Research Topics
Species | Thomas MentzelSummaryAffiliation: Dermatopathologische Gemeinschaftspraxis Country: Germany Publications
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Publications
Malignant dermatofibroma: clinicopathological, immunohistochemical, and molecular analysis of seven casesThomas Mentzel
Dermatopathology Bodensee Friedrichshafen, Friedrichshafen, Germany
Mod Pathol 26:256-67. 2013..Five neoplasms showed chromosomal aberrations by array-CGH, suggesting that these changes may represent an additional diagnostic tool in the recognition of cases of dermatofibroma with a metastatic potential...
Postradiation cutaneous angiosarcoma after treatment of breast carcinoma is characterized by MYC amplification in contrast to atypical vascular lesions after radiotherapy and control cases: clinicopathological, immunohistochemical and molecular analysis oT Mentzel
Dermatopathologie Bodensee, Friedrichshafen, Germany
Mod Pathol 25:75-85. 2012..Immunohistochemical stainings for MYC are useful for mapping of these lesions and for careful tumor margin control...
Intravascular leiomyosarcoma of the brachiocephalic region -- report of an unusual tumour localisation: case report and review of the literatureDaniel Johannes Tilkorn
Department of Plastic Surgery, Burn Center, Hand Center, Sarcoma Reference Center, BG University Hospital Bergmannsheil, Ruhr University Bochum, Germany
World J Surg Oncol 6:113. 2008..Intravascular leiomyosarcoma is a rare tumour entity originating from venous vessel structures and most frequently affecting the inferior vena cava...
[Spindle cell rhabdomyosarcoma in adults: a new entity in the spectrum of malignant mesenchymal tumors of soft tissues]T Mentzel
Dermatopathologie Bodensee, 88048, Friedrichshafen, Deutschland
Pathologe 31:91-6. 2010....
Well-differentiated spindle cell liposarcoma ('atypical spindle cell lipomatous tumor') does not belong to the spectrum of atypical lipomatous tumor but has a close relationship to spindle cell lipoma: clinicopathologic, immunohistochemical, and molecularThomas Mentzel
Dermatopathologie, Friedrichshafen, Germany
Mod Pathol 23:729-36. 2010....
Dermatomyofibroma: clinicopathologic and immunohistochemical analysis of 56 cases and reappraisal of a rare and distinct cutaneous neoplasmThomas Mentzel
Dermatopathologie Bodensee, Friedrichshafen, Germany
Am J Dermatopathol 31:44-9. 2009..Dermatomyofibroma represents a benign fibroblastic/myofibroblastic dermal neoplasm...
[Uncommon variants of malignant melanocytic neoplasms]T Mentzel
Dermatopathologische Gemeinschaftspraxis, Friedrichshafen, Siemensstrasse 6 1, 88048, Friedrichshafen
Pathologe 28:445-52. 2007....
Sarcomas of the skin in the elderlyThomas Mentzel
Department of Dermatopathologie Bodensee, Siemensstrasse 6 1, D 88048 Friedrichshafen, Germany
Clin Dermatol 29:80-90. 2011....
[Skin tumors as marker lesions for tumor syndromes]T Mentzel
Dermatopathologie, Friedrichshafen, Siemensstr 6 1, 88048, Friedrichshafen
Pathologe 31:489-96. 2010....
Mixed-type liposarcoma: clinicopathological, immunohistochemical, and molecular analysis of a case arising in deep soft tissues of the lower extremityThomas Mentzel
Dermatopathologische Gemeinschaftspraxis, Siemensstrasse 6 1, 88048, Friedrichshafen, Germany
Virchows Arch 453:197-201. 2008....
Myxoid dermatofibrosarcoma protuberans: clinicopathologic, immunohistochemical, and molecular analysis of eight casesThomas Mentzel
Dermatopathologische Gemeinschaftspraxis, Friedrichshafen, Germany
Am J Dermatopathol 29:443-8. 2007....
