Yong Chen

Summary

Country: Germany

Publications

  1. pmc 5-hydroxyindolacetic acid (5-HIAA), a main metabolite of serotonin, is responsible for complete Freund's adjuvant-induced thermal hyperalgesia in mice
    Yong Chen
    Department of Neurology, University of Wurzburg, Josef Schneider Strasse 11, Wurzburg 97080, Germany
    Mol Pain 7:21. 2011
  2. pmc Nitric oxide synthase modulates CFA-induced thermal hyperalgesia through cytokine regulation in mice
    Yong Chen
    Department of Neurology, University of Wurzburg, Josef Schneider Str 11, 97080 Wurzburg, Germany
    Mol Pain 6:13. 2010
  3. ncbi request reprint Activation of the nociceptin opioid system in rat sensory neurons produces antinociceptive effects in inflammatory pain: involvement of inflammatory mediators
    Yong Chen
    Department of Neurology, University of Wurzburg, Wurzburg, Germany
    J Neurosci Res 85:1478-88. 2007
  4. ncbi request reprint Nociceptin and its receptor in rat dorsal root ganglion neurons in neuropathic and inflammatory pain models: implications on pain processing
    Yong Chen
    Department of Neurology, Julius Maximilians University, Wurzburg, Germany
    J Peripher Nerv Syst 11:232-40. 2006
  5. ncbi request reprint Differences in inflammatory pain in nNOS-, iNOS- and eNOS-deficient mice
    Michael Karl Boettger
    Department of Neurology, Julius Maximilians University, Josef Schneider Str 11, 97080, Wurzburg, Germany
    Eur J Pain 11:810-8. 2007
  6. doi request reprint Reduced thermal hyperalgesia and enhanced peripheral nerve injury after hind paw inflammation in mice lacking the serotonin-transporter
    Florian Palm
    Department of Neurology, University of Wurzburg, Neurologische Klinik der Universit├Ąt, D 97080 Wurzburg, Germany
    Eur J Pain 12:790-7. 2008
  7. doi request reprint Activation of TRPV1 contributes to morphine tolerance: involvement of the mitogen-activated protein kinase signaling pathway
    Yong Chen
    Department of Neurology, University of Wurzburg, 97080 Wurzburg, Germany
    J Neurosci 28:5836-45. 2008
  8. ncbi request reprint Possible mechanism of referred pain in the perineum and pelvis associated with the prostate in rats
    Yong Chen
    Department of Urology, Southwest Hospital, Third Military Medical University, Chongqing, China 40008
    J Urol 174:2405-8. 2005
  9. doi request reprint Differential ConA-enriched urinary proteome in rat experimental glomerular diseases
    Yan Wang
    Department of Physiology and Pathophysiology, School of Basic Medicine Peking Union Medical College, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, 5 Dongdan Santiao, Beijing 100005, China
    Biochem Biophys Res Commun 371:385-90. 2008
  10. ncbi request reprint Laparoscopy-assisted creation of a liver failure model in pigs
    Takeshi Yuasa
    Department of Gastroenterological Surgery, Transplant, and Surgical Oncology, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan
    Cell Transplant 17:187-93. 2008

