C Bremer

Summary

Country: Germany

Publications

  1. ncbi request reprint In vivo imaging of integrin alpha v beta 3 expression using fluorescence-mediated tomography
    Angelika von Wallbrunn
    Department of Clinical Radiology, University of Munster, Albert Schweitzer Strasse 33, 48129, Munster, Germany
    Eur J Nucl Med Mol Imaging 34:745-54. 2007
  2. pmc Differentiation of angiogenic burden in human cancer xenografts using a perfusion-type optical contrast agent (SIDAG)
    Alexander Wall
    Department of Clinical Radiology, University Hospital of Munster, 48129 Munster, Germany
    Breast Cancer Res 10:R23. 2008
  3. ncbi request reprint Preliminary clinical experience with laser-induced interstitial thermotherapy in patients with hepatocellular carcinoma
    C Bremer
    Institute for Clinical Radiology, Westfaelische Wilhelms University, Meunster, Germany
    J Magn Reson Imaging 8:235-9. 1998
  4. ncbi request reprint Imaging of differential protease expression in breast cancers for detection of aggressive tumor phenotypes
    Christoph Bremer
    Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Boston, USA
    Radiology 222:814-8. 2002
  5. ncbi request reprint Optical imaging of spontaneous breast tumors using protease sensing 'smart' optical probes
    Christoph Bremer
    Department of Clinical Radiology, University of Muenster, Germany
    Invest Radiol 40:321-7. 2005
  6. ncbi request reprint High-dose Gd-DTPA vs. Bis-Gd-mesoporphyrin for monitoring laser-induced tissue necrosis
    Christoph Bremer
    Department of Clinical Radiology, University of Muenster, Muenster, Germany
    J Magn Reson Imaging 21:801-8. 2005
  7. ncbi request reprint Optical-based molecular imaging: contrast agents and potential medical applications
    Christoph Bremer
    Department of Clinical Radiology, University of Munster, Albert Schweitzer Strasse 33, 48129 Munster, Germany
    Eur Radiol 13:231-43. 2003
  8. ncbi request reprint Accuracy of non-enhanced MRI to monitor histological lesion size during laser-induced interstitial thermotherapy
    Christoph Bremer
    Department of Clinical Radiology, University of Munster, Albert Schweitzer Str 33, 48129 Munster, Germany
    Eur Radiol 12:237-44. 2002
  9. ncbi request reprint RES-specific imaging of the liver and spleen with iron oxide particles designed for blood pool MR-angiography
    C Bremer
    Department of Clinical Radiology, Westfaelische Wilhelms Universitaet Muenster, Albert Schweitzer Strasse 33, D 48129 Muenster, Germany
    J Magn Reson Imaging 10:461-7. 1999
  10. ncbi request reprint In vivo molecular target assessment of matrix metalloproteinase inhibition
    C Bremer
    Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, USA
    Nat Med 7:743-8. 2001

Collaborators

Detail Information

Publications59

  1. ncbi request reprint In vivo imaging of integrin alpha v beta 3 expression using fluorescence-mediated tomography
    Angelika von Wallbrunn
    Department of Clinical Radiology, University of Munster, Albert Schweitzer Strasse 33, 48129, Munster, Germany
    Eur J Nucl Med Mol Imaging 34:745-54. 2007
    ..We therefore synthesised an alpha v beta(3) targeted fluorochrome and imaged tumour xenografts with different alpha v beta(3) expression levels using both planar and tomographic optical imaging methods...
  2. pmc Differentiation of angiogenic burden in human cancer xenografts using a perfusion-type optical contrast agent (SIDAG)
    Alexander Wall
    Department of Clinical Radiology, University Hospital of Munster, 48129 Munster, Germany
    Breast Cancer Res 10:R23. 2008
    ....
  3. ncbi request reprint Preliminary clinical experience with laser-induced interstitial thermotherapy in patients with hepatocellular carcinoma
    C Bremer
    Institute for Clinical Radiology, Westfaelische Wilhelms University, Meunster, Germany
    J Magn Reson Imaging 8:235-9. 1998
    ..We conclude that LITT might be an effective minimally invasive palliative treatment option for patients with small unresectable HCC...
