E Bonifacio

Summary

Country: Germany

Publications

  1. pmc An interferon-induced helicase (IFIH1) gene polymorphism associates with different rates of progression from autoimmunity to type 1 diabetes
    Christiane Winkler
    Forschergruppe Diabetes e V at Helmholtz Center Munich, Neuherberg, Germany
    Diabetes 60:685-90. 2011
  2. ncbi request reprint A strategy to find gene combinations that identify children who progress rapidly to type 1 diabetes after islet autoantibody seroconversion
    Ezio Bonifacio
    Center for Regenerative Therapies Dresden, Technische Universitat Dresden, Fetscherstrasse 105, 01307, Dresden, Germany
    Acta Diabetol 51:403-11. 2014
  3. pmc The use of biomaterials in islet transplantation
    Danielle J Borg
    Preclinical Approaches to Stem Cell Therapy Diabetes, Technische Universitat Dresden, DFG Center for Regenerative Therapies Dresden, Cluster of Excellence, Tatzberg 47 49, 01307 Dresden, Germany
    Curr Diab Rep 11:434-44. 2011
  4. doi request reprint Mucosal insulin vaccination for type 1 diabetes prevention
    E Bonifacio
    CRTD, Dresden University of Technology, Dresden, Germany
    Exp Clin Endocrinol Diabetes 116:S26-9. 2008
  5. doi request reprint Advances in the prediction and natural history of type 1 diabetes
    Ezio Bonifacio
    Deutsche Forschungsgemeinschaft Center for Regenerative Therapies Dresden, Technische Universitat Dresden, Tatzberg 47 49, 01307 Dresden, Germany
    Endocrinol Metab Clin North Am 39:513-25. 2010
  6. pmc Harmonization of glutamic acid decarboxylase and islet antigen-2 autoantibody assays for national institute of diabetes and digestive and kidney diseases consortia
    Ezio Bonifacio
    Deutsche Forschungsgemeinschaft Center for Regenerative Therapies, 01307 Dresden, Germany
    J Clin Endocrinol Metab 95:3360-7. 2010
  7. pmc Insulin autoantibodies with high affinity to the bovine milk protein alpha casein
    K Adler
    Diabetes Research Institute, Forschergruppe Diabetes e V, Munich Center for Regenerative Therapies Dresden, Dresden University of Technology, Dresden, Germany
    Clin Exp Immunol 164:42-9. 2011
  8. doi request reprint Autoantibodies to zinc transporter 8 and SLC30A8 genotype stratify type 1 diabetes risk
    P Achenbach
    Diabetes Research Institute of Forschergruppe Diabetes e V, Helmholtz Center Munich, Ingolstaedter Landstr 1, 85764, Neuherberg, Germany
    Diabetologia 52:1881-8. 2009
  9. doi request reprint Endocrine autoimmunity in families with type 1 diabetes: frequent appearance of thyroid autoimmunity during late childhood and adolescence
    E Bonifacio
    DFG Research Center and Cluster of Excellence for Regenerative Therapies Dresden, Dresden University of Technology, Dresden, Germany
    Diabetologia 52:185-92. 2009
  10. doi request reprint Is islet autoimmunity related to insulin sensitivity or body weight in children of parents with type 1 diabetes?
    C Winkler
    Institut für Diabetesforschung der Forschergruppe Diabetes e V, Helmholtz Center Munich, Neuherberg, Germany
    Diabetologia 52:2072-8. 2009

Collaborators

  • A G Ziegler
  • Thomas Illig
  • M Solimena
  • M Hanefeld
  • Liping Yu
  • P E H Schwarz
  • Polly J Bingley
  • K Adler
  • Y F Fuchs
  • S Krause
  • P Achenbach
  • C Winkler
  • Christiane Winkler
  • Danielle J Borg
  • M Reimann
  • M Weigelt
  • L F Mortler-Hildebrandt
  • A Lindner
  • H Balke
  • K Förtsch
  • K Pechhold
  • C Wilhelm
  • A Karasinsky
  • D M Harlan
  • K Foertsch
  • Claudia Lauber
  • D B Mueller
  • Harald Grallert
  • A K Heninger
  • Kerstin Adler
  • K Koczwara
  • S R Bornstein
  • H Grallert
  • V Lampasona
  • S Marienfeld
  • B Ludwig
  • M Pflüger
  • U Landherr
  • M Zwilling

