Karin Dedek

Summary

Country: Germany

Publications

  1. pmc Testing for a gap junction-mediated bystander effect in retinitis pigmentosa: secondary cone death is not altered by deletion of connexin36 from cones
    Katharina Kranz
    Department of Neurobiology, University of Oldenburg, Oldenburg, Germany
    PLoS ONE 8:e57163. 2013
  2. doi request reprint A novel type of interplexiform amacrine cell in the mouse retina
    Karin Dedek
    Department of Neurobiology, University of Oldenburg, Oldenburg, Germany
    Eur J Neurosci 30:217-28. 2009
  3. doi request reprint Connexin57 is expressed in dendro-dendritic and axo-axonal gap junctions of mouse horizontal cells and its distribution is modulated by light
    Ulrike Janssen-Bienhold
    Department of Neurobiology, University of Oldenburg, D 26111 Oldenburg, Germany
    J Comp Neurol 513:363-74. 2009
  4. ncbi request reprint Localization of heterotypic gap junctions composed of connexin45 and connexin36 in the rod pathway of the mouse retina
    Karin Dedek
    Department of Neurobiology, University of Oldenburg, D 26111 Oldenburg, Germany
    Eur J Neurosci 24:1675-86. 2006
  5. doi request reprint Rod and cone contributions to horizontal cell light responses in the mouse retina
    Jennifer Trümpler
    Department of Neurobiology, Carl von Ossietzky University, D 26111 Oldenburg, Germany
    J Neurosci 28:6818-25. 2008
  6. doi request reprint Expression and modulation of connexin 30.2, a novel gap junction protein in the mouse retina
    Luis Pérez de Sevilla Müller
    Department of Neurobiology, University of Oldenburg, Oldenburg, Germany
    Vis Neurosci 27:91-101. 2010
  7. pmc Ganglion cell adaptability: does the coupling of horizontal cells play a role?
    Karin Dedek
    Department of Neurobiology, University of Oldenburg, Oldenburg, Germany
    PLoS ONE 3:e1714. 2008
  8. doi request reprint Expression of Pannexin1 in the outer plexiform layer of the mouse retina and physiological impact of its knockout
    Katharina Kranz
    Department of Neurobiology, University of Oldenburg, D 26111 Oldenburg, Germany
    J Comp Neurol 521:1119-35. 2013
  9. doi request reprint Subcellular distribution of connexin45 in OFF bipolar cells of the mouse retina
    Gerrit Hilgen
    Department of Neurobiology, University of Oldenburg, Germany
    J Comp Neurol 519:433-50. 2011
  10. pmc Cell-specific cre recombinase expression allows selective ablation of glutamate receptors from mouse horizontal cells
    Sebastian Ströh
    Department of Neurobiology, University of Oldenburg, Oldenburg, Germany
    PLoS ONE 8:e83076. 2013

