M Cristina Cardoso

Summary

Affiliation: Darmstadt University of Technology
Country: Germany

Publications

  1. pmc Heterochromatin and gene positioning: inside, outside, any side?
    K Laurence Jost
    Cell Biology and Epigenetics, Department of Biology, Technische Universitat Darmstadt, Schnittspahnstr 10, 64287 Darmstadt, Germany
    Chromosoma 121:555-63. 2012
  2. doi request reprint Structure, function and dynamics of nuclear subcompartments
    M Cristina Cardoso
    Department of Biology, Technische Universitat Darmstadt, Germany
    Curr Opin Cell Biol 24:79-85. 2012
  3. pmc Histone hypoacetylation is required to maintain late replication timing of constitutive heterochromatin
    Corella S Casas-Delucchi
    Department of Biology, Technische Universitat Darmstadt, 64287 Darmstadt, Germany
    Nucleic Acids Res 40:159-69. 2012
  4. pmc Direct homo- and hetero-interactions of MeCP2 and MBD2
    Annette Becker
    Department of Biology, Technische Universitat Darmstadt, Darmstadt, Germany
    PLoS ONE 8:e53730. 2013
  5. pmc 3D-Image analysis platform monitoring relocation of pluripotency genes during reprogramming
    K Laurence Jost
    Department of Biology, Technische Universitat Darmstadt, Darmstadt, Germany
    Nucleic Acids Res 39:e113. 2011
  6. doi request reprint Epigenetic control of DNA replication dynamics in mammals
    Corella S Casas-Delucchi
    Department of Biology, Technische Universitat Darmstadt, Germany
    Nucleus 2:370-82. 2011
  7. pmc Targeted manipulation of heterochromatin rescues MeCP2 Rett mutants and re-establishes higher order chromatin organization
    Corella S Casas-Delucchi
    Department of Biology, Technische Universitat Darmstadt, 64287 Darmstadt, Germany
    Nucleic Acids Res 40:e176. 2012
  8. pmc Histone acetylation controls the inactive X chromosome replication dynamics
    Corella S Casas-Delucchi
    Department of Biology, Technische Universitat Darmstadt, Darmstadt 64287, Germany
    Nat Commun 2:222. 2011
  9. pmc MeCP2 dependent heterochromatin reorganization during neural differentiation of a novel Mecp2-deficient embryonic stem cell reporter line
    Bianca Bertulat
    Department of Biology, Technische Universitat Darmstadt, Darmstadt, Germany
    PLoS ONE 7:e47848. 2012
  10. pmc Generation and characterization of rat and mouse monoclonal antibodies specific for MeCP2 and their use in X-inactivation studies
    K Laurence Jost
    Department of Biology, Technische Universitat Darmstadt, Darmstadt, Germany
    PLoS ONE 6:e26499. 2011

Collaborators

  • Anton Wutz
  • Brian Burke
  • Peter M Carlton
  • Mats G L Gustafsson
  • Thomas Cremer
  • Manel Esteller
  • Lothar Schermelleh
  • Brian Hendrich
  • Corella S Casas-Delucchi
  • K Laurence Jost
  • Bianca Bertulat
  • Annette Becker
  • Heinrich Leonhardt
  • Henry D Herce
  • Andrea Rottach
  • Sebastian Hörner
  • Marius Reinhart
  • Anne Lehmkuhl
  • Sebastian Haase
  • Manuela Milden
  • Jeffrey H Stear
  • Vadim O Chagin
  • Robert M Martin
  • Danny Nowak
  • Elisabeth Kremmer
  • Christian Dietz
  • Patrick Weber
  • Valentina Casa
  • Harald Kolmar
  • Olga Avrutina
  • Robert W Stark
  • Maria Hofstätter
  • Lena Allmann
  • Sebastian Fabritz
  • Simona Scala
  • Janine J Bolius
  • Floriana Della Ragione
  • Joke G van Bemmel
  • Christian Storm
  • Maurizio D'Esposito
  • Daniela Meilinger
  • Maria Luigia De Bonis
  • Juan Sandoval
  • Irina Solovei
  • Daniel Smeets
  • Hanspeter Herzel
  • Hans Peter Rahn
  • Patricia Wolf
  • Marion Cremer
  • Alessandro Brero
  • Jörn M Schmiedel
  • Nadine Schrode
  • Paolo Petazzi
  • Dori Huertas