Detail Information

Publications14

  1. pmc An interferon-induced helicase (IFIH1) gene polymorphism associates with different rates of progression from autoimmunity to type 1 diabetes
    Christiane Winkler
    Forschergruppe Diabetes e V at Helmholtz Center Munich, Neuherberg, Germany
    Diabetes 60:685-90. 2011
    ..The aim of this study was to determine whether these associations are with the development of autoimmunity and/or progression to diabetes...
  2. ncbi request reprint A strategy to find gene combinations that identify children who progress rapidly to type 1 diabetes after islet autoantibody seroconversion
    Ezio Bonifacio
    Center for Regenerative Therapies Dresden, Technische Universitat Dresden, Fetscherstrasse 105, 01307, Dresden, Germany
    Acta Diabetol 51:403-11. 2014
    ..These findings highlight genes that may affect the rate of the beta-cell destruction process once autoimmunity has initiated and may help to identify islet autoantibody-positive subjects with rapid progression to diabetes. ..
  3. pmc The use of biomaterials in islet transplantation
    Danielle J Borg
    Preclinical Approaches to Stem Cell Therapy Diabetes, Technische Universitat Dresden, DFG Center for Regenerative Therapies Dresden, Cluster of Excellence, Tatzberg 47 49, 01307 Dresden, Germany
    Curr Diab Rep 11:434-44. 2011
    ..Here we review the application of niche accessory cells and factors, as well as the use of biomaterials as carriers or capsules, for pancreatic islet transplantation...
  4. doi request reprint Mucosal insulin vaccination for type 1 diabetes prevention
    E Bonifacio
    CRTD, Dresden University of Technology, Dresden, Germany
    Exp Clin Endocrinol Diabetes 116:S26-9. 2008
    ..Here we address these issues and propose a clinical translation possibility for mucosal insulin administration in genetically at risk individuals...
  5. doi request reprint Advances in the prediction and natural history of type 1 diabetes
    Ezio Bonifacio
    Deutsche Forschungsgemeinschaft Center for Regenerative Therapies Dresden, Technische Universitat Dresden, Tatzberg 47 49, 01307 Dresden, Germany
    Endocrinol Metab Clin North Am 39:513-25. 2010
    ..This article reviews these biomarkers and T1D prediction strategies, and discusses potential implications of prediction and natural history for the pathogenesis of T1D...
  6. pmc Harmonization of glutamic acid decarboxylase and islet antigen-2 autoantibody assays for national institute of diabetes and digestive and kidney diseases consortia
    Ezio Bonifacio
    Deutsche Forschungsgemeinschaft Center for Regenerative Therapies, 01307 Dresden, Germany
    J Clin Endocrinol Metab 95:3360-7. 2010
    ..A harmonization program was established to increase comparability of results within and among these studies...
  7. pmc Insulin autoantibodies with high affinity to the bovine milk protein alpha casein
    K Adler
    Diabetes Research Institute, Forschergruppe Diabetes e V, Munich Center for Regenerative Therapies Dresden, Dresden University of Technology, Dresden, Germany
    Clin Exp Immunol 164:42-9. 2011
    ..These results suggest that autoimmunity to insulin can occur infrequently via cross-reactivity to food proteins, but this form of IAA immunization does not appear to be associated with progression to diabetes...
  8. doi request reprint Autoantibodies to zinc transporter 8 and SLC30A8 genotype stratify type 1 diabetes risk
    P Achenbach
    Diabetes Research Institute of Forschergruppe Diabetes e V, Helmholtz Center Munich, Ingolstaedter Landstr 1, 85764, Neuherberg, Germany
    Diabetologia 52:1881-8. 2009
    ..Our aim was to determine the relationships between autoantibodies to zinc transporter 8 (ZnT8), genotypes of the ZnT8-encoding gene SLC30A8 and type 1 diabetes risk...
  9. doi request reprint Endocrine autoimmunity in families with type 1 diabetes: frequent appearance of thyroid autoimmunity during late childhood and adolescence
    E Bonifacio
    DFG Research Center and Cluster of Excellence for Regenerative Therapies Dresden, Dresden University of Technology, Dresden, Germany
    Diabetologia 52:185-92. 2009
    ..The aim of this study was to determine the chronological appearance of thyroid autoantibodies in relation to other forms of autoimmunity in at-risk children...
  10. doi request reprint Is islet autoimmunity related to insulin sensitivity or body weight in children of parents with type 1 diabetes?
    C Winkler
    Institut für Diabetesforschung der Forschergruppe Diabetes e V, Helmholtz Center Munich, Neuherberg, Germany
    Diabetologia 52:2072-8. 2009
    ..The aim of the present study was to determine whether insulin demand is increased in children with islet autoantibodies...
  11. ncbi request reprint IGRP and insulin vaccination induce CD8+ T cell-mediated autoimmune diabetes in the RIP-CD80GP mouse
    Y F Fuchs
    DFG Center for Regenerative Therapies Dresden CRTD, Technische Universitat Dresden, Dresden, Germany Paul Langerhans Institute Dresden German Center for Diabetes Research DZD, Dresden, Germany
    Clin Exp Immunol 176:199-206. 2014
    ..We conclude that RIP-CD80GP mice are a versatile model of antigen specific autoimmune diabetes and may complement existing mouse models of autoimmune diabetes for evaluating CD8(+) T cell-targeted prevention strategies. ..
  12. pmc The effect of gestation and fetal mismatching on the development of autoimmune diabetes in non-obese diabetic mice
    K Adler
    Diabetes Research Institute, Forschergruppe Diabetes e V, Munich, Germany
    Clin Exp Immunol 168:274-8. 2012
    ..Gestation per se appears to have no aggravating or ameliorating effects on pre-existent autoimmune beta cell destruction, but pregnancy from MHC partially mismatched males delays diabetes onset in female NOD mice...
  13. ncbi request reprint An update on preventive and regenerative therapies in diabetes mellitus
    M Reimann
    Department of Internal Medicine III, Medical Faculty Carl Gustav Carus, Dresden University of Technology, Dresden, Germany
    Pharmacol Ther 121:317-31. 2009
    ..Lastly, important efforts to halt disease progression with emphasis on beta-cell regeneration are presented...