Research Topics
| Michele WessaSummaryAffiliation: Central Institute of Mental Health Country: Germany Publications
| Collaborators
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Detail Information
Publications
Diffusion tensor tractography in mesencephalic bundles: relation to mental flexibility in detoxified alcohol-dependent subjectsSandra Chanraud
INSERM, U797 Research Unit Neuroimaging and Psychiatry, IFR49, Orsay, France
Neuropsychopharmacology 34:1223-32. 2009....- Microstructural white matter changes in euthymic bipolar patients: a whole-brain diffusion tensor imaging studyMichele Wessa
INSERM, U797, CEA INSERM U797 Neuroimaging and Psychiatry, IFR49, University Paris Sud, University Paris 5, Hospital Department Frederic Joliot, IBM, Orsay, France
Bipolar Disord 11:504-14. 2009..To extend previous findings, we investigated whole-brain modifications in white matter integrity in euthymic bipolar patients with minimal manic and depressive symptoms... - Emotional processing in bipolar disorder: behavioural and neuroimaging findingsMichele Wessa
Department of Cognitive and Clinical Neuroscience, Research Group Emotional Processing in Bipolar Disorder, Central Institute of Mental Health, 68159 Mannheim, Germany
Int Rev Psychiatry 21:357-67. 2009..This imbalance between the two networks has been proposed to underlie deficient emotion regulation in bipolar disorder... 
Failure of extinction of fear responses in posttraumatic stress disorder: evidence from second-order conditioningMichele Wessa
Department of Clinical and Cognitive Neuroscience, University of Heidelberg, Central Institute of Mental Health, Square J 5, 68159 Mannheim, Germany
Am J Psychiatry 164:1684-92. 2007..The extinction of the traumatic response might be impeded if trauma reminders maintain fear responses by their association with the original trauma through second-order conditioning...- Fronto-striatal overactivation in euthymic bipolar patients during an emotional go/nogo taskMichele Wessa
Inserm U797, CEA INSERM Research Unit Neuroimaging and Psychiatry, IFR49, University Paris Sud 11 and University Paris 5, Hospital Department Frederic Joliot, 91401 Orsay, France
Am J Psychiatry 164:638-46. 2007..The authors examined the emotional modulation of cognitive processes and its underlying neural mechanisms in euthymic bipolar patients... - Central and peripheral psychophysiological responses to trauma-related cues in subclinical posttraumatic stress disorder: a pilot studyMichele Wessa
Department of Neuropsychology and Clinical Psychology at the University of Heidelberg, Central Institute of Mental Health, J5, 68159, Mannheim, Germany
Exp Brain Res 167:56-65. 2005.... - Increased medial orbitofrontal and amygdala activation: evidence for a systems-level endophenotype of bipolar I disorderJulia Linke
Department of Cognitive and Clinical Neuroscience, Central Institute of Mental Health in Mannheim, Germany
Am J Psychiatry 169:316-25. 2012.... 
Cortical folding in patients with bipolar disorder or unipolar depressionJani Penttilä
INSERM, U797 Research Unit Neuroimaging and Psychiatry, CEA, Hospital Department Frédéric Joliot and Neurospin, Paris Sud University, Orsay, France
J Psychiatry Neurosci 34:127-35. 2009..We hypothesized that patients with treatment-resistant depression would exhibit measurable alterations in cortical folding...- How to regulate emotion? Neural networks for reappraisal and distractionPhilipp Kanske
Department of Cognitive and Clinical Neuroscience, Central Institute of Mental Health, Mannheim, Germany
Cereb Cortex 21:1379-88. 2011..Functional connectivity patterns of the amygdala activation confirmed the roles of these specific activations for the 2 emotion regulation strategies... - A meta-analysis of neurofunctional imaging studies of emotion and cognition in major depressionCarsten Diener
Department of Cognitive and Clinical Neuroscience, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Germany
Neuroimage 61:677-85. 2012.... - Context conditioning and extinction in humans: differential contribution of the hippocampus, amygdala and prefrontal cortexSimone Lang
Department of Clinical and Cognitive Neuroscience, Central Institute of Mental Health, University of Heidelberg, Mannheim, Germany
Eur J Neurosci 29:823-32. 2009..These data are consistent with theoretical models that propose an inhibitory effect of the mPFC on the amygdala. The interaction of the mPFC with the hippocampus may reflect the context-specificity of extinction learning... - Genome-wide supported risk variant for bipolar disorder alters anatomical connectivity in the human brainJulia Linke
Department of Cognitive and Clinical Neuroscience, Central Institute of Mental Health, Mannheim, Germany
Neuroimage 59:3288-96. 2012..In sum, our findings show that ANK3 rs10994336 or a variant in linkage-disequilibrium is functional in the human brain and also influences behavioral phenotypes related to bipolar disorder... - Microstructure of a three-way anatomical network predicts individual differences in response inhibition: a tractography studyAndrea V King
Department of Cognitive and Clinical Neuroscience, Central Institute of Mental Health, University of Heidelberg, Square J5, 68159 Mannheim, Germany
Neuroimage 59:1949-59. 2012..These findings point to a specific contribution of white matter pathways connecting distinct basal ganglia structures with both medial frontal and ventrolateral prefrontal regions to response inhibition... - Sensitivity to positive and negative feedback in euthymic patients with bipolar I disorder: the last episode makes the differenceJulia Linke
Department of Cognitive and Clinical Neuroscience, Central Institute of Mental Health, Mannheim, Germany
