Bertram Brenig

Summary

Country: Germany

Publications

  1. doi request reprint Molecular genetics of coat colour variations in White Galloway and White Park cattle
    B Brenig
    Institute of Veterinary Medicine, Burckhardtweg 2, D 37077, Gottingen, Germany
    Anim Genet 44:450-3. 2013
  2. pmc PrPSc spreading patterns in the brain of sheep linked to different prion types
    Wiebke M Wemheuer
    Prion and Dementia Research Unit, Department of Neuropathology, University Medical Center, Georg August University, Robert Koch Str, 40, 37075 Goettingen, Germany
    Vet Res 42:32. 2011
  3. pmc A high resolution physical and RH map of pig chromosome 6q1.2 and comparative analysis with human chromosome 19q13.1
    Flávia Martins-Wess
    Institute of Animal Breeding and Genetics, School of Veterinary Medicine Hannover, Bunteweg 17p, 30559 Hannover, Germany
    BMC Genomics 4:20. 2003
  4. pmc X- and Y-chromosome specific variants of the amelogenin gene allow sex determination in sheep (Ovis aries) and European red deer (Cervus elaphus)
    I Pfeiffer
    Department of Molecular Biology, Institute of Veterinary Medicine, Goettingen, Germany
    BMC Genet 6:16. 2005
  5. pmc Genome-wide QTL mapping for three traits related to teat number in a White Duroc x Erhualian pig resource population
    Nengshui Ding
    Key Laboratory for Animal Biotechnology of Jiangxi Province and the Ministry of Agriculture of China, Jiangxi Agricultural University, Nanchang 330045, PR China
    BMC Genet 10:6. 2009
  6. pmc A genome-wide scan for quantitative trait loci affecting limb bone lengths and areal bone mineral density of the distal femur in a White Duroc x Erhualian F2 population
    Huirong Mao
    Key Laboratory for Animal Biotechnology of Jiangxi Province and the Ministry of Agriculture of China, Jiangxi Agricultural University, Nanchang 330045, PR China
    BMC Genet 9:63. 2008
  7. ncbi request reprint Molecular cloning, mapping, and functional analysis of the bovine sulfate transporter SLC26a2 gene
    Bertram Brenig
    Institute of Veterinary Medicine, University of Gottingen, Groner Landstrasse 2, D 37073, Gottingen, Germany
    Gene 319:161-6. 2003
  8. ncbi request reprint Analysis of the 5' region of the canine PAX3 gene and exclusion as a candidate for Dalmatian deafness
    B Brenig
    Institute of Veterinary Medicine, University of Goettingen, Goettingen, Germany
    Anim Genet 34:47-50. 2003
  9. ncbi request reprint Analysis of blood clotting factor activities in canine Legg-Calvé-Perthes' disease
    B Brenig
    Institute of Veterinary Medicine, University of Gottingen, Germany
    J Vet Intern Med 13:570-3. 1999
  10. ncbi request reprint Assignment of the equine solute carrier 26A2 gene (SLC26A2) to equine chromosome 14q15-->q21 (ECA14q15-->q21) by in situ hybridization and radiation hybrid panel mapping
    B Brenig
    Institute of Veterinary Medicine, Georg August University of Gottingen, Germany
    Cytogenet Genome Res 107:139. 2004

Collaborators

Detail Information

Publications93

  1. doi request reprint Molecular genetics of coat colour variations in White Galloway and White Park cattle
    B Brenig
    Institute of Veterinary Medicine, Burckhardtweg 2, D 37077, Gottingen, Germany
    Anim Genet 44:450-3. 2013
    ..Our data suggest that the white coat colour variations in White Galloway cattle and White Park cattle are caused by a dose-dependent effect based on the ploidy of aberrant insertions and inheritance of the KIT gene on chromosome 29. ..
  2. pmc PrPSc spreading patterns in the brain of sheep linked to different prion types
    Wiebke M Wemheuer
    Prion and Dementia Research Unit, Department of Neuropathology, University Medical Center, Georg August University, Robert Koch Str, 40, 37075 Goettingen, Germany
    Vet Res 42:32. 2011
    ....
  3. pmc A high resolution physical and RH map of pig chromosome 6q1.2 and comparative analysis with human chromosome 19q13.1
    Flávia Martins-Wess
    Institute of Animal Breeding and Genetics, School of Veterinary Medicine Hannover, Bunteweg 17p, 30559 Hannover, Germany
    BMC Genomics 4:20. 2003
    ..The recently constructed porcine IMNpRH2 panel allowed us to use this approach for the construction of high-resolution physical maps of SSC 6q1.2...
  4. pmc X- and Y-chromosome specific variants of the amelogenin gene allow sex determination in sheep (Ovis aries) and European red deer (Cervus elaphus)
    I Pfeiffer
    Department of Molecular Biology, Institute of Veterinary Medicine, Goettingen, Germany
    BMC Genet 6:16. 2005
    ..Thus, the detection of Y- and X-chromosome specific sequences is advantageous...
