M Hanefeld

Summary

Affiliation: Centre for Clinical Studies
Country: Germany

Publications

  1. ncbi request reprint [Screening, prevention and early therapy of type 2 diabetics]
    M Hanefeld
    Zentrum für Klinische Studien, Forschungsbereich Stoffwechsel und Endokrinologie, Dresden
    MMW Fortschr Med 146:28-9, 31. 2004
  2. doi request reprint [Glycemic control and cardiovascular benefit: What do we know today?]
    M Hanefeld
    Zentrum für Klinische Studien, GWT TUD GmbH, Dresden
    Dtsch Med Wochenschr 135:301-7. 2010
  3. ncbi request reprint The effects of orlistat on body weight and glycaemic control in overweight patients with type 2 diabetes: a randomized, placebo-controlled trial
    M Hanefeld
    Zentrum für Klinische Studien, GWT Technische Universität Dresden, Dresden, Germany
    Diabetes Obes Metab 4:415-23. 2002
  4. pmc Effects of insulin glargine versus metformin on glycemic variability, microvascular and beta-cell function in early type 2 diabetes
    F Pistrosch
    Study Centre Prof Hanefeld, GWT, Technical University Dresden, Dresden, Germany
    Acta Diabetol 50:587-95. 2013
  5. doi request reprint Effects of the alpha glucosidase inhibitor acarbose on endothelial function after a mixed meal in newly diagnosed type 2 diabetes
    F Pistrosch
    Department of Medicine, Technical University of Dresden, Dresden, Germany
    Horm Metab Res 41:104-8. 2009
  6. ncbi request reprint Effect of targeting normal fasting glucose levels with basal insulin glargine on glycaemic variability and risk of hypoglycaemia: a randomized, controlled study in patients with early Type 2 diabetes
    M Hanefeld
    GWT TUD GmbH, Center for Clinical Studies, Dresden, Germany
    Diabet Med 27:175-80. 2010
  7. doi request reprint Effect of acarbose on postmeal mononuclear blood cell response in patients with early type 2 diabetes: the AI(I)DA study
    M Hanefeld
    Center for Clinical Studies, GWT Dresden, Dresden, Germany
    Horm Metab Res 41:132-6. 2009
  8. ncbi request reprint Relationship between diurnal glucose levels and HbA1c in type 2 diabetes
    F Pistrosch
    Nephrology, Dept of Medicine, University Hospital, Dresden, Germany
    Horm Metab Res 38:455-9. 2006
  9. doi request reprint Polymorphisms in perilipin gene (PLIN) are not associated with obesity and weight variation in people with high risk of type 2 diabetes
    A Bergmann
    Health Care Centre of Medical Faculty Carl Gustav Carus of the Technical University Dresden, Dresden, Germany
    Exp Clin Endocrinol Diabetes 116:S56-8. 2008
  10. ncbi request reprint Glycemic control and treatment failure with pioglitazone versus glibenclamide in type 2 diabetes mellitus: a 42-month, open-label, observational, primary care study
    M Hanefeld
    Centre for Clinical Studies, GWT Technical University, Dresden, Germany
    Curr Med Res Opin 22:1211-5. 2006

Detail Information

Publications58

  1. ncbi request reprint [Screening, prevention and early therapy of type 2 diabetics]
    M Hanefeld
    Zentrum für Klinische Studien, Forschungsbereich Stoffwechsel und Endokrinologie, Dresden
    MMW Fortschr Med 146:28-9, 31. 2004
    ..The observation that statins, ACE inhibitors and AT1 blockers also contributed to a reduction of new diabetes cases was made in studies on the prevention of coronary heart diseases...
  2. doi request reprint [Glycemic control and cardiovascular benefit: What do we know today?]