[Epithelioid sarcoma: morphologic variants and differential diagnosis]T Mentzel
Dermatopathologie Bodensee, Siemensstr 6 1, 88048, Friedrichshafen, Deutschland
Pathologe 31:135-41. 2010....
Plaque-like CD34-positive dermal fibroma ("medallion-like dermal dendrocyte hamartoma"): clinicopathologic, immunohistochemical, and molecular analysis of 5 cases emphasizing its distinction from superficial, plaque-like dermatofibrosarcoma protHeinz Kutzner
Dermatopathologie Friedrichshafen, Siemensstrasse 6 1, 88048 Friedrichshafen, Germany
Am J Surg Pathol 34:190-201. 2010..In archival formalin-fixed paraffin-embedded tissue, however, FISH analysis is more robust and exhibits a higher clinical sensitivity than RT-PCR...
Histological and genetic evidence for a variant of superficial spreading melanoma composed predominantly of large nestsHeinz Kutzner
Dermatopathologie Friedrichshafen, Friedrichshafen, Germany
Mod Pathol 25:838-45. 2012..Awareness of the histological features will aid in their correct diagnosis as melanoma, and in difficult cases, judicious application of ancillary tests such as aCGH (rather than FISH) will assist accurate diagnosis...
Cutaneous clear cell sarcoma: a clinicopathologic, immunohistochemical, and molecular analysis of 12 cases emphasizing its distinction from dermal melanomaMarkus Hantschke
Dermatopathologie Fried richshafen, Siemensstrasse 6 1, D 88048 Friedrichshafen, Germany
Am J Surg Pathol 34:216-22. 2010..The specific translocation pattern was confirmed in all cases by fluorescence in situ hybridization. Local recurrences and metastases developed in 2 and 3 patients, respectively, and 1 patient died of the disease...
Primary cutaneous marginal zone B-cell lymphoma may exhibit both the t(14;18)(q32;q21) IGH/BCL2 and the t(14;18)(q32;q21) IGH/MALT1 translocation: an indicator for clonal transformation towards higher-grade B-cell lymphoma?Gabriele Palmedo
DermPath, Friedrichshafen, Germany
Am J Dermatopathol 29:231-6. 2007..Therefore, the etiopathogenetic relevance of either translocation in PCMZL remains a matter of debate...
The T1796A mutation of the BRAF gene is absent in Spitz neviGabriele Palmedo
Dermatopathologische Gemeinschaftspraxis, Friedrichshafen, Germany
J Cutan Pathol 31:266-70. 2004..The T1796A mutation has been shown to promote cell proliferation...
Primary cutaneous cribriform apocrine carcinoma: a clinicopathologic and immunohistochemical study of 26 cases of an under-recognized cutaneous adnexal neoplasmArno Rutten
Dermatohistopathologische Gemeinschaftspraxis, Friedrichshafen, Germany
J Am Acad Dermatol 61:644-51. 2009..Cribriform carcinoma is the histopathologic variant of cutaneous apocrine carcinoma characterized by interconnected solid aggregations of neoplastic cells that are punctuated by small round spaces...
Reticular and plexiform perineurioma: clinicopathological and immunohistochemical analysis of two cases and review of perineurial neoplasms of skin and soft tissuesThomas Mentzel
Dermatopathologische Gemeinschaftspraxis, Siemensstrasse 6/1, 88048, Friedrichshafen, Germany
Virchows Arch 447:677-82. 2005..The morphological spectrum and the differential diagnosis of perineurial neoplasms of skin and soft tissues are discussed...
Follicular malignant melanoma: a variant of melanoma to be distinguished from lentigo maligna melanomaMarkus Hantschke
Dermatopathologische Gemeinschaftspraxis, Siemensstrasse 6/1, D-88048 Friedrichshafen, Germany
Am J Dermatopathol 26:359-63. 2004..Superficial shave excision or even laser treatment in these specific cases may lead to a fatal prognosis for the patient...
