U Cassens

Summary

Country: Germany

Publications

  1. ncbi request reprint Factors affecting the efficacy of peripheral blood progenitor cells collections by large-volume leukaphereses with standardized processing volumes
    Uwe Cassens
    Institute of Transfusion Medicine, Department of Medical Informatics and Biomathematics, University Hospital Munster, Germany
    Transfusion 44:1593-602. 2004
  2. ncbi request reprint Simplified volumetric flow cytometry allows feasible and accurate determination of CD4 T lymphocytes in immunodeficient patients worldwide
    Uwe Cassens
    Institute of Transfusion Medicine, University Hospital Munster, Germany
    Antivir Ther 9:395-405. 2004
  3. ncbi request reprint Processing of peripheral blood progenitor cell components in improved clean areas does not reduce the rate of microbial contamination
    Uwe Cassens
    Department of Transfusion Medicine Transplantation Immunology, University Hospital Munster, Germany
    Transfusion 42:10-7. 2002
  4. ncbi request reprint A novel true volumetric method for the determination of residual leucocytes in blood components
    U Cassens
    Institute for Transfusion Medicine Department for Transplantation Immunology, University Hospital Munster, Germany
    Vox Sang 82:198-206. 2002
  5. ncbi request reprint Circulatory arrest during PBPC apheresis in an unrelated donor
    Uwe Cassens
    Institute of Transfusion Medicine Department of Transplantation Immunology, University Hospital Muenster, Muenster, Germany
    Transfusion 43:736-41. 2003
  6. ncbi request reprint Kinetics of standardized large volume leukapheresis (LVL) in patients do not show a recruitment phenomenon of peripheral blood progenitor cells (PBPC)
    U Cassens
    Department of Transfusion Medicine/Transplantation Immunology, University Hospital Muenster, Muenster, Germany
    Bone Marrow Transplant 28:13-20. 2001
  7. doi request reprint The isotype of autoantibodies influences the phagocytosis of antibody-coated platelets in autoimmune thrombocytopenic purpura
    M Hoemberg
    Institute of Transfusion Medicine and Transplantation Immunology, University Hospital Muenster, Germany
    Scand J Immunol 74:489-95. 2011
  8. ncbi request reprint Quantification of PCR products using microparticles and flow cytometry
    N Wedemeyer
    Institut fur Strahlenbiologie, Westfalische Wilhelms Universitat Munster, Robert Koch Str 43, 48149 Munster, Germany
    Ann Biol Clin (Paris) 62:65-71. 2004
  9. ncbi request reprint Strategies to reduce perioperative blood loss related to non-surgical bleeding
    A Menzebach
    University Hospital Muenster, Department of Anaesthesiology and Intensive Care, Muenster, Germany
    Eur J Anaesthesiol 20:764-70. 2003
  10. ncbi request reprint Polymorphisms in the non-coding region of the human mitochondrial genome in unrelated plateletapheresis donors
    H S Garritsen
    Department of Transfusion Medicine and Transplantation Immunology, Tissue Typing Laboratory, University Hospital Munster, Domagkstr 11, 48149 Germany
    Br J Haematol 112:995-1003. 2001

