Katja Becker

Summary

Affiliation: Central Institute of Mental Health
Country: Germany

Publications

  1. ncbi request reprint Role of electroencephalography in attention-deficit hyperactivity disorder
    Katja Becker
    Department of Child and Adolescent Psychiatry and Psychotherapy Central Institute of Mental Health, PO Box 12 21 20, D 68072, Mannheim, Germany
    Expert Rev Neurother 6:731-9. 2006
  2. ncbi request reprint Is the serotonin transporter polymorphism (5-HTTLPR) associated with harm avoidance and internalising problems in childhood and adolescence?
    K Becker
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    J Neural Transm 114:395-402. 2007
  3. ncbi request reprint [Dopaminergic polymorphisms and regulatory problems in infancy]
    Katja Becker
    Klinik für Psychiatrie und Psychotherapie des Kindes und Jugendalters am Zentralinstitut für Seelische Gesundheit, Mannheim
    Z Kinder Jugendpsychiatr Psychother 35:145-51. 2007
  4. doi request reprint Impact of psychosocial adversity on alcohol intake in young adults: moderation by the LL genotype of the serotonin transporter polymorphism
    Manfred Laucht
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    Biol Psychiatry 66:102-9. 2009
  5. doi request reprint Impact of age at first drink on vulnerability to alcohol-related problems: testing the marker hypothesis in a prospective study of young adults
    Arlette F Buchmann
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, 68159 Mannheim, Germany
    J Psychiatr Res 43:1205-12. 2009
  6. doi request reprint Interaction between the 5-HTTLPR serotonin transporter polymorphism and environmental adversity for mood and anxiety psychopathology: evidence from a high-risk community sample of young adults
    Manfred Laucht
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    Int J Neuropsychopharmacol 12:737-47. 2009
  7. doi request reprint Genetic variation in dopamine pathways differentially associated with smoking progression in adolescence
    Manfred Laucht
    Central Institute of Mental Health, Department of Child and Adolescent Psychiatry and Psychotherapy, P O Box 122120, D 68072 Mannheim, Germany
    J Am Acad Child Adolesc Psychiatry 47:673-81. 2008
  8. doi request reprint Evidence for epistasis between the 5-HTTLPR and the dopamine D4 receptor polymorphisms in externalizing behavior among 15-year-olds
    Sarah Hohmann
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, J 5, 68159 Mannheim, Germany
    J Neural Transm 116:1621-9. 2009
  9. doi request reprint The interaction between the dopamine transporter gene and age at onset in relation to tobacco and alcohol use among 19-year-olds
    Brigitte Schmid
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    Addict Biol 14:489-99. 2009
  10. doi request reprint From regulatory problems in infancy to attention-deficit/hyperactivity disorder in childhood: a moderating role for the dopamine D4 receptor gene?
    Katja Becker
    Department of Child and Adolescent Psychiatry and Psychotherapy, Medical Faculty, Philipps University Marburg, Marburg, Germany
    J Pediatr 156:798-803, 803.e1-803.e2. 2010

