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..In conclusion, carboplatin single agent therapy cannot be recommended as standard treatment for any patient subgroup with advanced metastatic seminoma and cisplatin-based combination regimens remain the standard of care. ..
Bokemeyer C, Kollmannsberger C, Harstrick A, Beyer J, Gerl A, Casper J, et al
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..Future trials combining new active agents may examine alternating treatment strategies in patients with poor-prognostic disease or as salvage treatment. ..
Bokemeyer C, Gillis A, Pompe K, Mayer F, Metzner B, Schleucher N, et al
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..Factors such as responsiveness to chemotherapy and tumor mass seem to overcome the importance of potentially re-infused tumor cells. ..
Bokemeyer C, Kollmannsberger C, Oechsle K, Dohmen B, Pfannenberg A, Claussen C, et al
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..It may also be a valuable addition to the prognostic model particularly in the good and intermediate group for further selection of patients who will profit from high-dose chemotherapy. ..
Bokemeyer C, Nichols C, Droz J, Schmoll H, Horwich A, Gerl A, et al
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..This outcome is clearly inferior compared with patients with nonseminomatous retroperitoneal primary tumors. ..
Bokemeyer C, Hartmann J, Fossa S, Droz J, Schmol H, Horwich A, et al
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..Patients with mediastinal nonseminomas have a five-years survival rate of 45%. This outcome is clearly inferior compared to patients with nonseminomatous retroperitoneal primaries who have a five-year survival rate of 62%. ..