  5. pmc Genome-wide QTL mapping for three traits related to teat number in a White Duroc x Erhualian pig resource population
    Nengshui Ding
    Key Laboratory for Animal Biotechnology of Jiangxi Province and the Ministry of Agriculture of China, Jiangxi Agricultural University, Nanchang 330045, PR China
    BMC Genet 10:6. 2009
    ....
  6. pmc A genome-wide scan for quantitative trait loci affecting limb bone lengths and areal bone mineral density of the distal femur in a White Duroc x Erhualian F2 population
    Huirong Mao
    Key Laboratory for Animal Biotechnology of Jiangxi Province and the Ministry of Agriculture of China, Jiangxi Agricultural University, Nanchang 330045, PR China
    BMC Genet 9:63. 2008
    ..The aim of this study was to identify quantitative trait loci (QTL) affecting limb bone lengths and BMD of the distal femur in a White Duroc x Erhualian resource population...
  7. ncbi request reprint Molecular cloning, mapping, and functional analysis of the bovine sulfate transporter SLC26a2 gene
    Bertram Brenig
    Institute of Veterinary Medicine, University of Gottingen, Groner Landstrasse 2, D 37073, Gottingen, Germany
    Gene 319:161-6. 2003
    ..The Ile520Ser exchange influences the sulfate uptake as measured in primary fibroblasts isolated from testis and in immortalized fibroblastoid bovine cell lines...
  8. ncbi request reprint Analysis of the 5' region of the canine PAX3 gene and exclusion as a candidate for Dalmatian deafness
    B Brenig
    Institute of Veterinary Medicine, University of Goettingen, Goettingen, Germany
    Anim Genet 34:47-50. 2003
    ..These results were confirmed by a two-point linkage analysis in 203 Dalmatians transmitting deafness. Our data clearly show that the canine PAX3 gene can be excluded as candidate for Dalmatian deafness...
  9. ncbi request reprint Analysis of blood clotting factor activities in canine Legg-Calvé-Perthes' disease
    B Brenig
    Institute of Veterinary Medicine, University of Gottingen, Germany
    J Vet Intern Med 13:570-3. 1999
    ..All dogs had normal plasma activities of these factors, indicating that in these dogs LCP disease was not caused by deficiencies of the analyzed blood clotting factors...
  10. ncbi request reprint Assignment of the equine solute carrier 26A2 gene (SLC26A2) to equine chromosome 14q15-->q21 (ECA14q15-->q21) by in situ hybridization and radiation hybrid panel mapping
    B Brenig
    Institute of Veterinary Medicine, Georg August University of Gottingen, Germany
    Cytogenet Genome Res 107:139. 2004
  11. doi request reprint Shotgun metagenomics of biological stains using ultra-deep DNA sequencing
    B Brenig
    Institute of Veterinary Medicine, University of Gottingen, Burckhardtweg 2, Gottingen, Germany
    Forensic Sci Int Genet 4:228-31. 2010
    ..5% DNA of unknown origin. Our data demonstrate that 454 pyrosequencing has the potential to become a powerful tool not only in basic research but also in the metagenomic analysis of biological trace materials for forensic genetics...
  12. ncbi request reprint Characterization of the PGK2 associated microsatellite S0719 on SSC7 suitable for parentage and QTL diagnosis
    Kefei Chen
    Institute of Veterinary Medicine, University of Gottingen, Gottingen, Germany
    Anim Biotechnol 17:43-9. 2006
    ..Finally, S0719 is also a valuable STS marker for fine-mapping QTL on SSC7 as position 77.5 cM is located in 25 QTL intervals...
  13. ncbi request reprint Molecular characterization of the porcine testis-specific phosphoglycerate kinase 2 (PGK2) gene and its association with male fertility
    Kefei Chen
    Institute of Veterinary Medicine, University of Gottingen, Gottingen, Germany
    Mamm Genome 15:996-1006. 2004
    ..The results showed that SNP-B has a positive significant effect on semen volume in the breed Pietrain (p = 0.08), i.e., boars carrying genotype CC revealed an increased volume of 49 ml compared with boars having the genotype AA...
  14. ncbi request reprint Isolation and molecular characterization of the porcine stearoyl-CoA desaturase gene
    Jun Ren
    Institute of Veterinary Medicine, Georg August University of Gottingen, Groner Landstrasse 2, Gottingen 37073, Germany
    Gene 340:19-30. 2004
    ..Reverse transcription (RT)-PCR result indicates that the SCD gene is expressed ubiquitously in pigs...
  15. ncbi request reprint Two highly polymorphic microsatellites between the canine DAG1 and BSN genes on CFA20q15.1-15.2
    T Leeb
    Institute of Veterinary Medicine, University of Gottingen, Germany
    Anim Genet 31:337. 2000
  16. pmc Genome aberrations in canine mammary carcinomas and their detection in cell-free plasma DNA
    Julia Beck
    Chronix Biomedical, Gottingen, Germany
    PLoS ONE 8:e75485. 2013
    ..The possibility exists that ddPCR can be expanded to screening for common cancer related variants. ..
