H Christiansen

Summary

Country: Germany

Publications

  1. ncbi request reprint Increase of hepcidin plasma and urine levels is associated with acute proctitis and changes in hemoglobin levels in primary radiotherapy for prostate cancer
    Hans Christiansen
    Department of Radiation Oncology, University Hospital Goettingen, Robert Koch Strasse 40, 37099 Goettingen, Germany
    J Cancer Res Clin Oncol 133:297-304. 2007
  2. pmc Gold marker displacement due to needle insertion during HDR-brachytherapy for treatment of prostate cancer: a prospective cone beam computed tomography and kilovoltage on-board imaging (kV-OBI) study
    Markus K A Herrmann
    Department of Radiotherapy, University of Goettingen, Goettingen, Germany
    Radiat Oncol 7:24. 2012
  3. pmc Single fraction radiosurgery using Rapid Arc for treatment of intracranial targets
    Hendrik A Wolff
    Department of Radiotherapy and Radiooncology, Universitatsmedizin Gottingen, Germany
    Radiat Oncol 5:77. 2010
  4. ncbi request reprint External-beam radiotherapy as preparative regimen for hepatocyte transplantation after partial hepatectomy
    Hans Christiansen
    Department of Radiotherapy, University Hospital Goettingen, Goettingen, Germany
    Int J Radiat Oncol Biol Phys 65:509-16. 2006
  5. ncbi request reprint Identification of genes responsive to gamma radiation in rat hepatocytes and rat liver by cDNA array gene expression analysis
    Hans Christiansen
    Department of Radiotherapy, Goettingen University, 37075 Goettingen, Germany
    Radiat Res 165:318-25. 2006
  6. ncbi request reprint x-Irradiation in rat liver: consequent upregulation of hepcidin and downregulation of hemojuvelin and ferroportin-1 gene expression
    Hans Christiansen
    Department of Radiation Oncology, Section of Gastroenterology and Endocrinology, University Hospital Goettingen, Robert Koch Strasse 40, 37075 Goettingen, Germany
    Radiology 242:189-97. 2007
  7. ncbi request reprint Phase I study of continuous mitomycin-C infusion in concomitant radiochemotherapy of primary inoperable advanced head and neck cancer
    Hans Christiansen
    Department of Radiation Oncology, University of Goettingen, Robert Koch Str 40, Goettingen, Germany
    J Cancer Res Clin Oncol 131:815-20. 2005
  8. ncbi request reprint Neck lymph node metastases from an unknown primary tumor retrospective study and review of literature
    Hans Christiansen
    Department of Radiotherapy and Radiooncology, University of Gottingen, Germany
    Strahlenther Onkol 181:355-62. 2005
  9. doi request reprint [Radiotherapy : an option for refractory salivary fistulas]
    H Christiansen
    Klinik und Poliklinik für Strahlentherapie und Radioonkologie, Universitatsmedizin Gottingen, Robert Koch Strasse 40, 37075, Gottingen, Deutschland
    HNO 57:1325-8. 2009
  10. ncbi request reprint Long-term follow-up after transoral laser microsurgery and adjuvant radiotherapy for advanced recurrent squamous cell carcinoma of the head and neck
    Hans Christiansen
    Department of Radiotherapy, University of Gottingen, Gottingen, Germany, and Départmentde Cancérologie, Hopital Morvan, Centre Hospitalier Universitaire de Brest, France
    Int J Radiat Oncol Biol Phys 65:1067-74. 2006

Collaborators

Detail Information

Publications43

  1. ncbi request reprint Increase of hepcidin plasma and urine levels is associated with acute proctitis and changes in hemoglobin levels in primary radiotherapy for prostate cancer
    Hans Christiansen
    Department of Radiation Oncology, University Hospital Goettingen, Robert Koch Strasse 40, 37099 Goettingen, Germany
    J Cancer Res Clin Oncol 133:297-304. 2007
    ..To analyse hepcidin serum and urine levels during radiotherapy for prostate cancer...