Collaborators

Detail Information

Publications16

  1. pmc Testing for a gap junction-mediated bystander effect in retinitis pigmentosa: secondary cone death is not altered by deletion of connexin36 from cones
    Katharina Kranz
    Department of Neurobiology, University of Oldenburg, Oldenburg, Germany
    PLoS ONE 8:e57163. 2013
    ....
  2. doi request reprint A novel type of interplexiform amacrine cell in the mouse retina
    Karin Dedek
    Department of Neurobiology, University of Oldenburg, Oldenburg, Germany
    Eur J Neurosci 30:217-28. 2009
    ..A new type of interplexiform ON amacrine cell is described, which is strongly coupled and uses GABA but not dopamine as its neurotransmitter...
  3. doi request reprint Connexin57 is expressed in dendro-dendritic and axo-axonal gap junctions of mouse horizontal cells and its distribution is modulated by light
    Ulrike Janssen-Bienhold
    Department of Neurobiology, University of Oldenburg, D 26111 Oldenburg, Germany
    J Comp Neurol 513:363-74. 2009
    ..This study shows for the first time the detailed location of connexin57 expression within mouse horizontal cells, and provides the first ultrastructural data on mouse horizontal cell gap junctions...
  4. ncbi request reprint Localization of heterotypic gap junctions composed of connexin45 and connexin36 in the rod pathway of the mouse retina
    Karin Dedek
    Department of Neurobiology, University of Oldenburg, D 26111 Oldenburg, Germany
    Eur J Neurosci 24:1675-86. 2006
    ..Our results provide direct evidence for heterotypic gap junctions composed of Cx36 and Cx45 between AII amacrine and certain types of ON cone bipolar cells...
  5. doi request reprint Rod and cone contributions to horizontal cell light responses in the mouse retina
    Jennifer Trümpler
    Department of Neurobiology, Carl von Ossietzky University, D 26111 Oldenburg, Germany
    J Neurosci 28:6818-25. 2008
    ..Our results confirm that rods and cones are coupled by connexin36, and suggest that signal transmission along the axon is unidirectional: signals are passed from horizontal cell soma to axon terminal but not from axon terminal to soma...
  6. doi request reprint Expression and modulation of connexin 30.2, a novel gap junction protein in the mouse retina
    Luis Pérez de Sevilla Müller
    Department of Neurobiology, University of Oldenburg, Oldenburg, Germany
    Vis Neurosci 27:91-101. 2010
    ..Our data provide evidence that coupling of RG A1 cells to displaced amacrine cells is mediated by Cx30.2 and that the extent of this coupling is modulated by protein kinase C...
  7. pmc Ganglion cell adaptability: does the coupling of horizontal cells play a role?
    Karin Dedek
    Department of Neurobiology, University of Oldenburg, Oldenburg, Germany
    PLoS ONE 3:e1714. 2008
    ..This shift is thought to be produced by a change in the ganglion cell receptive field surround, mediated by a decrease in the coupling of horizontal cells...
  8. doi request reprint Expression of Pannexin1 in the outer plexiform layer of the mouse retina and physiological impact of its knockout
    Katharina Kranz
    Department of Neurobiology, University of Oldenburg, D 26111 Oldenburg, Germany
    J Comp Neurol 521:1119-35. 2013
    ..These results suggest that Panx1 channels serve as sinks for extracellular current flow making them possible candidates for the mediation of feedback from horizontal cells to photoreceptors...
  9. doi request reprint Subcellular distribution of connexin45 in OFF bipolar cells of the mouse retina
    Gerrit Hilgen
    Department of Neurobiology, University of Oldenburg, Germany
    J Comp Neurol 519:433-50. 2011
    ....
  10. pmc Cell-specific cre recombinase expression allows selective ablation of glutamate receptors from mouse horizontal cells
    Sebastian Ströh
    Department of Neurobiology, University of Oldenburg, Oldenburg, Germany
    PLoS ONE 8:e83076. 2013
    ..GluA4fl/fl:Cx57+/Cre mice, in which horizontal cells receive less excitatory input, can thus be used to analyze the contribution of horizontal cells to retinal processing. ..
  11. doi request reprint Ablation of retinal horizontal cells from adult mice leads to rod degeneration and remodeling in the outer retina
    Stephan Sonntag
    Life and Medical Sciences Institute, University of Bonn, D 53115 Bonn, Germany
    J Neurosci 32:10713-24. 2012
    ..Thus, the loss of an entire interneuron class can be largely compensated even by the adult retinal network...
  12. doi request reprint Expression and biophysical characterization of voltage-gated sodium channels in axons and growth cones of the regenerating optic nerve
    Andreas Feigenspan
    Institute of Biology, University of Oldenburg, Oldenburg, Germany
    Invest Ophthalmol Vis Sci 51:1789-99. 2010
    ..The purpose of this study was to determine the expression and properties of voltage-gated sodium channels (Na(v)) expressed by regenerating growth cones...
  13. pmc Lack of the sodium-driven chloride bicarbonate exchanger NCBE impairs visual function in the mouse retina
    Gerrit Hilgen
    Department of Neurobiology, University Oldenburg, Oldenburg, Germany
    PLoS ONE 7:e46155. 2012
    ..Consequently, lack of NCBE in the retina may result in changes in pH(i) regulation and chloride-dependent inhibition, leading to altered signal transmission and impaired visual function...
  14. doi request reprint Inputs underlying the ON-OFF light responses of type 2 wide-field amacrine cells in TH::GFP mice
    Gabriel C Knop
    Department of Neurobiology, University of Oldenburg, 26111 Oldenburg, Germany
    J Neurosci 31:4780-91. 2011
    ..Collectively, light responses of type 2 cells were remarkably uniform over a wide range of light intensities. These properties point toward a general function of type 2 cells that is maintained under scotopic and mesopic conditions...
  15. ncbi request reprint Horizontal cell receptive fields are reduced in connexin57-deficient mice
    Jennifer Shelley
    Department of Neurobiology, University of Oldenburg, Oldenburg, Germany
    Eur J Neurosci 23:3176-86. 2006
    ..These data thus provide the first quantification of mouse horizontal cell receptive field size and confirm the unique role of Cx57 in horizontal cell coupling and physiology...
  16. doi request reprint The absence of Complexin 3 and Complexin 4 differentially impacts the ON and OFF pathways in mouse retina
    Immanuel Landgraf
    Department of Biology and Environmental Sciences, Neurobiology, University of Oldenburg, 26111 Oldenburg, Germany
    Eur J Neurosci 36:2470-81. 2012
    ..Most importantly, Cplx 3 is localized in the lobular appendages of AII amacrine cells, the sites of signal transmission from the primary rod pathway into the OFF pathway in the inner plexiform layer...