    M Hanefeld
    Zentrum für Klinische Studien, GWT TUD GmbH, Dresden
    Dtsch Med Wochenschr 135:301-7. 2010
    ..This, in turn, requires a growing body of evidence from large, long-term outcome trials - but appropriate data are still unavailable for the vast majority of antidiabetic drugs...
  3. ncbi request reprint The effects of orlistat on body weight and glycaemic control in overweight patients with type 2 diabetes: a randomized, placebo-controlled trial
    M Hanefeld
    Zentrum für Klinische Studien, GWT Technische Universität Dresden, Dresden, Germany
    Diabetes Obes Metab 4:415-23. 2002
    ..To assess the long-term effects of orlistat on body weight, glycaemic control and cardiovascular risk factors in overweight patients with type 2 diabetes...
  4. pmc Effects of insulin glargine versus metformin on glycemic variability, microvascular and beta-cell function in early type 2 diabetes
    F Pistrosch
    Study Centre Prof Hanefeld, GWT, Technical University Dresden, Dresden, Germany
    Acta Diabetol 50:587-95. 2013
    ..MET treatment resulted in an improvement of microvascular function. Studies of longer duration are needed to evaluate the durability of glucose control and β cell protection with early GLA treatment...
  5. doi request reprint Effects of the alpha glucosidase inhibitor acarbose on endothelial function after a mixed meal in newly diagnosed type 2 diabetes
    F Pistrosch
    Department of Medicine, Technical University of Dresden, Dresden, Germany
    Horm Metab Res 41:104-8. 2009
    ..Early type 2 diabetes is a state of both fasting and postprandial ED, which is not sensitive to acarbose treatment. Protective cardiovascular effects of acarbose might involve other mechanisms...
  6. ncbi request reprint Effect of targeting normal fasting glucose levels with basal insulin glargine on glycaemic variability and risk of hypoglycaemia: a randomized, controlled study in patients with early Type 2 diabetes
    M Hanefeld
    GWT TUD GmbH, Center for Clinical Studies, Dresden, Germany
    Diabet Med 27:175-80. 2010
    ....
  7. doi request reprint Effect of acarbose on postmeal mononuclear blood cell response in patients with early type 2 diabetes: the AI(I)DA study
    M Hanefeld
    Center for Clinical Studies, GWT Dresden, Dresden, Germany
    Horm Metab Res 41:132-6. 2009
    ..Postprandial metabolic and inflammatory parameters were strongly interrelated. These results suggest pleiotropic effects of acarbose, which may contribute to its vasoprotective potentials...
  8. ncbi request reprint Relationship between diurnal glucose levels and HbA1c in type 2 diabetes
    F Pistrosch
    Nephrology, Dept of Medicine, University Hospital, Dresden, Germany
    Horm Metab Res 38:455-9. 2006
    ..The areas under the curve above fasting BG (AUC1) and above 5.6 mmol/l (AUC2) were calculated for further evaluation. Hb (A1c) was measured at baseline and after a mean of 89 (74 to 108) days...
  9. doi request reprint Polymorphisms in perilipin gene (PLIN) are not associated with obesity and weight variation in people with high risk of type 2 diabetes
    A Bergmann
    Health Care Centre of Medical Faculty Carl Gustav Carus of the Technical University Dresden, Dresden, Germany
    Exp Clin Endocrinol Diabetes 116:S56-8. 2008
    ..But some other studies showed that, this association was not significant in Chinese and French . The aim of the current study was to examine whether the associations manifested in a German population with high risk of type 2 diabetes...
  10. ncbi request reprint Glycemic control and treatment failure with pioglitazone versus glibenclamide in type 2 diabetes mellitus: a 42-month, open-label, observational, primary care study
    M Hanefeld
    Centre for Clinical Studies, GWT Technical University, Dresden, Germany
    Curr Med Res Opin 22:1211-5. 2006
    ..It has been suggested that deteriorating glycemic control is related to baseline hemoglobin A(1c) (HbA(1c)) values and remaining beta-cell function...
