Research Topics
| M BohusSummaryAffiliation: Central Institute of Mental Health Country: Germany Publications
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Detail Information
Publications
The short version of the Borderline Symptom List (BSL-23): development and initial data on psychometric propertiesMartin Bohus
Department of Psychosomatics and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
Psychopathology 42:32-9. 2009..The BSL-95 includes 95 items. In order to reduce patient burden and assessment time, a short version with 23 items (BSL-23) was developed...
[Mindfulness-based psychotherapy]M Bohus
Zentralinstitut fur Seelische Gesundheit, Klinik für Psychosomatik und Psychotherapeutische Medizin, Postfach 122120, 68072 Mannheim, Deutschland
Nervenarzt 83:1479-87; quiz 1488-9. 2012..In summary, mindfulness used as one component in modular conceptualized treatment programs seems to be both acceptable and effective...
[General principles in psychotherapy of personality disorders]Martin Bohus
Abteilung für Psychosomatik und Psychotherapeutische Medizin, Zentralinstitut fur Seelische Gesundheit Mannheim
Psychother Psychosom Med Psychol 59:149-57. 2009..The intention was to develop a concept which gets beyond the school oriented therapeutic approaches in order to provide the platform for further developments of general and specific treatments for personality disorders...
[Dialectical behavior therapy for posttraumatic stress disorder in survivors of childhood sexual abuse]Martin Bohus
Zentralinstitut fur Seelische Gesundheit, Klinik für Psychosomatik und Psychotherapeutische Medizin, Mannheim
Psychother Psychosom Med Psychol 61:140-7. 2011..An overview is given on the treatment rational, the dynamic hierarchy of treatment focusses and the interventions used. In the internet version of this article treatment application is exemplified in a case study...
[Psychopathology and psychotherapy of borderline personality disorder: state of the art]M Bohus
Zentralinstitut fur Seelische Gesundheit Mannheim, Klinik fur Psychosomatische Medizin und Psychotherapie, Mannheim, Germany
Nervenarzt 82:16-24. 2011..This is mirrored by the annual costs for inpatient treatment extending to 4 billion Euros, which is approximately 20% of the total costs for psychiatric care in Germany...
Psychometric properties of the Borderline Symptom List (BSL)Martin Bohus
Department of Psychosomatics and Psychotherapy, Central Institute of Mental Health Mannheim, Mannheim, Germany
Psychopathology 40:126-32. 2007..The psychometric properties and validity of the BSL have been investigated in several studies...
Script-driven imagery of self-injurious behavior in patients with borderline personality disorder: a pilot FMRI studyA Kraus
Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
Acta Psychiatr Scand 121:41-51. 2010..Self-injurious behavior (SIB) is one of the most distinctive features of borderline personality disorder (BPD) and related to impulsivity and emotional dysregulation...
Differentiation of pain ratings in combat-related posttraumatic stress disorderAnja Kraus
Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
Pain 143:179-85. 2009..Our results suggest an association of PTSD with reduced pain sensitivity, which could be related to PTSD-related (neuro-)psychological alterations or to a pre-existing risk factor for the disorder...
A cross-sectional investigation of discontinuation of self-injury and normalizing pain perception in patients with borderline personality disorderP Ludascher
Department of Psychosomatic Medicine, Central Institute of Mental Health, Mannheim
Acta Psychiatr Scand 120:62-70. 2009..The aim of the present study was to test whether pain perception in patients with current SIB is different from that of patients who had stopped SIB, and whether pain perception of the latter group differs from healthy controls (HC)...
Amygdala deactivation as a neural correlate of pain processing in patients with borderline personality disorder and co-occurrent posttraumatic stress disorderAnja Kraus
Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
Biol Psychiatry 65:819-22. 2009..This study aimed at clarifying whether central antinoceptive mechanisms discriminate BPD patients with and without co-occurrent PTSD...
Oligodipsia and dissociative experiences in borderline personality disorderK Hoeschel
Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
Acta Psychiatr Scand 117:390-3. 2008....
Do improvements after inpatient dialectial behavioral therapy persist in the long term? A naturalistic follow-up in patients with borderline personality disorderNikolaus Kleindienst
Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
J Nerv Ment Dis 196:847-51. 2008..The effects of inpatient dialectical behavior therapy seem to persist after patients returned to their usual lives...
Affective dysregulation and dissociative experience in female patients with borderline personality disorder: a startle response studyUlrich W Ebner-Priemer
Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, Postfach 12 21 20, 68072 Mannheim, Germany
J Psychiatr Res 39:85-92. 2005..Furthermore, it highlights the importance of assessing present-state dissociation in basic research as well as psychotherapy...
