of Internal Medicine Cardiology, Leipzig, Germany
    Trials 12:204. 2011
    ..Randomized controlled trials of acute myocardial infarction which have used CMR parameters as a primary endpoint are presented...
  8. ncbi Effect of coronary collaterals on long-term prognosis in patients undergoing primary angioplasty for acute ST-elevation myocardial infarction
    Steffen Desch
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Germany
    Am J Cardiol 106:605-11. 2010
    ..In conclusion, the presence of a well-developed collateral network before mechanical reperfusion in patients with STEMI is associated with improved long-term survival and lower major adverse cardiovascular event rates...
  9. ncbi Effect of cocoa products on blood pressure: systematic review and meta-analysis
    Steffen Desch
    Department of Cardiology, University of Leipzig Heart Center, Leipzig, Germany
    Am J Hypertens 23:97-103. 2010
    ..Cocoa products such as dark chocolate and cocoa beverages may have blood pressure (BP)-lowering properties due to their high content of plant-derived flavanols...
  10. ncbi Platelet inhibition and GP IIb/IIIa receptor occupancy by intracoronary versus intravenous bolus administration of abciximab in patients with ST-elevation myocardial infarction
    Steffen Desch
    Department of Internal Medicine Cardiology, Heart Center, University of Leipzig, Strümpellstr 39, 04289, Leipzig, Germany
    Clin Res Cardiol 101:117-24. 2012
    ....
  11. ncbi Right ventricular injury in ST-elevation myocardial infarction: risk stratification by visualization of wall motion, edema, and delayed-enhancement cardiac magnetic resonance
    Matthias Grothoff
    Department of Radiology, University of Leipzig Heart Center, Leipzig, Germany
    Circ Cardiovasc Imaging 5:60-8. 2012
    ..Aims were to determine the predictors and the prognostic significance of RVI assessed by wall motion abnormalities, edema, myocardial salvage index, and delayed enhancement in acute reperfused STEMI...
  12. ncbi Myocardium at risk in ST-segment elevation myocardial infarction comparison of T2-weighted edema imaging with the MR-assessed endocardial surface area and validation against angiographic scoring
    Georg Fuernau
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Leipzig, Germany
    JACC Cardiovasc Imaging 4:967-76. 2011
    ....
  13. ncbi Sex differences in myocardial salvage and clinical outcome in patients with acute reperfused ST-elevation myocardial infarction: advances in cardiovascular imaging
    Ingo Eitel
    University of Leipzig, Heart Center, Department of Internal Medicine Cardiology, Leipzig, Germany
    Circ Cardiovasc Imaging 5:119-26. 2012
    ....
  14. ncbi Optimal timing of invasive angiography in stable non-ST-elevation myocardial infarction: the Leipzig Immediate versus early and late PercutaneouS coronary Intervention triAl in NSTEMI (LIPSIA-NSTEMI Trial)
    Holger Thiele
    Department of Internal Medicine Cardiology, Heart Center, University of Leipzig, Strümpellstr 39, 04289 Leipzig, Germany
    Eur Heart J 33:2035-43. 2012
    ..The aim of this multicentre trial was to assess whether an immediate invasive approach is superior to an early invasive or a selective invasive approach with respect to reduction of large infarction...
  15. ncbi Relationship and prognostic value of microvascular obstruction and infarct size in ST-elevation myocardial infarction as visualized by magnetic resonance imaging
    Suzanne de Waha
    Department of Internal Medicine, Cardiology, University of Leipzig Heart Center, Strümpellstr 39, Leipzig, 04289, Germany
    Clin Res Cardiol 101:487-95. 2012
    ..We hypothesized that a ratio of MO and infarct size (MO/infarct size) might be an even stronger predictor for outcome after STEMI, which has not been investigated yet...
