Fank Brasch

Summary

Country: Germany

Publications

  1. ncbi HNPCC: six new pathogenic mutations
    Erdmute Kunstmann
    Human Genetics, University of Bochum, Bochum, Germany
    BMC Med Genet 5:16. 2004
  2. ncbi Involvement of cathepsin H in the processing of the hydrophobic surfactant-associated protein C in type II pneumocytes
    Frank Brasch
    Division of Electron Microscopy, Department of Anatomy, University of Gottingen, Germany
    Am J Respir Cell Mol Biol 26:659-70. 2002
  3. ncbi Surfactant protein B in type II pneumocytes and intra-alveolar surfactant forms of human lungs
    Frank Brasch
    Department of Anatomy, University of Gottingen, Gottingen, Germany
    Am J Respir Cell Mol Biol 30:449-58. 2004
  4. ncbi Involvement of napsin A in the C- and N-terminal processing of surfactant protein B in type-II pneumocytes of the human lung
    Frank Brasch
    Department of Anatomy, University of Gottingen, Kreuzbergring 36, D 37075 Gottingen, Germany
    J Biol Chem 278:49006-14. 2003
  5. ncbi [Classification of pulmonary alveolar proteinosis in newborns, infants, and children]
    F Brasch
    Institut fur Pathologie, Berufsgenossenschaftliche Kliniken Bergmannsheil Bochum
    Pathologe 25:299-309. 2004
  6. ncbi Interstitial lung disease in a baby with a de novo mutation in the SFTPC gene
    F Brasch
    Institute of Pathology, University Hospital Bergmannsheil, Bochum, Germany
    Eur Respir J 24:30-9. 2004
  7. ncbi Surfactant proteins in pulmonary alveolar proteinosis in adults
    F Brasch
    Institute of Pathology, University Hospital Bergmannsheil, Buerkle de la Camp Platz 1, D 44789, Bochum, Germany
    Eur Respir J 24:426-35. 2004
  8. ncbi [Rare pulmonary occupational diseases--importance of microanalytical examination]
    Fank Brasch
    Institut fur Pathologie, Berufsgenossenschaftliche Kliniken Bergmannsheil, Universitätsklinik Ruhr Universität Bochum, Bochum, Deutschland
    Wien Klin Wochenschr 116:18-24. 2004
  9. ncbi Adult polyglucosan body disease: a postmortem correlation study
    E Sindern
    Department of Neurology, BG Kliniken Bergmannsheil, Ruhr University, Bochum, Germany
    Neurology 61:263-5. 2003

Collaborators

Detail Information

Publications9

  1. ncbi HNPCC: six new pathogenic mutations
    Erdmute Kunstmann
    Human Genetics, University of Bochum, Bochum, Germany
    BMC Med Genet 5:16. 2004
    ..HNPCC accounts for approximately 2 to 5% of all colorectal cancers. Here we present 6 novel mutations in the DNA mismatch-repair genes MLH1, MSH2 and MSH6...
  2. ncbi Involvement of cathepsin H in the processing of the hydrophobic surfactant-associated protein C in type II pneumocytes
    Frank Brasch
    Division of Electron Microscopy, Department of Anatomy, University of Gottingen, Germany
    Am J Respir Cell Mol Biol 26:659-70. 2002
    ....
  3. ncbi Surfactant protein B in type II pneumocytes and intra-alveolar surfactant forms of human lungs
    Frank Brasch
    Department of Anatomy, University of Gottingen, Gottingen, Germany
    Am J Respir Cell Mol Biol 30:449-58. 2004
    ..In human lungs, mature SP-B is involved in the structural organization of lamellar bodies and tubular myelin by the formation of core particles...
  4. ncbi Involvement of napsin A in the C- and N-terminal processing of surfactant protein B in type-II pneumocytes of the human lung
    Frank Brasch
    Department of Anatomy, University of Gottingen, Kreuzbergring 36, D 37075 Gottingen, Germany
    J Biol Chem 278:49006-14. 2003
    ..Two of the four processing products generated in vitro were also detected in type-II pneumocytes. In conclusion, our results show that napsin A is involved in the N- and C-terminal processing of proSP-B in type-II pneumocytes...
  5. ncbi [Classification of pulmonary alveolar proteinosis in newborns, infants, and children]
    F Brasch
    Institut fur Pathologie, Berufsgenossenschaftliche Kliniken Bergmannsheil Bochum
    Pathologe 25:299-309. 2004
    ....
  6. ncbi Interstitial lung disease in a baby with a de novo mutation in the SFTPC gene
    F Brasch
    Institute of Pathology, University Hospital Bergmannsheil, Bochum, Germany
    Eur Respir J 24:30-9. 2004
    ..This report heralds the emerging diversity of phenotypes associated with the expression of mutant surfactant C proteins...
  7. ncbi Surfactant proteins in pulmonary alveolar proteinosis in adults
    F Brasch
    Institute of Pathology, University Hospital Bergmannsheil, Buerkle de la Camp Platz 1, D 44789, Bochum, Germany
    Eur Respir J 24:426-35. 2004
    ....
  8. ncbi [Rare pulmonary occupational diseases--importance of microanalytical examination]
    Fank Brasch
    Institut fur Pathologie, Berufsgenossenschaftliche Kliniken Bergmannsheil, Universitätsklinik Ruhr Universität Bochum, Bochum, Deutschland
    Wien Klin Wochenschr 116:18-24. 2004
    ..Using the example of silver finisher's lung, dental technician's lung and talcosis, the connections between foreign particle deposits in lung tissue and granulomatous and fibrosing pulmonary changes are shown...
  9. ncbi Adult polyglucosan body disease: a postmortem correlation study
    E Sindern
    Department of Neurology, BG Kliniken Bergmannsheil, Ruhr University, Bochum, Germany
    Neurology 61:263-5. 2003
    ..GBE activity was decreased in the morphologically affected tissues but was normal in unaffected tissues. GBE mRNA transcripts were similar in all tissues and in controls, which confirms the lack of tissue-specific GBE isoforms...