State affective instability in borderline personality disorder assessed by ambulatory monitoringUlrich W Ebner-Priemer
Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, University of Heidelberg, Germany
Psychol Med 37:961-70. 2007..Furthermore, the pattern of instability that characterizes BPD has not yet been identified...
Psychophysiological ambulatory assessment of affective dysregulation in borderline personality disorderUlrich W Ebner-Priemer
Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, Postfach 122120, 68072 Mannheim, Germany
Psychiatry Res 150:265-75. 2007..M., 1993. Cognitive-Behavioral Treatment of Borderline Personality Disorder. The Guildford Press, New York.] and suggest the potential utility for evaluating treatment outcome...
Motives for nonsuicidal self-injury among women with borderline personality disorderNikolaus Kleindienst
Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
J Nerv Ment Dis 196:230-6. 2008..NSSI was usually preceded by a large variety of negative feelings that were reported to clearly improve with NSSI. In conclusion, therapists should anticipate a multidimensional functional spectrum when exploring motives of NSSI...
Distress and affective dysregulation in patients with borderline personality disorder: a psychophysiological ambulatory monitoring studyUlrich W Ebner-Priemer
Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, 68072 Mannheim, Germany
J Nerv Ment Dis 196:314-20. 2008..Physiological arousal (heart rate) was related to distress in both groups. Our empirical findings emphasize training in labeling emotions and distress tolerance interventions in treatment for BPD...
A valence-dependent group-specific recall bias of retrospective self-reports: a study of borderline personality disorder in everyday lifeUlrich W Ebner-Priemer
Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
J Nerv Ment Dis 194:774-9. 2006..A traditional questionnaire approach does not distinguish between symptoms of the disorder and recall bias, although the pathological mechanisms underlying them as well as the appropriate treatment strategies may be different...
Emotional learning during dissociative states in borderline personality disorderUlrich W Ebner-Priemer
Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, University of Heidelberg, Germany
J Psychiatry Neurosci 34:214-22. 2009..The aim of our study was to determine whether high states of dissociative experience would specifically alter emotional learning, but not declarative knowledge...
Pain sensitivity and neural processing during dissociative states in patients with borderline personality disorder with and without comorbid posttraumatic stress disorder: a pilot studyPetra Ludäscher
Central Institute of Mental Health, Department of Psychosomatic Medicine and Psychotherapy, Mannheim, Germany
J Psychiatry Neurosci 35:177-84. 2010..Our aim was to investigate the psychologic, somatosensory (pain sensitivity) and neural correlates of dissociative states in patients with these disorders...
Correlation of glutamate levels in the anterior cingulate cortex with self-reported impulsivity in patients with borderline personality disorder and healthy controlsMareen Hoerst
Department of Neuroimaging, Central Institute of Mental Health, Mannheim, Germany
Arch Gen Psychiatry 67:946-54. 2010..Impulsivity is a key feature of BPD and can be related to anterior cingulate cortex function...
Affect regulation and pain in borderline personality disorder: a possible link to the understanding of self-injuryInga Niedtfeld
Department of Psychosomatic Medicine, Central Institute of Mental Health Mannheim, University of Heidelberg, Heidelberg, Germany
Biol Psychiatry 68:383-91. 2010..Pain in BPD has further been observed to lead to a reduction in neural activity in the amygdala and anterior cingulate cortex, which may be attributed to patients' perception of relaxation...
Differential nociceptive deficits in patients with borderline personality disorder and self-injurious behavior: laser-evoked potentials, spatial discrimination of noxious stimuli, and pain ratingsChristian Schmahl
Institute of Physiology and Pathophysiology, Johannes Gutenberg University, Mannheim, Germany
Pain 110:470-9. 2004..These findings suggest that hypoalgesia in BPD may primarily be due to altered intracortical processing similar to certain meditative states...
Pain sensitivity is reduced in borderline personality disorder, but not in posttraumatic stress disorder and bulimia nervosaChristian Schmahl
Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
World J Biol Psychiatry 11:364-71. 2010..To establish whether these findings are specific for BPD, we compared pain thresholds in patients with BPD, posttraumatic stress disorder (PTSD), bulimia nervosa, and healthy controls...
Neural correlates of antinociception in borderline personality disorderChristian Schmahl
Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
Arch Gen Psychiatry 63:659-67. 2006..We predicted that heat stimuli in patients with BPD would activate brain areas concerned with cognitive and emotional evaluation of pain...
Metabolic alterations in the amygdala in borderline personality disorder: a proton magnetic resonance spectroscopy studyMareen Hoerst
Department of Neuroimaging, Central Institute of Mental Health, 68159 Mannheim, Germany
Biol Psychiatry 67:399-405. 2010..0 T in which we acquire data within only the small amygdala. The purpose of this study was to determine alterations of the metabolism in the amygdala in BPD patients...