Collaborators

Detail Information

Publications22

  1. ncbi request reprint Factors affecting the efficacy of peripheral blood progenitor cells collections by large-volume leukaphereses with standardized processing volumes
    Uwe Cassens
    Institute of Transfusion Medicine, Department of Medical Informatics and Biomathematics, University Hospital Munster, Germany
    Transfusion 44:1593-602. 2004
    ..Peripheral blood progenitor cell (PBPC) collections should be safe and efficient. Therefore, the influence and risk factors in large-volume leukaphereses (LVL) with standardized blood volumes was investigated...
  2. ncbi request reprint Simplified volumetric flow cytometry allows feasible and accurate determination of CD4 T lymphocytes in immunodeficient patients worldwide
    Uwe Cassens
    Institute of Transfusion Medicine, University Hospital Munster, Germany
    Antivir Ther 9:395-405. 2004
    ..2%. The low-cost device and the simplified no-lyse, no-wash test procedure reduces the costs per determination and facilitates the use of flow cytometry in developing countries...
  3. ncbi request reprint Processing of peripheral blood progenitor cell components in improved clean areas does not reduce the rate of microbial contamination
    Uwe Cassens
    Department of Transfusion Medicine Transplantation Immunology, University Hospital Munster, Germany
    Transfusion 42:10-7. 2002
    ..Therefore, principles of Good Manufacturing Practice (GMP) are applicable for processing of PBPC components to reduce potential risks of contamination...
  4. ncbi request reprint A novel true volumetric method for the determination of residual leucocytes in blood components
    U Cassens
    Institute for Transfusion Medicine Department for Transplantation Immunology, University Hospital Munster, Germany
    Vox Sang 82:198-206. 2002
    ..Accurate determination of residual leucocytes [white blood cells (WBC)] in blood components is of high clinical importance. To date, several labour-intensive, time-consuming or expensive techniques have been used for this purpose...
  5. ncbi request reprint Circulatory arrest during PBPC apheresis in an unrelated donor
    Uwe Cassens
    Institute of Transfusion Medicine Department of Transplantation Immunology, University Hospital Muenster, Muenster, Germany
    Transfusion 43:736-41. 2003
    ..Nowadays, the collection of PBPCs by apheresis from healthy donors is a routine method. The mobilization with rHu G-CSF and the apheresis procedures are usually well tolerated without severe side effects...
  6. ncbi request reprint Kinetics of standardized large volume leukapheresis (LVL) in patients do not show a recruitment phenomenon of peripheral blood progenitor cells (PBPC)
    U Cassens
    Department of Transfusion Medicine/Transplantation Immunology, University Hospital Muenster, Muenster, Germany
    Bone Marrow Transplant 28:13-20. 2001
    ..In summary, a recruitment phenomenon, defined as a time-dependent and LVL-induced increase of PBPC, could not be demonstrated in any of the diseases investigated...
  7. doi request reprint The isotype of autoantibodies influences the phagocytosis of antibody-coated platelets in autoimmune thrombocytopenic purpura
    M Hoemberg
    Institute of Transfusion Medicine and Transplantation Immunology, University Hospital Muenster, Germany
    Scand J Immunol 74:489-95. 2011
    ..Therefore, the AITP-mediating autoantibody isotype should be considered more carefully in pathophysiologic models and furthermore in diagnostic, therapeutic and prognostic approaches in AITP...
  8. ncbi request reprint Quantification of PCR products using microparticles and flow cytometry
    N Wedemeyer
    Institut fur Strahlenbiologie, Westfalische Wilhelms Universitat Munster, Robert Koch Str 43, 48149 Munster, Germany
    Ann Biol Clin (Paris) 62:65-71. 2004
    ..We conclude that the analysis of PCR products using microparticles and flow cytometry fulfils the criteria of clinical routine diagnostics regarding (i) sensitivity, (ii) specificity, (iii) reproducibility and (iv) automatibility...
  9. ncbi request reprint Strategies to reduce perioperative blood loss related to non-surgical bleeding
    A Menzebach
    University Hospital Muenster, Department of Anaesthesiology and Intensive Care, Muenster, Germany
    Eur J Anaesthesiol 20:764-70. 2003
    ..If this can positively be excluded and if all of measures described fail to reduce or stop the bleeding, further treatment of such uncontrolled bleeding remains symptomatic...
  10. ncbi request reprint Polymorphisms in the non-coding region of the human mitochondrial genome in unrelated plateletapheresis donors
    H S Garritsen
    Department of Transfusion Medicine and Transplantation Immunology, Tissue Typing Laboratory, University Hospital Munster, Domagkstr 11, 48149 Germany
    Br J Haematol 112:995-1003. 2001
    ....
  11. ncbi request reprint Automated serological compatibility testing using a solid-phase test and standard laboratory equipment
    N Ostendorf
    Department of Transfusion Medicine and Transplantation Immunology, Westfaelische Wilhelms Universitaet, Munster, Germany
    Vox Sang 80:225-9. 2001