  2. pmc Gold marker displacement due to needle insertion during HDR-brachytherapy for treatment of prostate cancer: a prospective cone beam computed tomography and kilovoltage on-board imaging (kV-OBI) study
    Markus K A Herrmann
    Department of Radiotherapy, University of Goettingen, Goettingen, Germany
    Radiat Oncol 7:24. 2012
    ..To evaluate gold marker displacement due to needle insertion during HDR-brachytherapy for therapy of prostate cancer...
  3. pmc Single fraction radiosurgery using Rapid Arc for treatment of intracranial targets
    Hendrik A Wolff
    Department of Radiotherapy and Radiooncology, Universitatsmedizin Gottingen, Germany
    Radiat Oncol 5:77. 2010
    ..This planning study analysed whether Rapid Arc (RA) with stereotactic localisation for single-fraction SRS can solve these problems...
  4. ncbi request reprint External-beam radiotherapy as preparative regimen for hepatocyte transplantation after partial hepatectomy
    Hans Christiansen
    Department of Radiotherapy, University Hospital Goettingen, Goettingen, Germany
    Int J Radiat Oncol Biol Phys 65:509-16. 2006
    ..This study describes a novel selective external-beam irradiation technique as a preparative regimen for hepatocyte transplantation...
  5. ncbi request reprint Identification of genes responsive to gamma radiation in rat hepatocytes and rat liver by cDNA array gene expression analysis
    Hans Christiansen
    Department of Radiotherapy, Goettingen University, 37075 Goettingen, Germany
    Radiat Res 165:318-25. 2006
    ..Thus we identified genes that may be involved in liver steatosis after irradiation. The methods shown in this work should help to further clarify the consequences of radiation exposure in the liver...
  6. ncbi request reprint x-Irradiation in rat liver: consequent upregulation of hepcidin and downregulation of hemojuvelin and ferroportin-1 gene expression
    Hans Christiansen
    Department of Radiation Oncology, Section of Gastroenterology and Endocrinology, University Hospital Goettingen, Robert Koch Strasse 40, 37075 Goettingen, Germany
    Radiology 242:189-97. 2007
    ..To prospectively analyze hepcidin, hemojuvelin, and ferroportin-1 expression after x-irradiation of rat liver and isolated rat hepatocytes...
  7. ncbi request reprint Phase I study of continuous mitomycin-C infusion in concomitant radiochemotherapy of primary inoperable advanced head and neck cancer
    Hans Christiansen
    Department of Radiation Oncology, University of Goettingen, Robert Koch Str 40, Goettingen, Germany
    J Cancer Res Clin Oncol 131:815-20. 2005
    ..A phase I trial to evaluate the maximum tolerated dose (MTD) of continuous mitomycin-C infusion in radiochemotherapy of inoperable HNSCC...
  8. ncbi request reprint Neck lymph node metastases from an unknown primary tumor retrospective study and review of literature
    Hans Christiansen
    Department of Radiotherapy and Radiooncology, University of Gottingen, Germany
    Strahlenther Onkol 181:355-62. 2005
    ..The purpose of this retrospective analysis is to assess the outcome in patients with neck metastases from an unknown primary tumor (CUP). Furthermore, prognostic factors and treatment modalities are discussed...
  9. doi request reprint [Radiotherapy : an option for refractory salivary fistulas]
    H Christiansen
    Klinik und Poliklinik für Strahlentherapie und Radioonkologie, Universitatsmedizin Gottingen, Robert Koch Strasse 40, 37075, Gottingen, Deutschland
    HNO 57:1325-8. 2009
    ..In time, fistula secretion could be inhibited completely. Although the indication for radiotherapy for such fistulas is rare since Botulinum toxin has been in use, it should still be considered in refractory disease courses...