Hippocampus and amygdala volumes in patients with borderline personality disorder with or without posttraumatic stress disorderChristian Schmahl
Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
J Psychiatry Neurosci 34:289-95. 2009..Both groups exhibit volume reductions of the hippocampus and amygdala. Our aim was to investigate the influence of comorbid PTSD on hippocampus and amygdala volumes in patients with BPD...
[Psychopathology and treatment of borderline personality disorder]M Bohus
Klinik für Psychosomatik und Psychotherapeutische Medizin, Zentralinstitut fur Seelische Gesundheit, Mannheim, J5, 68117, Mannheim
Nervenarzt 78:1069-80; quiz 1081. 2007..Studies on psychopharmacological treatment with promising results have also recently been published. Sufficient outpatient treatment by trained psychotherapists is underdeveloped. Hence, specialized inpatient centers assume this task...
[Development of the "Mannheim Multicomponent Stress Test" (MMST)]Tatyana Kolotylova
Zentralinstitut fur Seelische Gesundheit Mannheim, Klinik für Psychosomatik und Psychotherapeutische Medizin, Universitat Jena, Jena, Germany
Psychother Psychosom Med Psychol 60:64-72. 2010..We conclude that the Mannheim Multicomponent Stress Test (MMST) induces high levels of physiological and psychological stress and can serve as an economical method to investigate stress reactions in a laboratory setting...
New developments in the neurobiology of borderline personality disorderMartin Bohus
Central Institute of Mental Health Mannheim, University of Heidelberg, J 5, 68159 Mannheim, Germany
Curr Psychiatry Rep 6:43-50. 2004..Most of the neuropsychologic, physiologic, endocrinologic, and neuroimaging data support the theory that a dual brain pathology, affecting prefrontal and limbic circuits, may underlie this hyperarousal-dyscontrol syndrome...
Influence of emotional distraction on working memory performance in borderline personality disorderA Krause-Utz
Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
Psychol Med 42:2181-92. 2012..Although current theories emphasize the disruptive potential of negative emotions on cognitive functioning in BPD, behavioral and neurobiological data on this relationship are still lacking...
[Short version of the borderline symptom list (BSL-23): development and psychometric evaluation]Martina Wolf
Klinik für Psychosomatik und Psychotherapeutische Medizin, Zentralinstitut fur Seelische Gesundheit, Mannheim
Psychother Psychosom Med Psychol 59:321-4. 2009..The results indicate that the BSL-23 is an efficient and convenient self-rating instrument that displays very good psychometric properties comparable to those of the full version of the BSL...
Emotional modulation of pain: a clinical perspectiveIris Klossika
Department of Psychosomatic Medicine and Psychotherapy, University of Heidelberg, Central Institute of Mental Health, Mannheim, Germany
Pain 124:264-8. 2006
Increased delta power and discrepancies in objective and subjective sleep measurements in borderline personality disorderAlexandra Philipsen
Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Haupt strasse 5, 79104 Freiburg, Germany
J Psychiatr Res 39:489-98. 2005..Earlier findings in sleep EEG abnormalities in BPD may have been confounded by concomitant depressive symptoms...
Altered pain processing in veterans with posttraumatic stress disorderElbert Geuze
Department of Military Psychiatry, Central Military Hospital, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
Arch Gen Psychiatry 64:76-85. 2007..Several brain areas related to pain processing are implicated in PTSD. To our knowledge, no functional imaging study has discussed whether patients with PTSD experience and process pain in a different way than control subjects...
Frontolimbic brain abnormalities in patients with borderline personality disorder: a volumetric magnetic resonance imaging studyLudger Tebartz van Elst
Department of Psychiatry and Psychotherapy, University of Freiburg, Freiburg, Germany
Biol Psychiatry 54:163-71. 2003....
Effectiveness of inpatient dialectical behavioral therapy for borderline personality disorder: a controlled trialMartin Bohus
Department of Psychiatry and Psychotherapy with Polyclinic, Albert Ludwig University of Freiburg, Medical School, Hauptstrasse 5, D 79104 Freiburg, Germany
Behav Res Ther 42:487-99. 2004..Within a relatively short time frame, improvement was found across a broad range of psychopathological features. Stability of the recovery after one month following discharge, however, was not evaluated and requires further study...
Clonidine in acute aversive inner tension and self-injurious behavior in female patients with borderline personality disorderAlexandra Philipsen
Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Freiburg, Germany
J Clin Psychiatry 65:1414-9. 2004..Further placebo-controlled studies with larger populations are needed to confirm this finding...