Collaborators

Detail Information

Publications37

  1. ncbi request reprint Role of electroencephalography in attention-deficit hyperactivity disorder
    Katja Becker
    Department of Child and Adolescent Psychiatry and Psychotherapy Central Institute of Mental Health, PO Box 12 21 20, D 68072, Mannheim, Germany
    Expert Rev Neurother 6:731-9. 2006
    ....
  2. ncbi request reprint Is the serotonin transporter polymorphism (5-HTTLPR) associated with harm avoidance and internalising problems in childhood and adolescence?
    K Becker
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    J Neural Transm 114:395-402. 2007
    ..There were no moderating effects of early life stress or gender. An explanation for the negative findings is that the S allele may be a necessary but not sufficient component cause in a composite risk factor...
  3. ncbi request reprint [Dopaminergic polymorphisms and regulatory problems in infancy]
    Katja Becker
    Klinik für Psychiatrie und Psychotherapie des Kindes und Jugendalters am Zentralinstitut für Seelische Gesundheit, Mannheim
    Z Kinder Jugendpsychiatr Psychother 35:145-51. 2007
    ..We investigated whether or not the severity of the above-mentioned dopaminergic polymorphisms is associated with regulatory disorders in infancy...
  4. doi request reprint Impact of psychosocial adversity on alcohol intake in young adults: moderation by the LL genotype of the serotonin transporter polymorphism
    Manfred Laucht
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    Biol Psychiatry 66:102-9. 2009
    ..The present study aims to further explore G x E between 5-HTTLPR and exposure to psychosocial adversity on alcohol consumption in a high-risk community sample of young adults...
  5. doi request reprint Impact of age at first drink on vulnerability to alcohol-related problems: testing the marker hypothesis in a prospective study of young adults
    Arlette F Buchmann
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, 68159 Mannheim, Germany
    J Psychiatr Res 43:1205-12. 2009
    ....
  6. doi request reprint Interaction between the 5-HTTLPR serotonin transporter polymorphism and environmental adversity for mood and anxiety psychopathology: evidence from a high-risk community sample of young adults
    Manfred Laucht
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    Int J Neuropsychopharmacol 12:737-47. 2009
    ..No evidence for GxE was obtained with regard to current stressful life events and trait anxiety. One possible source for the conflicting findings might be attributed to heterogeneity in depression phenotypes and environmental adversity...
  7. doi request reprint Genetic variation in dopamine pathways differentially associated with smoking progression in adolescence
    Manfred Laucht
    Central Institute of Mental Health, Department of Child and Adolescent Psychiatry and Psychotherapy, P O Box 122120, D 68072 Mannheim, Germany
    J Am Acad Child Adolesc Psychiatry 47:673-81. 2008
    ..To clarify the nature of the association between dopamine genes and smoking by examining whether genetic variability in components of the dopamine pathway could explain refined phenotypes in adolescent smoking progression...
  8. doi request reprint Evidence for epistasis between the 5-HTTLPR and the dopamine D4 receptor polymorphisms in externalizing behavior among 15-year-olds
    Sarah Hohmann
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, J 5, 68159 Mannheim, Germany
    J Neural Transm 116:1621-9. 2009
    ..This result suggests an effect of 5-HTTLPR on externalizing behavior in the presence of DRD4 7r but no effect in its absence...
  9. doi request reprint The interaction between the dopamine transporter gene and age at onset in relation to tobacco and alcohol use among 19-year-olds
    Brigitte Schmid
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    Addict Biol 14:489-99. 2009
    ..Further studies are required to confirm these findings...
  10. doi request reprint From regulatory problems in infancy to attention-deficit/hyperactivity disorder in childhood: a moderating role for the dopamine D4 receptor gene?
    Katja Becker
    Department of Child and Adolescent Psychiatry and Psychotherapy, Medical Faculty, Philipps University Marburg, Marburg, Germany
    J Pediatr 156:798-803, 803.e1-803.e2. 2010
    ..To examine whether the dopamine receptor D4 gene (DRD4) exon III VNTR moderates the risk of infants with regulatory disorders for developing attention-deficit/hyperactivity disorder (ADHD) later in childhood...
  11. doi request reprint Interaction of dopamine transporter genotype with prenatal smoke exposure on ADHD symptoms
    Katja Becker
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    J Pediatr 152:263-9. 2008
    ....
  12. doi request reprint From nature versus nurture, via nature and nurture, to gene x environment interaction in mental disorders
    Anne Kathrin Wermter
    Department of Child and Adolescent Psychiatry and Psychotherapy, Philipps University of Marburg, Hans Sachs Strasse 6, Marburg, Germany
    Eur Child Adolesc Psychiatry 19:199-210. 2010
    ..In future we need larger, sufficiently powered studies that include a detailed and sophisticated characterization of both phenotype and the environmental risk...