Collaborators

  • Claudia Sommer
  • Klaus Peter Lesch
  • Manfred Gerlach
  • Andreas Reif
  • Nurcan Uceyler
  • A Schmitt
  • Christian Geis
  • Peter Riederer
  • Rainald Mossner
  • Congying Wang
  • Chao Ma
  • Fletcher White
  • Lan He
  • Michael K Boettger
  • Li xiang Chen
  • Rui Wang
  • Florian Palm
  • Bawarjan Schatlo
  • Takeshi Yuasa
  • Yan Wang
  • Hirofumi Noguchi
  • Naoya Kobayashi
  • Chuan Jun Wei
  • Tao Bo
  • Shinichi Matsumoto
  • Noriaki Tanaka
  • Qi Yang
  • Kachi Illoh
  • Jorge David Rivas-Carrillo
  • Johann Gross
  • Zhuan Zi Wang
  • Quan Fang
  • Yong He
  • Fan Zhang
  • Marcus W Parker
  • Sucan Ma
  • Siqi Hu
  • Tsuyoshi Yamamoto
  • Naomi Lewin
  • Youhe Gao
  • Stefan Bischofs
  • Shuzhen Wu
  • Chen Shao
  • Erica C Henning
  • Mingxi Li
  • Alejandro Soto-Guiterrez
  • Marsha J Merrill
  • Lawrence L Latour
  • Ryszard M Pluta
  • Ling Zhang
  • Yang Zhang
  • Jorge D Rivas-Carrillo
  • Edward H Oldfield
  • Nahal Golpayegani
  • Nali Navarro-Alvarez
  • Xiao hua Zhu
  • Qing Le Zeng
  • Jiang yun Wang
  • Yan Hao Li
  • Que Lin Mei
  • Ding An Mao
  • Yan fang Li
  • Jian bo Zhao
  • Yasuhiko Tabata
  • Alejandro Soto-Gutierrez
  • John Diehl
  • Caiyun Fu
  • Haruo Misawa
  • Min Chang
  • Yali Peng
  • Nalu Navarro-Alvarez
  • Orieji Illoh
  • John Hallenbeck
  • Catherine Campbell
  • Abdel Elkhaloun
  • Teru Okitsu
  • James Cherry
  • Kurt Andersson
  • Nadejda Andreeva
  • Iris Muller
  • Mario Herrera-Marschitz
  • Jia Guo
  • Qiang Chen
  • Ke Feng Dou
  • Jun Zhou
  • Hua Wu
  • John M Hallenbeck
  • Chang Sup Kim
  • Dae Hyuk Kweon
  • Byron D Ford