  17. doi request reprint Analysis of circulating DNA distribution in pregnant and nonpregnant dairy cows
    Jennifer Mayer
    Institute of Veterinary Medicine, University of Gottingen, Gottingen, Germany
    Biol Reprod 88:29. 2013
    ..To our knowledge, this is the first study to comprehensively characterize the circulating, cell-free DNA profile in sera from pregnant and nonpregnant cows across early gestation...
  18. pmc Targeted oligonucleotide-mediated microsatellite identification (TOMMI) from large-insert library clones
    Kefei Chen
    Institute of Veterinary Medicine, University of Gottingen, Burckhardtweg 2, 37077, Gottingen, Germany
    BMC Genet 6:54. 2005
    ..In order to directly generate microsatellites from large-insert libraries a sequencing approach with repeat-containing oligonucleotides is introduced...
  19. ncbi request reprint Characterization of the porcine multicopy ribosomal protein SA/37-kDa laminin receptor gene family
    Christoph Knorr
    Institute of Veterinary Medicine, Georg August University of Goettingen, Goettingen, Germany
    Gene 395:135-43. 2007
    ..We conclude that the pig genome contains multiple copies of the RPSA sequence probably as a consequence to maintain the multifunctionality of the mature protein...
  20. ncbi request reprint Molecular analysis and chromosomal assignment of the canine CALC-I/alpha-CGRP gene
    S Wende
    Institute of Veterinary Medicine, University of Gottingen, Groner Landstrasse 2, 37073 Gottingen, Germany
    Mamm Genome 11:736-40. 2000
    ..31 kDa (pI 7.9) and 14.13 kDa (pI 8.5) of the calcitonin and alpha-CGRP precursor, respectively...
  21. ncbi request reprint Detection of a polymorphic 27 bp insertion/deletion in exon 4 of the canine calcitonin/calcitonin gene-related peptide gene I (CALCA)
    S Wende
    Institute of Veterinary Medicine, University of Gottingen, Germany
    Anim Genet 31:238-9. 2000
  22. pmc Genomic organization of the dog dystroglycan gene DAG1 locus on chromosome 20q15.1-q15.2
    T Leeb
    Institute of Veterinary Medicine, University of Gottingen, 37073 Gottingen, Germany
    Genome Res 10:295-301. 2000
    ..Therefore, this study defines a novel syntenic region among dog chromosome 20q15, human chromosome 3p21, and murine chromosome 9F...
  23. ncbi request reprint A polymorphic microsatellite in intron 2 of the bovine proteolipid protein (PLP) gene
    I Pfeiffer
    University of Goettingen, Department of Molecular Biology, Germany
    Anim Genet 29:410-1. 1998
  24. ncbi request reprint Molecular characterization and chromosomal assignment of the canine protein C gene
    T Leeb
    Institute of Veterinary Medicine, University of Gottingen, Groner Landstrasse 2, 37073 Gottingen, Germany
    Mamm Genome 10:134-9. 1999
    ..From these data we conclude that in contrast to human, canine Morbus Perthes disease is most likely not caused by mutations within the protein C gene...
  25. pmc Diagnostic polymorphisms in the mitochondrial cytochrome b gene allow discrimination between cattle, sheep, goat, roe buck and deer by PCR-RFLP
    Ina Pfeiffer
    Institute of Veterinary Medicine, Georg August University of Gottingen, Groner Landstrasse 2, D 37073 Gottingen, Germany
    BMC Genet 5:30. 2004
    ..The PCR-RFLP-method is an inexpensive tool in forensic science, even if the template is degraded or contains only traces of DNA from various species...
  26. doi request reprint Serum nucleic acids in an experimental bovine transmissible spongiform encephalopathy model
    Julia Beck
    Institute of Veterinary Medicine, University of Goettingen, Germany
    Zoonoses Public Health 56:384-90. 2009
    ..In conclusion, RGNAS polymorphism detection may have general applications for the study of other emerging zoonoses...
  27. ncbi request reprint Structural analysis and transcript processing of the bovine proteolipid protein (PLP) gene
    B G Baumgartner
    Institute of Veterinary Medicine, University of Gottingen, Germany
    DNA Seq 10:379-85. 2000
    ..Three main transcripts were detected in adult cattle in the range of 3200, 2400, and 1600 nucleotides using Northern blot analysis. An additional shorter transcript was detected in the cerebrum of calves...
  28. ncbi request reprint The porcine gene TBP10 encodes a protein homologous to the human tat-binding protein/26S protease subunit family
    T Leeb
    Institute of Veterinary Medicine, University of Goettingen, Germany
    Mamm Genome 7:180-5. 1996
    ..Like DdTBP1O and other members of the protein family, the porcine TBP1O harbors a leucine zipper motif in the N-terminal region and a domain characteristics of ATP-dependent proteases in the C-terminal region...
  29. ncbi request reprint Structural and functional analysis of the porcine secretory carrier membrane protein 1 gene (SCAMP1)
    G Wen
    Institute of Veterinary Medicine, University of Gottingen, Germany
    Mamm Genome 9:536-9. 1998
    ..The promoter of the SCAMP1 gene is TATA-box-less, and transcription starts at a G-nucleotide 133 nt upstream the start codon...
