Martin Canis

Summary

Country: Germany

Publications

  1. pmc Betahistine exerts a dose-dependent effect on cochlear stria vascularis blood flow in guinea pigs in vivo
    Fritz Ihler
    Department of Otorhinolaryngology, Head and Neck Surgery, Goettingen University Medical School, Gottingen, Germany
    PLoS ONE 7:e39086. 2012
  2. ncbi request reprint [CT-assisted navigation for retrosigmoidal implantation of the Bonebridge]
    M Canis
    Klinik und Poliklinik für Hals Nasen Ohrenheilkunde, Universitatsmedizin Gottingen, Robert Koch Str 40, 37099, Gottingen, Deutschland
    HNO 61:1038-44. 2013
  3. pmc Organ preservation in T4a laryngeal cancer: is transoral laser microsurgery an option?
    Martin Canis
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Gottingen, Robert Koch Str 40, 37099 Gottingen, Germany
    Eur Arch Otorhinolaryngol 270:2719-27. 2013
  4. pmc Results of transoral laser microsurgery for supraglottic carcinoma in 277 patients
    Martin Canis
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Gottingen, Robert Koch Str 40, 37099 Gottingen, Germany
    Eur Arch Otorhinolaryngol 270:2315-26. 2013
  5. pmc Results of transoral laser microsurgery in 102 patients with squamous cell carcinoma of the tonsil
    Martin Canis
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Gottingen, Robert Koch Str 40, 37099 Gottingen, Germany
    Eur Arch Otorhinolaryngol 270:2299-306. 2013
  6. doi request reprint CD133 is a predictor of poor survival in head and neck squamous cell carcinomas
    Martin Canis
    Department of Otorhinolaryngology, Head and Neck Surgery, Grosshadern Medical Center, Ludwig Maximilians University of Munich, Munich, Germany
    Cancer Biomark 12:97-105. 2012
  7. pmc CD133 induces tumour-initiating properties in HEK293 cells
    Martin Canis
    Department of Otorhinolaryngology, Head and Neck Surgery, Grosshadern Medical Centre, Ludwig Maximilians University of Munich, Marchioninistr 15, 81377, Munich, Germany
    Tumour Biol 34:437-43. 2013
  8. ncbi request reprint Oncologic and functional results after transoral laser microsurgery of tongue base carcinoma
    Martin Canis
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Goettingen, Robert Koch Str 40, 37075, Goettingen, Germany
    Eur Arch Otorhinolaryngol 270:1075-83. 2013
  9. doi request reprint Impact of elective neck dissection vs observation on regional recurrence and survival in cN0-staged patients with squamous cell carcinomas of the upper aerodigestive tract
    Martin Canis
    Department of Otorhinolaryngology Head and Neck Surgery, University of Gottingen, Germany
    Arch Otolaryngol Head Neck Surg 138:650-5. 2012
  10. doi request reprint IgE reactivity patterns in patients with allergic rhinoconjunctivitis to ragweed and mugwort pollens
    Martin Canis
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Goettingen, Robert Koch Strasse 40, Goettingen, Germany
    Am J Rhinol Allergy 26:31-5. 2012

