Johannes F Coy

Summary

Country: Germany

Publications

  1. ncbi request reprint Mutations in the transketolase-like gene TKTL1: clinical implications for neurodegenerative diseases, diabetes and cancer
    Johannes F Coy
    R Biopharm AG, Landwehrstrasse 54, 64293 Darmstadt, Germany
    Clin Lab 51:257-73. 2005
  2. doi request reprint Increased expression of transketolase-like-1 in papillary thyroid carcinomas smaller than 1.5 cm in diameter is associated with lymph-node metastases
    Monica Zerilli
    Department of Human Pathology, University of Palermo, Palermo, Italy
    Cancer 113:936-44. 2008
  3. doi request reprint EDIM-TKTL1 blood test: a noninvasive method to detect upregulated glucose metabolism in patients with malignancies
    Oliver Feyen
    TAVARLIN AG, Landwehrstrasse 54, D 64293 Darmstadt, Germany
    Future Oncol 8:1349-59. 2012
  4. ncbi request reprint Pore membrane and/or filament interacting like protein 1 (POMFIL1) is predominantly expressed in the nervous system and encodes different protein isoforms
    Johannes F Coy
    German Cancer Research Center, Division of Molecular Genomeanalysis, Im Neuenheimer Feld 280, Heidelberg, Germany
    Gene 290:73-94. 2002
  5. ncbi request reprint Expression of the mutated transketolase TKTL1, a molecular marker in gastric cancer
    Wilko I Staiger
    Department of Surgery, University Hospital Mannheim, 68135 Mannheim, Germany
    Oncol Rep 16:657-61. 2006
  6. ncbi request reprint Transketolase protein TKTL1 overexpression: A potential biomarker and therapeutic target in breast cancer
    Martha Földi
    Department of Obstetrics and Gynaecology, University Hospital Freiburg, D 79106 Freiburg, Germany
    Oncol Rep 17:841-5. 2007
  7. doi request reprint Metastasis is promoted by a bioenergetic switch: new targets for progressive renal cell cancer
    Sigrun Langbein
    Department of Urology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Int J Cancer 122:2422-8. 2008

Collaborators

  • Wilko I Staiger
  • Oliver Feyen
  • Sigrun Langbein
  • Monica Zerilli
  • Martha Földi
  • Daniela Cabibi
  • Anna Martorana
  • Marco C Amato
  • Francesco Cappello
  • Vito Rodolico
  • Giancarlo Pompei
  • Carla Giordano
  • Antonio Russo
  • Oliver Kretz
  • Lidija Bau
  • Gerald Gitsch
  • Axel zur Hausen
  • Dirk Watermann
  • Gian Kayser
  • Elmar Stickeler

Detail Information

Publications7

  1. ncbi request reprint Mutations in the transketolase-like gene TKTL1: clinical implications for neurodegenerative diseases, diabetes and cancer
    Johannes F Coy
    R Biopharm AG, Landwehrstrasse 54, 64293 Darmstadt, Germany
    Clin Lab 51:257-73. 2005
    ..We furthermore postulate a novel metabolic concept for the understanding, prevention and therapy of neurodegenerative diseases, diabetes and cancer...
  2. doi request reprint Increased expression of transketolase-like-1 in papillary thyroid carcinomas smaller than 1.5 cm in diameter is associated with lymph-node metastases
    Monica Zerilli
    Department of Human Pathology, University of Palermo, Palermo, Italy
    Cancer 113:936-44. 2008
    ..A mutated transketolase transcript (TKTL1) has been found up-regulated in different human malignancies, and strong TKTL1 protein expression has been associated with aggressiveness and poor patient survival in several epithelial cancers...
  3. doi request reprint EDIM-TKTL1 blood test: a noninvasive method to detect upregulated glucose metabolism in patients with malignancies
    Oliver Feyen
    TAVARLIN AG, Landwehrstrasse 54, D 64293 Darmstadt, Germany
    Future Oncol 8:1349-59. 2012
    ..To determine whether the TKTL1 protein epitope detection in monocytes (EDIM) test allows detection of upregulated glucose metabolism in malignancies...
  4. ncbi request reprint Pore membrane and/or filament interacting like protein 1 (POMFIL1) is predominantly expressed in the nervous system and encodes different protein isoforms
    Johannes F Coy
    German Cancer Research Center, Division of Molecular Genomeanalysis, Im Neuenheimer Feld 280, Heidelberg, Germany
    Gene 290:73-94. 2002
    ....
  5. ncbi request reprint Expression of the mutated transketolase TKTL1, a molecular marker in gastric cancer
    Wilko I Staiger
    Department of Surgery, University Hospital Mannheim, 68135 Mannheim, Germany
    Oncol Rep 16:657-61. 2006
    ..Since molecular targeted inhibition of transketolase enzyme reactions suppresses tumor growth and metastasis, TKTL1 could be a relevant target for anti-transketolase therapies in gastric cancer...
  6. ncbi request reprint Transketolase protein TKTL1 overexpression: A potential biomarker and therapeutic target in breast cancer
    Martha Földi
    Department of Obstetrics and Gynaecology, University Hospital Freiburg, D 79106 Freiburg, Germany
    Oncol Rep 17:841-5. 2007
    ....
  7. doi request reprint Metastasis is promoted by a bioenergetic switch: new targets for progressive renal cell cancer
    Sigrun Langbein
    Department of Urology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Int J Cancer 122:2422-8. 2008
    ..The coexistence of cancer cells with differentially regulated energy supplies provides new insights in carcinogenesis and novel anticancer targets...