  16. ncbi Prognostic value and determinants of a hypointense infarct core in T2-weighted cardiac magnetic resonance in acute reperfused ST-elevation-myocardial infarction
    Ingo Eitel
    University of Leipzig Heart Center, Department of Internal Medicine Cardiology, Leipzig, Germany
    Circ Cardiovasc Imaging 4:354-62. 2011
    ..The aim of this study was to evaluate determinants and prognostic impact of a hypointense infarct core in T2-weighted CMR images, studied in patients after acute, reperfused ST-elevation-myocardial infarction...
  17. ncbi Prognostic significance and determinants of myocardial salvage assessed by cardiovascular magnetic resonance in acute reperfused myocardial infarction
    Ingo Eitel
    Heart Center, Department of Internal Medicine Cardiology, University of Leipzig, Leipzig, Germany
    J Am Coll Cardiol 55:2470-9. 2010
    ..The aim of the study was to determine the prognostic significance and determinants of myocardial salvage assessed by cardiovascular magnetic resonance (CMR) in reperfused ST-segment elevation myocardial infarction...
  18. ncbi Impact of N-acetylcysteine on contrast-induced nephropathy defined by cystatin C in patients with ST-elevation myocardial infarction undergoing primary angioplasty
    Michal Droppa
    Department of Internal Medicine Cardiology, University of Leipzig, Heart Center, Leipzig, Germany
    Clin Res Cardiol 100:1037-43. 2011
    ....
  19. ncbi Incidence and distribution of occluded culprit arteries and impact of coronary collaterals on outcome in patients with non-ST-segment elevation myocardial infarction and early invasive treatment strategy
    Philipp Bahrmann
    Department of Internal Medicine Cardiology, University of Leipzig, Heart Center, 04289, Leipzig, Germany
    Clin Res Cardiol 100:457-67. 2011
    ..In addition, coronary collaterals may have beneficial effects in patients with OCA...
  20. ncbi Relation of circulating MicroRNA-133a concentrations with myocardial damage and clinical prognosis in ST-elevation myocardial infarction
    Ingo Eitel
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Leipzig, Germany Electronic address
    Am Heart J 164:706-14. 2012
    ..The aims of this study were (1) to assess the relation between miR-133a and myocardial damage assessed by cardiovascular magnetic resonance (CMR) imaging and (2) to evaluate the prognostic value of miR-133a in reperfused STEMI...
  21. ncbi Diagnostic performance of CMR imaging compared with EMB in patients with suspected myocarditis
    Philipp Lurz
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Leipzig, Germany
    JACC Cardiovasc Imaging 5:513-24. 2012
    ..The goal of this study was to assess the diagnostic performance of cardiac magnetic resonance (CMR) compared with endomyocardial biopsy in patients with suspected acute myocarditis (AMC) and chronic myocarditis (CMC)...
  22. ncbi Time-dependency, predictors and clinical impact of infarct transmurality assessed by magnetic resonance imaging in patients with ST-elevation myocardial infarction reperfused by primary coronary percutaneous intervention
    Suzanne de Waha
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Strümpellstr 39, 04289, Leipzig, Germany
    Clin Res Cardiol 101:191-200. 2012
    ..However, transmural infarction was not predictive of death and congestive heart failure...
  23. ncbi Prognostic impact of hyperglycemia in nondiabetic and diabetic patients with ST-elevation myocardial infarction: insights from contrast-enhanced magnetic resonance imaging
    Ingo Eitel
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Leipzig, Germany
    Circ Cardiovasc Imaging 5:708-18. 2012
    ..However, hyperglycemia has a stronger relationship to myocardial injury in nondiabetic compared with diabetic patients...
  24. ncbi Intraaortic balloon support for myocardial infarction with cardiogenic shock
    Holger Thiele
    University of Leipzig Heart Center, Department of Internal Medicine Cardiology, Leipzig, Germany
    N Engl J Med 367:1287-96. 2012
    ..However, evidence is based mainly on registry data, and there is a paucity of randomized clinical trials...