Collaborators

Detail Information

Publications31

  1. pmc Betahistine exerts a dose-dependent effect on cochlear stria vascularis blood flow in guinea pigs in vivo
    Fritz Ihler
    Department of Otorhinolaryngology, Head and Neck Surgery, Goettingen University Medical School, Gottingen, Germany
    PLoS ONE 7:e39086. 2012
    ..This study investigated the effect of betahistine on guinea pigs at dosages corresponding to clinically used doses for cochlear microcirculation...
  2. ncbi request reprint [CT-assisted navigation for retrosigmoidal implantation of the Bonebridge]
    M Canis
    Klinik und Poliklinik für Hals Nasen Ohrenheilkunde, Universitatsmedizin Gottingen, Robert Koch Str 40, 37099, Gottingen, Deutschland
    HNO 61:1038-44. 2013
    ..We thus report on two patients in whom the Bonebridge was implanted via a retrosigmoid approach using CT-guided navigation. ..
  3. pmc Organ preservation in T4a laryngeal cancer: is transoral laser microsurgery an option?
    Martin Canis
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Gottingen, Robert Koch Str 40, 37099 Gottingen, Germany
    Eur Arch Otorhinolaryngol 270:2719-27. 2013
    ..TLM results in a low morbidity, rapid recovery and good function and can be a valid option for organ preserving surgery of pT4a glottic and supraglottic cancer...
  4. pmc Results of transoral laser microsurgery for supraglottic carcinoma in 277 patients
    Martin Canis
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Gottingen, Robert Koch Str 40, 37099 Gottingen, Germany
    Eur Arch Otorhinolaryngol 270:2315-26. 2013
    ..Transoral laser microsurgery results in a low morbidity, rapid recovery, and superior function compared with standard therapy...
  5. pmc Results of transoral laser microsurgery in 102 patients with squamous cell carcinoma of the tonsil
    Martin Canis
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Gottingen, Robert Koch Str 40, 37099 Gottingen, Germany
    Eur Arch Otorhinolaryngol 270:2299-306. 2013
    ..The oncological and functional results are comparable to any other treatment regimen, while the morbidity and complications tend to be lower...
  6. doi request reprint CD133 is a predictor of poor survival in head and neck squamous cell carcinomas
    Martin Canis
    Department of Otorhinolaryngology, Head and Neck Surgery, Grosshadern Medical Center, Ludwig Maximilians University of Munich, Munich, Germany
    Cancer Biomark 12:97-105. 2012
    ..The pentaspan protein CD133 (Prominin-1) is a predictive marker and part of the signature of tumour-initiating cells (TICs) for various cancer entities...
  7. pmc CD133 induces tumour-initiating properties in HEK293 cells
    Martin Canis
    Department of Otorhinolaryngology, Head and Neck Surgery, Grosshadern Medical Centre, Ludwig Maximilians University of Munich, Marchioninistr 15, 81377, Munich, Germany
    Tumour Biol 34:437-43. 2013
    ..CD133 induces tumour-initiating properties in HEK293 cells in vivo and is potentially involved in the regulation of tumourigenicity. Future research will aim at the elucidation of molecular mechanisms of CD133-induced tumourigenicity...
  8. ncbi request reprint Oncologic and functional results after transoral laser microsurgery of tongue base carcinoma
    Martin Canis
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Goettingen, Robert Koch Str 40, 37075, Goettingen, Germany
    Eur Arch Otorhinolaryngol 270:1075-83. 2013
    ..Primary transoral laser microsurgery of tongue base carcinoma offers convincing oncological and functional results comparable to other treatment modalities, e.g., radio(chemo)therapy but has lower rates of morbidity...
  9. doi request reprint Impact of elective neck dissection vs observation on regional recurrence and survival in cN0-staged patients with squamous cell carcinomas of the upper aerodigestive tract
    Martin Canis
    Department of Otorhinolaryngology Head and Neck Surgery, University of Gottingen, Germany
    Arch Otolaryngol Head Neck Surg 138:650-5. 2012
    ..To evaluate the impact of elective selective neck dissection vs observation on regional recurrence and survival in cN0-staged patients after transoral microscopic laser surgery of squamous cell carcinomas of the upper aerodigestive tract...
  10. doi request reprint IgE reactivity patterns in patients with allergic rhinoconjunctivitis to ragweed and mugwort pollens
    Martin Canis
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Goettingen, Robert Koch Strasse 40, Goettingen, Germany
    Am J Rhinol Allergy 26:31-5. 2012
    ..Results were correlated to clinical findings such as medical history and health-related quality of life (HRQL)...
  11. doi request reprint Recombinant marker allergens in diagnosis of patients with allergic rhinoconjunctivitis to tree and grass pollens
    Martin Canis