  13. ncbi request reprint Visual exploratory behaviour in infancy and novelty seeking in adolescence: two developmentally specific phenotypes of DRD4?
    Manfred Laucht
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    J Child Psychol Psychiatry 47:1143-51. 2006
    ..The present study was designed to investigate the association between visual exploratory behaviour in early infancy, novelty seeking in adolescence, and the dopamine D4 receptor (DRD4) genotype...
  14. ncbi request reprint Interacting effects of the dopamine transporter gene and psychosocial adversity on attention-deficit/hyperactivity disorder symptoms among 15-year-olds from a high-risk community sample
    Manfred Laucht
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    Arch Gen Psychiatry 64:585-90. 2007
    ..Recent evidence suggests that gene x environment interactions could explain the inconsistent findings of association studies relating the dopamine transporter (DAT1) gene with attention-deficit/hyperactivity disorder (ADHD)...
  15. ncbi request reprint Novelty seeking involved in mediating the association between the dopamine D4 receptor gene exon III polymorphism and heavy drinking in male adolescents: results from a high-risk community sample
    Manfred Laucht
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    Biol Psychiatry 61:87-92. 2007
    ..The aim of this study was to examine whether allelic variants of the dopamine D4 receptor gene (DRD4) are associated with alcohol use in adolescents and to determine the extent to which these links are mediated by NS...
  16. ncbi request reprint Rolandic spikes increase impulsivity in ADHD - a neuropsychological pilot study
    Martin Holtmann
    Department of Child and Adolescent Psychiatry and Psychotherapy, J W Goethe University, Frankfurt Main, Germany
    Brain Dev 28:633-40. 2006
    ....
  17. doi request reprint Nicotine and alcohol use in adolescent psychiatric inpatients: associations with diagnoses, psychosocial factors, gender and age
    Susan N Ribeiro
    Central Institute of Mental Health, Department of Child and Adolescent Psychiatry, Mannheim, Germany
    Nord J Psychiatry 62:315-21. 2008
    ..Furthermore, regular alcohol use in both girls and boys was associated with nicotine use. To conclude, early initiation and elevated rates of nicotine and alcohol use are a particular risk for adolescents with CD and ADHD...
  18. doi request reprint [Bipolar disorders as co-morbidity in childhood and adolescence--underdiagnosed or overinterpreted? Therapy of a 14-year-old boy with hyperkinetic conduct disorder and hypomania]
    Boris Rothermel
    Klinik für Psychiatrie und Psychotherapie des Kindes und Jugendalters am Zentralinstitut für Seelische Gesundheit, Mannheim
    Z Kinder Jugendpsychiatr Psychother 38:123-9; quiz 130. 2010
    ..Considerable debate exists regarding differing prevalence rates of co-morbid bipolar disorder in children and adolescents with ADHD in Germany as compared to the US...
  19. ncbi request reprint Interaction between the dopamine D4 receptor and the serotonin transporter promoter polymorphisms in alcohol and tobacco use among 15-year-olds
    M H Skowronek
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, P O Box 12 21 20, 68072, Mannheim, Germany
    Neurogenetics 7:239-46. 2006
    ..The genetic and potential molecular background underlying adolescent vulnerability to substance abuse is discussed...
  20. ncbi request reprint Association of the DRD4 exon III polymorphism with smoking in fifteen-year-olds: a mediating role for novelty seeking?
    Manfred Laucht
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, D 68072 Mannheim, Germany
    J Am Acad Child Adolesc Psychiatry 44:477-84. 2005
    ....
  21. pmc Molecular genetics of attention-deficit/hyperactivity disorder: an overview
    Tobias Banaschewski
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    Eur Child Adolesc Psychiatry 19:237-57. 2010
    ....
  22. ncbi request reprint [Methylphenidate of retard forms in children and adolescents with ADHD - an overview]
    R Pelz
    Klinik für Psychiatrie und Psychotherapie des Kindes und Jugendalters am Zentralinstitut für Seelische Gesundheit, Mannheim
    Klin Padiatr 220:93-100. 2008
    ..A more precise adaptation to the daily obligations and needs of children and adolescents is needed. Possibly, a combination with unretareded MPH might lead to a better effect/side-effect profile...
  23. ncbi request reprint ["Body and soul and friendships destroyed". Behavior therapy of a 14-year-old adolescent with alcohol dependence syndrome]
    K Becker
    Klinik für Psychiatrie und Psychotherapie des Kindes und Jugendalters am Zentralinstitut für Seelische Gesundheit, Postfach 12 21 20, 68072 Mannheim
    Z Kinder Jugendpsychiatr Psychother 31:145-53. 2003
    ..Whereas adults who abuse alcohol benefit from a variety of therapy manuals and numerous institutions offering long-term disorder-specific care, the situation with regard to adolescent patients needs to be upgraded...
  24. ncbi request reprint Are regulatory problems in infancy precursors of later hyperkinetic symptoms?
    K Becker