  4. ncbi request reprint Imaging of differential protease expression in breast cancers for detection of aggressive tumor phenotypes
    Christoph Bremer
    Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Boston, USA
    Radiology 222:814-8. 2002
    ..To determine if different expression levels of tumor cathepsin-B activity in well differentiated and undifferentiated breast cancers could be revealed in vivo with optical imaging...
  5. ncbi request reprint Optical imaging of spontaneous breast tumors using protease sensing 'smart' optical probes
    Christoph Bremer
    Department of Clinical Radiology, University of Muenster, Germany
    Invest Radiol 40:321-7. 2005
    ..The objective of this study was to determine if spontaneous breast cancer lesions can be detected by fluorescence reflectance imaging (FRI) and fluorescence mediated tomography (FMT) using protease-sensing optical probes...
  6. ncbi request reprint High-dose Gd-DTPA vs. Bis-Gd-mesoporphyrin for monitoring laser-induced tissue necrosis
    Christoph Bremer
    Department of Clinical Radiology, University of Muenster, Muenster, Germany
    J Magn Reson Imaging 21:801-8. 2005
    ....
  7. ncbi request reprint Optical-based molecular imaging: contrast agents and potential medical applications
    Christoph Bremer
    Department of Clinical Radiology, University of Munster, Albert Schweitzer Strasse 33, 48129 Munster, Germany
    Eur Radiol 13:231-43. 2003
    ....
  8. ncbi request reprint Accuracy of non-enhanced MRI to monitor histological lesion size during laser-induced interstitial thermotherapy
    Christoph Bremer
    Department of Clinical Radiology, University of Munster, Albert Schweitzer Str 33, 48129 Munster, Germany
    Eur Radiol 12:237-44. 2002
    ..For clinical purposes the lesion geometry seen during MR monitoring should therefore well extend the tumor margins...
  9. ncbi request reprint RES-specific imaging of the liver and spleen with iron oxide particles designed for blood pool MR-angiography
    C Bremer
    Department of Clinical Radiology, Westfaelische Wilhelms Universitaet Muenster, Albert Schweitzer Strasse 33, D 48129 Muenster, Germany
    J Magn Reson Imaging 10:461-7. 1999
    ..They might thus be used for comprehensive abdominal studies including contrast enhanced MR-angiography and RES-specific imaging...
  10. ncbi request reprint In vivo molecular target assessment of matrix metalloproteinase inhibition
    C Bremer
    Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, USA
    Nat Med 7:743-8. 2001
    ..The developed probes, together with novel near-infrared fluorescence imaging technology will enable the detailed analysis of a number of proteinases critical for advancing the therapeutic use of clinical proteinase inhibitors...
  11. ncbi request reprint [Progress in optical imaging]
    C Bremer
    Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Boston, USA
    Radiologe 41:131-7. 2001
    ..This overview outlines the basic principles of optical imaging and summarizes the current state of the art...
  12. ncbi request reprint Imaging cathepsin B up-regulation in HT-1080 tumor models using fluorescence-mediated molecular tomography (FMT)
    Vasilis Ntziachristos
    Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Charlestown 02129 2060, USA
    Acad Radiol 9:S323-5. 2002
  13. ncbi request reprint Molecular imaging of MMP expression and therapeutic MMP inhibition
    Christoph Bremer
    Center for Molecular Imaging Research, Massachusetts General Hospital, Charlestown, USA
    Acad Radiol 9:S314-5. 2002
  14. ncbi request reprint Steady-state blood volume measurements in experimental tumors with different angiogenic burdens a study in mice
    Christoph Bremer
    Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Bldg 149, 13th St, 5406, Charlestown, MA 02129, USA
    Radiology 226:214-20. 2003
    ....
  15. ncbi request reprint In vivo tomographic imaging of near-infrared fluorescent probes
    Vasilis Ntziachristos
    Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Bldg 149 13th Street 5406, Charlestown, MA 02129 2060, USA
    Mol Imaging 1:82-8. 2002
    ..This validation of FMT with FRI demonstrated the spatial congruence of fluorochrome activation as determined by the two techniques...
