Carmen Birchmeier

Summary

Country: Germany

Publications

  1. pmc A dual role of erbB2 in myelination and in expansion of the schwann cell precursor pool
    A N Garratt
    Max Delbrück Centrum for Molecular Medicine, 13125 Berlin, Germany
    J Cell Biol 148:1035-46. 2000
  2. ncbi request reprint Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase
    C Birchmeier
    Dept of Medical Genetics, Max Delbrück Centrum for Molecular Medicine, Berlin, Germany
    Trends Cell Biol 8:404-10. 1998
  3. ncbi request reprint Genes that control the development of migrating muscle precursor cells
    C Birchmeier
    Max Delbrueck Centre for Molecular Medicine, Robert Roessle Strasse 10, 13092, Berlin, Germany
    Curr Opin Cell Biol 12:725-30. 2000
  4. doi request reprint ErbB receptors and the development of the nervous system
    Carmen Birchmeier
    Max Delbrueck Centrum, Robert Roessle Strasse 10, D 13125 Berlin Buch, Germany
    Exp Cell Res 315:611-8. 2009
  5. doi request reprint Neuregulin-1, a key axonal signal that drives Schwann cell growth and differentiation
    Carmen Birchmeier
    Max Delbrueck Centrum, Robert Roessle Strasse 10, Berlin Buch, Germany
    Glia 56:1491-7. 2008
  6. doi request reprint The bHLH transcription factor Olig3 marks the dorsal neuroepithelium of the hindbrain and is essential for the development of brainstem nuclei
    Robert Storm
    Max Delbrück Centrum for Molecular Medicine, Robert Rossle Strasse 10, 13125 Berlin, Germany
    Development 136:295-305. 2009
  7. doi request reprint A transcriptional network coordinately determines transmitter and peptidergic fate in the dorsal spinal cord
    Dominique Bröhl
    Department of Neuroscience, Max Delbrück Centrum for Molecular Medicine, Berlin, Germany
    Dev Biol 322:381-93. 2008
  8. ncbi request reprint Insm1 (IA-1) is a crucial component of the transcriptional network that controls differentiation of the sympatho-adrenal lineage
    Hendrik Wildner
    Max Delbrück Centrum for Molecular Medicine, Robert Rossle Strasse 10, 13125 Berlin, Germany
    Development 135:473-81. 2008
  9. ncbi request reprint Lbx1 acts as a selector gene in the fate determination of somatosensory and viscerosensory relay neurons in the hindbrain
    Martin A Sieber
    Department of Neuroscience, Max Delbruck Center for Molecular Medicine, Berlin, Germany
    J Neurosci 27:4902-9. 2007
  10. ncbi request reprint dILA neurons in the dorsal spinal cord are the product of terminal and non-terminal asymmetric progenitor cell divisions, and require Mash1 for their development
    Hendrik Wildner
    Max Delbrück Centrum for Molecular Medicine, Berlin Buch, Germany
    Development 133:2105-13. 2006