Detail Information

Publications26

  1. pmc 5-hydroxyindolacetic acid (5-HIAA), a main metabolite of serotonin, is responsible for complete Freund's adjuvant-induced thermal hyperalgesia in mice
    Yong Chen
    Department of Neurology, University of Wurzburg, Josef Schneider Strasse 11, Wurzburg 97080, Germany
    Mol Pain 7:21. 2011
    ..Previous work led to the hypothesis that 5-hydroxyindolacetic acid (5-HIAA), a main metabolite of serotonin, might by itself influence pain thresholds...
  2. pmc Nitric oxide synthase modulates CFA-induced thermal hyperalgesia through cytokine regulation in mice
    Yong Chen
    Department of Neurology, University of Wurzburg, Josef Schneider Str 11, 97080 Wurzburg, Germany
    Mol Pain 6:13. 2010
    ..Here we asked whether cytokines, which have well-described roles in inflammatory pain, are downstream targets of NO in inflammatory pain and which of the isoforms of NOS are involved in this process...
  3. ncbi request reprint Activation of the nociceptin opioid system in rat sensory neurons produces antinociceptive effects in inflammatory pain: involvement of inflammatory mediators
    Yong Chen
    Department of Neurology, University of Wurzburg, Wurzburg, Germany
    J Neurosci Res 85:1478-88. 2007
    ..Together, these findings reveal novel mechanisms by which the NC system produces analgesia...
  4. ncbi request reprint Nociceptin and its receptor in rat dorsal root ganglion neurons in neuropathic and inflammatory pain models: implications on pain processing
    Yong Chen
    Department of Neurology, Julius Maximilians University, Wurzburg, Germany
    J Peripher Nerv Syst 11:232-40. 2006
    ..Thus, NC and the ORL1 receptor may be involved in the modulation of neuropathic and inflammatory pain at the level of the primary afferent neuron...
  5. ncbi request reprint Differences in inflammatory pain in nNOS-, iNOS- and eNOS-deficient mice
    Michael Karl Boettger
    Department of Neurology, Julius Maximilians University, Josef Schneider Str 11, 97080, Wurzburg, Germany
    Eur J Pain 11:810-8. 2007
    ..These results support the proposed role of nNOS in sensitization of DRG neurones, and might indicate that CGRP is involved in this process...
  6. doi request reprint Reduced thermal hyperalgesia and enhanced peripheral nerve injury after hind paw inflammation in mice lacking the serotonin-transporter
    Florian Palm
    Department of Neurology, University of Wurzburg, Neurologische Klinik der Universit├Ąt, D 97080 Wurzburg, Germany
    Eur J Pain 12:790-7. 2008
    ..Human variants of the 5-HTT genotypes might be part of the factors determining the extent of nerve injury and hyperalgesia in inflammation...
  7. doi request reprint Activation of TRPV1 contributes to morphine tolerance: involvement of the mitogen-activated protein kinase signaling pathway
    Yong Chen
    Department of Neurology, University of Wurzburg, 97080 Wurzburg, Germany
    J Neurosci 28:5836-45. 2008
    ..Thus, blocking TRPV1 might be a way to reduce morphine tolerance...
  8. ncbi request reprint Possible mechanism of referred pain in the perineum and pelvis associated with the prostate in rats
    Yong Chen
    Department of Urology, Southwest Hospital, Third Military Medical University, Chongqing, China 40008
    J Urol 174:2405-8. 2005
    ..Since persistent pain in the perineum and pelvic floor associated with chronic prostatitis /chronic pelvic pain syndrome has been hypothesized to be referred pain, it might also be explained by neural mechanisms...
  9. doi request reprint Differential ConA-enriched urinary proteome in rat experimental glomerular diseases
    Yan Wang
    Department of Physiology and Pathophysiology, School of Basic Medicine Peking Union Medical College, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, 5 Dongdan Santiao, Beijing 100005, China
    Biochem Biophys Res Commun 371:385-90. 2008
    ..1 glomerulonephritis, respectively...
  10. ncbi request reprint Laparoscopy-assisted creation of a liver failure model in pigs
    Takeshi Yuasa
    Department of Gastroenterological Surgery, Transplant, and Surgical Oncology, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan
    Cell Transplant 17:187-93. 2008
    ..We believe that our model is the first report on creation of a reliable model for liver failure in pigs to assess the efficacy of liver-targeted cell therapies...
  11. ncbi request reprint Isobolographic analysis of the analgesic interactions between ketamine and tramadol
    Yong Chen
    Department of Pharmacy, National University of Singapore, Singapore
    J Pharm Pharmacol 54:623-31. 2002
    ..However, the coadministration produced synergistic antinociception in the chemical-induced persistent pain model...
  12. ncbi request reprint Nitrite does not provide additional protection to thrombolysis in a rat model of stroke with delayed reperfusion
    Bawarjan Schatlo
    Surgical Neurology Branch, National Institutes of Neurological Disorders and Stroke, NIH, Bethesda, MD 20892, USA
    J Cereb Blood Flow Metab 28:482-9. 2008
    ..These results suggest that nitrite is not a protective adjuvant therapy to delayed rtPA administration after ischemic stroke in rats...
  13. ncbi request reprint [Percutaneous intradiscal oxygen-ozone injection for lumbar disc herniation: no need of perioperative antibiotic prophylaxis]
    Chuan Jun Wei
    Department of Interventional Radiology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China wcjun1999 163 com
    Nan Fang Yi Ke Da Xue Xue Bao 27:384-6. 2007
    ..To evaluate the feasibility of no antibiotic administration to prevent infection during the perioperative period of percutaneous intradiscal ozone-injection for treatment of lumbar disc herniation...