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Munich, Munich, Germany
    Am J Rhinol Allergy 25:36-9. 2011
    ..The aim of this study was to investigate recombinant marker allergens in patients with allergic rhinoconjunctivitis to tree and grass pollens...
  12. doi request reprint Modeling the measurements of cochlear microcirculation and hearing function after loud noise
    Warangkana Arpornchayanon
    Walter Brendel Center for Experimental Medicine, University of Munich, Munich, Germany
    Otolaryngol Head Neck Surg 145:463-9. 2011
    ..The aim of this study was to establish an animal model for in vivo analysis of cochlear microcirculation and hearing function after a loud noise to allow precise measurements of both parameters in vivo...
  13. doi request reprint Quantitative estimation of minor conductive hearing loss with distortion product otoacoustic emissions in the guinea pig
    Bernhard Olzowy
    Department of Otorhinolaryngology, Head and Neck Surgery, Ludwig Maximilians University of Munich Medical Center, Marchioninistr 15, 81377 Munich, Germany
    J Acoust Soc Am 128:1845-52. 2010
    ..CHL(DPOAE) correlated well with CHL(CAP) (R=0.741, p=0.0142). Mean difference between CHL(DPOAE) and CHL(CAP) was 4.2±2.6 dB. Estimation of minor CHL from DPOAE measurements might help to increase the diagnostic value of DPOAEs...
  14. ncbi request reprint Level alterations of the 2f (1)-f (2) distortion product due to hypoxia in the guinea pig depend on the stimulus frequency
    Bernhard Olzowy
    Department of Otorhinolaryngology, Head and Neck Surgery, Ludwig Maximilians University of Munich Medical Center, Marchioninistr 15, 81377 Munchen, Germany
    Eur Arch Otorhinolaryngol 267:351-5. 2010
    ..16 kHz). DPOAE level alterations due to hypoxia depend on the frequency in guinea pigs. Studies in human are warranted to improve non-invasive ICP monitoring with DPOAE by the detection of hypoxia-related changes...
  15. doi request reprint Mediators and cytokines in persistent allergic rhinitis and nonallergic rhinitis with eosinophilia syndrome
    Moritz Gröger
    Department of Oto Rhino Laryngology, Head and Neck Surgery, Munich, Germany
    Int Arch Allergy Immunol 159:171-8. 2012
    ..Patients with nonallergic rhinitis with eosinophilia syndrome (NARES) show typical symptoms of persistent allergic rhinitis (PAR). The aim of the present study was to compare nasal cytokine patterns between NARES and PAR...
  16. ncbi request reprint Transoral laser microsurgery in treatment of pT2 and pT3 glottic laryngeal squamous cell carcinoma - results of 391 patients
    Martin Canis
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Gottingen, Germany
    Head Neck 36:859-66. 2014
    ..The purpose of this study was to evaluate oncological and functional results of transoral laser microsurgery (TLM) in patients with T2 and T3 glottic laryngeal squamous cell carcinoma (SCC)...
  17. doi request reprint Recombinant allergen profiles and health-related quality of life in seasonal allergic rhinitis
    Martin Canis
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Munich, Germany
    Allergy Asthma Proc 31:219-26. 2010
    ..Monosensitized patients showed IgE against major allergens in 100% of cases. Patients sensitized solely against major or minor allergens showed no differences in HRQL...
  18. doi request reprint Acute hyperfibrinogenemia impairs cochlear blood flow and hearing function in guinea pigs in vivo
    Fritz Ihler
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Göttingen Hospital, Robert Koch Strasse 40, Gottingen, Germany
    Int J Audiol 51:210-5. 2012
    ..Fibrinogen is known as a risk factor for both microvascular dysfunction and SSNHL. Therefore, the aim of this study was to investigate the effect of elevated serum levels of fibrinogen on cochlear blood flow and hearing function in vivo...
  19. ncbi request reprint Enoral laser microsurgery for squamous cell carcinoma of the oral cavity
    Martin Canis
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Gottingen, Germany
    Head Neck 36:787-94. 2014
    ..The purpose of this study was to investigate oncological and functional results of enoral laser microsurgery in treatment for cancer of the oral cavity...
  20. ncbi request reprint Results of 226 patients with T3 laryngeal carcinoma after treatment with transoral laser microsurgery
    Martin Canis
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Gottingen, Germany
    Head Neck 36:652-9. 2014
    ..The purpose of this study was to assess the feasibility of transoral laser microsurgery (TLM) in treatment of pT3 laryngeal cancer...
  21. pmc Tumor necrosis factor-α enhances microvascular tone and reduces blood flow in the cochlea via enhanced sphingosine-1-phosphate signaling
    Elias Q Scherer