  16. ncbi request reprint Ex vivo evaluation of novel miniaturized laser-induced interstitial thermotherapy applicators for effective small-volume tissue ablation
    C Bremer
    Institute for Clinical Radiology, University of Muenster, Germany
    Invest Radiol 36:327-34. 2001
    ..The aim of this study was to compare the ablation properties of recently developed ultrasmall and small to standard LITT applicators...
  17. ncbi request reprint Contrast-enhanced blood-pool MR angiography with optimized iron oxides: effect of size and dose on vascular contrast enhancement in rabbits
    Thomas Allkemper
    Department of Clinical Radiology, University Hospital Munster, Albert Schweitzer Strasse 33, 48129 Munster, Germany
    Radiology 223:432-8. 2002
    ..To investigate intravascular enhancement of bolus-injectable small and ultrasmall superparamagnetic iron oxides (USPIOs) of different particle sizes and relaxivities for first-pass and blood-pool magnetic resonance (MR) angiography...
  18. ncbi request reprint Fluorescence imaging with near-infrared light: new technological advances that enable in vivo molecular imaging
    Vasilis Ntziachristos
    Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Building 149, 13th Street 5406, Charlestown MA 02129 2060, USA
    Eur Radiol 13:195-208. 2003
    ..We describe theoretical specifics, and we provide insight into its in vivo capacity and the sensitivity achieved. Finally, we discuss its clinical feasibility...
  19. ncbi request reprint Antiangiogenic tumor treatment: early noninvasive monitoring with USPIO-enhanced MR imaging in mice
    Thorsten Persigehl
    Department of Clinical Radiology, University Hospital Muenster, Albert Schweitzer Str 33, D 48129 Muenster, Germany
    Radiology 244:449-56. 2007
    ..To prospectively investigate steady-state blood volume measurements for early quantitative monitoring of antiangiogenic treatment with ultrasmall superparamagnetic iron oxide (USPIO)-enhanced magnetic resonance (MR) imaging...
  20. ncbi request reprint Non-invasive approaches to visualize the endothelin axis in vivo using state-of-the-art molecular imaging modalities
    C Höltke
    Department of Nuclear Medicine, University Hospital Munster, Munster, Germany
    Mini Rev Med Chem 9:1580-95. 2009
    ..This review summarizes the work that has been published in the past ten years using labeled endothelin receptor ligands for the visualization of endothelin receptor expression in vivo...
  21. ncbi request reprint [Molecular and parametric imaging with iron oxides]
    L Matuszewski
    Institut fur Klinische Radiologie, Universitatsklinikum Munster
    Radiologe 47:34-42. 2007
    ..This article provides an overview of new applications for clinically approved iron oxides as well of new, modified SPIO contrast agents for parametric and molecular imaging...
  22. ncbi request reprint [Pathomorphology of laser-induced interstitial tumor thermotherapy of the liver]
    T J Filler
    Institut fur Anatomie, Westfalische Wilhelms Universitat Munster, Vesallusweg 2 4, 48149 Munster
    Radiologe 41:181-6. 2001
    ..Ultrastructural examination revealed only in areas of minor tissue injury intact sinusoidal patterns. MRI overestimated the diameter of the core zone of complete tissue ablation both ex vivo and to a lesser extent in vivo...
  23. ncbi request reprint Hazardous situation in the MR bore: induction in ECG leads causes fire
    Harald Kugel
    Department of Clinical Radiology, University of Muenster, Albert Schweitzer Strasse 33, 48149 Muenster, Germany
    Eur Radiol 13:690-4. 2003
    ..Local heating or sparking can cause an open flame at the position of the electrodes. This danger exists even with ECG equipment that is specifically marked as MR compatible...
  24. ncbi request reprint Synthesis, in vitro pharmacology and biodistribution studies of new PD 156707-derived ET(A) receptor radioligands
    Carsten Höltke
    Department of Nuclear Medicine, Albert Schweitzer Str 33, University Hospital Munster, 48149 Munster, Germany
    Bioorg Med Chem 14:1910-7. 2006
    ..Biodistribution studies and scintigraphic imaging experiments in mice, however, showed no significant uptake of the [123I] derivative in the heart...