Subtype differentiation of patients with borderline personality disorder using a circumplex model of interpersonal behaviorFlorian Leihener
1 Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Hauptstr. 5, D-79104 Freiburg, Germany
J Nerv Ment Dis 191:248-54. 2003..Implications of these findings for future research and management of BPD are discussed...
Neuroimaging of pain perception in Dutch veterans with and without posttraumatic stress disorder: preliminary resultsElbert Geuze
Department of Military Psychiatry, Central Military Hospital, Heidelberglaan, 100 3584, CX, Utrecht, The Netherlands
Ann N Y Acad Sci 1071:401-4. 2006..Fixed affects analysis demonstrated that stimuli subjectively perceived as more painful resulted in increased activation of the caudal ACC, whereas less painful stimuli resulted in increased activation of the rostral ACC in both groups...
Elevated pain thresholds correlate with dissociation and aversive arousal in patients with borderline personality disorderPetra Ludäscher
Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Germany
Psychiatry Res 149:291-6. 2007..Measuring electric pain thresholds is a valid and reasonable method for larger studies...
Shame and implicit self-concept in women with borderline personality disorderNICOLAS RUSCH
Department of Psychiatry and Psychotherapy, University of Freiburg, Hauptstrasse 5, D 79104 Freiburg, Germany
Am J Psychiatry 164:500-8. 2007....
The impact of posttraumatic stress disorder on dysfunctional implicit and explicit emotions among women with borderline personality disorderNICOLAS RUSCH
Department of Psychiatry and Psychotherapy, University of Freiburg, Freiburg, Germany
J Nerv Ment Dis 195:537-9. 2007..Self-reported guilt proneness and implicit anxiety may mediate the negative impact of comorbid PTSD on women with BPD...
Self-stigma in women with borderline personality disorder and women with social phobiaNICOLAS RUSCH
Department of Psychiatry and Psychotherapy, University of Freiburg, Germany
J Nerv Ment Dis 194:766-73. 2006..This may reflect intense labeling processes as being mentally ill due to repeated hospitalizations, frequent interpersonal difficulties, and visible scars...
[Development and characteristics of Dissociation-Tension-Scale acute (DSS-Akute)]Christian E Stiglmayr
Freie Universitat Berlin, Arbeitsbereich für Psychotherapie und Beratung
Psychother Psychosom Med Psychol 53:287-94. 2003..The DSS-acute is a reliable and valid instrument to assess present-time dissociative experiences as well as aversive inner tension. Current studies should further proof the sensitivity for changing symptomatology...
Attention-deficit hyperactivity disorder as a potentially aggravating factor in borderline personality disorderAlexandra Philipsen
Department of Psychiatry and Psychotherapy, University Medical Center, Freiburg, Germany
Br J Psychiatry 192:118-23. 2008..Clinical experience suggests that people with borderline personality disorder often meet criteria for attention-deficit hyperactivity disorder (ADHD). However, empirical data are sparse...
Borderline personality disorderKlaus Lieb
Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Hauptstrasse 5, D 79104 Freiburg, Germany
Lancet 364:453-61. 2004..Current strategies are focusing on the neurobiological underpinnings of the disorder and the development and dissemination of better and more cost-effective treatments to clinicians...
[Dialectical behavior therapy in borderline syndrome: a way out of the therapeutic dead end]Heike Barthruff
, Freiburg
Pflege Z 57:534-7. 2004
Increased diurnal salivary cortisol in women with borderline personality disorderKlaus Lieb
Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Hauptstr 5, D 79104 Freiburg, Germany
J Psychiatr Res 38:559-65. 2004..Increased adrenal activity and lowered feedback sensitivity of the HPA-axis may characterise BPD. Further studies have to reveal reasons of heightened adrenal activity in these patients...
Measuring shame and guilt by self-report questionnaires: a validation studyNICOLAS RUSCH
Department of Psychiatry and Psychotherapy, University of Freiburg, Hauptstrasse 5, D 79104 Freiburg, Germany
Psychiatry Res 150:313-25. 2007..The discriminant validity of the TOSCA-3 to distinguish between shame- and guilt-proneness may be diminished in clinical samples. The measure of state shame (ESS) showed a large overlap with state anxiety...
Self-stigma, empowerment, and perceived legitimacy of discrimination among women with mental illnessNICOLAS RUSCH
Department of Psychiatry and Psychotherapy, University of Freiburg, Germany
Psychiatr Serv 57:399-402. 2006..The authors hypothesized that a high level of perceived discrimination, little sense of identification with the group of people with mental illness, and a high level of perceived legitimacy of discrimination lead to self-stigma...
A critique of the American psychiatric practice guideline for the treatment of patients with borderline personality disorderCynthia Sanderson
University of Massachusetts Medical College, USA
J Personal Disord 16:122-9. 2002