  11. doi request reprint Relationship between HbA1c on target, risk of silent hypoglycemia and glycemic variability in patients with type 2 diabetes mellitus
    B Engler
    GWT TUD GmbH, Center for Clinical Studies, Dresden, Germany
    Exp Clin Endocrinol Diabetes 119:59-61. 2011
    ..We aimed to compare time spent at low glucose level (silent hypoglycemia, glucose <3.0 mmol/l) and glycemic variability in patients who reached HbA1c <7.0% with those who did not...
  12. ncbi request reprint Once-daily sitagliptin, a dipeptidyl peptidase-4 inhibitor, for the treatment of patients with type 2 diabetes
    Markolf Hanefeld
    GWT Technical University, Dresden, Germany
    Curr Med Res Opin 23:1329-39. 2007
    ..Additionally, the glycemic response to sitagliptin 100 mg daily was evaluated as a once-daily (100 mg once-daily) or twice-daily (50 mg twice-daily) dosing regimen...
  13. ncbi request reprint [The metabolic syndrome: where are we going and for what benefits?]
    M Hanefeld
    Zentrum für Klinische Studien, Forschungsbereich Endokrinologie und Stoffwechsel, GWT, Technische Universität Dresden GmbH, Dresden, Germany
    Dtsch Med Wochenschr 131:S236-9. 2006
    ..Building on a "common soil" for the disease components, optimal treatment can be provided and side effect as well as costs reduced...
  14. ncbi request reprint Comparison of the prevalence of the metabolic syndrome by WHO, AHA/NHLBI, and IDF definitions in a German population with type 2 diabetes: the Diabetes in Germany (DIG) Study
    C Koehler
    Centre for Clinical Study, GWT TUD GmbH, Dresden, Germany
    Horm Metab Res 39:632-5. 2007
    ..The distinctly lower prevalence delineated from WHO criteria is due to low frequency of central obesity and hypertension as consequence of higher cutoff limits for these components used in the WHO definition...
  15. doi request reprint The role of pioglitazone in modifying the atherogenic lipoprotein profile
    M Hanefeld
    GWT TUD GmbH, Centre for Clinical Studies, Department of Metabolic Research and Endocrinology, Dresden Technical University, Dresden, Germany
    Diabetes Obes Metab 11:742-56. 2009
    ..The antidyslipidaemic effects of pioglitazone--in particular, improvements in HDL-C and reduction of small dense LDL3--may have contributed to these effects...
  16. ncbi request reprint [Differential type 2 diabetes therapy based on pathophysiological aspects]
    M Hanefeld
    Zentrum für Klinische Studien, GWT TU Dresden
    Ther Umsch 59:393-401. 2002
    ..Instead of a stepwise treatment algorithm an individualized therapy based on pathophysiology and comorbidities taking into account the global risk seems to be beneficial...
  17. ncbi request reprint Control of post-prandial hyperglycemia--an essential part of good diabetes treatment and prevention of cardiovascular complications
    M Hanefeld
    Center of Clinical Studies, Technical University Dresden, Fiedlerstrasse 34, 01307 Dresden, Germany
    Nutr Metab Cardiovasc Dis 12:98-107. 2002
    ..This article reviews the relationship between the control of post-prandial hyperglycemia and diabetes-related complications...
  18. ncbi request reprint Acarbose reduces the risk for myocardial infarction in type 2 diabetic patients: meta-analysis of seven long-term studies
    M Hanefeld
    Centre for Clinical Studies, GWT, Technical University of Dresden, Fiedlerstrasse 34, 01307 Dresden, Germany
    Eur Heart J 25:10-6. 2004
    ..To assess if treatment with the alpha-glucosidase inhibitor acarbose can reduce cardiovascular events in type 2 diabetic patients...