  30. ncbi request reprint Assignment of the CALC-A/alpha-CGRP gene (CALCA) to porcine chromosome SSC2p13-->p11 by fluorescence in situ hybridization and by analysis of somatic cell and radiation hybrid panels
    C Knorr
    Institute of Veterinary Medicine, Georg August University of Gottingen, Gottingen, Germany
    Cytogenet Genome Res 97:140F. 2002
  31. ncbi request reprint Molecular analysis of the porcine proteolipid protein (PLP) gene
    B G Baumgartner
    Institute of Veterinary Medicine, University of Gottingen, Groner Landstrasse 2, 37073 Gottingen, Germany
    Mamm Genome 10:895-9. 1999
    ..Three main transcripts were detected in adult pigs in the range of 3200, 2400, and 1600 nucleotides with Northern blot analysis. The usage of an alternative splice site within exon 3 was shown...
  32. doi request reprint Early pregnancy diagnosis in dairy cows using circulating nucleic acids
    Jennifer Mayer
    Institute of Veterinary Medicine, University of Gottingen, Gottingen, Germany
    Theriogenology 79:173-9. 2013
    ..These results suggest that CNAs can be used as biomarkers for the detection of early pregnancy in cattle...
  33. pmc Polymorphisms in the bovine HSP90AB1 gene are associated with heat tolerance in Thai indigenous cattle
    Rangsun Charoensook
    Institute of Veterinary Medicine, Georg August University Gottingen, 37077 Gottingen, Germany
    Trop Anim Health Prod 44:921-8. 2012
    ..Polymorphisms within HSP90AB1 were not causative for the physiological responses; however, we propose that they should at least be used as genetic markers to select appropriate breeds for hot climates...
  34. ncbi request reprint Structural and expression analysis of the porcine FUS2 gene
    Kesinee Gatphayak
    Institute of Veterinary Medicine, University of Gottingen, Groner Landstrasse 2 37073 Göttingen, Germany
    Gene 337:105-11. 2004
    ..Knowledge of structure and function of the respective porcine genes and proteins is important. Pigs-in particular minipigs-will be the non-rodent biomodels for human oncology and cancer therapy in the future...
  35. ncbi request reprint Assignment of the porcine stearoyl-CoA desaturase (SCD) gene to SSC14q27 by fluorescence in situ hybridization and by hybrid panel mapping
    J Ren
    Institute of Veterinary Medicine, Georg August University of Gottingen, Gottingen, Germany
    Anim Genet 34:471-3. 2003
  36. ncbi request reprint Characterization and chromosome assignment of the canine gamma-sarcoglycan gene (SGCG) to CFA 25q21-->q23
    K Conrad
    Institute of Veterinary Medicine, University of Gottingen, Germany
    Cytogenet Cell Genet 94:186-9. 2001
    ..The chromosome assignment of the canine SGCG gene to CFA 25q21-->q23 confirms that the canine syntenic group 10 corresponds to CFA 25 and also supports the findings of human-canine reciprocal chromosome painting...
  37. ncbi request reprint Molecular cloning of the porcine beta-1,2-N-acetylglucosaminyltransferase II gene and assignment to chromosome 1q23-q27
    T Leeb
    Institute of Veterinary Medicine, University of Gottingen, Germany
    Biochim Biophys Acta 1336:361-6. 1997
    ..The mapping data of the cell panel were confirmed by fluorescence in situ hybridization (FISH) on metaphase chromosomes...
  38. ncbi request reprint Analysis of canine protein C gene polymorphisms
    T Leeb
    Institute of Veterinary Medicine, University of Gottingen, Germany
    Anim Genet 30:237-8. 1999
  39. ncbi request reprint Isolation and characterization of a new FHL1 variant (FHL1C) from porcine skeletal muscle
    A Krempler
    Institute of Veterinary Medicine, University of Gottingen, Germany
    Cytogenet Cell Genet 90:106-14. 2000
    ..The porcine FHL1C gene was assigned to the distal part of the long arm of the X chromosome by fluorescence in situ hybridization and screening of a somatic porcine/rodent cell hybrid panel...
  40. ncbi request reprint Genomic structures and sequences of two closely linked genes (AMT, TCTA) on dog chromosome 20q15.1-->q15.2
    T Leeb
    Institute of Veterinary Medicine, University of Gottingen, Gottingen, Germany
    Cytogenet Cell Genet 89:98-100. 2000
    ..The 4-kb canine TCTA gene consists of three exons and probably represents a pseudogene. It is located adjacent to AMT and very close to DAG1 and BSN...
  41. ncbi request reprint Regulation of tissue-specific expression of the skeletal muscle ryanodine receptor gene
    S Schmoelzl
    Institute of Veterinary Medicine, University of Gottingen, 37073 Gottingen, Federal Republic of Germany
    J Biol Chem 271:4763-9. 1996
    ....
  42. ncbi request reprint Genotyping of ovine prion protein gene (PRNP) variants by PCR with melting curve analysis
    Ekkehard Schütz
    Institute of Veterinary Medicine, Georg August University, Burckhardtweg 2, 37077 Gottingen, Germany
    Clin Chem 52:1426-9. 2006
    ..For this purpose, reliable and cost-effective genotyping is needed...
