Jan Borgel

Summary

Country: Germany

Publications

  1. ncbi request reprint Obstructive sleep apnea and blood pressure. Interaction between the blood pressure-lowering effects of positive airway pressure therapy and antihypertensive drugs
    Jan Borgel
    Medical Clinic II, Cardiology and Angiology, St Josef Hospital Bergmannsheil, Ruhr University Bochum, 44791 Bochum, Germany
    Am J Hypertens 17:1081-7. 2004
  2. ncbi request reprint Modifying effects of the R389G beta1-adrenoceptor polymorphism on resting heart rate and blood pressure in patients with obstructive sleep apnoea
    Jan Borgel
    Medical Clinic 2, Cardiology and Angiology, St Josef Hospital Bergmannsheil, Ruhr University, Bochum, Germany
    Clin Sci (Lond) 110:117-23. 2006
  3. ncbi request reprint Obstructive sleep apnoea and its therapy influence high-density lipoprotein cholesterol serum levels
    J Borgel
    Dept of Medicine, Cardiology and Angiology, St Josef Hospital Bergmannsheil, Gudrunstrasse 56, 44791 Bochum, Germany
    Eur Respir J 27:121-7. 2006
  4. pmc The CYP2J2 G-50T polymorphism and myocardial infarction in patients with cardiovascular risk profile
    Jan Borgel
    Department of Cardiology, St, Josef Hospital Bergmannsheil, Ruhr University, Bochum, Germany
    BMC Cardiovasc Disord 8:41. 2008
  5. pmc Risk factors and myocardial infarction in patients with obstructive sleep apnea: impact of beta2-adrenergic receptor polymorphisms
    Nina K Bartels
    Human Genetics, Ruhr University Bochum, Germany
    BMC Med 5:1. 2007
  6. doi request reprint Circulating endothelial microparticles correlate inversely with endothelial function in patients with ischemic left ventricular dysfunction
    Daniel Bulut
    Herzzentrum der Kliniken der Ruhr Universität Bochum, Standort St Josef Hospital, Gudrunstrasse 56, 44791 Bochum, Germany
    J Card Fail 14:336-40. 2008
  7. doi request reprint Upregulation of platelet CD40, CD40 ligand (CD40L) and P-Selectin expression in cigarette smokers: a flow cytometry study
    Horst Neubauer
    Cardiovascular Center, Ruhr University Bochum, Germany
    Blood Coagul Fibrinolysis 20:694-8. 2009
  8. doi request reprint Pantoprazole does not influence the antiplatelet effect of clopidogrel-a whole blood aggregometry study after coronary stenting
    Horst Neubauer
    Ruhr University Bochum, Cardiovascular Center, St Josef Hospital, Bochum, Germany
    J Cardiovasc Pharmacol 56:91-7. 2010
  9. doi request reprint Images in cardiovascular medicine. Central sleep apnea induces ventricular bigeminus: conclusions from a single polygraphy
    Jan Borgel
    Department of Cardiology, St Josef Hospital Bergmannsheil, University of Bochum, Bochum, Germany
    Circulation 118:1398-401. 2008
  10. ncbi request reprint Hormonal status modulates circulating endothelial progenitor cells
    Daniel Bulut
    Division of Cardiology, St Josef Hospital, Ruhr University Bochum, Gudrunstrasse 56, 44791, Bochum, Germany
    Clin Res Cardiol 96:258-63. 2007