  19. ncbi request reprint [Hyperlipidemia and fibrates with special reference to diabetes]
    E Henkel
    Zentrum Klinische Studien GWT TU Dresden
    Herz 26:523-30. 2001
    ..A definite answer with respect to the benefit/risk ratio of fibrates should be provided by large ongoing studies with these drugs in representative groups of diabetes patients (LDS, TrUMPET, FIELD)...
  20. ncbi request reprint Outcome studies in type 2 diabetes
    M Hanefeld
    Centre for Clinical Studies, GWT Technical University, Dresden, Germany
    Curr Med Res Opin 21:S41-8. 2005
    ....
  21. ncbi request reprint [History and definition(s) of metabolic syndrome]
    M Hanefeld
    Zentrum für Klinische Studien, Forschungsbereich Endokrinologie und Stoffwechsel, GWT TUD GmbH, 01307, Fiedlerstrasse 34, Dresden, Deutschland
    Internist (Berl) 48:117-25. 2007
    ..Thus, simple, collective diagnostics and therapy for this finely meshed group of diseases together with its risk factors is possible...
  22. ncbi request reprint Different effects of acarbose and glibenclamide on proinsulin and insulin profiles in people with Type 2 diabetes
    M Hanefeld
    Centre for Clinical Studies GWT TU Dresden, Technical University, Dresden, Germany
    Diabetes Res Clin Pract 55:221-7. 2002
    ..In a double-blind, placebo-controlled study, we compared the effect of acarbose (A) and glibenclamide (G) on post-prandial (pp) and 24-h profiles of proinsulin and insulin...
  23. ncbi request reprint An update on preventive and regenerative therapies in diabetes mellitus
    M Reimann
    Department of Internal Medicine III, Medical Faculty Carl Gustav Carus, Dresden University of Technology, Dresden, Germany
    Pharmacol Ther 121:317-31. 2009
    ..Lastly, important efforts to halt disease progression with emphasis on beta-cell regeneration are presented...
  24. ncbi request reprint Improved metabolic control by Ipomoea batatas (Caiapo) is associated with increased adiponectin and decreased fibrinogen levels in type 2 diabetic subjects
    B Ludvik
    Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
    Diabetes Obes Metab 10:586-92. 2008
    ..The present study was designed to further evaluate its mode of action on insulin sensitivity over an extended period of time as well as the effects on fibrinogen and other markers of low-grade inflammation...
  25. ncbi request reprint Effect of rosiglitazone on the frequency of diabetes in patients with impaired glucose tolerance or impaired fasting glucose: a randomised controlled trial
    H C Gerstein
    Lancet 368:1096-105. 2006
    ..The aim of this study was to assess prospectively the drug's ability to prevent type 2 diabetes in individuals at high risk of developing the condition...
  26. ncbi request reprint Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin as monotherapy in patients with type 2 diabetes mellitus
    I Raz
    Diabetes Research Center, Hadassah University Hospital, Jerusalem, Israel
    Diabetologia 49:2564-71. 2006
    ..The aim of this study was to assess the efficacy and safety of sitagliptin (MK-0431) as monotherapy in patients with type 2 diabetes mellitus and inadequate glycaemic control (HbA(1c) > or =7% and < or =10%) on exercise and diet...
  27. ncbi request reprint Long-term effect of octreotide in acromegaly on insulin resistance
    M Breidert
    Medizinische Klinik, , Germany
    Horm Metab Res 27:226-30. 1995
    ..abstract truncated at 250 words)..
  28. ncbi request reprint Prevention of diabetes and cardiovascular disease in patients with impaired glucose tolerance: rationale and design of the Nateglinide And Valsartan in Impaired Glucose Tolerance Outcomes Research (NAVIGATOR) Trial
    Robert M Califf
    Duke Transitional Medicine Institute, Durham, NC 27715, USA
    Am Heart J 156:623-32. 2008
    ..The study was designed to evaluate whether reducing postprandial hyperglycemia, blockade of the renin-angiotensin-aldosterone system, or both interventions reduce the risk of T2DM or cardiovascular events in patients with IGT...