  25. doi request reprint Synthesis and evaluation of a novel hydroxamate based fluorescent photoprobe for imaging of matrix metalloproteinases
    Andreas Faust
    Department of Clinical Radiology, Albert Schweitzer Strasse 33, University Hospital Munster, Munster, Germany
    Bioconjug Chem 20:904-12. 2009
    ..In conclusion, this new CGS-based MMP photoprobe has a high affinity for MMP-2 and -9 and is thus a promising candidate for sensitive imaging of MMP activity in various diseases in patients...
  26. ncbi request reprint Cine and tagged magnetic resonance imaging in short-term stunned versus necrotic myocardium
    Kai Uwe Juergens
    Department of Clinical Radiology, University of Muenster, Albert Schweitzer Strasse 33, D 48149 Muenster, Germany
    Int J Cardiovasc Imaging 21:271-82. 2005
    ..Diagnostic value of ESWT is limited due to the spatial resolution of the gradient-echo sequence used...
  27. ncbi request reprint Prediction of antiangiogenic treatment efficacy by iron oxide enhanced parametric magnetic resonance imaging
    Thorsten Persigehl
    Department of Clinical Radiology, University of Munster, Munster, Germany
    Invest Radiol 42:791-6. 2007
    ....
  28. ncbi request reprint Biodistribution of a nonpeptidic fluorescent endothelin A receptor imaging probe
    Carsten Höltke
    Department of Clinical Radiology, University Hospital Muenster, Muenster, Germany
    Mol Imaging 8:27-34. 2009
    ..In conclusion, FRI allows us to perform biodistribution studies of novel fluorescent tracers. The developed imaging probe can be exploited to image ET A receptor expression ideally 30 minutes to 3 hours after injection...
  29. doi request reprint PET-compatible endothelin receptor radioligands: synthesis and first in vitro and in vivo studies
    Carsten Höltke
    Department of Nuclear Medicine, Albert Schweitzer Str 33, University Hospital Munster, D 48149 Munster, Germany
    Bioorg Med Chem 17:7197-208. 2009
    ..The biodistribution studies showed a high accumulation of the tracer in bile and intestine. In vivo we were able to show that the visualization of the heart as a major target organ with high ET(A)R expression is possible...
  30. ncbi request reprint First-pass and equilibrium-MRA of the aortoiliac region with a superparamagnetic iron oxide blood pool MR contrast agent (SH U 555 C): results of a human pilot study
    Bernd Tombach
    Department of Clinical Radiology, Westfalian Wilhelms University of Muenster, Muenster, Germany
    NMR Biomed 17:500-6. 2004
    ..SH U 555 C proved to be a contrast agent with a high T1-effect suitable for both first-pass MRA comparable to gadolinium-enhanced MRA and high resolution equilibrium MRA up to 42 min post-injection (p.i.)...
  31. doi request reprint In vivo optical imaging of CD13/APN-expression in tumor xenografts
    Angelika von Wallbrunn
    University of Munster, Department of Clinical Radiology, Waldeyerster 1, Haus Rosebach, Munster, Germany NRW 48149
    J Biomed Opt 13:011007. 2008
    ..5 combined with novel tomographic optical imaging methods allows us to image and quantify tumor-associated CD13/APN expression noninvasively. This may be a promising strategy for a sensitive evaluation of tumor angiogenesis in vivo...
  32. doi request reprint Synthesis and evaluation of a novel fluorescent photoprobe for imaging matrix metalloproteinases
    Andreas Faust
    Department of Clinical Radiology and Department of Nuclear Medicine, University Hospital Munster, Albert Schweitzer Str 33, 48149 Munster, Germany
    Bioconjug Chem 19:1001-8. 2008
    ..Therefore, this new barbiturate-based MMP-probe has a high affinity and specificity toward MMP-2 and -9 and is thus a promising candidate for sensitive MMP detection in vivo...