    Hals Nasen Ohrenklinik und Poliklinik, Klinikum rechts der Isar der Technischen Universitat Munchen, Munich, Germany
    Stroke 41:2618-24. 2010
    ..We sought to demonstrate that tumor necrosis factor (TNF)-α, via sphingosine-1-phosphate signaling, has the potential to alter cochlear blood flow and thus, cause ischemic hearing loss...
  22. doi request reprint Free flap salvage with subcutaneous injection of tissue plasminogen activator in head and neck patients
    Friedrich Ihler
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Gottingen, Germany
    Microsurgery 33:478-81. 2013
    ..We therefore suggest subcutaneous rt-PA injection as an additional tool in managing difficult and recurrent cases of venous thrombosis in free flap head and neck reconstruction...
  23. doi request reprint An animal model for the analysis of cochlear blood flow [corrected] disturbance and hearing threshold in vivo
    Martin Canis
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Munich LMU, Campus Grosshadern, Munich, Germany
    Eur Arch Otorhinolaryngol 267:197-203. 2010
    ..This technique can be used to evaluate effects of treatments aimed at cochlear microcirculation in inner ear pathologies...
  24. doi request reprint Tropomyosin sensitization in house dust mite allergic patients
    Sven Becker
    Department of Otorhinolaryngology Head and Neck Surgery, Ludwig Maximilian University, Marchioninistrasse 15, 81377 Munich, Germany
    Eur Arch Otorhinolaryngol 269:1291-6. 2012
    ..Beside the direct allergic reactions, a further part of reactions to seafood must therefore be ascribed to other mechanisms such as intoxication or intolerance to, e.g. additives in the food product...
  25. ncbi request reprint Automated assessment of tumour microvascular architecture in vivo
    Sven Becker
    Department of Otorhinolaryngology, Head and Neck Surgery, Ludwig Maximilians University, Marchioninistrasse 15, D 81377 Munich, Germany
    Anticancer Res 30:2597-602. 2010
    ..The aim of this study was to develop an automated analysis technique enabling quantitative assessment of complete tumour vascular networks non-invasively in vivo...
  26. doi request reprint Olfactory dysfunction in seasonal and perennial allergic rhinitis
    Sven Becker
    Department of Otorhinolaryngology Head and Neck Surgery, Ludwig Maximilians University Munich, Germany
    Acta Otolaryngol 132:763-8. 2012
    ..Therefore, the decrease in olfactory functions seems to be predominantly caused by the inflammation of the epithelium and not by the obstruction of the nose caused by the inflammation...
  27. doi request reprint Coated collagen patches for closure of pharyngo-cutaneous fistulas
    Bernhard G Weiss
    Department of Otolaryngology, Head and Neck Surgery, University of Gottingen
    Am J Otolaryngol 35:246-50. 2014
    ..After occurrence of a fistula the healing process is intended to be accelerated by primary closure with TachoSil(®) or by sealing of a primary suture. ..
  28. doi request reprint Nuclear signalling by tumour-associated antigen EpCAM
    Dorothea Maetzel
    Clinical Cooperation Group Molecular Oncology, Helmholtz Zentrum Munchen, German Research Center for Environmental Health, and Head and Neck Research Dept, Ludwig Maximilians University of Munich, Germany
    Nat Cell Biol 11:162-71. 2009
    ..In patients, EpICD was found in nuclei of colon carcinoma but not of normal tissue. Nuclear signalling of EpCAM explains how EpCAM functions in cell proliferation...
  29. pmc Fibrinogen/LDL apheresis is a promising rescue therapy for sudden sensorineural hearing loss
    Martin Canis
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Goettingen, Goettingen, Germany
    Clin Res Cardiol Suppl 7:36-40. 2012
    ..This study is aimed to investigate if reduction of fibrinogen and serum LDL is also effective in patients with SSNH non-responding toward treatment with corticosteroids and plasmaexpanders...
  30. doi request reprint Simvastatin and Ginkgo biloba in the treatment of subacute tinnitus: a retrospective study of 94 patients
    Martin Canis
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Munich, Munchen, Germany
    Am J Otolaryngol 32:19-23. 2011
    ..Studies suggest that hypercholesterolemia promotes the development of inner ear disorders such as tinnitus. However, the underlying pathomechanisms are still not clearly defined...
  31. doi request reprint Complex level alterations of the 2f (1)-f (2) distortion product due to hypoxia in the guinea pig
    Bernhard Olzowy
    Department of Otorhinolaryngology, Head and Neck Surgery, Ludwig Maximilians Universitiy of Munich Medical Center, Marchioninistr 15, 81377, Munich, Germany
    Eur Arch Otorhinolaryngol 265:1329-33. 2008
    ..A micromechanical mechanism that might explain a transient level increase and the post-hypoxic DPOAE level changes is discussed...