  10. ncbi request reprint Long-term follow-up after transoral laser microsurgery and adjuvant radiotherapy for advanced recurrent squamous cell carcinoma of the head and neck
    Hans Christiansen
    Department of Radiotherapy, University of Gottingen, Gottingen, Germany, and Départmentde Cancérologie, Hopital Morvan, Centre Hospitalier Universitaire de Brest, France
    Int J Radiat Oncol Biol Phys 65:1067-74. 2006
    ..The aim of this study was to evaluate the efficacy of adjuvant radiotherapy after transoral laser microsurgery for advanced recurrent head-and-neck squamous cell carcinoma (HNSCC)...
  11. ncbi request reprint Chemoradioimmunotherapy with 5-fluorouracil, cisplatin and interferon-alpha in pancreatic and periampullary cancer: results of a feasibility study
    M Nitsche
    Department of Radiation Oncology, University of Goettingen, 40, Robert Koch street, 37075 Goettingen, Germany
    Cancer Radiother 12:817-21. 2008
    ..We report the up-to-now experience at our institution...
  12. ncbi request reprint Concurrent low-dose cisplatin and thoracic radiotherapy in patients with inoperable stage III non-small cell lung cancer: a phase II trial with special reference to the hemoglobin level as prognostic parameter
    O Pradier
    Department of Radiotherapy and Radiation Oncology, University of Gottingen, Robert Koch Strasse 40, 37075 Gottingen, Germany
    J Cancer Res Clin Oncol 131:261-9. 2005
    ..The negative impact of anemia on survival has been noticed for other cancer sites including the head and neck, and the uterine cervix, but it has been rarely described in NSCLC cancer patients treated with radiotherapy...
  13. doi request reprint Mediastinal radiotherapy after multidrug chemotherapy and prophylactic cranial irradiation in patients with SCLC--treatment results after long-term follow-up and literature overview
    M K A Herrmann
    Department of Radiotherapy, University Hospital Goettingen, Robert Koch Str 40, 37075 Goettingen, Germany
    Cancer Radiother 15:81-8. 2011
    ..After a long time follow-up, the aim of the study was to evaluate the efficacy and toxicity of sequential chemo-radiotherapy and the effect of prophylactic cranial irradiation (PCI)...
  14. ncbi request reprint Testicular radiation dose after multimodal curative therapy for locally advanced rectal cancer. Influence on hormone levels, quality of life, and sexual functioning
    S Hennies
    Department of Radiotherapy, University Medicine Goettingen, Robert Koch Str 40, 37075 Gottingen, Germany
    Strahlenther Onkol 188:926-32. 2012
    ....
  15. doi request reprint Second primary malignancies in head and neck cancer patients: high prevalence of curable-stage disease
    H A Wolff
    Department of Radiotherapy and Radiooncology, Universitatsmedizin Gottingen, Robert Koch Str 40, 37075, Gottingen, Germany
    Strahlenther Onkol 189:874-80. 2013
    ..Thus, the present study evaluated the potential benefit of CT and other examinations in the detection of SPM in HNSCC patients...
  16. ncbi request reprint Histomorphological tumor regression grading of esophageal carcinoma after neoadjuvant radiochemotherapy: which score to use?
    R M Hermann
    Department of Radiooncology and Radiotherapy, University Hospital, University of Gottingen, Gottingen, Germany
    Dis Esophagus 19:329-34. 2006
    ..After comparing our data with the literature, it is reasonable to consider classifying all patients into 'Complete tumor regression' and 'Incomplete tumor regression'...
  17. doi request reprint Increasing toxicity during neoadjuvant radiochemotherapy as positive prognostic factor for patients with esophageal carcinoma
    S Hennies
    Department of Radiotherapy, University Medicine Goettingen, Gottingen, Germany
    Dis Esophagus 27:146-51. 2014
    ..The hypothesis should be further analyzed on biomolecular and clinical level in future clinical trials. ..