  29. pmc Rosiglitazone RECORD study: glucose control outcomes at 18 months
    P D Home
    Newcastle Diabetes Centre and Newcastle University, UK
    Diabet Med 24:626-34. 2007
    ..To compare glucose control over 18 months between rosiglitazone oral combination therapy and combination metformin and sulphonylurea in people with Type 2 diabetes...
  30. doi request reprint Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes
    Anushka Patel
    N Engl J Med 358:2560-72. 2008
    ..In patients with type 2 diabetes, the effects of intensive glucose control on vascular outcomes remain uncertain...
  31. ncbi request reprint Visfatin: a putative biomarker for metabolic syndrome is not influenced by pioglitazone or simvastatin treatment in nondiabetic patients at cardiovascular risk -- results from the PIOSTAT study
    A Pfutzner
    1Institute for Clinical Research and Development, Mainz, Germany
    Horm Metab Res 39:764-8. 2007
    ....
  32. doi request reprint Effects of ramipril and rosiglitazone on cardiovascular and renal outcomes in people with impaired glucose tolerance or impaired fasting glucose: results of the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) trial
    G R Dagenais
    Laval University Heart and Lung Institute, 2725 Chemin Ste Foy, Quebec, Quebec City, Canada
    Diabetes Care 31:1007-14. 2008
    ..We determined the effects of ramipril and rosiglitazone on combined and individual CVD and renal outcomes in people with IGT and/or IFG in the Diabetes REduction Assessment With ramipril and rosiglitazone Medication (DREAM) trial...
  33. ncbi request reprint Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of Glycaemia in Diabetes (RECORD): study design and protocol
    P D Home
    School of Clinical Medical Sciences Diabetes, University of Newcastle upon Tyne, Medical School, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK
    Diabetologia 48:1726-35. 2005
    ....
  34. ncbi request reprint To: Strey CH, Young J, Collier M, Florkowski CM, Shand BI, Scott RS (2004) The postprandial state does not impair endothelial function in women with Type 2 diabetes irrespective of glycaemic control. Diabetologia 47:1838-1846
    A Ceriello
    Diabetologia 48:1423-4; author reply 1425-6. 2005
  35. ncbi request reprint [Therapy decision based on the glucose triad. Drug treatment of type 2 diabetes]
    M Hanefeld
    Zentrum für Klinische Studien, GWT TU Dresden mbH
    MMW Fortschr Med 145:30-4. 2003
    ..This also applies to the combination with insulin...
  36. ncbi request reprint STOP-NIDDM: a new paradigm for diabetes prevention?
    M Hanefeld
    Nutr Metab Cardiovasc Dis 12:253-8. 2002
  37. ncbi request reprint Influence of treatment with acarbose or glibenclamide on insulin sensitivity in type 2 diabetic patients
    S Fischer
    Institute and Outpatient Department of Clinical Metabolic Research, Medical Faculty Carl Gustav Carus of the Technical University Dresden, Germany
    Diabetes Obes Metab 5:38-44. 2003
    ..The aim of our double-blind, placebo-controlled study was to compare the effect of acarbose and glibenclamide on the insulin sensitivity in type 2 diabetes...
  38. ncbi request reprint Insulin-resistant patients with type 2 diabetes mellitus have higher serum leptin levels independently of body fat mass
    S Fischer
    Institute of Clinical Metabolic Research, Medical Faculty Carl Gustav Carus, University of Technology Dresden, Fetscherstrasse 74, 01307 Dresden, Germany
    Acta Diabetol 39:105-10. 2002
    ..Our data point to a functional relationship between insulin resistance and leptin concentrations in insulin-resistant type 2 diabetic men, independently of body composition. This relationship is believed to be mediated by insulin...