  14. ncbi request reprint [Long-term effects of recurrent seizures in neonate period on gamma-aminobutyric acid A receptor alpha1 and beta2 subunits expression in adult brain: experiment with rats]
    Tao Bo
    Department of Pediatrics, Second Xiangya Hospital, Central Southern Universality, Changsha 410011, China
    Zhonghua Yi Xue Za Zhi 87:275-8. 2007
    ..To investigate the long-term effects of recurrent seizures in neonate period on the expression of gamma-aminobutyric acid A receptor (GABAAR) alpha1 and beta2 subunits in brain and spatial memory and seizure susceptibility in adult period...
  15. ncbi request reprint Similar electrophysiological changes in axotomized and neighboring intact dorsal root ganglion neurons
    Chao Ma
    Department of Anesthesiology, Yale University School of Medicine, New Haven, Connecticut 06510, USA
    J Neurophysiol 89:1588-602. 2003
    ....
  16. ncbi request reprint Effects of nociceptin (13-17) in pain modulation at supraspinal level in mice
    Li xiang Chen
    Department of Biochemistry and Molecular Biology, School of Life Science, Lanzhou University, 298 Tian Shui Road, 730000, Peoples Republic of, Lanzhou, China
    Neurosci Lett 331:95-8. 2002
    ....
  17. ncbi request reprint Amelioration of diabetes in mice after single-donor islet transplantation using the controlled release of gelatinized FGF-2
    Jorge David Rivas-Carrillo
    Department of Surgery, Okayama University Graduate School of Medicine and Dentistry, Okayama 700 8558, Japan
    Cell Transplant 15:939-44. 2006
    ..In contrast, the transplantation of islets without FGF-2 supplementation showed poor revascularization and failed to control the blood glucose levels in the diabetic mice...
  18. ncbi request reprint Overexpression of monocyte chemoattractant protein 1 in the brain exacerbates ischemic brain injury and is associated with recruitment of inflammatory cells
    Yong Chen
    Stroke Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892 4128, USA
    J Cereb Blood Flow Metab 23:748-55. 2003
    ..These results indicate that MCP-1 can contribute to inflammatory injury in stroke...
  19. ncbi request reprint A rat model for acute hepatic failure
    Yong He
    Department of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi an 710032, China
    Hepatobiliary Pancreat Dis Int 2:423-5. 2003
    ..To develop a surgical model of acute hepatic failure...
  20. ncbi request reprint Study in vitro and in vivo of nociceptin/orphanin FQ(1-13)NH2 analogues substituting N-Me-Gly for Gly2 or Gly3
    Li xiang Chen
    Department of Biochemistry and Molecular Biology, School of Life Science, Lanzhou University, 222 Tian Shui South Road, Lanzhou 730000, PR China
    Peptides 25:1349-54. 2004
    ..The present work also helps to provide a novel method to elucidate structural and conformational requirements of the opioid peptide-receptor interaction...
  21. ncbi request reprint Effect of perinatal asphyxia on tyrosine hydroxylase and D2 and D1 dopamine receptor mRNA levels expressed during early postnatal development in rat brain
    Johann Gross
    Department of Otorhinolaryngology, Charite Hospital, Humboldt University, Spandauer Damm 130, Haus 31, 14050 Berlin, Germany
    Brain Res Mol Brain Res 134:275-81. 2005
    ..These changes may affect differently dopamine D2R and D1R expression along development, contributing to long-term neurocircuitry imbalances...
  22. ncbi request reprint Mechanisms underlying enhanced P2X receptor-mediated responses in the neuropathic pain state
    Yong Chen
    Department of Neuroscience and Cell Biology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555 1069, USA
    Pain 119:38-48. 2005
    ..Thus, the enhancement of trafficking of P2X3 receptors is likely an important mechanism contributing to the increase in receptor function after nerve injury...
  23. ncbi request reprint Effects of [Nphe1]nociceptin(1-13)NH2, [Phe1(CH2-NH)Gly2]nociceptin(1- 13)NH2, and nocistatin on nociceptin inhibited constrictions of guinea pig isolated bronchus
    Qi Yang
    Department of Biochemistry and Molecular Biology, School of Life Science, Lanzhou University, 222 Tian Shui South Road, Lanzhou 730000, People s Republic of China
    Protein Pept Lett 13:185-8. 2006
    ..The results demonstrate that [Nphe1]NC(1-13)NH2 and [F/G]NC(1- 13)NH2 but not NST act as selective antagonists of the NC receptor and the effects of NC on EFS-induced constrictions of guinea pig isolated bronchus...
  24. pmc Mucosal tolerance to E-selectin and response to systemic inflammation
    Kachi Illoh
    Department of Neurology, University of Texas Health Sciences Center, Houston, Texas 77030, USA
    J Cereb Blood Flow Metab 26:1538-50. 2006
    ..These changes, while giving an insight to the underlying mechanisms, serve as possible targets for future studies to facilitate translation to human clinical trials...
  25. ncbi request reprint Neuregulin expression after focal stroke in the rat
    Marcus W Parker
    Johns Hopkins School of Medicine, Baltimore, MD, USA
    Neurosci Lett 334:169-72. 2002
    ..There was no neuregulin co-localization with astrocytes or macrophages. These results demonstrate that neuregulin is induced in neurons following ischemic stroke and may be involved in neuroprotection and repair...
  26. ncbi request reprint The four-helix bundle of the neuronal target membrane SNARE complex is neither disordered in the middle nor uncoiled at the C-terminal region
    Fan Zhang
    Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, Iowa 50011, USA
    J Biol Chem 277:24294-8. 2002
    ..It also provides possible structural-functional clues to the membrane fusion in the v-SNARE deleted fusion models...