  43. ncbi request reprint Assignment of the porcine ryanodine receptor 3 gene (RYR3) to chromosome 7q22-->q23
    T Leeb
    Institute of Veterinary Medicine, University of Gottingen, Gottingen, Germany
    Cytogenet Cell Genet 83:244-5. 1998
  44. ncbi request reprint cDNA cloning and sequencing of the human ryanodine receptor type 3 (RYR3) reveals a novel alternative splice site in the RYR3 gene
    T Leeb
    Institute of Veterinary Medicine, University of Gottingen, Germany
    FEBS Lett 423:367-70. 1998
    ..A previously unidentified alternative splice site was detected generating a transcript that lacked bases 11,569-11,650 and encoded a truncated protein...
  45. ncbi request reprint Site-directed mutagenesis of boar proacrosin reveals residues involved in binding of zona pellucida glycoproteins
    S Jansen
    Veterinary Institute of Göttingen, Germany
    Mol Reprod Dev 51:184-92. 1998
    ..Identification and elucidation of the stereochemistry of these charged moieties will aid design of new kinds of nonsteroidal antifertility agents...
  46. ncbi request reprint Partial cloning and assignment of the canine bassoon gene (BSN) to chromosome 20q15.1-->q15.2
    T Leeb
    Institute of Veterinary Medicine, University of Gottingen, Gottingen, Germany
    Cytogenet Cell Genet 86:331-2. 1999
  47. ncbi request reprint Emulation of an ELISA reader and quantitative image analysis using the computer program Digital-OD
    S Jansen
    Tierarztliches Institut, Universitat Gottingen Abteilung Molekularbiologie, Germany
    Biotechniques 24:998-1001. 1998
    ..97). Thus, the software is useful for a wide number of applications. Further, the program is easy to handle and is available free of charge...
  48. ncbi request reprint Forensic DNA-typing of dog hair: DNA-extraction and PCR amplification
    I Pfeiffer
    Institute of Veterinary Medicine, Georg August University of Gottingen, Groner Landstrasse 2, Göttingen D 37073, Germany
    Forensic Sci Int 141:149-51. 2004
    ..Here we describe an experimental study about dog hairs by means of a Ca(2+) improved DNA-extraction method, quantification and amplification...
  49. ncbi request reprint Phylogenetics of the European Dahomey miniature cattle based on mitochondrial D-loop region DNA sequence
    I Pfeiffer
    Institute of Veterinary Medicine, University of Goettingen, Goettingen, Germany
    Anim Genet 36:179-81. 2005
  50. ncbi request reprint A polymorphic microsatellite located within the second intron of the methylmalonyl-CoA mutase (MUT) gene on SSC 1
    S Duscher
    Institute of Veterinary Medicine, University of Gottingen, Germany
    Anim Genet 31:339. 2000
  51. ncbi request reprint Assignment of the beta-N-acetylhexosaminidase gene (HEXB) to porcine chromosome SSC2q21-->q22 by fluorescence in situ hybridization and by analysis of somatic cell and radiation hybrid panels
    A Mueller
    Institute of Veterinary Medicine, Georg August University of Gottingen, Germany
    Cytogenet Genome Res 101:178. 2003
  52. ncbi request reprint Assignment of the sperm protein zona receptor tyrosine kinase gene (SPRMTK) to porcine chromosome SSC3q11-->q12 by fluorescence in situ hybridization and by analysis of somatic cell and radiation hybrid panels
    L Bull
    Institute of Veterinary Medicine, Georg August University of Gottingen, Germany
    Cytogenet Genome Res 101:178. 2003
  53. ncbi request reprint Assignment of the porcine hyaluronidase-3 (HYAL3) gene to SSC13-->q21 by FISH and confirmation by hybrid panel analyses
    K Gatphayak
    Institute of Veterinary Medicine, Georg August University of Gottingen, Germany
    Cytogenet Genome Res 101:178. 2003
  54. ncbi request reprint Assignment of the phosphoglycerate kinase 2 (PGK2) gene to porcine chromosome 7q14-q15 by fluorescence in situ hybridization and by analysis of somatic cell and radiation hybrid panels
    K F Chen
    Institute of Veterinary Medicine, University of Gottingen, Gottingen, Germany
    Anim Genet 35:71-2. 2004
  55. pmc Similarities between forms of sheep scrapie and Creutzfeldt-Jakob disease are encoded by distinct prion types
    Wiebke M Wemheuer
    Prion and Dementia Research Unit, Department of Neuropathology, University Medical Center Goettingen, Goettingen, Germany
    Am J Pathol 175:2566-73. 2009
    ..This should be taken into consideration when discussing interspecies transmission...
  56. ncbi request reprint Identification of a mutation in the ovine uroporphyrinogen decarboxylase (UROD) gene associated with a type of porphyria
    R Nezamzadeh
    Institute of Veterinary Medicine, University of Gottingen, Gottingen, Germany
    Anim Genet 36:297-302. 2005
    ..We identified a single point mutation (C --> T) in UROD which leads to an amino acid substitution at Leu 131 Pro, which is located within the active cleft site of the UROD protein...