Myopericytoma of skin and soft tissues: clinicopathologic and immunohistochemical study of 54 casesThomas Mentzel
Dermatopathologische Gemeinschaftspraxis, Siemensstrasse 6/1, D-88048 Friedrichshafen, Germany
Am J Surg Pathol 30:104-13. 2006..Most cases of myopericytoma behave in a benign fashion, but local recurrences and rarely metastases may occur in atypical and malignant neoplasms...
Spindle cell rhabdomyosarcoma in adults: clinicopathological and immunohistochemical analysis of seven new casesThomas Mentzel
Dermatopathologische Gemeinschaftspraxis, Siemenstrasse 6/1, 88048 Friedrichshafen, Germany
Virchows Arch 449:554-60. 2006....
Atypical lipomatous tumor/"well-differentiated liposarcoma" of the skin clinically presenting as a skin tag: clinicopathologic, immunohistochemical, and molecular analysis of 2 casesBruno E Paredes
Dermatopathologie Friedrichshafen, Bodensee, Germany
Am J Dermatopathol 33:603-7. 2011..None of the cases recurred after surgical treatment. These 2 cases show the importance of not to misdiagnose lesions which clinically may appear to be benign...
Spindle cell predominant trichodiscoma: a fibrofolliculoma/trichodiscoma variant considered formerly to be a neurofollicular hamartoma: a clinicopathological and immunohistochemical analysis of 17 casesHeinz Kutzner
Dermatopathologische Gemeinschaftspraxis, Friedrichshafen, Germany
Am J Dermatopathol 28:1-8. 2006..We therefore propose the new term spindle cell predominant trichodiscoma (SCPT) for this particular variant of the morphologic fibrofolliculoma/trichodiscoma spectrum...
Cutaneous myoepithelial neoplasms: clinicopathologic and immunohistochemical study of 20 cases suggesting a continuous spectrum ranging from benign mixed tumor of the skin to cutaneous myoepithelioma and myoepithelial carcinomaThomas Mentzel
Dermatopathologisches Gemeinschaftslabor, Friedrichshafen, Germany
J Cutan Pathol 30:294-302. 2003..Further studies with extended follow-up information are necessary to establish prognostic factors...
Haemorrhagic dermatomyofibroma (plaque-like dermal fibromatosis): clinicopathological and immunohistochemical analysis of three cases resembling plaque-stage Kaposi's sarcomaT Mentzel
Dermatopathologisches Gemeinschaftslabor, Friedrichshafen, Germany
Histopathology 42:594-8. 2003..CONCLUSIONS: The reported cases widen the clinicopathological spectrum of dermatomyofibroma and emphasize plaque-stage Kaposi's sarcoma as an additional differential diagnosis...
[Perivascular neoplasms of skin and soft tissues. A review]T Mentzel
Dermatopathologische Gemeinschaftspraxis, Friedrichshafen
Pathologe 26:134-45. 2005..PEComas represent an enigmatic family of neoplasms composed of perivascular epithelioid, clear, and spindled tumour cells characterized by a coexpression of melanocytic and myogenic markers...
Vascular congenital dermatofibrosarcoma protuberans: a new histological variant of dermatofibrosarcoma protuberansIliana Tantcheva-Poor
Department of Dermatology, University of Cologne, Cologne, Germany
Am J Dermatopathol 34:e46-9. 2012..This unique variant represents a potential pitfall for dermatopathologists and underlines the importance of cytogenetic diagnostics in unusual cases of DFSP...
[Cutaneous perineurioma. Clinical and histological findings and differential diagnosis]T Mentzel
Dermatopathologische Gemeinschaftspraxis, Friedrichshafen
Pathologe 24:207-13. 2003..The differential diagnosis of various variants of cutaneous perineurioma from other mesenchymal lesions as well as melanocytic and epithelial neoplasms is discussed...
[Myoepithelial neoplasms of skin and soft tissues]T Mentzel
Dermatopathologische Gemeinschaftspraxis, Friedrichshafen
Pathologe 26:322-30. 2005..The presence of at least moderate cytological atypia is associated with a significant risk for aggressive behavior and propensity for metastasis...