  25. ncbi Impact of high-dose N-acetylcysteine versus placebo on contrast-induced nephropathy and myocardial reperfusion injury in unselected patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. The LIPSIA-
    Holger Thiele
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Leipzig, Germany
    J Am Coll Cardiol 55:2201-9. 2010
    ....
  26. ncbi Intracoronary versus intravenous bolus abciximab application in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention: 6-month effects on infarct size and left ventricular function. The randomised Leipzig I
    Ingo Eitel
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Strümpellstr 39, 04289, Leipzig, Germany
    Clin Res Cardiol 100:425-32. 2011
    ..Aim of this study was to investigate whether the early benefits of an IC abciximab administration in STEMI patients undergoing PCI are sustained at 6 months...
  27. ncbi Impact of early vs. late microvascular obstruction assessed by magnetic resonance imaging on long-term outcome after ST-elevation myocardial infarction: a comparison with traditional prognostic markers
    Suzanne de Waha
    Department of Internal Medicine Cardiology, University of Leipzig Heart Centre, Leipzig, Germany
    Eur Heart J 31:2660-8. 2010
    ..Furthermore, it is unclear whether the assessment of MO by MRI adds incremental prognostic information independent of traditional outcome markers...
  28. ncbi Long-term prognostic value of myocardial salvage assessed by cardiovascular magnetic resonance in acute reperfused myocardial infarction
    Ingo Eitel
    Department of Internal Medicine, University of Leipzig, Heart Center, Leipzig, Germany
    Heart 97:2038-45. 2011
    ....
  29. ncbi Randomized comparison of pre-hospital-initiated facilitated percutaneous coronary intervention versus primary percutaneous coronary intervention in acute myocardial infarction very early after symptom onset: the LIPSIA-STEMI trial (Leipzig immediate preho
    Holger Thiele
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Leipzig, Germany
    JACC Cardiovasc Interv 4:605-14. 2011
    ....
  30. ncbi Growth-differentiation factor 15 as predictor of mortality in acute reperfused ST-elevation myocardial infarction: insights from cardiovascular magnetic resonance
    Ingo Eitel
    Department of Internal Medicine Cardiology, University of Leipzig, Heart Center, Strumpellstrasse 39, Leipzig 04289, Germany
    Heart 97:632-40. 2011
    ....
  31. ncbi What is the evidence for IABP in STEMI with and without cardiogenic shock?
    Suzanne de Waha
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Strumpellstrasse 39, 04289 Leipzig, Germany
    Ther Adv Cardiovasc Dis 6:123-32. 2012
    ..Although recent meta-analyses challenge current AHA/ACC/ESC guidelines, adequately powered randomized studies are needed to elucidate the role of IABP in patients with acute myocardial infarction complicated by cardiogenic shock...
  32. ncbi Timing of invasive treatment after fibrinolysis in ST elevation myocardial infarction--a meta-analysis of immediate or early routine versus deferred or ischemia-guided randomised controlled trials
    Steffen Desch
    Department of Internal Medicine Cardiology, University of Leipzig Heart Centre, Strümpellstr 39, Leipzig 04289, Germany
    Heart 96:1695-702. 2010
    ..There were no significant differences in the risk of stroke or major bleeding. Conclusions These results support the current recommendation of a routine early invasive strategy in STEMI patients after successful fibrinolysis...
  33. ncbi Endothelin-1 release in acute myocardial infarction as a predictor of long-term prognosis and no-reflow assessed by contrast-enhanced magnetic resonance imaging
    Ingo Eitel
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Germany
    Am Heart J 159:882-90. 2010
    ..The aim of our study was to assess the relationship between systemic ET-1 levels and the occurrence of no-reflow as well as to evaluate the prognostic value of ET-1 in a high-risk STEMI population...