  39. ncbi request reprint Impaired glucose tolerance is not associated with lipid intolerance
    E Henkel
    Centre of Clinical Studies Metabolism and Endocrinology, Science and Technology Transfer GWT, Technial University Dresden, Germany
    Diabetes Nutr Metab 15:84-90. 2002
    ..In conclusion, IGT subjects with a similar level of fasting TG do not exhibit lipid intolerance. Our data suggest that glucose intolerance should precede lipid intolerance...
  40. ncbi request reprint Subclinical inflammation is strongly related to insulin resistance but not to impaired insulin secretion in a high risk population for diabetes
    T Temelkova-Kurktschiev
    Centre for Clinical Studies Metabolism and Endocrinology, Science and Technology Transfer, Technical University Dresden, Germany
    Metabolism 51:743-9. 2002
    ....
  41. ncbi request reprint [The new oral antidiabetics. Type 2 diabetes under control only with tablets?]
    M Hanefeld
    Zentrums für Klinische Studien, Forschungsbereich Endokrinologie u Stoffwechsel, TU Dresden
    MMW Fortschr Med 143:38-42. 2001
    ..However, this fact does not justify delaying treatment with insulin, which is always needed when the goals of treatment cannot be achieved with oral preparations...
  42. ncbi request reprint Improved glycaemic control with miglitol in inadequately-controlled type 2 diabetics
    E Standl
    Schwabing Hospital, Koelner Platz 1, D-80804 Munich, Germany
    Diabetes Res Clin Pract 51:205-13. 2001
    ..No cases of hypoglycaemia were reported. CONCLUSIONS: Miglitol can safely and effectively be added to long-term combination therapy in people with Type 2 diabetes inadequately controlled with glibenclamide plus metformin...
  43. ncbi request reprint [Significance of triglycerides for other metabolic parameters in the familial metabolic syndrome]
    W Metzler
    Medizinische Klinik Leiter U R Fölsch, Universitatsklinikum Schleswig Holstein, Campus Kiel
    Dtsch Med Wochenschr 128:1941-6. 2003
    ..We therefore studied the importance of the triglycerides within a defined glycemic state in patients with an elevated familial risk for metabolic diseases...
  44. ncbi request reprint A long-term comparison of pioglitazone and gliclazide in patients with Type 2 diabetes mellitus: a randomized, double-blind, parallel-group comparison trial
    B H Charbonnel
    Clinique d Endocrinologie, Hotel Dieu, F 44093 Nantes cedex 1, France
    Diabet Med 22:399-405. 2005
    ..This study compared the effects of pioglitazone and gliclazide on metabolic control in drug-naive patients with Type 2 diabetes mellitus...
  45. ncbi request reprint Long-term therapy with addition of pioglitazone to metformin compared with the addition of gliclazide to metformin in patients with type 2 diabetes: a randomized, comparative study
    D R Matthews
    Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital, Oxford, UK
    Diabetes Metab Res Rev 21:167-74. 2005
    ..This 52-week, randomized, double-blind study compared the efficacy and safety of metformin plus pioglitazone with the established combination of metformin plus gliclazide in type 2 diabetes mellitus...
  46. ncbi request reprint [Hyperglycemia and cardiovascular events]
    C A Schneider
    Klinik III fur Innere Medizin, Universitat zu Koln
    Dtsch Med Wochenschr 129:2553-7. 2004
    ..In summary, the early detection and treatment of abnormalities of glucose metabolism reduces cardiac events...
  47. ncbi request reprint Efficacy and safety of pioglitazone versus metformin in patients with type 2 diabetes mellitus: a double-blind, randomized trial
    G Schernthaner
    Department of Medicine I, Rudolfstiftung Hospital, A 1030 Vienna, Austria
    J Clin Endocrinol Metab 89:6068-76. 2004
    ..HbA1c reduction is similar after pioglitazone and metformin monotherapies, but differences in FPG, plasma lipids, and adverse effects between the two compounds may influence decision-making in individual prescribers...