Cutaneous myoepithelioma: an under-recognized cutaneous neoplasm composed of myoepithelial cellsH Kutzner
Dermatohistopathologisches Gemeinschaftslabor, Friedrichshafen, Germany, Graz University, Graz, Austria
Am J Surg Pathol 25:348-55. 2001..The findings in this report expand the clinical and histopathologic spectrum of cutaneous myoepithelioma, an under-recognized cutaneous neoplasm of myoepithelial cells...
Cutaneous lipomatous neoplasmsT Mentzel
Dermatohistopathologische Gemeinschaftspraxis, Friedrichshafen, Germany
Semin Diagn Pathol 18:250-7. 2001..Rarely, liposarcoma may occur as a purely cutaneous lesion with a favorable clinical prognosis despite high-grade morphologic features in many cases...
Benign fibrous histiocytoma (dermatofibroma) of the face: clinicopathologic and immunohistochemical study of 34 cases associated with an aggressive clinical courseT Mentzel
Department of Dermatohistopathology, Friedrichshafen, Germany
Am J Dermatopathol 23:419-26. 2001....
[Diffuse dermal angiomatosis]H Kutzner
Dermatohistopathologische Gemeinschaftspraxis, Friedrichshafen, Germany
Hautarzt 53:808-12. 2002..DDA regressed spontaneously within 12 weeks, and has not recurred over 4 years of follow-up...
Palmar atypical lipomatous tumour with spindle cell features (well-differentiated spindle cell liposarcoma): a rare neoplasm arising in an unusual anatomical locationT Mentzel
Dermatopathologische Gemeinschaftspraxis, Siemensstrasse 6/1, 88048 Friedrichshafen, Germany
Virchows Arch 446:300-4. 2005..Aypical lipomatous tumour with spindle cell features may arise very rarely in palmar location and has to be distinguished from a number of benign and malignant mesenchymal neoplasms...
[Skin adnexal and salivary gland neoplasms. Similarities and differences of selected patients]T Mentzel
Dermatopathologische Gemeinschaftspraxis, Friedrichshafen
Pathologe 25:79-88. 2004..malignant myoepithelioma of salivary glands), cutaneous adenoid cystic carcinoma (vs. adenoid cystic carcinoma of salivary glands), and mucinous eccrine carcinoma (vs. mucous carcinoma of salivary glands)...
CD34-positive glomus tumor: clinicopathologic and immunohistochemical analysis of six cases with myxoid stromal changesThomas Mentzel
Dermatohistopathologisches Gemeinschaftslabor, Siemensstrasse 6/1, D-88048 Friedrichshafen, Germany
J Cutan Pathol 29:421-5. 2002..CONCLUSIONS: Neoplastic cells in glomus tumor may show a coexpression of alpha-smooth muscle actin and CD34, an important finding regarding the differential diagnosis of these lesions and the relationship of perivascular neoplasms...
Mutations of the BRAF gene in benign and malignant melanocytic lesionsAmir S Yazdi
Department of Dermatology, Ludwig-Maximilians-University, Munich, Germany
J Invest Dermatol 121:1160-2. 2003..In conclusion, mutations in exon 15 of the BRAF gene are nonspecific for progression of a nevus to a melanoma. Other so far unknown cofactors seem to be of importance...
Hobnail hemangiomas (targetoid hemosiderotic hemangiomas) are true lymphangiomasFolker E Franke
Department of Pathology, Justus Liebig University of Giessen, Langhanstrasse 10, D 35392 Giessen, Germany
J Cutan Pathol 31:362-7. 2004..In contrast to its well-characterized histology, it has been unclear whether this tumor arises from blood vessel endothelial cells (BECs) or lymphatic vessel endothelial cells (LECs)...