  18. pmc Irradiation leads to apoptosis of Kupffer cells by a Hsp27-dependant pathway followed by release of TNF-alpha
    K Tello
    Department of Internal Medicine, Section of Gastroenterology and Endocrinology, Georg August University Gottingen, Robert Koch Strasse 40, 37075, Gottingen, Germany
    Radiat Environ Biophys 47:389-97. 2008
    ..Furthermore, we suggest that apoptosis of Kupffer cells leads to an increase of TNF-alpha concentration in the culture medium which may be due to cell death rather than active release or synthesis...
  19. doi request reprint HDR brachytherapy: an option for preventing nonmalignant obstruction in patients after lung transplantation
    A Meyer
    Department of Radiation Oncology, Medical School Hannover, Carl Neuberg Str 1, 30625, Hannover, Germany
    Strahlenther Onkol 188:1085-90. 2012
    ..Interventional bronchoscopy is the main treatment modality in managing benign airway obstructions following lung transplantation. We analyzed the effect of intraluminal brachytherapy on preventing recurrence of hyperplastic tissue...
  20. ncbi request reprint Presence of human papillomavirus-18 and Epstein-Barr virus in a squamous cell carcinoma of the tongue in a 20-year-old patient. Case report and review of the current literature
    R M Hermann
    Department of Radiotherapy, Georg August Universitat, Gottingen, Germany
    Cancer Radiother 8:262-5. 2004
    ..To our knowledge, this is the first case of co-infection in carcinoma of the tongue to be reported. We review the present data and theories concerning viral oncogenesis of oral carcinomas...
  21. doi request reprint Regional transient portal ischemia and irradiation as preparative regimen for hepatocyte transplantation
    S Koenig
    Department of General and Visceral Surgery, University Medical Centre Goettingen, Goettingen, Germany
    Cell Transplant 20:303-11. 2011
    ..The method described clearly has potential for clinical application...
  22. ncbi request reprint Developmental expression of the pluripotency factor sal-like protein 4 in the monkey, human and mouse testis: restriction to premeiotic germ cells
    K Eildermann
    Stem Cell Biology Unit, German Primate Center Leibniz Institute for Primate Research, Gottingen, Germany
    Cells Tissues Organs 196:206-20. 2012
    ....
  23. doi request reprint Craniospinal irradiation with concurrent temozolomide and nimotuzumab in a child with primary metastatic diffuse intrinsic pontine glioma. A compassionate use treatment
    K Muller
    Department of Radiation Oncology, University Medical Center Leipzig, Stephan Str 9a, 04103, Leipzig, Germany
    Strahlenther Onkol 189:693-6. 2013
    ..The disease could be stabilized for a few months. A routine MRI scan finally depicted disease progression 5.7 months after the start of irradiation. The patient died 1.9 months later. ..
  24. ncbi request reprint Effect of keratinocyte growth factor on the proliferation, clonogenic capacity and colony size of human epithelial tumour cells in vitro
    A Hille
    Klinik fur Strahlentherapie und Radioonkologie, Georg August Universitat Gottingen, Robert Koch Str 40, D 37075 Gottingen, Germany
    Int J Radiat Biol 79:119-28. 2003
    ..The effect of recombinant human keratinocyte growth factor (rHuKGF) on the proliferation, clonogenic capacity and colony size of low-passage human epithelial tumour cells was tested in vitro...
  25. ncbi request reprint A long-term follow-up study after split-course irradiation with concurrent chemotherapy (carboplatin) for locally advanced head and neck cancer and a review of the literature
    Olivier Pradier
    Department of Radiotherapy, University of Gottingen, Gottingen, Germany
    ORL J Otorhinolaryngol Relat Spec 66:325-31. 2004
    ..The purpose of this study was to evaluate the efficacy and toxicity of split-course radiotherapy combined with concurrent carboplatin chemotherapy after long-term follow-up...