Collaborators

Detail Information

Publications18

  1. pmc A dual role of erbB2 in myelination and in expansion of the schwann cell precursor pool
    A N Garratt
    Max Delbrück Centrum for Molecular Medicine, 13125 Berlin, Germany
    J Cell Biol 148:1035-46. 2000
    ..The thickness of the myelin sheath is determined by the axon diameter, and we suggest that trophic signals provided by the nerve determine the number of times a Schwann cell wraps an axon...
  2. ncbi request reprint Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase
    C Birchmeier
    Dept of Medical Genetics, Max Delbrück Centrum for Molecular Medicine, Berlin, Germany
    Trends Cell Biol 8:404-10. 1998
    ..This review discusses the main features of HGF/SF and its receptor, the product of the c-met protooncogene, and their role in embryogenesis...
  3. ncbi request reprint Genes that control the development of migrating muscle precursor cells
    C Birchmeier
    Max Delbrueck Centre for Molecular Medicine, Robert Roessle Strasse 10, 13092, Berlin, Germany
    Curr Opin Cell Biol 12:725-30. 2000
    ..Progress has been made in understanding patterning of the muscles, which requires a precise control of proliferation and differentiation of myogenic precursor cells...
  4. doi request reprint ErbB receptors and the development of the nervous system
    Carmen Birchmeier
    Max Delbrueck Centrum, Robert Roessle Strasse 10, D 13125 Berlin Buch, Germany
    Exp Cell Res 315:611-8. 2009
    ..Understanding the neuregulin signaling system can thus contribute to define causes of this devastating mental disorder...
  5. doi request reprint Neuregulin-1, a key axonal signal that drives Schwann cell growth and differentiation
    Carmen Birchmeier
    Max Delbrueck Centrum, Robert Roessle Strasse 10, Berlin Buch, Germany
    Glia 56:1491-7. 2008
    ..The versatility of glial responses elicited by this factor is thus clearly astounding...
  6. doi request reprint The bHLH transcription factor Olig3 marks the dorsal neuroepithelium of the hindbrain and is essential for the development of brainstem nuclei
    Robert Storm
    Max Delbrück Centrum for Molecular Medicine, Robert Rossle Strasse 10, 13125 Berlin, Germany
    Development 136:295-305. 2009
    ..We therefore propose that Olig3 can cooperate with Ptf1a to determine the fate of climbing fiber neurons of the inferior olivary nucleus...
  7. doi request reprint A transcriptional network coordinately determines transmitter and peptidergic fate in the dorsal spinal cord
    Dominique Bröhl
    Department of Neuroscience, Max Delbrück Centrum for Molecular Medicine, Berlin, Germany
    Dev Biol 322:381-93. 2008
    ..We conclude that a transcriptional network operates in maturing dorsal horn neurons that coordinately determines transmitter and peptidergic fate...
  8. ncbi request reprint Insm1 (IA-1) is a crucial component of the transcriptional network that controls differentiation of the sympatho-adrenal lineage
    Hendrik Wildner
    Max Delbrück Centrum for Molecular Medicine, Robert Rossle Strasse 10, 13125 Berlin, Germany
    Development 135:473-81. 2008
    ..We demonstrate that the fetal lethality of Insm1 mutant mice is caused by catecholamine deficiency, which highlights the importance of Insm1 in the development of the sympatho-adrenal lineage...
  9. ncbi request reprint Lbx1 acts as a selector gene in the fate determination of somatosensory and viscerosensory relay neurons in the hindbrain
    Martin A Sieber
    Department of Neuroscience, Max Delbruck Center for Molecular Medicine, Berlin, Germany
    J Neurosci 27:4902-9. 2007
    ..In Lbx1 mutant mice, viscerosensory relay neurons are specified at the expense of somatosensory relay neurons. Thus Lbx1 expression distinguishes between the somatosensory or viscerosensory fate of relay neurons...
  10. ncbi request reprint dILA neurons in the dorsal spinal cord are the product of terminal and non-terminal asymmetric progenitor cell divisions, and require Mash1 for their development
    Hendrik Wildner
    Max Delbrück Centrum for Molecular Medicine, Berlin Buch, Germany
    Development 133:2105-13. 2006
    ..Our data allow us to assign to Mash1 a function in asymmetric cell divisions, and indicate that the factor coordinates cell cycle exit and specification in the one daughter that gives rise to a dILA neuron...
  11. ncbi request reprint The development of migrating muscle precursor cells
    Elena Vasyutina
    Max Delbruck Center for Molecular Medicine, Robert Rossle Str 10, 13125, Berlin, Germany
    Anat Embryol (Berl) 211:37-41. 2006
    ..Finally, proliferation at the targets is essential to ensure a correct size of the precursor pool and of the muscle that derives thereof...
  12. pmc The tyrosine phosphatase Shp2 (PTPN11) directs Neuregulin-1/ErbB signaling throughout Schwann cell development
    Katja S Grossmann
    Neuroscience Department, Department of Cancer Research, Department of Cardiovascular Research, Max Delbrück Centrum for Molecular Medicine, Robert Rossle Strasse 10, Berlin, Germany
    Proc Natl Acad Sci U S A 106:16704-9. 2009
    ..Together, our genetic and biochemical analyses demonstrate that Shp2 is an essential component in the transduction of Nrg1/ErbB signals...
  13. pmc Bace1 and Neuregulin-1 cooperate to control formation and maintenance of muscle spindles
    Cyril Cheret
    Entwicklungsbiologie Signaltransduktion, Max Delbruck Center for Molecular Medicine, Berlin, Germany
    EMBO J 32:2015-28. 2013
    ..Our results assign to Bace1 a role in the control of coordinated movement through its regulation of muscle spindle physiology, and implicate IgNrg1-dependent processing as a molecular mechanism...
  14. pmc The transcription factor c-Maf in sensory neuron development
    Hagen Wende
    Developmental Biology, Max Delbruck Center for Molecular Medicine, Berlin, Germany
    Transcription 3:285-9. 2012
    ..Here we discuss the recent progress made in understanding c-Maf function in the nervous system...
  15. doi request reprint The tyrosine phosphatase Shp2 in development and cancer
    Katja S Grossmann
    Department of Cancer Research, Max Delbrueck Center for Molecular Medicine, Berlin, Germany
    Adv Cancer Res 106:53-89. 2010
    ....
  16. ncbi request reprint beta-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system
    Dietmar Zechner
    Max Delbrück Center of Molecular Medicine, Robert Rossle Str 10, 13125, Berlin, Germany
    Dev Biol 258:406-18. 2003
    ..beta-Catenin signals are thus essential for the maintenance of proliferation of neuronal progenitors, controlling the size of the progenitor pool, and impinging on the decision of neuronal progenitors to proliferate or to differentiate...
  17. doi request reprint The transcription factor c-Maf controls touch receptor development and function
    Hagen Wende
    Developmental Biology, Max Delbruck Center MDC for Molecular Medicine, Berlin, Germany
    Science 335:1373-6. 2012
    ..Thus, our work identifies a key transcription factor specifying development and function of mechanoreceptors and their end organs...
  18. ncbi request reprint Notch function in myogenesis
    Elena Vasyutina
    Max Delbruck Center for Molecular Medicine, Berlin, Germany
    Cell Cycle 6:1451-4. 2007
    ..In these Perspectives we highlight the recent findings on the role of Notch/RBP-J signaling in the maintenance of muscle progenitor cells during embryogenesis and in the generation of satellite cells in fetal development...