  33. doi request reprint Qualitative and quantitative analysis of routinely postprocessed (CLEAR) CE-MRA data sets: are SNR and CNR calculations reliable?
    Boris Buerke
    Department of Clinical Radiology, University of Muenster, Albert Schweitzer Strasse 33, 48129 Muenster, Germany
    Acad Radiol 15:1111-7. 2008
    ....
  34. ncbi request reprint Tumor blood volume determination by using susceptibility-corrected DeltaR2* multiecho MR
    Thorsten Persigehl
    Department of Clinical Radiology, University Hospital Muenster, Albert Schweitzer Str 33, D 48149 Munster, Germany
    Radiology 255:781-9. 2010
    ..To evaluate a susceptibility-corrected multiecho magnetic resonance (MR) relaxometry technique for an accurate and robust determination of DeltaR2* as a noninvasive surrogate parameter of the perfused tumor blood volume...
  35. doi request reprint Fluorescence reflectance imaging of macrophage-rich atherosclerotic plaques using an alphavbeta3 integrin-targeted fluorochrome
    Jens Waldeck
    Department of Clinical Radiology, University Hospital Muenster, University of Muenster, Muenster, Germany
    J Nucl Med 49:1845-51. 2008
    ..alphavbeta3 integrins are highly expressed by macrophages; thus, targeting alphavbeta3 may allow targeting of culprit macrophage-loaded atherosclerotic lesions in vivo...
  36. ncbi request reprint A fluorescent photoprobe for the imaging of endothelin receptors
    Carsten Höltke
    Department of Clinical Radiology, Albert Schweitzer Strasse 33, University Hospital Munster, 48149 Munster, Germany
    Bioconjug Chem 18:685-94. 2007
    ..The results suggest that the modified photoprobe tightly binds to ET(A) receptors and thus may be a possible candidate for the imaging of ET(A)R-overexpressing tissues in vivo...
  37. ncbi request reprint [Imaging of angiogenesis]
    C Bremer
    Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Boston, USA
    Radiologe 41:138-45. 2001
    ..This article intends to provide a brief overview of imaging strategies for angiogenesis and anti-angiogenic treatment...
  38. doi request reprint Endothelin-A-receptor antagonism with atrasentan exhibits limited activity on the KU-19-19 bladder cancer cell line in a mouse model
    Edwin Herrmann
    Department of Urology, University of Munster, Albert Schweitzer Strasse 33, 48149 Munster, Germany
    J Cancer Res Clin Oncol 135:1455-62. 2009
    ..In several tumor entities, the ET(A)-R plays a significant role as a drug target. In our study, we investigated whether inhibition of ET(A)-R with atrasentan leads to an antitumor effect in urinary bladder carcinoma as well...
  39. ncbi request reprint R2 and R2* mapping for sensing cell-bound superparamagnetic nanoparticles: in vitro and murine in vivo testing
    Rebecca Kuhlpeter
    Department of Clinical Radiology, University Hospital of Muenster, Albert Schweitzer Str 33, D 48129, Muenster, Germany
    Radiology 245:449-57. 2007
    ..To prospectively determine the cellular iron uptake by using R2 and R2* mapping with multiecho readout gradient-echo and spin-echo sequences...
  40. ncbi request reprint Assessment of bone marrow angiogenesis in patients with acute myeloid leukemia by using contrast-enhanced MR imaging with clinically approved iron oxides: initial experience
    Lars Matuszewski
    Department of Clinical Radiology, University of Muenster, Albert Schweitzer Str 33, D 48129 Munster, Germany
    Radiology 242:217-24. 2007
    ..To prospectively assess bone marrow (BM) angiogenesis in patients with acute myeloid leukemia (AML) by using iron oxide-enhanced magnetic resonance (MR) imaging...
  41. doi request reprint In vivo optical imaging of cellular inflammatory response in granuloma formation using fluorescence-labeled macrophages
    Michel Eisenblätter
    Department of Clinical Radiology, University Hospital of Muenster, Muenster, Germany
    J Nucl Med 50:1676-82. 2009
    ..The purpose of this study was to assess whether FRI and FMT allow for the visualization and quantification of early inflammatory processes by tracing the migration of fluorescence-labeled murine Ms in a cutaneous granuloma model...
