J Deckert

Summary

Country: Germany

Publications

  1. ncbi request reprint Excess of high activity monoamine oxidase A gene promoter alleles in female patients with panic disorder
    J Deckert
    Department of Psychiatry, University of Wurzburg, Fuchsleinstrasse 15, 97080 Wurzburg, Germany, Istituto di Ricovero e Cura a Carattere Scientifico H San Raffaele, DSNP, Via Prinetti 29, 20127 Milan, Italy
    Hum Mol Genet 8:621-4. 1999
  2. ncbi request reprint Polymorphic MAO-A and 5-HT-transporter genes: analysis of interactions in panic disorder
    P Sand
    Department of Psychiatry, University of Wurzburg, Fuchsleinstr 15, 97080 Wurzburg, Germany
    World J Biol Psychiatry 1:147-50. 2000
  3. ncbi request reprint Systematic mutation screening and association study of the A1 and A2a adenosine receptor genes in panic disorder suggest a contribution of the A2a gene to the development of disease
    J Deckert
    Department of Psychiatry, University of Wurzburg, Germany
    Mol Psychiatry 3:81-5. 1998
  4. ncbi request reprint Human nuclear transcription factor gene CREM: genomic organization, mutation screening, and association analysis in panic disorder
    K Domschke
    Department of Psychiatry, University of Munster, Munster, Germany
    Am J Med Genet B Neuropsychiatr Genet 117:70-8. 2003
  5. doi request reprint Neuropeptide S receptor gene -- converging evidence for a role in panic disorder
    K Domschke
    Department of Psychiatry, University of Muenster, Muenster, Germany
    Mol Psychiatry 16:938-48. 2011
  6. ncbi request reprint Norepinephrine transporter gene (NET) variants in patients with panic disorder
    P G Sand
    Department of Psychiatry, University of Wurzburg, Füchsleinstrazze 15, D 97080, Wurzburg, Germany
    Neurosci Lett 333:41-4. 2002
  7. doi request reprint Sympathetic activity relates to adenosine A(2A) receptor gene variation in blood-injury phobia
    C Hohoff
    Department of Psychiatry, University of Munster, Albert Schweitzer Strasse 11, 48149 Munster, Germany
    J Neural Transm 116:659-62. 2009
  8. ncbi request reprint Exonic variants of the GABA(B) receptor gene and panic disorder
    P G Sand
    Department of Psychiatry, University of Wurzburg, Germany
    Psychiatr Genet 10:191-4. 2000
  9. ncbi request reprint Serotonergic genes modulate amygdala activity in major depression
    U Dannlowski
    Department of Psychiatry, University of Munster, Munster, GermanyIZKF Research Group 4, IZKF Münster, University of Munster, Munster, Germany
    Genes Brain Behav 6:672-6. 2007
  10. ncbi request reprint Rgs 2 gene polymorphisms as modulators of anxiety in humans?
    A Leygraf
    Laboratory of Molecular Psychiatry, Department of Psychiatry, University of Munster, Munster, Germany
    J Neural Transm 113:1921-5. 2006