  57. ncbi request reprint The porcine skeletal muscle ryanodine receptor gene structure coding region 1 to 10614 harbouring 71 exons
    G Wen
    Institute of Veterinary Medicine, University of Goettingen, Germany
    Anim Genet 27:297-304. 1996
    ..7 kb of chromosomal DNA of chromosome 6q12. This region harbours exons 1 to 71 coding for 3538 amino acids (69.6%) of the ryanodine receptor 1...
  58. ncbi request reprint Chromosomal assignment of porcine oncogenic and apoptopic genes CACNA2D2, TUSC4, ATP2A1, COL1A1, TAC1, BAK1 and CASP9
    C Knorr
    Institute of Veterinary Medicine, Georg August University of Gottingen, Burckhardtweg 2, 37077 Gottingen, Germany
    Anim Genet 37:523-5. 2006
  59. ncbi request reprint Frequency of the canine leucocyte adhesion deficiency (CLAD) mutation among Irish red setters in Germany
    I Pfeiffer
    Institute of Veterinary Medicine, University of Gottingen, Gottingen, Germany
    J Anim Breed Genet 122:140-2. 2005
    ..The present report describes the analysis of the single nucleotide polymorphism in 289 Irish red setters by DNA sequencing. The frequency of CLAD carriers in Germany is 11%...
  60. ncbi request reprint Partial genomic structure of the bovine PIT1 gene and characterization of a HinfI transition polymorphism in exon 6
    B Dierkes
    Institute of Veterinary Medicine, University of Gottingen, Germany
    Anim Genet 29:405. 1998
  61. ncbi request reprint Genomic structure and nucleotide polymorphisms of the porcine agouti signalling protein gene (ASIP)
    T Leeb
    Institute of Veterinary Medicine, University of Gottingen, Germany
    Anim Genet 31:335-6. 2000
  62. ncbi request reprint Assignment of the equine colony stimulating factor 1 receptor gene (CSF1R) to equine chromosome 14q15-->q16 (ECA14q15-->q16) by in situ hybridization and radiation hybrid panel mapping
    J Beck
    Institute of Veterinary Medicine, Georg August University of Gottingen, Gottingen, Germany
    Cytogenet Genome Res 109:533. 2005
  63. ncbi request reprint Assignment of the phosphoglycerate kinase 1 (PGK1) gene to porcine chromosome Xq12-q13 by fluorescence in situ hybridization and hybrid panel analyses
    K F Chen
    Institute of Veterinary Medicine, University of Gottingen, Groner Landstrasse 2, 37073 Gottingen, Germany
    Anim Genet 35:143-5. 2004
  64. ncbi request reprint Molecular cloning and chromosomal assignment of the porcine 54 and 56 kDa vacuolar H(+)-ATPase subunit gene (V-ATPase)
    D Hui
    Institute of Veterinary Medicine, University of Gottingen, Groner Landstrasse 2, 37073 Gottingen, Germany
    Mamm Genome 10:266-70. 1999
    ..8 kDa. Amino acid and DNA sequence comparison revealed that the porcine V-ATPase subunit exhibits a significant homology to the VMA13 subunit of Saccharomyces cerevisiae V-ATPase complex and V-ATPase subunit of Caenorhabditis elegans...
  65. ncbi request reprint Sequence analysis of the equine SLC26A2 gene locus on chromosome 14q15-->q21
    M Hansen
    Institute of Veterinary Medicine, Georg August University of Gottingen, Gottingen, Germany
    Cytogenet Genome Res 118:55-62. 2007
    ..The overall frequency of the newly described variant T is low (between 2% and 6%). Simulation studies on the protein conformation predict structural protein changes mediated by the SNP...
  66. pmc The G32E functional variant reduces activity of PPARD by nuclear export and post-translational modification in pigs
    Yanyu Duan
    Key Laboratory for Animal Biotechnology of Jiangxi Province and the Ministry of Agriculture of China, Jiangxi Agricultural University, Nanchang, China Institute of Veterinary Medicine, Georg August University of Gottingen, Gottingen, Germany
    PLoS ONE 8:e75925. 2013
    ..Taken together, our findings strongly support that G32E is a functional variant that plays a key role in biological activity of sPPARD, which advances our understanding of the underlying mechanism of sPPARD G32E for ear size in pigs. ..
  67. pmc Extrinsic and intrinsic regulation of DOR/TP53INP2 expression in mice: effects of dietary fat content, tissue type and sex in adipose and muscle tissues
    Carolin Fromm-Dornieden
    Institute of Veterinary Medicine, University of Gottingen, Burckhardtweg 2, 37077, Gottingen, Germany
    Nutr Metab (Lond) 9:86. 2012
    ..abstract:..
  68. pmc Bov-tA short interspersed nucleotide element sequences in circulating nucleic acids from sera of cattle with bovine spongiform encephalopathy (BSE) and sera of cattle exposed to BSE
    Ekkehard Schütz
    Institute of Veterinary Medicine, Groner Landstrasse 2, D 37073 Gottingen, Germany
    Clin Diagn Lab Immunol 12:814-20. 2005
    ..6%; P < 0.001). This study shows that BSE-confirmed and cohort animals possess a unique profile of SINE-associated serum CNA that can be utilized as a marker that highly correlates to BSE exposure...