  42. ncbi request reprint Renal tolerance of a neutral gadolinium chelate (gadobutrol) in patients with chronic renal failure: results of a randomized study
    B Tombach
    Department of Clinical Radiology, Westfalian Wilhelms University of Munster, Albert Schweitzer Str 33, Munster D 48129, Germany
    Radiology 218:651-7. 2001
    ..To assess the renal tolerance of 1.0 mol/L gadobutrol as an electrically neutral contrast agent at magnetic resonance (MR) imaging in patients with impaired renal function...
  43. ncbi request reprint In vivo imaging of gene expression:
    C Bremer
    Center for Molecular Imaging Research, Massachusetts General Hospital, Charlestown 02129, USA
    Acad Radiol 8:15-23. 2001
    ..While endeavors are under way to image targets ranging from DNA to entire phenotypes in vivo, this short review focuses on in vivo imaging of gene expression with magnetic resonance and optical techniques...
  44. ncbi request reprint Inhibition of tumor growth by RGD peptide-directed delivery of truncated tissue factor to the tumor vasculature
    Torsten Kessler
    Department of Medicine Hematology and Oncology, University of Muenster, Muenster, Germany
    Clin Cancer Res 11:6317-24. 2005
    ..This is the first report to describe the induction of selective thrombosis in tumor vessels by RGD peptide-directed delivery of tTF, which may be a promising strategy for the treatment of cancer...
  45. ncbi request reprint Detection of lymph node metastases by contrast-enhanced MRI in an experimental model
    Patrick Wunderbaldinger
    Center of Molecular Imaging Research, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Magn Reson Med 47:292-7. 2002
    ..0112 +/- 0.0061) was different from micrometastatic nodes (0.179 +/- 0.080, P < 0.00046) and nodes bearing small metastases (0.723 +/- 0.269, P < 0.00013), with high degrees of significance...
  46. ncbi request reprint Detection of dysplastic intestinal adenomas using enzyme-sensing molecular beacons in mice
    Katharina Marten
    Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02129, USA
    Gastroenterology 122:406-14. 2002
    ..Proteases play key roles in the pathogenesis of tumor growth and invasion. This study assesses the expression of cathepsin B in dysplastic adenomatous polyps...
  47. doi request reprint Infarction of tumor vessels by NGR-peptide-directed targeting of tissue factor: experimental results and first-in-man experience
    Ralf Bieker
    Departments of Medicine Hematology and Oncology, University of Muenster, Germany
    Blood 113:5019-27. 2009
    ..Targeted thrombosis in the tumor vasculature induced by tTF-NGR may be a promising strategy for the treatment of cancer...
  48. ncbi request reprint Optical imaging of matrix metalloproteinase-2 activity in tumors: feasibility study in a mouse model
    C Bremer
    Center for Molecular Imaging Research, Massachusetts General Hospital, Bldg 149, 13th St, Rm 5406, Charlestown, MA 02129, USA
    Radiology 221:523-9. 2001
    ..CONCLUSION: It is feasible to image MMP-2 enzyme activity in vivo by using near-infrared optical imaging technology and "smart" matrix metalloproteinase-sensitive probes...
  49. doi request reprint Tissue-factor fusion proteins induce occlusion of tumor vessels
    Christian Schwöppe
    Department of Medicine Hematology and Oncology, University of Muenster, Albert Schweitzer Strasse 33, Muenster, Germany
    Thromb Res 125:S143-50. 2010
    ....
  50. doi request reprint Analysis of the contrast agent Magnevist and its transmetalation products in blood plasma by capillary electrophoresis/electrospray ionization time-of-flight mass spectrometry
    Jens Künnemeyer
    Institute of Inorganic and Analytical Chemistry, University of Munster, Corrensstrasse 30, 48149 Munster, Germany
    Anal Chem 81:3600-7. 2009
    ..Transmetalation assays of Magnevist with and without supplementary iron were carried out in incubated whole blood samples...