Detail Information

Publications16

  1. pmc Heterochromatin and gene positioning: inside, outside, any side?
    K Laurence Jost
    Cell Biology and Epigenetics, Department of Biology, Technische Universitat Darmstadt, Schnittspahnstr 10, 64287 Darmstadt, Germany
    Chromosoma 121:555-63. 2012
    ..In this review, we address how (hetero)chromatin structure and proximity might influence gene expression and discuss the challenges and means to unravel this fundamental biological question...
  2. doi request reprint Structure, function and dynamics of nuclear subcompartments
    M Cristina Cardoso
    Department of Biology, Technische Universitat Darmstadt, Germany
    Curr Opin Cell Biol 24:79-85. 2012
    ..Old challenges and new insights are illustrated with examples of DNA replication and nuclear protein dynamics...
  3. pmc Histone hypoacetylation is required to maintain late replication timing of constitutive heterochromatin
    Corella S Casas-Delucchi
    Department of Biology, Technische Universitat Darmstadt, 64287 Darmstadt, Germany
    Nucleic Acids Res 40:159-69. 2012
    ..We speculate that a high histone acetylation level might increase the firing efficiency of origins and, concomitantly, advances the replication timing of distinct genomic regions...
  4. pmc Direct homo- and hetero-interactions of MeCP2 and MBD2
    Annette Becker
    Department of Biology, Technische Universitat Darmstadt, Darmstadt, Germany
    PLoS ONE 8:e53730. 2013
    ..Our results strengthen the possibility that MeCP2 and MBD2 direct interactions could crosslink chromatin fibers and therefore give novel insight into the molecular mechanism of MBD mediated global heterochromatin architecture...
  5. pmc 3D-Image analysis platform monitoring relocation of pluripotency genes during reprogramming
    K Laurence Jost
    Department of Biology, Technische Universitat Darmstadt, Darmstadt, Germany
    Nucleic Acids Res 39:e113. 2011
    ..Thus, our computational approach enables comparative analysis of topological relationships in spite of stark morphological variability typical of biological data sets...
  6. doi request reprint Epigenetic control of DNA replication dynamics in mammals
    Corella S Casas-Delucchi
    Department of Biology, Technische Universitat Darmstadt, Germany
    Nucleus 2:370-82. 2011
    ..Here we present and discuss current knowledge on the con-trol of DNA replication dynamics in mammals and the role of chromatin modifications in this basic biological process...
  7. pmc Targeted manipulation of heterochromatin rescues MeCP2 Rett mutants and re-establishes higher order chromatin organization
    Corella S Casas-Delucchi
    Department of Biology, Technische Universitat Darmstadt, 64287 Darmstadt, Germany
    Nucleic Acids Res 40:e176. 2012
    ..This novel strategy enables specific tethering of any protein to heterochromatin and lays the ground for controlled manipulation of its composition and organization...
  8. pmc Histone acetylation controls the inactive X chromosome replication dynamics
    Corella S Casas-Delucchi
    Department of Biology, Technische Universitat Darmstadt, Darmstadt 64287, Germany
    Nat Commun 2:222. 2011
    ..The epigenetically controlled, highly coordinated replication of the Xi is reminiscent of embryonic genome replication in flies and frogs before genome activation and might be a common feature of transcriptionally silent chromatin...
  9. pmc MeCP2 dependent heterochromatin reorganization during neural differentiation of a novel Mecp2-deficient embryonic stem cell reporter line
    Bianca Bertulat
    Department of Biology, Technische Universitat Darmstadt, Darmstadt, Germany
    PLoS ONE 7:e47848. 2012
    ....
  10. pmc Generation and characterization of rat and mouse monoclonal antibodies specific for MeCP2 and their use in X-inactivation studies
    K Laurence Jost
    Department of Biology, Technische Universitat Darmstadt, Darmstadt, Germany
    PLoS ONE 6:e26499. 2011
    ..The new MeCP2 specific monoclonal antibodies described here perform well in a large variety of immunological applications making them a very valuable set of tools for studies of MeCP2 pathophysiology in situ and in vitro...
  11. doi request reprint Cube-octameric silsesquioxane-mediated cargo peptide delivery into living cancer cells
    Sebastian Hörner
    Clemens Schöpf Institute of Organic Chemistry and Biochemistry, Technische Universitat Darmstadt, Petersenstr 22, 64287 Darmstadt, Germany
    Org Biomol Chem 11:2258-65. 2013
    ..Nuclear targeting was demonstrated in HeLa cells by selective binding of released p21(Cip1/Waf1)-derived cargo peptide to PCNA, a protein involved in DNA replication and repair...
  12. pmc Subdiffraction multicolor imaging of the nuclear periphery with 3D structured illumination microscopy
    Lothar Schermelleh
    Center for Integrated Protein Science, Department of Biology, Ludwig Maximilians University Munich, 82152 Planegg Martinsried, Germany
    Science 320:1332-6. 2008
    ..Multicolor 3D-SIM opens new and facile possibilities to analyze subcellular structures beyond the diffraction limit of the emitted light...
  13. pmc Organization of DNA replication
    Vadim O Chagin
    Department of Biology, Technische Universitat Darmstadt, Germany
    Cold Spring Harb Perspect Biol 2:a000737. 2010
    ..The integration of these data with time lapse microscopy analysis will give us the ability to film and dissect the replication of the genome in situ and in real time...
  14. doi request reprint Generation and characterization of a rat monoclonal antibody specific for multiple red fluorescent proteins
    Andrea Rottach
    Center for Integrated Protein Science Munich, Department of Biology, Ludwig Maximilians University Munich, Planegg Martinsried, Germany
    Hybridoma (Larchmt) 27:337-43. 2008
    ..Applying our versatile antibody, one and the same red fluorescent protein tag can be used to perform not only microscopic studies, but also multiple biochemical assays...
  15. doi request reprint Spatiotemporal visualization of DNA replication dynamics
    Marius Reinhart
    Department of Biology, Technische Universitat Darmstadt, Darmstadt, Germany
    Methods Mol Biol 1042:213-25. 2013
    ....
  16. pmc Chromatin condensation modulates access and binding of nuclear proteins
    Robert M Martin
    Max Delbruck Center for Molecular Medicine, Berlin, Germany
    FASEB J 24:1066-72. 2010
    ..Martin, R. M., Cardoso, M. C. Chromatin condensation modulates access and binding of nuclear proteins...