  69. ncbi request reprint Application of bovine microsatellite markers for genetic diversity analysis of European bison (Bison bonasus)
    T Roth
    Institute of Veterinary Medicine, Georg August University of Gottingen, Gottingen, Germany
    J Anim Breed Genet 123:406-9. 2006
    ..The availability of a heterologous set of multiplexed microsatellite markers derived from cattle opens an avenue for collecting profound genetic data for efficient conservation management strategies of the European bison...
  70. ncbi request reprint Assignment of the porcine FUS1 gene to SSC13q21q22 by somatic cell and radiation hybrid panel mapping
    K Gatphayak
    Institute of Veterinary Medicine, Georg August University of Gottingen, Germany
    Cytogenet Genome Res 103:203I. 2003
  71. ncbi request reprint Assignment of the canine paired-box 3 (PAX3) gene to chromosome 37q16-->q17 by in situ hybridization
    A Krempler
    Institute of Veterinary Medicine, University of Gottingen, Germany
    Cytogenet Cell Genet 90:66-7. 2000
  72. ncbi request reprint Genomic structure of the 5' end of the porcine ryanodine receptor 3 gene (RYR3)
    A Giese
    Instituyte of Veterinary Medicine, University of Gottingen, Germany
    DNA Seq 11:175-9. 2000
    ..Physical mapping of the isolated PAC clones revealed that the complete porcine RYR3 gene spans more than 200 kb of genomic DNA...
  73. ncbi request reprint Molecular characterization of porcine hyaluronidase genes 1, 2, and 3 clustered on SSC13q21
    K Gatphayak
    Institute of Veterinary Medicine, Gottingen, Germany
    Cytogenet Genome Res 106:98-106. 2004
    ..Expression of hyaluronidases was determined by RT-PCR and quantitative PCR. Broad gene expression was observed in different tissues for the three genes, respectively...
  74. ncbi request reprint Assignment of the beta-glucuronidase (GUSB) gene to porcine chromosome SSC3p16-->p14 by FISH and confirmation by hybrid panel analyses
    J Beck
    Institute of Veterinary Medicine, Georg August University of Gottingen, Gottingen, Germany
    Cytogenet Genome Res 97:277G. 2002
  75. ncbi request reprint Assignment of the ovine uroporphyrinogen decarboxylase (UROD) gene to chromosome 1p34 --> p36 by fluorescence in situ hybridization
    R Nezamzadeh
    Institute of Veterinary Medicine, Georg August University of Goettingen, Germany
    Cytogenet Genome Res 106:142. 2004
  76. ncbi request reprint Partial genomic structure of the bovine CD18 gene and the refinement of test for bovine leukocyte adhesion deficiency
    B Kriegesmann
    Institute of Veterinary Medicine, University of Goettingen, Germany
    J Dairy Sci 80:2547-9. 1997
  77. pmc Novel polysome messages and changes in translational activity appear after induction of adipogenesis in 3T3-L1 cells
    Carolin Fromm-Dornieden
    Institute of Veterinary Medicine, University of Gottingen, Gottingen, Germany
    BMC Mol Biol 13:9. 2012
    ..Changes in relative abundance in unbound and polysomal mRNA pools were calculated to detect putative changes in translational activity. Changes of expression levels of selected genes were verified by qPCR and Western blotting...
  78. ncbi request reprint Characterization of two SNPs (single nucleotide polymorphisms) in the porcine INSL3 gene and their exclusion as a common genetic basis of hernia inguinalis in pigs
    Christoph Knorr
    Institute of Veterinary Medicine, Georg August University of Goettingen, Goettingen, Germany
    Biochem Genet 42:11-9. 2004
    ..Screening of the two SNPs in a population of hernia inguinalis affected full and half sib piglets (n = 223) revealed that the SNPs can be excluded as a common genetic basis for this congenital disorder in this pedigree...
  79. ncbi request reprint Analysis of mitochondrial D-loop region casts new light on domestic water buffalo (Bubalus bubalis) phylogeny
    Gerold Kierstein
    Institute of Veterinary Medicine, Georg August University, Groner Landstrasse 2, 37073 Gottingen, Germany
    Mol Phylogenet Evol 30:308-24. 2004
    ..We are also discussing indications for an independent domestication of buffaloes in China...
  80. ncbi request reprint Structural analysis of the porcine skeletal muscle ryanodine receptor gene coding region 3385 to 4623
    T Leeb
    Institute of Veterinary Medicine, University of Goettingen, Germany
    Mamm Genome 7:152-4. 1996
  81. doi request reprint Radiation hybrid mapping of seven porcine calcium channel genes (CATSPER1-4 and CNGA1-3) associated with male fertility
    Y Y Xing
    Institute of Veterinary Medicine, Georg August University of Gottingen, Burckhardtweg 2, 37077 Gottingen, Germany
    Anim Genet 39:573-4. 2008
  82. ncbi request reprint Characterization and chromosome localization of a processed pseudogene related to the bovine laminin receptor gene family
    M Germerodt
    Institute of Veterinary Medicine, Georg August University, Gottingen, Germany
    Cytogenet Genome Res 107:123-7. 2004
    ..Considering the existence of several human laminin receptor pseudogenes forming a complex family, any knowledge of even pseudogene sequences might be helpful to isolate the functional bovine laminin receptor gene...
