Stephan J Ott

Summary

Affiliation: Campus Kiel
Country: Germany

Publications

  1. pmc Effects of β-lactam antibiotics and fluoroquinolones on human gut microbiota in relation to Clostridium difficile associated diarrhea
    Henrik Knecht
    Institute of Clinical Molecular Biology IKMB, Christian Albrechts University CAU, Kiel, Germany
    PLoS ONE 9:e89417. 2014
  2. pmc Effects of probiotics and antibiotics on the intestinal homeostasis in a computer controlled model of the large intestine
    Ateequr Rehman
    Department of Environmental Health Sciences, University Medical Center, Breisacher Str 115B, D 79106 Freiburg, Germany
    BMC Microbiol 12:47. 2012
  3. pmc Genetic diversity of the obligate intracellular bacterium Chlamydophila pneumoniae by genome-wide analysis of single nucleotide polymorphisms: evidence for highly clonal population structure
    Thomas Rattei
    Institute of Medical Microbiology and Hygiene, University of Lubeck, Ratzeburger Allee 160, 23538 Lubeck, Germany
    BMC Genomics 8:355. 2007
  4. doi request reprint Fungi and inflammatory bowel diseases: Alterations of composition and diversity
    Stephan J Ott
    Institute for Clinical Molecular Biology, Christian Albrechts University CAU, Kiel, Germany
    Scand J Gastroenterol 43:831-41. 2008
  5. ncbi request reprint Fungal rDNA signatures in coronary atherosclerotic plaques
    Stephan J Ott
    Institute for Clinical Molecular Biology, Christian Albrechts University Kiel CAU, Schittenhelmstr 12, 24105 Kiel, Germany
    Environ Microbiol 9:3035-45. 2007
  6. doi request reprint Intestinal TM7 bacterial phylogenies in active inflammatory bowel disease
    Tanja Kuehbacher
    1Clinic for General Internal Medicine, I Medical Department, University Hospital Schleswig Holstein UKSH, Campus Kiel, Brunswiker Str 10, D 24105 Kiel, Germany
    J Med Microbiol 57:1569-76. 2008
  7. pmc Colonic mucosa-associated microbiota is influenced by an interaction of Crohn disease and FUT2 (Secretor) genotype
    Philipp Rausch
    Institute for Experimental Medicine, Christian Albrechts University of Kiel, D 24105 Kiel, Germany
    Proc Natl Acad Sci U S A 108:19030-5. 2011
  8. doi request reprint Transcriptional activity of the dominant gut mucosal microbiota in chronic inflammatory bowel disease patients
    Ateequr Rehman
    Institute for Clinical Molecular Biology IKMB, Christian Albrechts University CAU Kiel, Schittenhelmstrasse 12, D 24105 Kiel, Germany
    J Med Microbiol 59:1114-22. 2010
  9. pmc Dynamics of the mucosa-associated flora in ulcerative colitis patients during remission and clinical relapse
    Stephan J Ott
    Institute for Clinical Molecular Biology, Christian Albrechts University Kiel, Schittenhelmstr 12, 24105 Kiel, Germany
    J Clin Microbiol 46:3510-3. 2008
  10. ncbi request reprint Detection of diverse bacterial signatures in atherosclerotic lesions of patients with coronary heart disease
    Stephan J Ott
    Institute for Clinical Molecular Biology, Department of General Internal Medicine, UKSH Campus Kiel, Kiel, Germany
    Circulation 113:929-37. 2006

