Katarzyna Bozek

Summary

Country: Germany

Publications

  1. ncbi V3 loop sequence space analysis suggests different evolutionary patterns of CCR5- and CXCR4-tropic HIV
    Katarzyna Bozek
    Max Planck Institute for Informatics, Saarbrucken, Germany
    PLoS ONE 4:e7387. 2009
  2. ncbi A single amino acid substitution of the human immunodeficiency virus type 1 capsid protein affects viral sensitivity to TRIM5 alpha
    Ayumu Kuroishi
    Department of Viral Infections, Research Institute for Microbial Diseases, Osaka University, Osaka 565 0871, Japan
    Retrovirology 7:58. 2010
  3. ncbi Positive selection of HIV host factors and the evolution of lentivirus genes
    Katarzyna Bozek
    Max Planck Institute for Informatics Computational Biology and Applied Algorithmics, Campus E1 4, 66123 SaarbrA 1 4 cken, Germany
    BMC Evol Biol 10:186. 2010
  4. ncbi An expanded model of HIV cell entry phenotype based on multi-parameter single-cell data
    Katarzyna Bozek
    Department of Computational Biology and Applied Algorithmics, Max Planck for Computer Sciences, Campus E1 4 66123, Saarbrucken, Germany
    Retrovirology 9:60. 2012
  5. ncbi Analysis of Physicochemical and Structural Properties Determining HIV-1 Coreceptor Usage
    Katarzyna Bozek
    Max Planck Institute for Computer Science, Saarbrucken, Germany
    PLoS Comput Biol 9:e1002977. 2013

Collaborators

Detail Information

Publications5

  1. ncbi V3 loop sequence space analysis suggests different evolutionary patterns of CCR5- and CXCR4-tropic HIV
    Katarzyna Bozek
    Max Planck Institute for Informatics, Saarbrucken, Germany
    PLoS ONE 4:e7387. 2009
    ..Our study thus supports hypotheses of an association of immune system depletion with an increase in V3 loop sequence variability and with the escape of the viral sequence to distant parts of the sequence space...
  2. ncbi A single amino acid substitution of the human immunodeficiency virus type 1 capsid protein affects viral sensitivity to TRIM5 alpha
    Ayumu Kuroishi
    Department of Viral Infections, Research Institute for Microbial Diseases, Osaka University, Osaka 565 0871, Japan
    Retrovirology 7:58. 2010
    ..This virus (NL-4/5S6/7SvifS) was supposed to escape from host restriction factors cyclophilin A, CM TRIM5 alpha, and APOBEC3G. However, the replicative capability of NL-4/5S6/7SvifS in human cells was severely impaired...
  3. ncbi Positive selection of HIV host factors and the evolution of lentivirus genes
    Katarzyna Bozek
    Max Planck Institute for Informatics Computational Biology and Applied Algorithmics, Campus E1 4, 66123 SaarbrA 1 4 cken, Germany
    BMC Evol Biol 10:186. 2010
    ..Positive selection of host proteins that interact with pathogens can indicate factors relevant for infection and potentially be a measure of pathogen driven evolution...
  4. ncbi An expanded model of HIV cell entry phenotype based on multi-parameter single-cell data
    Katarzyna Bozek
    Department of Computational Biology and Applied Algorithmics, Max Planck for Computer Sciences, Campus E1 4 66123, Saarbrucken, Germany
    Retrovirology 9:60. 2012
    ....
  5. ncbi Analysis of Physicochemical and Structural Properties Determining HIV-1 Coreceptor Usage
    Katarzyna Bozek
    Max Planck Institute for Computer Science, Saarbrucken, Germany
    PLoS Comput Biol 9:e1002977. 2013
    ..These regions are in close proximity in the bound conformation of the loop potentially forming a site determinant for the coreceptor binding. The method is available via server under http://structure.bioinf.mpi-inf.mpg.de/...