  48. ncbi request reprint [Glucose-independent impact of the glitazones on the cardiovascular outcome]
    M Hanefeld
    Zentrum für Klinische Studien, Forschungsbereich Endokrinologie und Stoffwechsel, TU Dresden
    MMW Fortschr Med 147:37-9. 2005
    ..The first results from the PROactive study--the design of which, together with the data at study begin have already been published--are expected to become available by the end of 2005...
  49. ncbi request reprint Long-term efficacy and tolerability of add-on pioglitazone therapy to failing monotherapy compared with addition of gliclazide or metformin in patients with type 2 diabetes
    B Charbonnel
    Endocrinology Clinic, Hotel Dieu, Place Alexis Ricordeau, 44093, Nantes Cedex 1, France
    Diabetologia 48:1093-104. 2005
    ....
  50. ncbi request reprint Acarbose for the prevention of Type 2 diabetes, hypertension and cardiovascular disease in subjects with impaired glucose tolerance: facts and interpretations concerning the critical analysis of the STOP-NIDDM Trial data
    J L Chiasson
    Research Centre, Centre Hospitalier de l Universite de Montreal Hotel Dieu, Department of Medicine, University of Montreal, 3850 St Urbain Street, Rm 8 202, Montreal, Quebec H2W 1T7, Canada
    Diabetologia 47:969-75; discussion 976-7. 2004
    ..The investigators stand strongly behind these results demonstrating that acarbose treatment is associated with a delay in the development of diabetes, hypertension and cardiovascular complications in a high-risk population with IGT...
  51. ncbi request reprint The metabolic syndrome--a postprandial disease?
    M Hanefeld
    Horm Metab Res 38:435-6. 2006
  52. ncbi request reprint The lipid triad in type 2 diabetes - prevalence and relevance of hypertriglyceridaemia/low high-density lipoprotein syndrome in type 2 diabetes
    T Temelkova-Kurktschiev
    Centre for Clinical Studies, Technical University Dresden, Germany
    Exp Clin Endocrinol Diabetes 112:75-9. 2004
    ..Postprandial HTG was also shown to be correlated with increased IMT in type 2 diabetic patients...
  53. ncbi request reprint Search for mitochondrial DNA mutation at position 3243 in German patients with a positive family history of maternal diabetes mellitus
    T Klemm
    Medical Department III, Leipzig University, Germany
    Exp Clin Endocrinol Diabetes 109:283-7. 2001
    ..6% of the patients. We therefore conclude that the frequency of the A3243G mutation is much lower in the investigated study population, mostly originating from Saxonia, than in asian populations...
  54. ncbi request reprint Effect of the angiotensin II receptor antagonist valsartan on lipid profile and glucose metabolism in patients with hypertension
    M Hanefeld
    Centre for Clinical Studies, Department of Endocrinology and Metabolic Research, Technical University of Dresden, Germany
    J Int Med Res 29:270-9. 2001
    ..In conclusion, in addition to the marked decrease in blood pressure, valsartan significantly reduces total and LDL cholesterol levels and is neutral on glucose metabolism...
  55. ncbi request reprint Subclinical inflammation in newly detected Type II diabetes and impaired glucose tolerance
    T Temelkova-Kurktschiev
    Diabetologia 45:151. 2002
  56. ncbi request reprint [Primary prevention of type 2 diabetes]
    M Hanefeld
    Dtsch Med Wochenschr 127:951-2. 2002
  57. ncbi request reprint [Predictors of abnormal glucose tolerance in persons at risk of type 2 diabetes: the RIAD study]
    E Henkel
    Zentrum für Klinische Studien GWT TU Dresden, Germany
    Dtsch Med Wochenschr 127:953-7. 2002
    ..So far it is not clear which anthropometric and metabolic/hormonal parameters are of importance in the conversion of normal to impaired glucose tolerance...
  58. ncbi request reprint The challenge of the Metabolic Syndrome
    M Hanefeld
    Horm Metab Res 39:625-6. 2007