  26. ncbi request reprint A prospective study of faecal calprotectin and lactoferrin in the monitoring of acute radiation proctitis in prostate cancer treatment
    Andrea Hille
    Department of Radiotherapy and Radio Oncology, University of Gottingen, Gottingen, Germany
    Scand J Gastroenterol 43:52-8. 2008
    ..Acute radiation proctitis is a relevant complication of pelvic radiation. The purpose of this study was to investigate two markers of gut inflammation as non-invasive diagnostic tools to evaluate acute radiation proctitis...
  27. pmc In vitro studies on the modification of low-dose hyper-radiosensitivity in prostate cancer cells by incubation with genistein and estradiol
    Robert Michael Hermann
    Department of Radiotherapy and Radiooncology, University Hospital Goettingen, Robert Koch Str, 40, 37075, Goettingen, Germany
    Radiat Oncol 3:19. 2008
    ..As the majority of prostate cancers (PC) express estrogen receptors, we evaluated the combination of radiation and estrogenic stimulation (estrogen and genistein) on the radiosensitivity of PC cells in vitro...
  28. ncbi request reprint Concomitant radiochemotherapy in primary inoperable advanced head and neck cancer with 5-fluorouracil and mitomycin-C
    Hans Christiansen
    Department of Radiation Oncology, Robert Koch Str 40, 37075 Goettingen, Germany
    Head Neck 26:845-53. 2004
    ..The purpose of this study was to evaluate the efficacy and toxicity of radiotherapy and concomitant 5-fluorouracil (5-FU) and mitomycin-C infusion in inoperable head and neck cancer...
  29. ncbi request reprint Effect of pentoxifylline and tocopherol on radiation proctitis/enteritis
    Andrea Hille
    Department of Radiotherapy and Radiation Oncology, University of Goettingen, Germany
    Strahlenther Onkol 181:606-14. 2005
    ..In a retrospective analysis the clinical benefit of the treatment with pentoxifylline/tocopherol on radiation-induced proctitis/enteritis was evaluated, compared to supportive care only...
  30. ncbi request reprint A phase III randomized, placebo-controlled, double-blind study of misoprostol rectal suppositories to prevent acute radiation proctitis in patients with prostate cancer
    Andrea Hille
    Department of Radiotherapy and Radiooncology, University of Goettingen, Goettingen, Germany
    Int J Radiat Oncol Biol Phys 63:1488-93. 2005
    ....
  31. ncbi request reprint Comparison of the combined action of oxaliplatin or cisplatin and radiation in cervical and lung cancer cells
    Margret Rave-Frank
    Georg August Universität Göttingen Bereich Humanmedizin, Klinik fur Strahlentherapie und Radioonkologie, Gottingen, Germany
    Int J Radiat Biol 83:41-7. 2007
    ..To test the combined effects of oxaliplatin and radiation versus cisplatin and radiation using human cervical and lung cancer cell lines...
  32. doi request reprint Irradiation as preparative regimen for hepatocyte transplantation causes prolonged cell cycle block
    Sarah Koenig
    University Hospital Goettingen, Department of General and Visceral Surgery, Robert Koch Strasse 40, 37099 Goettingen, Germany
    Int J Radiat Biol 84:285-98. 2008
    ..We investigated the changes in the liver induced by IR explaining the loss of reproductive integrity in endogenous hepatocytes...
  33. ncbi request reprint Transoral laser microsurgery for advanced laryngeal cancer
    Michael L Hinni
    Department of Otolaryngology, Head and Neck Surgery, Mayo Clinic Arizona, Phoenix, AZ 85054, USA
    Arch Otolaryngol Head Neck Surg 133:1198-204. 2007
    ..To report the oncologic and functional outcomes of transoral laser microsurgery (TLM) in the treatment of advanced laryngeal cancer...