Collaborators

Detail Information

Publications14

  1. ncbi request reprint Obstructive sleep apnea and blood pressure. Interaction between the blood pressure-lowering effects of positive airway pressure therapy and antihypertensive drugs
    Jan Borgel
    Medical Clinic II, Cardiology and Angiology, St Josef Hospital Bergmannsheil, Ruhr University Bochum, 44791 Bochum, Germany
    Am J Hypertens 17:1081-7. 2004
    ..Previous studies on the antihypertensive effects of positive airway pressure therapy on daytime blood pressure (BP) revealed inconsistent results...
  2. ncbi request reprint Modifying effects of the R389G beta1-adrenoceptor polymorphism on resting heart rate and blood pressure in patients with obstructive sleep apnoea
    Jan Borgel
    Medical Clinic 2, Cardiology and Angiology, St Josef Hospital Bergmannsheil, Ruhr University, Bochum, Germany
    Clin Sci (Lond) 110:117-23. 2006
    ..2) beats/min for G389G]. In conclusion, although the R389G polymorphism of the beta1-adrenoceptor gene did not influence resting HR or BP in untreated OSA patients, it may modify the beneficial effects of CPAP therapy on these parameters...
  3. ncbi request reprint Obstructive sleep apnoea and its therapy influence high-density lipoprotein cholesterol serum levels
    J Borgel
    Dept of Medicine, Cardiology and Angiology, St Josef Hospital Bergmannsheil, Gudrunstrasse 56, 44791 Bochum, Germany
    Eur Respir J 27:121-7. 2006
    ..This study demonstrates an influence of obstructive sleep apnoea and its therapy on high-density lipoprotein cholesterol levels...
  4. pmc The CYP2J2 G-50T polymorphism and myocardial infarction in patients with cardiovascular risk profile
    Jan Borgel
    Department of Cardiology, St, Josef Hospital Bergmannsheil, Ruhr University, Bochum, Germany
    BMC Cardiovasc Disord 8:41. 2008
    ..In the present study, we investigated the influence of this polymorphism on survived myocardial infarction in two study groups of patients with on average high cardiovascular risk profile...
  5. pmc Risk factors and myocardial infarction in patients with obstructive sleep apnea: impact of beta2-adrenergic receptor polymorphisms
    Nina K Bartels
    Human Genetics, Ruhr University Bochum, Germany
    BMC Med 5:1. 2007
    ..The functionally relevant polymorphisms of the beta2-adrenergic receptor (Arg-47Cys/Arg16Gly and Gln27Glu) have been shown to exert modifying effects on these risk factors in previous studies, but results are inconsistent...
  6. doi request reprint Circulating endothelial microparticles correlate inversely with endothelial function in patients with ischemic left ventricular dysfunction
    Daniel Bulut
    Herzzentrum der Kliniken der Ruhr Universität Bochum, Standort St Josef Hospital, Gudrunstrasse 56, 44791 Bochum, Germany
    J Card Fail 14:336-40. 2008
    ..The patients were divided in 2 groups, those with preserved or normal function (n = 17; EF 65 +/- 6%) and those with reduced left ventricular (LV) function (n = 18; EF 36 +/- 11%)...
  7. doi request reprint Upregulation of platelet CD40, CD40 ligand (CD40L) and P-Selectin expression in cigarette smokers: a flow cytometry study
    Horst Neubauer
    Cardiovascular Center, Ruhr University Bochum, Germany
    Blood Coagul Fibrinolysis 20:694-8. 2009
    ..These findings emphasize that cigarette smoking leads to a proinflammatory and prothrombotic state thus contributing to accelerated atherosclerosis...
  8. doi request reprint Pantoprazole does not influence the antiplatelet effect of clopidogrel-a whole blood aggregometry study after coronary stenting
    Horst Neubauer
    Ruhr University Bochum, Cardiovascular Center, St Josef Hospital, Bochum, Germany
    J Cardiovasc Pharmacol 56:91-7. 2010
    ..Therefore, the use of pantoprazole seems preferable in patients treated with clopidogrel when a concomitant medication with a PPI is indicated...
  9. doi request reprint Images in cardiovascular medicine. Central sleep apnea induces ventricular bigeminus: conclusions from a single polygraphy
    Jan Borgel
    Department of Cardiology, St Josef Hospital Bergmannsheil, University of Bochum, Bochum, Germany
    Circulation 118:1398-401. 2008
  10. ncbi request reprint Hormonal status modulates circulating endothelial progenitor cells
    Daniel Bulut
    Division of Cardiology, St Josef Hospital, Ruhr University Bochum, Gudrunstrasse 56, 44791, Bochum, Germany
    Clin Res Cardiol 96:258-63. 2007
    ..Endothelial progenitor cells (EPCs) may have an important role in vascular homeostasis and repair...
  11. ncbi request reprint Doppler echocardiographic prediction of recurrent atrial fibrillation following cardioversion
    Martin Spiecker
    Heart and Vascular Center Bochum, Department of Medicine II Cardiology, St Josef Hospital, University of Bochum, Gudrunstrasse 56, 44791 Bochum, Germany
    Int J Cardiol 113:161-6. 2006
    ..Measuring atrial mechanical function is of interest to determine the individual risk of thromboembolism and the risk of recurrent AF...
  12. ncbi request reprint Continuous positive airway pressure treatment of mild to moderate obstructive sleep apnea reduces cardiovascular risk
    Nikolaus J Buchner
    Department of Internal Medicine I, Marienhospital Herne, Ruhr University Bochum, Hoelkeskampring 40, D 44625 Herne, Germany
    Am J Respir Crit Care Med 176:1274-80. 2007
    ..Obstructive sleep apnea (OSA) is linked to increased cardiovascular risk, but the impact of mild forms of OSA and their treatment on cardiovascular outcomes remains controversial...
  13. pmc Risk of coronary artery disease associated with polymorphism of the cytochrome P450 epoxygenase CYP2J2
    Martin Spiecker
    Department of Medicine II Cardiology, St Josef Hospital, University of Bochum, Gudrunstr 56, 44791 Bochum, Germany
    Circulation 110:2132-6. 2004
    ..The EETs are potent endogenous vasodilators and inhibitors of vascular inflammation. However, it is not known whether genetic polymorphisms of CYP2J2 are associated with increased cardiovascular risks...
  14. doi request reprint Effect of protein A immunoadsorption on T cell activation in patients with inflammatory dilated cardiomyopathy
    Daniel Bulut
    Herz und Kreislaufzentrum der Ruhr Universität, Standort St Josef Hospital, Bochum, Germany
    Clin Res Cardiol 99:633-8. 2010
    ..Changes in cell-mediated immunity after IA may contribute to this observation. The aim of this study is to investigate the effect of IA on cell-mediated immunity especially on regulatory and early activated T cells...