Collaborators

Detail Information

Publications17

  1. ncbi request reprint Excess of high activity monoamine oxidase A gene promoter alleles in female patients with panic disorder
    J Deckert
    Department of Psychiatry, University of Wurzburg, Fuchsleinstrasse 15, 97080 Wurzburg, Germany, Istituto di Ricovero e Cura a Carattere Scientifico H San Raffaele, DSNP, Via Prinetti 29, 20127 Milan, Italy
    Hum Mol Genet 8:621-4. 1999
    ....
  2. ncbi request reprint Polymorphic MAO-A and 5-HT-transporter genes: analysis of interactions in panic disorder
    P Sand
    Department of Psychiatry, University of Wurzburg, Fuchsleinstr 15, 97080 Wurzburg, Germany
    World J Biol Psychiatry 1:147-50. 2000
    ..There was no significant difference in odds ratios, suggesting that the observed increase of genetic liability by the long MAO-A gene promoter allele is not modified by the 5-HTT gene promoter polymorphism...
  3. ncbi request reprint Systematic mutation screening and association study of the A1 and A2a adenosine receptor genes in panic disorder suggest a contribution of the A2a gene to the development of disease
    J Deckert
    Department of Psychiatry, University of Wurzburg, Germany
    Mol Psychiatry 3:81-5. 1998
    ..Replication studies in independent samples with nuclear families applying the transmission disequilibrium test (TDT) are warranted...
  4. ncbi request reprint Human nuclear transcription factor gene CREM: genomic organization, mutation screening, and association analysis in panic disorder
    K Domschke
    Department of Psychiatry, University of Munster, Munster, Germany
    Am J Med Genet B Neuropsychiatr Genet 117:70-8. 2003
    ..Functional analysis of the observed CREM P 2 promoter polymorphism as well as studies in independent panic disorder samples are necessary...
  5. doi request reprint Neuropeptide S receptor gene -- converging evidence for a role in panic disorder
    K Domschke
    Department of Psychiatry, University of Muenster, Muenster, Germany
    Mol Psychiatry 16:938-48. 2011
    ..The present results provide converging evidence for a female-dominant role of NPSR gene variation in panic disorder potentially through heightened autonomic arousal and distorted processing of anxiety-relevant emotional stimuli...
  6. ncbi request reprint Norepinephrine transporter gene (NET) variants in patients with panic disorder
    P G Sand
    Department of Psychiatry, University of Wurzburg, Füchsleinstrazze 15, D 97080, Wurzburg, Germany
    Neurosci Lett 333:41-4. 2002
    ..Except for a silent substitution (G1287A), overall frequencies of variant alleles were low (< or =0.016). None of the variants under study was found to be associated with PD regardless of an additional diagnosis of agoraphobia...
  7. doi request reprint Sympathetic activity relates to adenosine A(2A) receptor gene variation in blood-injury phobia
    C Hohoff
    Department of Psychiatry, University of Munster, Albert Schweitzer Strasse 11, 48149 Munster, Germany
    J Neural Transm 116:659-62. 2009
    ....
  8. ncbi request reprint Exonic variants of the GABA(B) receptor gene and panic disorder
    P G Sand
    Department of Psychiatry, University of Wurzburg, Germany
    Psychiatr Genet 10:191-4. 2000
    ..There was no indication of an increased vulnerability to panic disorder or agoraphobia with respect to the allelic variants under study...
  9. ncbi request reprint Serotonergic genes modulate amygdala activity in major depression
    U Dannlowski
    Department of Psychiatry, University of Munster, Munster, GermanyIZKF Research Group 4, IZKF Münster, University of Munster, Munster, Germany
    Genes Brain Behav 6:672-6. 2007
    ..Our data suggest that the genetic susceptibility for major depression might be transported via dysfunctional neural activity in brain regions critical for emotion processing...
  10. ncbi request reprint Rgs 2 gene polymorphisms as modulators of anxiety in humans?
    A Leygraf
    Laboratory of Molecular Psychiatry, Department of Psychiatry, University of Munster, Munster, Germany
    J Neural Transm 113:1921-5. 2006
    ..01 and 0.03). This points towards a functional polymorphism at the 3' end of the gene. Our results support the hypothesis that variations of the Rgs2 gene play a role also for the development of anxiety in humans...
  11. ncbi request reprint Loss of human hippocampal adenosine A1 receptors in dementia: evidence for lack of specificity
    J Deckert
    Department of Psychiatry, University of Wurzburg, Germany
    Neurosci Lett 244:1-4. 1998
    ..These results suggest that loss of hippocampal adenosine A1 receptors in dementia is not specific for Alzheimer type pathology...
  12. doi request reprint MAOA and mechanisms of panic disorder revisited: from bench to molecular psychotherapy
    A Reif
    Psychiatric Neurobiology and Bipolar Disorder Program, Department of Psychiatry, Psychosomatics and Psychotherapy, University of Wurzburg, Wurzburg, Germany
    Mol Psychiatry 19:122-8. 2014
    ..These findings might govern how psychotherapy can include genetic information to tailor individualized treatment approaches. ..
  13. doi request reprint Effects of gender and age on serum concentrations of antidepressants under naturalistic conditions
    S Unterecker
    Department of Psychiatry, Psychosomatics and Psychotherapy, University Hospital of Wurzburg, Fuchsleinstrasse 15, 97080, Wurzburg, Germany
    J Neural Transm 120:1237-46. 2013
    ..TDM is recommended to reduce the risk of adverse effects due to supratherapeutic serum levels, also in a naturalistic clinical setting. ..
  14. doi request reprint The effect of age, sex, smoking and co-medication on serum levels of venlafaxine and O-desmethylvenlafaxine under naturalistic conditions
    S Unterecker
    Department of Psychiatry, Psychosomatics and Psychotherapy, University of Wurzburg, Wurzburg, Germany
    Pharmacopsychiatry 45:229-35. 2012
    ..In this study we examined the influence of age, sex, smoking, and co-medication on serum levels of VEN and its metabolite O-desmethylvenlafaxine (ODVEN) in patients treated with VEN under naturalistic conditions...
  15. ncbi request reprint Inhibition of [3H]alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid [AMPA] binding by the anticonvulsant valproate in clinically relevant concentrations: an autoradiographic investigation in human hippocampus
    G Künig
    Clinical Neurochemistry, Department of Psychiatry, University of Wurzburg, Germany
    Epilepsy Res 31:153-7. 1998
    ..Clinically effective brain concentrations for valproate are estimated at 100-200 microM. Our results thus provide evidence that the anticonvulsant effects of valproate may partially be caused by interaction with AMPA receptors...
  16. ncbi request reprint Untangling the human estrogen receptor gene structure
    P Sand
    Department of Psychiatry, University of Wurzburg, Federal Republic of Germany
    J Neural Transm 109:567-83. 2002
    ..We outline additional exons in the genes' 5'- and 3'-untranslated regions, a new polymorphic ER alpha microsatellite and a nested gene which lend themselves to further evolutionary and functional studies...
  17. ncbi request reprint Estrogen receptor 1 gene (ESR1) variants in panic disorder
    P G Sand
    Am J Med Genet 114:426-8. 2002