Congenital hand lesionEduardo Calonje
Department of Histopathology, St. John's Institute of Dermatology, St. Thomas' Hospital, London, United Kingdom
Am J Dermatopathol 29:588-90. 2007
Mucinous carcinoma of the skin, primary, and secondary: a clinicopathologic study of 63 cases with emphasis on the morphologic spectrum of primary cutaneous forms: homologies with mucinous lesions in the breastDmitry V Kazakov
Sikl's Department of Pathology, Charles University, Medical Faculty Hospital, Alej Svobody 80, 304-60 Pilsen, Czech Republic
Am J Surg Pathol 29:764-82. 2005..Dirty necrosis was a constant histologic finding in intestine mucinous carcinomas involving the skin, and this feature may serve as a clue to an intestinal origin...
Tubular adenoma and syringocystadenoma papilliferum: a reappraisal of their relationship. An interobserver study of a series, by a panel of dermatopathologistsDmitry V Kazakov
Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Pilsen, Czech Republic
Am J Dermatopathol 29:256-63. 2007....
Benign vascular proliferations in irradiated skinLuis Requena
Department of Dermatology, Fundacion Jimenez Diaz, Universidad Autonoma, Madrid, Spain
Am J Surg Pathol 26:328-37. 2002....
Acquired elastotic hemangioma: A clinicopathologic variant of hemangiomaLuis Requena
Department of Dermatology, , , Madrid, Spain
J Am Acad Dermatol 47:371-6. 2002..On histopathologic examination, it is characterized by capillary proliferation involving the dermis...
Clear cell trichoblastoma: a clinicopathological and ultrastructural study of two casesDmitry V Kazakov
Sikl s Department of Pathology, Charles University Medical Faculty Hospital, Pilsen, Czech Republic
Am J Dermatopathol 28:197-201. 2006..No distinct lipid droplets or glycogen particles were identified. The basaloid cells were joined by scattered small desmosomes. These findings were consistent with trichilemmal differentiation at the bulb...
Atypical lipomatous tumor in a 14-year-old patient: distinction from lipoblastoma using FISH analysisCornelius Kuhnen
Institute for Pathology, University Hospital Bergmannsheil, Burkle de la Camp Platz 1, 44789 Bochum, Germany
Virchows Arch 441:299-302. 2002..This case shows that FISH can serve as a decisive tool in the differential diagnosis of lipoblastoma and lipoma-like liposarcoma apart from its role in distinction between lipoblastoma and myxoid/round cell liposarcoma...
Proliferating trichilemmal tumors: clinicopathologic evaluation is a guide to biologic behaviorAndrew L Folpe
Emory University, Atlanta, GA, USA
J Cutan Pathol 30:492-8. 2003..The malignant potential of PTT is controversial, as only a small number of histologically malignant PTTs and a smaller number of clinically malignant PTTs have been reported...
Most osteomalacia-associated mesenchymal tumors are a single histopathologic entity: an analysis of 32 cases and a comprehensive review of the literatureAndrew L Folpe
Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA, USA
Am J Surg Pathol 28:1-30. 2004..Recognition of PMTMCT is critical, as complete resection cures intractable OO. Immunohistochemistry and RT-PCR for FGF-23 confirm the role of this protein in PMTMCT-associated OO...
Dedifferentiated liposarcoma with extensive lymphoid componentCornelius Kuhnen
Institute for Pathology, Limb tumor registry, Ruhr University, University Hospital Bergmannsheil, Burkle de la Camp Platz 1, D 44789 Bochum, Germany
Pathol Res Pract 201:347-53. 2005..An extensive lymphoid "overgrowth" must be considered within the spectrum of unusual variants and in the differential diagnosis of dedifferentiated liposarcoma...
Primary and metastatic high-grade pleomorphic sarcoma/malignant fibrous histiocytoma of the gastrointestinal tract: an approach to the differential diagnosis in a series of five cases with emphasis on myofibroblastic differentiationAbbas Agaimy
Institute of Pathology, Klinikum Nürnberg, Prof Ernst Nathan Strasse 1, 90419 Nurnberg, Germany
Virchows Arch 451:949-57. 2007..They should be distinguished from a variety of primary and metastatic pleomorphic neoplasms, in particular high-grade sarcomatous GI stromal tumours (GIST), pleomorphic leiomyosarcoma, sarcomatoid carcinoma and other mimics...