    ..To prove the feasibility of a semi-automated cross-match procedure using a commercially available solid-phase microplate test and standard laboratory equipment...
  12. ncbi request reprint Platelet glycoprotein complex Ia/IIa antibodies cause neonatal alloimmune thrombocytopenia but do not inhibit megakaryopoiesis and platelet recovery after allogeneic cord blood stem cell transplantation
    U Cassens
    Department of Transfusion Medicine/Transplantation Immunology, University Hospital Muenster, Muenster, Germany
    Bone Marrow Transplant 28:803-6. 2001
    ..This case demonstrates a successful CB transplantation from a donor suffering from NAIT...
  13. ncbi request reprint The impact of erythrocyte lysing procedures on the recovery of hematopoietic progenitor cells in flow cytometric analysis
    Burkhard Greve
    Department of Radiobiology, University Hospital Munster, Robert Koch Strasse 43, D 48149 Munster, Germany
    Stem Cells 24:793-9. 2006
    ..As demonstrated by the high accuracy of the 1-PF technique, all erythrocyte lysing procedures caused significant cell loss, which led to inconsistent counting of CD34+ cells in nonvolumetric flow cytometric (2-PF) protocols...
  14. ncbi request reprint Evidence that human autoimmune thrombocytopenia mediated by both immunoglobulin isotypes IgM and IgG is an independent disease entity
    Dorothea Stahl
    University of Munster, Institute for Transfusion Medicine, Domagkstrasse 11, D 48149 Munster, Germany
    Eur J Haematol 75:318-27. 2005
    ..The role of autoantibody isotype for the pathophysiology of AITP might currently be underestimated, and diagnostic and therapeutic procedures in AITP might profit from considering autoantibody isotype more carefully...
  15. ncbi request reprint Influence of isotypes of disease-associated autoantibodies on the expression of natural autoantibody repertoires in humans
    Dorothea Stahl
    University of Munster, Institute for Transfusion Medicine, Domagkstrasse 11, 48149 Munster, Germany
    Immunol Lett 102:50-9. 2006
    ....
  16. ncbi request reprint High-grade loss of leukocytes and hematopoietic progenitor cells caused by erythrocyte-lysing procedures for flow cytometric analyses
    Burkhard Greve
    Department of Radiobiology, University Hospital Munster, 48149 Munster, Germany
    J Hematother Stem Cell Res 12:321-30. 2003
    ....
  17. ncbi request reprint Semiquantitative measurement of IgG subclasses and IgM of platelet-specific antibodies in a glycoprotein-specific platelet-antigen capture assay
    Reinhard Kelsch
    Department of Transfusion Medicine, University Hospital Munster, Germany
    Br J Haematol 117:141-50. 2002
    ..The PAC assay sensitively detects the subclasses of platelet-specific IgG and human leucocyte antigen (HLA)-antibodies independently. It is easy to perform and takes less time than other platelet glycoprotein-specific methods...
  18. ncbi request reprint Cryopreservation reduces the concentration of detectable bacteria in contaminated peripheral blood progenitor cell products
    Frank Kipp
    Institute of Medical Microbiology, the Institute of Transfusion Medicine Transplantation Immunology, and the Department of Biometrics, University Hospital Munster, Germany
    Transfusion 44:1098-103. 2004
    ..Microbial contamination of PBPC products PBPCPs may cause severe clinical complications. There-fore, we investigated the influence of cryopreservation on the sensitivity to detect bacterial contaminations in PBPCPs...
  19. ncbi request reprint The influence of blood group differences in allogeneic hematopoietic peripheral blood progenitor cell transplantation
    Christian G Erker
    Institute for Transfusion Medicine, University Hospital of Muenster, Muenster, Germany
    Transfusion 45:1382-90. 2005
    ..Although several studies have addressed this issue, the clinical influence of blood group differences on transfusion requirements and survival is still discussed controversially, especially in the case of PBPCT...
  20. ncbi request reprint A noninvasive strategy for screening prospective blood donors for anemia
    Ramin Lotfi
    Department of Transfusion Medicine, Eberhard Karls University, Tuebingen, Germany
    Transfusion 45:1585-92. 2005
    ..The reliability of capillary hemoglobin (Hb) as an indicator for eligibility to donate blood is discussed controversially. Therefore, a noninvasive alternative with acceptable predictive values was established and evaluated...
  21. ncbi request reprint The role of caspases in cryoinjury: caspase inhibition strongly improves the recovery of cryopreserved hematopoietic and other cells
    Christopher Stroh
    Institute of Experimental Dermatology, University of Munster, D 48149 Munster, Germany
    FASEB J 16:1651-3. 2002
    ..The addition of caspase inhibitors may be an important tool for the cryopreservation of living cells and advantageous in cell transplantation, tissue engineering, and other genetic technologies...
  22. ncbi request reprint Different activation patterns of proinflammatory cytokines in melancholic and non-melancholic major depression are associated with HPA axis activity
    Florian Kaestner
    Department of Psychiatry, University of Muenster, Albert Schweitzer Strasse 11, D 48149 Muenster, Germany
    J Affect Disord 87:305-11. 2005
    ....