  34. ncbi request reprint Organ preserving transoral laser microsurgery for cancer of the hypopharynx
    Alexios Martin
    Department of Otorhinolaryngology Head and Neck Surgery, University of Gottingen, Gottingen, Germany
    Laryngoscope 118:398-402. 2008
    ..To assess the feasibility of transoral laser microsurgery (TLM) in the treatment of hypopharyngeal cancer, with a special focus on piriform sinus carcinomas, and to report the oncologic and functional outcomes...
  35. doi request reprint Effect of radiation on gene expression of rat liver chemokines: in vivo and in vitro studies
    Federico Moriconi
    Department of Gastroenterology and Endocrinology, Gottingen University, 37075 Goettingen, Germany
    Radiat Res 169:162-9. 2008
    ..The reason for the lack of liver inflammation in this model has still to be clarified...
  36. ncbi request reprint Irradiation leads to susceptibility of hepatocytes to TNF-alpha mediated apoptosis
    Hans Christiansen
    Department of Radiation Oncology, University of Goettingen, Robert Koch Str 40, 37075 Goettingen, Germany
    Radiother Oncol 72:291-6. 2004
    ..The pathogenesis of radiation-induced-liver-disease (RILD) is still unknown. We tested the hypothesis that irradiated liver macrophages influence the viability of radiation stressed hepatocytes...
  37. ncbi request reprint Value of postoperative radiotherapy in patients with pathologic N1 neck disease
    Martin C Jäckel
    Department of Otorhinolaryngology, University Hospital of Essen, Essen, Germany
    Head Neck 30:875-82. 2008
    ..The aim of this study was to assess the efficacy of postoperative radiotherapy for the treatment of patients with pathologic N1 neck disease...
  38. ncbi request reprint Adjuvant radiotherapy after transoral laser microsurgery for advanced squamous carcinoma of the head and neck
    Olivier Pradier
    Department of Radiotherapy, University of Gottingen, Gottingen, Germany
    Int J Radiat Oncol Biol Phys 63:1368-77. 2005
    ....
  39. ncbi request reprint Letter to the editor concerning Senan et al., [Radiother Oncol 2004;71:139-146]
    Elisabeth Weiss
    Radiother Oncol 74:346-7. 2005
  40. ncbi request reprint Rationale for individualized therapy in Sinonasal Teratocarcinosarcoma (SNTC): case report
    Mirko Nitsche
    Department of Radiotherapy, University of Gottingen, Germany
    Onkologie 28:653-6. 2005
    ..We present the first case of malignant SNTC treated with individualized multimodal therapy including a histology-specific chemotherapy...
  41. ncbi request reprint Paraganglioma of the cerebellum: case report and review of the literature
    Mirko Nitsche
    Klinik und Poliklinik für Strahlentherapie und Radioonkologie, Georg August Universitat, Robert Koch Strasse 40, 37075 Goettingen, Germany
    Int J Clin Oncol 10:447-52. 2005
    ..The optimal therapeutic strategy with regard to the benefit of adjuvant radiotherapy after total or subtotal resection has yet to be defined...
  42. doi request reprint The combined effect of fludarabine monophosphate and radiation as well as gemcitabine and radiation on squamous carcinoma tumor cell lines in vitro
    Mirko Nitsche
    Department of Radiation Oncology, Georg August Universitat Gottingen, Gottingen
    Int J Radiat Biol 84:643-57. 2008
    ..This investigation focuses on the combined effect of either fludarabine or gemcitabine and radiation on human squamous carcinoma cell lines in vitro, providing data for future decisions on head and neck chemoradiotherapy regimen...
  43. ncbi request reprint A special device (double-hole belly board) and optimal radiation technique to reduce testicular radiation exposure in radiotherapy of rectal cancer
    Hilke Vorwerk
    Department of Radiation Oncology, University Hospital Gottingen, Gottingen, Germany
    Radiother Oncol 84:320-7. 2007
    ..We developed a double-hole belly board (DHBB) and evaluated its potential to reduce testicular dose...