  83. doi request reprint Chromosomal assignment of eight porcine genes involved in apoptosis
    C Beuermann
    Institute of Veterinary Medicine, Georg August University of Gottingen, Burckhardtweg 2, 37077 Gottingen, Germany
    Anim Genet 39:330-1. 2008
  84. doi request reprint Implication of complex vertebral malformation and bovine leukocyte adhesion deficiency DNA-based testing on disease frequency in the Holstein population
    E Schutz
    Institute of Veterinary Medicine, Georg August University of Gottingen, Burckhardtweg 2, 37077 Gottingen, Germany
    J Dairy Sci 91:4854-9. 2008
    ..The different selection strategies against the lethal recessive allele in CVM and BLAD are reflected in the different reduction rates of the specific allele frequencies...
  85. ncbi request reprint Zinc finger proteins: watchdogs in muscle development
    A Krempler
    Institute of Veterinary Medicine, Gottingen, Germany
    Mol Gen Genet 261:209-15. 1999
    ..This review discusses several zinc finger proteins that have been characterized as regulators of muscle development and muscle-specific gene expression...
  86. doi request reprint Molecular analysis of carbohydrate N-acetylgalactosamine 4-O sulfotransferase 8 (CHST8) as a candidate gene for bovine spongiform encephalopathy susceptibility
    R Morina
    Institute of Veterinary Medicine, Georg August University, Goettingen, Germany
    Anim Genet 41:85-8. 2010
    ..Significant differences in the allele, genotype and haplotype frequencies between BSE-affected and healthy cows indicate an association of sequence variant g.37254017G>T with the development of the disease in Brown Swiss cattle...
  87. ncbi request reprint Detection of classical and atypical/Nor98 scrapie by the paraffin-embedded tissue blot method
    W M Wemheuer
    Prion and Dementia Research Unit, Department of Neuropathology, University Medical Centre, Gottingen, 37075 Gottingen, Germany
    Vet Rec 164:677-81. 2009
    ....
  88. doi request reprint Tissue calcium content in piglets with inguinal or scrotal hernias or cryptorchidism
    C Beuermann
    Institute of Veterinary Medicine, Georg August University of Gottingen, Burckhardtweg 2, 37077 Gottingen, Germany
    J Comp Pathol 140:182-6. 2009
    ..184, 0.144 and 0.048 mg/g wt for sacs, peritoneal tissue and cremaster muscles, respectively). These findings suggest that there may be perturbation of the apoptotic pathway in the urogenital tissues of affected piglets...
  89. ncbi request reprint The mutation causing the black-and-tan pigmentation phenotype of Mangalitza pigs maps to the porcine ASIP locus but does not affect its coding sequence
    Cord Drogemuller
    Institute of Animal Breeding and Genetics, University of Veterinary Medicine Hannover, Hannover, 30559, Germany
    Mamm Genome 17:58-66. 2006
    ..The a(t) mutation is therefore probably a regulatory ASIP mutation that alters its dorsoventral expression pattern...
  90. ncbi request reprint [Cellular nucleic acids in serum and plasma as new diagnostic tools]
    Bertram Brenig
    Tierärztlichen Institut, Universitat Gottingen, Gottingen, BRD
    Berl Munch Tierarztl Wochenschr 115:122-4. 2002
    ....
  91. ncbi request reprint Analysis of sequence variability of the bovine prion protein gene (PRNP) in German cattle breeds
    Petra Sander
    Institute of Animal Breeding and Genetics, School of Veterinary Medicine Hannover, Bünteweg 17 p, 30559 Hannover, Germany
    Neurogenetics 5:19-25. 2004
    ..However, we identified a 23-bp insertion/deletion polymorphism in the putative PRNP promoter region that shows a significant association with BSE susceptibility in our animals...
  92. pmc Combined analysis of data from two granddaughter designs: A simple strategy for QTL confirmation and increasing experimental power in dairy cattle
    Jörn Bennewitz
    Institut für Tierzucht und Tierhaltung, Christian Albrechts Universitat, 24098 Kiel, Germany
    Genet Sel Evol 35:319-38. 2003
    ..This study demonstrated the potential benefits of a combined analysis of data from different granddaughter designs...
  93. ncbi request reprint Racing, ornamental and city pigeons carry shiga toxin producing Escherichia coli (STEC) with different Shiga toxin subtypes, urging further analysis of their epidemiological role in the spread of STEC
    Katja Grossmann
    Tierseuchenkasse Baden Württemberg Geflügelgesundheitsdienst, Heidelberg
    Berl Munch Tierarztl Wochenschr 118:456-63. 2005
    ..Taking into account the close contact between fanciers and pigeons, these findings warrant a more critical appraisal of these zoonotic pathogens in pigeons...