  51. ncbi request reprint Fluorescence molecular tomography resolves protease activity in vivo
    Vasilis Ntziachristos
    Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, USA
    Nat Med 8:757-60. 2002
    ....
  52. ncbi request reprint Oligomerization of paramagnetic substrates result in signal amplification and can be used for MR imaging of molecular targets
    Alexei Bogdanov
    Center for Molecular Imaging Research, Massachusetts General Hospital, CNY 5, Rm 5420, Building 149, 13th Street, Charlestown, MA 02129, USA
    Mol Imaging 1:16-23. 2002
    ..One particular advantage of the MRamp technique is that the same paramagnetic substrate can be potentially used to identify different molecular targets by attaching enzymes to various antibodies or other target-seeking molecules...
  53. doi request reprint Optical techniques for the molecular imaging of angiogenesis
    Michel Eisenblätter
    Department of Clinical Radiology, University Hospital Munster, Germany
    Eur J Nucl Med Mol Imaging 37:S127-37. 2010
    ..Different imaging modalities as well as various optical contrast agents are briefly discussed...
  54. ncbi request reprint Chemotherapy in metastatic malignant triton tumor: report on two cases
    N H Thoennissen
    Department of Medicine, Hematology and Oncology, University of Munster, D 48149 Munster, Germany
    Oncol Rep 18:763-7. 2007
    ..In both cases, integrated Positron Emission Tomography/Computed Tomography (PET/CT) emerged as an important diagnostic tool for the reliable assessment of MTT response and metabolic remission...
  55. ncbi request reprint Clinical molecular imaging in intestinal graft-versus-host disease: mapping of disease activity, prediction, and monitoring of treatment efficiency by positron emission tomography
    Matthias Stelljes
    Department of Medicine Hematology and Oncology, University of Muenster, Albert Schweitzer Strasse 33, Muenster, Germany
    Blood 111:2909-18. 2008
    ..Novel targeted tracers for PET may provide new insights into the pathophysiology of GVHD and bear the potential to further improve GVHD diagnosis...
  56. ncbi request reprint Using highly concentrated gadobutrol as an MR contrast agent in patients also requiring hemodialysis: safety and dialysability
    Bernd Tombach
    Department of Clinical Radiology, Westfalian Wilhelms University of Muenster, Albert Schweitzer Str 33, D 48129 Munster, Germany
    AJR Am J Roentgenol 178:105-9. 2002
    ..The purpose of our study was to assess the safety and dialysability of gadobutrol, a new, electrically neutral, and highly concentrated MR contrast agent, in patients who require hemodialysis...
  57. ncbi request reprint Cell tagging with clinically approved iron oxides: feasibility and effect of lipofection, particle size, and surface coating on labeling efficiency
    Lars Matuszewski
    Department of Clinical Radiology, University Hospital Muenster, Albert Schweitzer Strasse 33, D 48129 Muenster, Germany
    Radiology 235:155-61. 2005
    ..To evaluate the effect of lipofection, particle size, and surface coating on labeling efficiency of mammalian cells with superparamagnetic iron oxides (SPIOs)...
  58. ncbi request reprint Near-infrared fluorescence imaging of lymph nodes using a new enzyme sensing activatable macromolecular optical probe
    Patrick Wunderbaldinger
    Department of Radiology, University of Vienna, Waehringer Guertel 18 20, 1090 Vienna, Austria
    Eur Radiol 13:2206-11. 2003
    ..c. injection (6.6%+/-0.81) compared with i.v. injection (4.8+/-0.67%). Detection and visualization of lymph nodes is feasible by NIRF imaging using a cystein-protease sensitive optical probe...
  59. ncbi request reprint Myocardial perfusion and MR angiography of chest with SH U 555 C: results of placebo-controlled clinical phase i study
    Peter Reimer
    Department of Radiology, Stadtisches Klinikum Karlsruhe, Academic Teaching Hospital of University of Freiburg, Moltkestrasse 90, D 76133 Karlsruhe, Germany
    Radiology 231:474-81. 2004
    ..To evaluate SH U 555 C for contrast material-enhanced three-dimensional magnetic resonance (MR) angiography of the chest and myocardial perfusion...