  34. ncbi Aborted myocardial infarction in intracoronary compared with standard intravenous abciximab administration in patients undergoing primary percutaneous coronary intervention for ST-elevation myocardial infarction
    Ingo Eitel
    University of Leipzig, Heart Center, Department of Internal Medicine, Cardiology, Leipzig Germany
    Int J Cardiol 153:21-5. 2011
    ..So far the occurrence of aborted MI, a new therapeutic target of effective treatment in STEMI, has not been evaluated in IC versus IV abciximab administration in STEMI patients undergoing primary PCI...
  35. ncbi Intracoronary versus intravenous bolus abciximab during primary percutaneous coronary intervention in patients with acute ST-elevation myocardial infarction: a randomised trial
    Holger Thiele
    Universität Leipzig Heart Centre, Department of Internal Medicine Cardiology, Leipzig, Germany
    Lancet 379:923-31. 2012
    ..However, the safety and efficacy of intracoronary versus standard intravenous bolus application in patients with ST-elevation myocardial infarction (STEMI) undergoing this intervention has not been tested in a large-scale clinical trial...
  36. ncbi Prognostic significance and magnetic resonance imaging findings in aborted myocardial infarction after primary angioplasty
    Ingo Eitel
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Germany
    Am Heart J 158:806-13. 2009
    ..So far, the prognostic significance and magnetic resonance imaging (MRI) findings of an aborted MI after primary angioplasty have not been evaluated appropriately...
  37. ncbi Comparison of bare-metal stenting with minimally invasive bypass surgery for stenosis of the left anterior descending coronary artery: 10-year follow-up of a randomized trial
    Stephan Blazek
    Department of Internal Medicine, Cardiology, University of Leipzig Heart Center, Strumpellstrasse 39, Leipzig, Germany
    JACC Cardiovasc Interv 6:20-6. 2013
    ....
  38. ncbi Intraaortic balloon counterpulsation in acute myocardial infarction complicated by cardiogenic shock: design and rationale of the Intraaortic Balloon Pump in Cardiogenic Shock II (IABP-SHOCK II) trial
    Holger Thiele
    University of Leipzig Heart Center, Leipzig, Germany
    Am Heart J 163:938-45. 2012
    ..The hypothesis of this trial is that IABP in addition to early revascularization by either percutaneous coronary intervention or coronary artery bypass grafting will improve clinical outcome of patients in cardiogenic shock...
  39. ncbi Clinical characteristics and cardiovascular magnetic resonance findings in stress (takotsubo) cardiomyopathy
    Ingo Eitel
    University of Leipzig Heart Center, Department of Internal Medicine Cardiology, Strumpellstrasse 39, 04289 Leipzig, Germany
    JAMA 306:277-86. 2011
    ..Various aspects of its clinical profile have been described in small single-center populations, but larger, multicenter data sets have been lacking so far. Furthermore, it remains difficult to quickly establish diagnosis on admission...
  40. ncbi Randomized comparison of percutaneous coronary intervention with sirolimus-eluting stents versus coronary artery bypass grafting in unprotected left main stem stenosis
    Enno Boudriot
    Department of Internal Medicine Cardiology, University of Leipzig Heart Center, Germany
    J Am Coll Cardiol 57:538-45. 2011
    ..The purpose of this randomized study was to compare sirolimus-eluting stenting with coronary artery bypass grafting (CABG) for patients with unprotected left main (ULM) coronary artery disease...
  41. ncbi Effect of carotid artery stenting on the release of S-100B and neurone-specific enolase
    Christiane Mattusch
    University of Leipzig Heart Center, Department of Internal Medicine Cardiology, Germany
    Angiology 62:376-80. 2011
    ..Neither patients with CAS nor those undergoing diagnostic angiography displayed any significant changes in serial NSE levels...
  42. ncbi Intracoronary compared with intravenous bolus abciximab application during primary percutaneous coronary intervention in ST-segment elevation myocardial infarction: cardiac magnetic resonance substudy of the AIDA STEMI trial
    Ingo Eitel
    Heart Center, Department of Internal Medicine, Cardiology, University of Leipzig, Leipzig, Germany
    J Am Coll Cardiol 61:1447-54. 2013
    ....