Bipolar Disord 13:638-50. 2011.... - An agent harms a victim: a functional magnetic resonance imaging study on specific moral emotionsGayannee Kedia
INSERM, U797 Orsay, France
J Cogn Neurosci 20:1788-98. 2008..e., the bilateral amygdala, anterior cingulate, and basal ganglia). These results suggest that specific moral emotions induce different neural activity depending on the extent to which they involve the self and other... - Retrieval and emotional processing of traumatic memories in posttraumatic stress disorder: peripheral and central correlatesMichele Wessa
Department of Clinical and Cognitive Neuroscience at the University of Heidelberg, Central Institute of Mental Health, J 5, 68159 Mannheim, Germany
Neuropsychologia 44:1683-96. 2006..These findings are discussed in the context of current models of the role of declarative memory in the development and maintenance of PTSD... - Neuroimaging-based markers of bipolar disorder: evidence from two meta-analysesJosselin Houenou
INSERM, U 955, IMRB, Department of Medical Genomic, Psychiatry Genetic Team, University Paris Est Creteil, Creteil, F 94000, France
J Affect Disord 132:344-55. 2011..The identification of objective biomarkers, such as functional and structural brain abnormalities of BD might improve diagnosis and help elucidate its pathophysiology... - Enhanced stress analgesia to a cognitively demanding task in patients with posttraumatic stress disorderSlawomira J Diener
Department of Cognitive and Clinical Neuroscience, Central Institute of Mental Health, University of Heidelberg, Mannheim, Germany
J Affect Disord 136:1247-51. 2012..In posttraumatic stress disorder (PTSD) exaggerated stress-induced analgesia to trauma reminders was proposed. The present study investigated whether enhanced analgesia occurs in response to a trauma-unrelated cognitive stressor in PTSD... - Loss of callosal fibre integrity in healthy elderly with age-related white matter changesMartin Griebe
Department of Neurology, Universitatsmedizin Mannheim, University of Heidelberg, Theodor Kutzer Ufer 1 3, 68167 Mannheim, Germany
J Neurol 258:1451-9. 2011..Loss of tissue integrity and atrophy of the CC secondary to spatially remote lesions in the peri- and paraventricular white matter in ARWMC appear to be already detectable in healthy elderly individuals... - Brain correlates of stress-induced analgesiaPinar Yilmaz
Department of Clinical and Cognitive Neuroscience, Central Institute of Mental Health, University of Heidelberg, Mannheim, Germany
Pain 151:522-9. 2010..SIA seems to activate similar brain networks as placebo analgesia or analgesia mediated by diffuse noxious inhibitory controls and involved sensory, affective and cognitive modulatory circuits... - Cortical folding difference between patients with early-onset and patients with intermediate-onset bipolar disorderJani Penttilä
INSERM, U797 Research Unit Neuroimaging and Psychiatry, France
Bipolar Disord 11:361-70. 2009..We searched for cortical folding differences between early-onset (before 25 years) and intermediate-onset (between 25 and 45 years) BD patients... - [Posttraumatic stress disorder and trauma memory--a psychobiological perspective]Michele Wessa
Lehrstuhl für Neuropsychologie an der Ruprecht Karls Universität Heidelberg, Zentralinstitut fur Seelische Gesundheit, J 5, D 68159 Mannheim, Germany
Z Psychosom Med Psychother 48:28-37. 2002..This dissociation of implicit and explicit memory prevents the extinction of the emotional response to the trauma and perpetuates the disorder. First empirical results based on this model confirm the main hypotheses... - Goal-directed behavior under emotional distraction is preserved by enhanced task-specific activationMichele Wessa
Section for Experimental Psychopathology and Neuroimaging, Department of General Psychiatry, Center for Psychosocial Medicine, University of Heidelberg, Vossstrasse 4, Heidelberg, Germany
Soc Cogn Affect Neurosci 8:305-12. 2013..Similar error rates in both conditions indicate that cognitive task performance is preserved through enhanced recruitment of task-specific neural resources when emotional distracter stimuli are present... - Neural correlates of emotion regulation deficits in remitted depression: the influence of regulation strategy, habitual regulation use, and emotional valencePhilipp Kanske
Section for Experimental Psychopathology and Neuroimaging, Department of General Psychiatry, Center for Psychosocial Medicine, Heidelberg University, Germany
Neuroimage 61:686-93. 2012..This interpretation is supported by the relation of habitual reappraisal use to amygdala down-regulation success... - Motivational orientation modulates the neural response to rewardJulia Linke
Department of Cognitive and Clinical Neuroscience, Central Institute of Mental Health, Mannheim, Germany
Neuroimage 49:2618-25. 2010.... - Altered cortisol awakening response in posttraumatic stress disorderMichele Wessa
Department of Clinical and Cognitive Neuroscience, Central Institute of Mental Health, University of Heidelberg, J 5, 68159 Mannheim, Germany
Psychoneuroendocrinology 31:209-15. 2006..The findings are discussed in light of the hypothesis of a counterregulation of hyper-arousal symptoms and chronic stress in PTSD... - Psychometric qualities of the German version of the Posttraumatic Diagnostic Scale (PTDS)Dorothee Griesel
Department of Cognitive and Clinical Neuroscience, University of Heidelberg, Central Institute of Mental Health, Mannheim, Germany
Psychol Assess 18:262-8. 2006..The findings are discussed with respect to their equivalency to the original PTDS, core symptoms of PTSD, and desirable future research...