    Central Institute of Mental Health, Department of Child and Adolescent Psychiatry and Psychotherapy, Mannheim, Germany
    Acta Paediatr 93:1463-9. 2004
    ..To examine whether regulatory problems in infancy predict later hyperkinetic symptoms in childhood and pre-adolescence...
  25. ncbi request reprint The dopamine D4 receptor gene exon III polymorphism is associated with novelty seeking in 15-year-old males from a high-risk community sample
    K Becker
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    J Neural Transm 112:847-58. 2005
    ..In females no association with temperament was observed. This association could not be explained by the presence of either an attention-deficit/hyperactivity disorder (ADHD) or a DRD4 by ADHD interaction...
  26. ncbi request reprint [Comorbidity of compulsive disorders in childhood and adolescence]
    K Becker
    Klinik für Psychiatrie und Psychotherapie des Kindes und Jugendalters am Zentralinstitut für Seelische Gesundheit, Mannheim
    Z Kinder Jugendpsychiatr Psychother 31:175-85. 2003
    ..The cross-sectional comorbidity of child and adolescent inpatients with obsessive-compulsive disorder (OCD) was assessed...
  27. ncbi request reprint [Methylphenidate double-blind trial: indication and performing]
    L Bliznakova
    Klinik für Psychiatrie und Psychotherapie des Kindes und Jugendalters am Zentralinstitut für Seelische Gesundheit, Mannheim, Germany
    Klin Padiatr 219:9-16. 2007
    ..Further it is helpful in verifying potential undesirable side effects and improving patients' compliance...
  28. ncbi request reprint Association between ADHD and smoking in adolescence: shared genetic, environmental and psychopathological factors
    M Laucht
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    J Neural Transm 114:1097-104. 2007
    ..These findings suggest that the association of ADHD with smoking relies on risk factors shared by the two behaviors...
  29. ncbi request reprint Parasuicide online: Can suicide websites trigger suicidal behaviour in predisposed adolescents?
    K Becker
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannhein, Germany
    Nord J Psychiatry 58:111-4. 2004
    ..The application of media guidelines for suicide prevention is demanded for websites, as are accessible self-help sites for suicidal persons targeted to youthful users...
  30. ncbi request reprint Increased frequency of rolandic spikes in ADHD children
    Martin Holtmann
    Central Institute of Mental Health, Department of Child and Adolescent Psychiatry and Psychotherapy, Mannheim, Germany
    Epilepsia 44:1241-4. 2003
    ..ADHD patients with and without discharges are compared regarding age at admission, sex, global functioning, and distribution of ADHD subtypes...
  31. doi request reprint Categorical and dimensional structure of autism spectrum disorders: the nosologic validity of Asperger Syndrome
    Inge Kamp-Becker
    Department of Child and Adolescent Psychiatry and Psychotherapy, Philipps University Marburg, Hans Sachs Strasse 6, Marburg, Germany
    J Autism Dev Disord 40:921-9. 2010
    ..On the contrary, it provides evidence that e.g. AS and autism are not qualitatively distinct disorders, but rather different quantitative manifestations of the same disorder...
  32. ncbi request reprint Attention deficits and subclinical epileptiform discharges: are EEG diagnostics in ADHD optional or essential?
    Katja Becker
    Dev Med Child Neurol 46:431-2. 2004
  33. ncbi request reprint 'Attention deficits and subclinical epileptiform discharges: are EEG diagnostics in ADHD optional or essential?'
    Katja Becker
    Dev Med Child Neurol 46:501-2. 2004
  34. ncbi request reprint A prospective, multicenter, open-label assessment of atomoxetine in non-North American children and adolescents with ADHD
    Jan K Buitelaar
    Department of Psychiatry, University Medical Center Nijmegen, 9101, 6500, HB Nijmegen, The Netherlands
    Eur Child Adolesc Psychiatry 13:249-57. 2004
    ..The aim of this study was to study treatment response to atomoxetine in a large, multicenter study of non-North American patients with ADHD...
  35. ncbi request reprint ["Who belongs to your family"]
    Katja Becker
    Prax Kinderpsychol Kinderpsychiatr 54:711-3. 2005
  36. ncbi request reprint Molecular basis of glutathione reductase deficiency in human blood cells
    Nanne M Kamerbeek
    Sanquin Research and Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Plesmanlaan 125, 1066 CX Amsterdam, The Netherlands
    Blood 109:3560-6. 2007
    ..Studies on recombinant GR G330A revealed a drastically impaired thermostability of the protein. This is the first identification of mutations in the GR gene causing clinical GR deficiency...
  37. ncbi request reprint Exposure to neonatal separation stress alters exploratory behavior and corticotropin releasing factor expression in neurons in the amygdala and hippocampus
    Katja Becker
    Department of Zoology Developmental Neurobiology, Institute of Biology, Otto von Guericke University, 39118 Magdeburg, Germany
    Dev Neurobiol 67:617-29. 2007
    ..Additional behavioral analysis revealed significantly elevated exploratory behavior (+34%) in stressed animals compared to controls, which might indicate reduced anxiety in the stressed animals...