Collaborators

Detail Information

Publications14

  1. pmc Effects of β-lactam antibiotics and fluoroquinolones on human gut microbiota in relation to Clostridium difficile associated diarrhea
    Henrik Knecht
    Institute of Clinical Molecular Biology IKMB, Christian Albrechts University CAU, Kiel, Germany
    PLoS ONE 9:e89417. 2014
    ..We suggest that up- and down regulation of specific bacterial species may be involved in colonization resistance against C. difficile providing a potential therapeutic approach through specific manipulation of the intestinal microbiome. ..
  2. pmc Effects of probiotics and antibiotics on the intestinal homeostasis in a computer controlled model of the large intestine
    Ateequr Rehman
    Department of Environmental Health Sciences, University Medical Center, Breisacher Str 115B, D 79106 Freiburg, Germany
    BMC Microbiol 12:47. 2012
    ..Microbial metabolites (short chain fatty acids, lactate, branched chain fatty acids, and ammonia) and the intestinal microbiota were analyzed...
  3. pmc Genetic diversity of the obligate intracellular bacterium Chlamydophila pneumoniae by genome-wide analysis of single nucleotide polymorphisms: evidence for highly clonal population structure
    Thomas Rattei
    Institute of Medical Microbiology and Hygiene, University of Lubeck, Ratzeburger Allee 160, 23538 Lubeck, Germany
    BMC Genomics 8:355. 2007
    ..Four published genomes revealed an identity of > 99 %. This remarkable finding raised questions about the existence of distinguishable genotypes in correlation with geographical and anatomical origin...
  4. doi request reprint Fungi and inflammatory bowel diseases: Alterations of composition and diversity
    Stephan J Ott
    Institute for Clinical Molecular Biology, Christian Albrechts University CAU, Kiel, Germany
    Scand J Gastroenterol 43:831-41. 2008
    ..While a reduced bacterial diversity has been reported in IBD, little is known about the fungal microbiota. The aim of this study was to carry out a systematic analysis of intestinal fungal microbiota in IBD...
  5. ncbi request reprint Fungal rDNA signatures in coronary atherosclerotic plaques
    Stephan J Ott
    Institute for Clinical Molecular Biology, Christian Albrechts University Kiel CAU, Schittenhelmstr 12, 24105 Kiel, Germany
    Environ Microbiol 9:3035-45. 2007
    ..Coronary atheromatous plaques harbour diverse and variable fungal communities suggesting a polymicrobial contribution to the chronic inflammatory aetiology...
  6. doi request reprint Intestinal TM7 bacterial phylogenies in active inflammatory bowel disease
    Tanja Kuehbacher
    1Clinic for General Internal Medicine, I Medical Department, University Hospital Schleswig Holstein UKSH, Campus Kiel, Brunswiker Str 10, D 24105 Kiel, Germany
    J Med Microbiol 57:1569-76. 2008
    ..g. as a promoter of inflammation at early stages of disease...
  7. pmc Colonic mucosa-associated microbiota is influenced by an interaction of Crohn disease and FUT2 (Secretor) genotype
    Philipp Rausch
    Institute for Experimental Medicine, Christian Albrechts University of Kiel, D 24105 Kiel, Germany
    Proc Natl Acad Sci U S A 108:19030-5. 2011
    ....
  8. doi request reprint Transcriptional activity of the dominant gut mucosal microbiota in chronic inflammatory bowel disease patients
    Ateequr Rehman
    Institute for Clinical Molecular Biology IKMB, Christian Albrechts University CAU Kiel, Schittenhelmstrasse 12, D 24105 Kiel, Germany
    J Med Microbiol 59:1114-22. 2010
    ..The transcriptional activity points to a more functional role of the intestinal mucosal microbiota and may lead to the identification of therapeutic targets in the active modulation of microbial factors...
  9. pmc Dynamics of the mucosa-associated flora in ulcerative colitis patients during remission and clinical relapse
    Stephan J Ott
    Institute for Clinical Molecular Biology, Christian Albrechts University Kiel, Schittenhelmstr 12, 24105 Kiel, Germany
    J Clin Microbiol 46:3510-3. 2008
    ..Baseline reduction, temporal instability, and decrease of bacterial richness toward relapse were observed for UC patients, whereas the MAF for controls was stable over time...
  10. ncbi request reprint Detection of diverse bacterial signatures in atherosclerotic lesions of patients with coronary heart disease
    Stephan J Ott
    Institute for Clinical Molecular Biology, Department of General Internal Medicine, UKSH Campus Kiel, Kiel, Germany
    Circulation 113:929-37. 2006
    ..This study analyzes molecular phylogenies to systematically explore the presence, frequency, and diversity of bacteria in atherosclerotic lesions in patients with CHD...
  11. pmc Role of NOD2/CARD15 in coronary heart disease
    Nour Eddine El Mokhtari
    Department of Cardiology, University Hospital Schleswig Holstein, Kiel, Germany
    BMC Genet 8:76. 2007
    ....
  12. ncbi request reprint In vitro alterations of intestinal bacterial microbiota in fecal samples during storage
    Stephan J Ott
    Department of General Internal Medicine, University Hospital Schleswig Holstein, Campus Kiel, Kiel, Germany
    Diagn Microbiol Infect Dis 50:237-45. 2004
    ..The observed alterations of fecal flora during storage point to the difficulty of the molecular analysis of the bacterial diversity and the enumeration of bacterial cells in fecal samples...
  13. doi request reprint Modified implant surfaces show different biofilm compositions under in vivo conditions
    Birte Grössner-Schreiber
    Department of Operative Dentistry and Periodontology, School of Dentistry, University of Kiel, Kiel, Germany
    Clin Oral Implants Res 20:817-26. 2009
    ..The aim of the present study was to examine the influence of zirconium nitride (ZrN) as a potential implant surface on the biofilm composition and diversity in vivo...
  14. pmc Quantification of intestinal bacterial populations by real-time PCR with a universal primer set and minor groove binder probes: a global approach to the enteric flora
    Stephan J Ott
    Department of General Internal Medicine, University Hospital Schleswig Holstein, Campus Kiel, Schittenhelmstr 12, 24105 Kiel, Germany
    J Clin Microbiol 42:2566-72. 2004
    ..No significant cross-reaction was observed. The real-time PCR assays presented may facilitate understanding of the intestinal bacterial flora through a normalized global estimation of the major contributing species...